BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0004.p (317 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_prsA [O] COG0760 Parvulin-like peptidyl-prolyl isomerase 431 e-121 lin0238 [FE] COG0462 Phosphoribosylpyrophosphate synthetase 413 e-115 L25614 [FE] COG0462 Phosphoribosylpyrophosphate synthetase 371 e-103 CAC3221 [FE] COG0462 Phosphoribosylpyrophosphate synthetase 370 e-102 SP0027 [FE] COG0462 Phosphoribosylpyrophosphate synthetase 356 3e-98 >BS_prsA [O] COG0760 Parvulin-like peptidyl-prolyl isomerase Length = 315 Score = 431 bits (1109), Expect = e-121, Method: Compositional matrix adjust. Identities = 0/312 (0%), Positives = 0/312 (0%) Query: 3 YCDSKLKIFTCNSNPKLASQIADYIGIPMGESHTTSFSDGEIQVKLSESVRGCHVYIVQS 62 + + S V+ + + Sbjct: 5 KLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTN 64 Query: 63 TCGPVNDNLMELLVMVDALKRASAKSINVVIPYYGYARQDRKARSRDPITAKLVANLIEK 122 +++ L A + + R R + + L + +++ Sbjct: 65 DNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDR 124 Query: 123 AGAHRVITMDLHAMQIQGFFDIPVDHLLGVPILAQYFRSKQIQNPVVVSPDHGGVVRARK 182 + + ++ +L +L + + +P + + Sbjct: 125 VLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLL 184 Query: 183 LADFLNAPLAIIDKRRPEPNVSEVMNIIGNIEGKXXXXXXXXXXXXXXXVLGANALMEGG 242 + + + + ++ G + Sbjct: 185 NDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRV 244 Query: 243 VKEVYACCTHPVLSGPAHERLENSPIKEIIVTDTIPIRSNNPTSKLKVLSVAPLMGEAII 302 + + + + + + I+S L + + I Sbjct: 245 FAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRIS 304 Query: 303 RVHEELSISKLF 314 Sbjct: 305 316 >lin0238 [FE] COG0462 Phosphoribosylpyrophosphate synthetase Length = 346 Score = 413 bits (1061), Expect = e-115, Method: Compositional matrix adjust. Identities = 20/314 (6%), Positives = 47/314 (14%), Gaps = 1/314 (0%) Query: 3 YCDSKLKIFTCNSNPKLASQIADYIGIPMGESHTTSFSDGEIQVKLSESVRGCHVYIVQS 62 + + + + + Sbjct: 5 RIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 63 TCGPVNDNLMELLVMVDALKRASAKSINVVIPYYGYARQDRKARSRDPITAKLVANLIEK 122 T V + L + + + + Q ++ + L Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 123 AGAHRVITMDLHAMQIQGFFDIPVDHLLGVPILAQYFRSKQIQNP-VVVSPDHGGVVRAR 181 + G L + + A Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAF 184 Query: 182 KLADFLNAPLAIIDKRRPEPNVSEVMNIIGNIEGKXXXXXXXXXXXXXXXVLGANALMEG 241 + +L+ R + G LG L Sbjct: 185 GVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGK 244 Query: 242 GVKEVYACCTHPVLSGPAHERLENSPIKEIIVTDTIPIRSNNPTSKLKVLSVAPLMGEAI 301 + L K + I R +++ + V A Sbjct: 245 YLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAS 304 Query: 302 IRVHEELSISKLFE 315 + Sbjct: 305 TLLGATTMDQLKTN 318 >L25614 [FE] COG0462 Phosphoribosylpyrophosphate synthetase Length = 346 Score = 371 bits (952), Expect = e-103, Method: Compositional matrix adjust. Identities = 20/319 (6%), Positives = 60/319 (18%), Gaps = 5/319 (1%) Query: 1 MTYCDSKLKIFTCNSNPKLASQIADYIGIPMGESHTTSFSDGEIQVKLSESVRGCHVYIV 60 M Y ++ + + + ++H + L + V Sbjct: 1 MQY--HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 61 QSTCGPVNDNLMELLVMVDALKRASAKSINVVIPYYGYARQDRKARSRDPITAKLVANLI 120 T G + L + ++ S + + + + Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 121 EKAGAHRVITMDLHAMQIQGFFDIPVDHLLGVPILAQYFRSKQI---QNPVVVSPDHGGV 177 ++ + +H Q + + A + + GV Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGV 178 Query: 178 VRARKLADFLNAPLAIIDKRRPEPNVSEVMNIIGNIEGKXXXXXXXXXXXXXXXVLGANA 237 LA + +++ Sbjct: 179 SNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGF 238 Query: 238 LMEGGVKEVYACCTHPVLSGPAHERLENSPIKEIIVTDTIPIRSNNPTSKLKVLSVAPLM 297 G A + + + + V + I + ++ Sbjct: 239 GTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRR 298 Query: 298 GEAIIRVHEELSISKLFEI 316 + + + Sbjct: 299 QPFVASTLLGATTMDQLKT 317 >CAC3221 [FE] COG0462 Phosphoribosylpyrophosphate synthetase Length = 346 Score = 370 bits (951), Expect = e-102, Method: Compositional matrix adjust. Identities = 16/312 (5%), Positives = 48/312 (15%), Gaps = 2/312 (0%) Query: 8 LKIFTCNSNPKLASQIADYIGIPMGESHTTSFSDGEIQVKLSESVRGCHVYIVQSTCGPV 67 ++ + + I + + Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 68 NDNLMELLVMVDALKRASAKSINVVIPYYGYARQDRKARSRDPITAKLVANLIEKAGAHR 127 ++K R D+ ++ A + + Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 128 VITMDLHAMQIQGFFDIPVDHLLGVPILAQYF--RSKQIQNPVVVSPDHGGVVRARKLAD 185 + + F + P ++ + G Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVM 187 Query: 186 FLNAPLAIIDKRRPEPNVSEVMNIIGNIEGKXXXXXXXXXXXXXXXVLGANALMEGGVKE 245 D R + + + E + G Sbjct: 188 RYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLN 247 Query: 246 VYACCTHPVLSGPAHERLENSPIKEIIVTDTIPIRSNNPTSKLKVLSVAPLMGEAIIRVH 305 R ++ + R + L+ + Sbjct: 248 GAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLL 307 Query: 306 EELSISKLFEIE 317 ++ +L Sbjct: 308 GATTMDQLKTNI 319 >SP0027 [FE] COG0462 Phosphoribosylpyrophosphate synthetase Length = 346 Score = 356 bits (914), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 20/321 (6%), Positives = 56/321 (17%), Gaps = 6/321 (1%) Query: 1 MTYCDSKLKIFTCNSNPKLASQIADYIGIPMGESHTTSFSDGEIQVKLSESVRGCHVYIV 60 M Y + + + + ++H + L + V Sbjct: 1 MQYHR--IPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 61 QSTCGPVNDNLMELLVMVDALKRASAKSINVVIPYYGYARQDRKARSRDPITAKLVANLI 120 T G + L + ++ S + + + + Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSL 118 Query: 121 EKAGAHRVITMDLHAMQIQGFFDIPVDHLLGVPILAQYFRSKQI--QNPVVVSPDHGGVV 178 ++ + +H Q + + A V Sbjct: 119 KRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGV 178 Query: 179 RARKLADFLNAPLAIIDKRRP--EPNVSEVMNIIGNIEGKXXXXXXXXXXXXXXXVLGAN 236 + P + + + E Sbjct: 179 SNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGF 238 Query: 237 ALMEGGVKEVYACCTHPVLSGPAHERLENSPIKEIIVTDTIPIRSNNPTSKLKVLSVAPL 296 + G R ++ + R + L+ Sbjct: 239 GTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRR 298 Query: 297 MGEAIIRVHEELSISKLFEIE 317 + ++ +L Sbjct: 299 QPFVASTLLGATTMDQLKTNI 319 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,076,658 Number of extensions: 820744 Number of successful extensions: 1266 Number of sequences better than 1.0e-05: 27 Number of HSP's gapped: 1196 Number of HSP's successfully gapped: 30 Length of query: 317 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 211 Effective length of database: 26,153,027 Effective search space: 5518288697 Effective search space used: 5518288697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)