BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0015.p (340 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1928 [K] COG1609 Transcriptional regulators 241 1e-63 PM0547 [K] COG1609 Transcriptional regulators 195 1e-49 lin0030 [K] COG1609 Transcriptional regulators 182 7e-46 HI1635 [K] COG1609 Transcriptional regulators 175 8e-44 CAC0360 [K] COG1609 Transcriptional regulators 172 5e-43 >BH1928 [K] COG1609 Transcriptional regulators Length = 335 Score = 241 bits (616), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 132/331 (39%), Positives = 193/331 (58%), Gaps = 3/331 (0%) Query: 5 IKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLIG 64 I IA+ G S++TVSK++NNY+DVS+K +K+VM+ + + GY PS+SA+ L TKKS IG Sbjct: 4 IYDIAKKTGYSITTVSKVLNNYTDVSDKARKKVMDAVTEMGYFPSSSARMLTTKKSWTIG 63 Query: 65 VIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISSGDYYSRCLHFNVDGC 124 V+F + HPFF V+ FKK + GYDL+F SN+ + Y + VDG Sbjct: 64 VVFVESAGIGMEHPFFSSVIENFKKNVERFGYDLLFASNQIGNEAKTYLEHFRYRGVDGI 123 Query: 125 VIISGQKMEPAIRDLDMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGHREL 184 V++ +P + L + IP + +DL+ +G S V SDN + V++ LGHR + Sbjct: 124 VVVCSLLNDPEVEKLMKADIPSVVIDLDSKG--SSAVYSDNEYGSELAVDYLVSLGHRSI 181 Query: 185 GFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLESGSMP 244 I + QR GF A++ L+++ + V G F G AM LL + P Sbjct: 182 AHISGDQGLFVGVQRLKGFKDAIQKLNLSISDEYIVDGGFFTYEGGQRAMEALLRNRVRP 241 Query: 245 QAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERLGVL 304 AV+AA DL+ALGAI +++ GL +PED +I+G DDI+ +YT+P LTTIRQN + +G Sbjct: 242 TAVYAAGDLMALGAIDTIRKHGLSVPEDFSIVGFDDIQMIRYTAPALTTIRQNTDLIGKT 301 Query: 305 AAHMLYDLIN-NQSDGGSFVVEPALIVRESC 334 AA++L D IN N+ S + LI R+SC Sbjct: 302 AANLLLDQINENEKQSLSVKIPVTLIERDSC 332 >PM0547 [K] COG1609 Transcriptional regulators Length = 334 Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 109/338 (32%), Positives = 191/338 (56%), Gaps = 11/338 (3%) Query: 5 IKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLIG 64 IK +A+MAGVS +TVS +IN V+ +T+K V++ I++ YSPS A++L + IG Sbjct: 4 IKDVAKMAGVSTTTVSHVINKTRFVAAETEKLVLQAIQELNYSPSAVARSLKVNTTKSIG 63 Query: 65 VIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSNEKFISS-GDYYSRCLHFNVDG 123 +I P+F E+++A ++ GY L + + + ++ + VDG Sbjct: 64 MIVTSS-----EAPYFAEIIHAVEEHCYRQGYSLFLCNTQNNVEKIKNHLEMLIKKRVDG 118 Query: 124 CVIISGQKMEPAIRDL-DMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGHR 182 +++ + + ++ L + +S+P + +D K + + + + ++ GH+ Sbjct: 119 ILVMCAEYTQDSLDLLANFTSLPLVVMDWGPDNKHTDIIQDHSFEGGYLATKYLIDHGHK 178 Query: 183 ELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESS-GYTAMRRLLESG 241 ++G I + R GF+KA+ GL +N +W + G FFE GY M ++L Sbjct: 179 DIGIIAGELTKTTAKTRYEGFIKAMNEAGLKINPDWVMEG--FFEPEDGYECMNKILAQD 236 Query: 242 SMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERL 301 ++P AVF +D++ALGAI A+ E+GLR+PED++IIG D+I A ++ SP LTTI Q+K RL Sbjct: 237 TLPTAVFCCNDVMALGAISAIGEKGLRVPEDISIIGYDNIHASRFYSPPLTTIHQSKSRL 296 Query: 302 GVLAAHMLYDLINNQSDGGSFV-VEPALIVRESCGSKL 338 G A +L++ IN +S+ + + + P L++R+S S+L Sbjct: 297 GARAVTLLFERINEKSEERAVIEMHPELVIRKSVKSRL 334 >lin0030 [K] COG1609 Transcriptional regulators Length = 351 Score = 182 bits (462), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 114/356 (32%), Positives = 192/356 (53%), Gaps = 26/356 (7%) Query: 2 QLNIKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSS 61 ++ I++IA+++GVSVSTVS++INN VS +K++ II++ Y+PS A+ + K++ Sbjct: 3 KITIQEIAKLSGVSVSTVSRVINNSPSVSAAKRKKIQAIIDEHNYTPSVFARGMVNKQTK 62 Query: 62 LIGVIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFS---------NEKF-ISSGD 111 IGVI + ++P+F+ ++ +K + I F+ N K ++ D Sbjct: 63 NIGVILP-----DISNPYFISLITQIQKFALDYMFSTILFNTMLAEPNNKNSKHPLTEED 117 Query: 112 YYSRCLHFNVDGCVIISGQKMEP--------AIRDLDMSSIPCIGVDLELRGKKSGYVMS 163 Y L VDG +I+ G+ + A+ L+ IP + + ++ ++ Sbjct: 118 YLKIILEKQVDGLLILGGEIDKEVVSKDYINALNQLN-REIPVVVIGSKIPELNCLFIER 176 Query: 164 DNVQIASKVVEHFYLLGHRELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGD 223 + + + +V H L H+ +GFIG A I++ R F A+ S+ ++N +W V D Sbjct: 177 NLKKGITTLVSHLTALDHKNIGFIGGEAGVKITSYRLESFKAAMASYNHSVNEDWIVLSD 236 Query: 224 DFFESSGYTAMRRLLESGS-MPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIE 282 ++ + GY AM +LLE+ + +P A+ A +D +A+GAIRA+ + L PED+AI+ CD Sbjct: 237 -YYTADGYAAMTKLLENNTTLPTALVAINDNVAIGAIRAINDAKLSCPEDIAIVSCDQFM 295 Query: 283 ACKYTSPTLTTIRQNKERLGVLAAHMLYDLINNQSDGGSFVVEPALIVRESCGSKL 338 Y +P LT++ Q+ E LG +A L IN Q + P LI+RESCGSKL Sbjct: 296 NGDYQTPRLTSMDQHNEYLGKMALLQLISAINGQVEPMIINHNPELIIRESCGSKL 351 >HI1635 [K] COG1609 Transcriptional regulators Length = 336 Score = 175 bits (444), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 116/348 (33%), Positives = 188/348 (54%), Gaps = 27/348 (7%) Query: 4 NIKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSLI 63 IK +A+MAGVS +TVS +IN V++ T++ V+ I+Q YSPS A++L + I Sbjct: 3 TIKDVAKMAGVSTTTVSHVINKTRFVAKDTEEAVLSAIKQLNYSPSAVARSLKVNTTKSI 62 Query: 64 GVIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFFSN----EKFISSGDYYSRCLHF 119 G+I P+F E++++ ++ GY L ++ EK + + ++ Sbjct: 63 GMIVTTS-----EAPYFAEIIHSVEEHCYRQGYSLFCVTHKMDPEKVKNHLEMLAK---K 114 Query: 120 NVDGCVIISGQKMEPAIRDLD-MSSIPCIGVDLELRGKKSGYVMSDNV----QIASKVVE 174 VDG +++ + + ++ L S+IP + +D V+ D+ +A+K Sbjct: 115 RVDGLLVMCSEYTQDSLDLLSSFSTIPMVVMDWGPNANTD--VIDDHSFDGGYLATK--- 169 Query: 175 HFYLLGHRELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAM 234 H GH+++G I + + R GF KA+E LT+N +W + G F GY M Sbjct: 170 HLIECGHKKIGIICGELNKTTARTRYEGFEKAMEEAKLTINPSWVLEGA-FEPEDGYECM 228 Query: 235 RRLLESGSMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTI 294 RLL +P A+F +D++ALGAI AL E+GLR+PED++IIG DDI A ++ +P LTTI Sbjct: 229 NRLLTQEKLPTALFCCNDVMALGAISALTEKGLRVPEDMSIIGYDDIHASRFYAPPLTTI 288 Query: 295 RQNKERLGVLAAHMLYDLINNQSDG----GSFVVEPALIVRESCGSKL 338 Q+K RLG A ++L + I ++ +G + P LI+R+S S L Sbjct: 289 HQSKLRLGRQAINILLERITHKDEGVQQYSRIDITPELIIRKSVKSIL 336 >CAC0360 [K] COG1609 Transcriptional regulators Length = 328 Score = 172 bits (437), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 103/335 (30%), Positives = 183/335 (54%), Gaps = 11/335 (3%) Query: 3 LNIKKIAEMAGVSVSTVSKIINNYSDVSEKTKKRVMEIIEQTGYSPSNSAKTLATKKSSL 62 ++IK IA GVS TVS+ +NN D++E TK++++++ E+ Y P+++AK+L TKK+++ Sbjct: 2 VSIKDIARYCGVSAMTVSRALNNSDDIAEATKEKILKVCEELKYKPNSAAKSLITKKTNM 61 Query: 63 IGVIFAGELNVEFTHPFFVEVLNAFKKQMGVLGYDLIFF-SNEKFISSGDYYSRCLHFNV 121 IG+I + + ++ + + GY LI SN K + Y V Sbjct: 62 IGLIIP-----DIANQYYANISKGVSSYIEKHGYGLILCNSNRKKPNEVKYLDFLSEGRV 116 Query: 122 DGCVIISGQKMEPAIRDLDMSSIPCIGVDLELRGKKSGYVMSDNVQIASKVVEHFYLLGH 181 DG +I+ + + D+ IP + D +G + +V DN A K++ H G+ Sbjct: 117 DGIIILPVKPRKEDYEDIS-RQIPMVMADNFAKGLEVNFVGIDNYAGAIKIITHMVNQGY 175 Query: 182 RELGFIGSTADSDISNQREAGFVKAVESFGLTLNRNWFVHGDDFFESSGYTAMRRLLESG 241 +++G I DS S++R G+ K +E G++ N + +H + FE G+ L+E G Sbjct: 176 KKIGVILGDKDSTASSERLNGYKKVLEDKGISYNEDIVIHSNSTFE-DGFNIASILIEKG 234 Query: 242 SMPQAVFAASDLLALGAIRALKEQGLRIPEDVAIIGCDDIEACKYTSPTLTTIRQNKERL 301 ++FA +D +A+G I+ E+G+++PE++ + G D+IE + LTT+ Q+ +++ Sbjct: 235 V--DSIFAINDTVAMGVIKYCYEKGIKLPEELGLAGYDNIEQAAMLTIPLTTVDQDNKKI 292 Query: 302 GVLAAHMLYDLIN-NQSDGGSFVVEPALIVRESCG 335 G +AA ML D I N ++EP L++R+SCG Sbjct: 293 GTIAAKMLVDAIKGNAKKTEKIILEPTLVIRKSCG 327 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,761,330 Number of extensions: 959487 Number of successful extensions: 2787 Number of sequences better than 1.0e-05: 178 Number of HSP's gapped: 2498 Number of HSP's successfully gapped: 181 Length of query: 340 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 233 Effective length of database: 26,037,693 Effective search space: 6066782469 Effective search space used: 6066782469 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)