BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0027.p (448 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO4097 [L] COG0593 ATPase involved in DNA replication initiation 396 e-110 ZdnaA [L] COG0593 ATPase involved in DNA replication initiation 389 e-108 ECs4637 [L] COG0593 ATPase involved in DNA replication initiation 389 e-108 ZdnaA [L] COG0593 ATPase involved in DNA replication initiation 388 e-108 dnaA [L] COG0593 ATPase involved in DNA replication initiation 388 e-108 >YPO4097 [L] COG0593 ATPase involved in DNA replication initiation Length = 673 Score = 396 bits (1018), Expect = e-110, Method: Compositional matrix adjust. Identities = 30/454 (6%), Positives = 89/454 (19%), Gaps = 23/454 (5%) Query: 8 LWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYTKLVGATV 67 QQ T T+ + A +I A +T + Sbjct: 5 PGQQQAVEFVTGPCLVLAGAGSGKTRV-ITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 68 YEVTGEQVEV-KFVIEE---------------NKPAEPVVQQTAPSPAVSREEAQTHL-- 109 E G+ + + + + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 110 ---LNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHY 166 + S + A + + +F + + + Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 167 VLEHNPNNKVIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQE 226 ++ + E E +++ + + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 227 EFFHTFNALHEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRK 286 + + +++S D P ++ LE+ RS +I + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 287 KAKAENLDIPNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIP 346 ++ + ++ + EL + + + + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFL- 362 Query: 347 SSRPKMITIGDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGE 406 I + + + + + K Sbjct: 363 MQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLG 422 Query: 407 AFGGRDHTTVIHAHEKITQSLKVDQELYKVVNNL 440 + + ++ A + S + Y+ + Sbjct: 423 EWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRF 456 >ZdnaA [L] COG0593 ATPase involved in DNA replication initiation Length = 673 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 33/459 (7%), Positives = 86/459 (18%), Gaps = 28/459 (6%) Query: 8 LWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRY-------- 59 QQ T T+ + A +I A + Sbjct: 5 PGQQQAVEFVTGPCLVLAGAGSGKTRV-ITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 60 TKLVGATV----YEVTGEQVEV--KFVIEENKPAEPVVQQTAPSPAVSR----------- 102 + VG T+ I + + A ++ + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 103 -EEAQTHLLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMH 161 E LL + + + AA+ A+ E + LY L Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 162 AIGHYVLEHNPNNKVIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGK 221 + + ++ + + + + + + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 222 ESTQEEFFHTFNALHEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRI 281 + + + Q + E + LI + + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 282 AILRKKAKAENLDIPNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEAL 341 + L A+ + L NE + + + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLM 363 Query: 342 KDIIPSSRPKMITIGDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSL 401 ++ I + T + ++ + + + + Sbjct: 364 QNRI-PYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLG 422 Query: 402 PKIGEAFGGRDHTTVIHAHEKITQSLKVDQELYKVVNNL 440 + + + Sbjct: 423 EWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLA 461 >ECs4637 [L] COG0593 ATPase involved in DNA replication initiation Length = 673 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 33/459 (7%), Positives = 86/459 (18%), Gaps = 28/459 (6%) Query: 8 LWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRY-------- 59 QQ T T+ + A +I A + Sbjct: 5 PGQQQAVEFVTGPCLVLAGAGSGKTRV-ITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 60 TKLVGATV----YEVTGEQVEV--KFVIEENKPAEPVVQQTAPSPAVSR----------- 102 + VG T+ I + + A ++ + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 103 -EEAQTHLLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMH 161 E LL + + + AA+ A+ E + LY L Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 162 AIGHYVLEHNPNNKVIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGK 221 + + ++ + + + + + + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 222 ESTQEEFFHTFNALHEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRI 281 + + + Q + E + LI + + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 282 AILRKKAKAENLDIPNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEAL 341 + L A+ + L NE + + + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLM 363 Query: 342 KDIIPSSRPKMITIGDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSL 401 ++ I + T + ++ + + + + Sbjct: 364 QNRI-PYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLG 422 Query: 402 PKIGEAFGGRDHTTVIHAHEKITQSLKVDQELYKVVNNL 440 + + + Sbjct: 423 EWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLA 461 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 33/459 (7%), Positives = 88/459 (19%), Gaps = 28/459 (6%) Query: 8 LWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYTKLVGATV 67 QQ T T+ + A +I A +T + Sbjct: 5 PGQQQAVEFVTGPCLVLAGAGSGKTRV-ITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 68 YEVTGEQV-EVKF-------------VIEENKPAEPVVQQTAPSPAVSR----------- 102 E G+ + + I + + A ++ + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 103 -EEAQTHLLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMH 161 E LL + + + AA+ A+ E + LY L Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 162 AIGHYVLEHNPNNKVIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGK 221 + + ++ + + + + + + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 222 ESTQEEFFHTFNALHEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRI 281 + + + Q + E + LI + + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 282 AILRKKAKAENLDIPNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEAL 341 + L A+ + L NE + + + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLM 363 Query: 342 KDIIPSSRPKMITIGDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSL 401 ++ I + T + ++ + + + + Sbjct: 364 QNRI-PYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLG 422 Query: 402 PKIGEAFGGRDHTTVIHAHEKITQSLKVDQELYKVVNNL 440 + + + Sbjct: 423 EWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLA 461 >dnaA [L] COG0593 ATPase involved in DNA replication initiation Length = 673 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 33/459 (7%), Positives = 88/459 (19%), Gaps = 28/459 (6%) Query: 8 LWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYTKLVGATV 67 QQ T T+ + A +I A +T + Sbjct: 5 PGQQQAVEFVTGPCLVLAGAGSGKTRV-ITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 68 YEVTGEQV-EVKF-------------VIEENKPAEPVVQQTAPSPAVSR----------- 102 E G+ + + I + + A ++ + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 103 -EEAQTHLLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMH 161 E LL + + + AA+ A+ E + LY L Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 162 AIGHYVLEHNPNNKVIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGK 221 + + ++ + + + + + + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 222 ESTQEEFFHTFNALHEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRI 281 + + + Q + E + LI + + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 282 AILRKKAKAENLDIPNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEAL 341 + L A+ + L NE + + + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLM 363 Query: 342 KDIIPSSRPKMITIGDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSL 401 ++ I + T + ++ + + + + Sbjct: 364 QNRI-PYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLG 422 Query: 402 PKIGEAFGGRDHTTVIHAHEKITQSLKVDQELYKVVNNL 440 + + + Sbjct: 423 EWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLA 461 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.132 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 32,611,355 Number of extensions: 1311921 Number of successful extensions: 3490 Number of sequences better than 1.0e-05: 34 Number of HSP's gapped: 3416 Number of HSP's successfully gapped: 35 Length of query: 448 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 338 Effective length of database: 25,691,691 Effective search space: 8683791558 Effective search space used: 8683791558 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 117 (49.7 bits)