BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0016.p (221 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll6988 [K] COG1802 Transcriptional regulators 79 4e-15 FN0878 [K] COG1802 Transcriptional regulators 79 6e-15 SMa0065 [K] COG1802 Transcriptional regulators 69 5e-12 mll6782 [K] COG1802 Transcriptional regulators 69 6e-12 mll6291 [K] COG1802 Transcriptional regulators 68 1e-11 >mll6988 [K] COG1802 Transcriptional regulators Length = 220 Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 4/191 (2%) Query: 16 AYDSILRDIKENQLTQGQPIIEEEYAKKLDMSRTPVREAIRLLSVEGFVTVYPRKGAYVS 75 AY+ + R ++ + G +I EE A ++ MSR PVREA R L+ +G V + P +G V+ Sbjct: 16 AYNHVQRALRLGRYKPGDRLIPEEIAAEIGMSRMPVREAFRRLASDGLVVLRPNRGCVVA 75 Query: 76 VLTAEDVKECYEMMEAVEGMIAYLAAHQPSTEHVNQLTELIGRMNEQKNLSNFHQWKEYD 135 LT +++ E +E+ +EG+ LA + E +L L+ RM E+ S W Sbjct: 76 GLTVDELFEIFEIRSVLEGLAVRLAVPRIDDEEFEELDRLLERM-ERAGQSGGGDWVVRH 134 Query: 136 IEFHRTLHRMCPNKLLIYHVEKLFHKTYQIQTR--FVAGVNLEKATEEHQFILDAIIAKD 193 EFH + + LI+ + L H + R F A EEH ++ A+ + D Sbjct: 135 QEFHGRICALSQRPKLIHQISAL-HVVIEPYMRIWFDDCNKPLSAREEHAAVIAALRSGD 193 Query: 194 SEKARHYTQQN 204 + A Q++ Sbjct: 194 AHHAEQVMQEH 204 >FN0878 [K] COG1802 Transcriptional regulators Length = 235 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 64/213 (30%), Positives = 101/213 (47%), Gaps = 18/213 (8%) Query: 16 AYDSILRDIKENQLTQGQPIIEEEYAKKLDMSRTPVREAIRLLSVEGFVTVYPRKGAYVS 75 AYD I I N+ G +E +L +SRTPVREA+ L EG++T+ +G V+ Sbjct: 22 AYDLIKDAILFNKFRIGAIYSQESICNELGISRTPVREALIELQKEGYITILRGRGIEVT 81 Query: 76 VLTAEDVKECYEMMEAVEGMIAYLAAHQPSTEHVNQLTELIGRMNEQKNLSNFHQWKEYD 135 +T ED K+ E+ E A+LAA + E + L E I ++ + NLS F Y Sbjct: 82 PVTEEDAKDILEVRIFYEKNNAFLAAKRIKDEDIKLLKECIEKL--ESNLSTFDSQLLYR 139 Query: 136 IE--FHRTLHRMCPNKLLIYHVEKLFHKTYQIQTRFV--AGVNLEKATEEHQFILDAIIA 191 I+ FHR + + N + E + + + + V ++ + +EH I +AI Sbjct: 140 IDHQFHRLVAKATQNNWMYKETELILDNYLRFENKSVYNNSIDGQLVFKEHLAIFNAIKD 199 Query: 192 KDSEKARHYTQQN------------WNRARNEL 212 KDSEKA+ +++ WN + EL Sbjct: 200 KDSEKAKKMMEKHLVNSYYRTLKKIWNTEKEEL 232 >SMa0065 [K] COG1802 Transcriptional regulators Length = 230 Score = 69.3 bits (168), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 54/177 (30%), Positives = 88/177 (49%), Gaps = 6/177 (3%) Query: 20 ILRD-IKENQLTQGQPIIEEEYAKKLDMSRTPVREAIRLLSVEGFVTVYPRKGAYVSVLT 78 ILR+ I + +L G I E E A+ L +SR PVREA L+ EG V V P++G YV+ ++ Sbjct: 23 ILREQIIQAELVPGARISEAEIARSLSISRQPVREAFIKLAEEGLVQVLPQRGTYVTRIS 82 Query: 79 AEDVKECYEMMEAVEGMIAYLAAHQPSTEHVNQLTELIGRMNE--QKNLSNFHQWKEYDI 136 V + + EA+E I A + V++L E I R + + + F + E Sbjct: 83 TASVMDVRFVREAIEADIVRQVAGEHPAAIVDELREQIARQKQVPHDDRAAFLRLDEL-- 140 Query: 137 EFHRTLHRMCPNKLLIYHVEKLFHKTYQIQTRFVAGVNLEKATEEHQFILDAIIAKD 193 FH TL +E + + +++ V + + + E+H+ I+DAI A+D Sbjct: 141 -FHHTLATAAGRAHAWSVIESVKAQMDRVRFLSVDDLQIGRLIEQHERIVDAIAARD 196 >mll6782 [K] COG1802 Transcriptional regulators Length = 224 Score = 68.9 bits (167), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 52/175 (29%), Positives = 87/175 (49%), Gaps = 7/175 (4%) Query: 27 NQLTQGQPIIEEEYAKKLDMSRTPVREAIRLLSVEGFVTVYPRKGAYVSVLTAEDVKECY 86 QL G+ I E A+ L +SRTPVREA++ +S EG V + + G YV+ ++ D++E Y Sbjct: 29 GQLKPGEVINEVAIAEALGVSRTPVREAVKRISDEGLVKILAQTGTYVAPISRADLEEAY 88 Query: 87 EMMEAVEGMIAYLAAHQPSTEHVNQLTELIGRMNEQKNLSNFHQWKEYDIEFHRTLHRMC 146 + A+E A AA + + L + + + + + D FHRT+ +C Sbjct: 89 VIRRALEMESARRAAAKLTPASAELLEDNMAAHKLAISRGRYATAIQLDDVFHRTIAEIC 148 Query: 147 PNKLLIYHVEKLFHKTYQIQTRFVA----GVNLEKATEEHQFILDAIIAKDSEKA 197 ++ V+ K + R++A G E+ E+H+ ILDA+ D+E A Sbjct: 149 GLPMIWRAVD--ISKAQMDRGRYLAIPKPGYG-EQTIEQHEAILDALKRHDAEGA 200 >mll6291 [K] COG1802 Transcriptional regulators Length = 232 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 49/190 (25%), Positives = 88/190 (46%), Gaps = 5/190 (2%) Query: 7 MGKQNQAQIAYDSILRDIKENQLTQGQPIIEEEYAKKLDMSRTPVREAIRLLSVEGFVTV 66 + +Q+ + +S+ I + +G P+I+E A + + SR PVREA R L G + Sbjct: 13 LQRQSLPEALSESLRERILSGEFKEGDPLIQEAIAAEYECSRMPVREAFRQLEAAGLIVS 72 Query: 67 YPRKGAYVSVLTAEDVKECYEMMEAVEGMIAYLAAHQPSTEHVNQLTELIGRMNEQKNLS 126 KGA VS L +E + E +E+ +E I + S E + +++ R+ E + Sbjct: 73 KIHKGAIVSTLPSEQIMELFELRATLECDILSRSLEHLSDEELAHSAQILKRLEEAYHKR 132 Query: 127 NFHQWKEYDIEFHRTLHRMCP---NKLLIYHVEKLFHKTYQIQTRFVAGVNLEKATEEHQ 183 + + + EFHR+L+R ++ + + +IQ +G E+A EH+ Sbjct: 133 DIARVGALNWEFHRSLYRPAGRIQTLAILQGINVQIDRYIRIQLLLTSG--FEEAEREHR 190 Query: 184 FILDAIIAKD 193 IL +D Sbjct: 191 QILSMCKERD 200 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.132 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,772,208 Number of extensions: 633105 Number of successful extensions: 1475 Number of sequences better than 1.0e-05: 83 Number of HSP's gapped: 1467 Number of HSP's successfully gapped: 83 Length of query: 221 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 119 Effective length of database: 26,614,363 Effective search space: 3167109197 Effective search space used: 3167109197 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)