BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0019.p (274 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH4059 [K] COG1475 Predicted transcriptional regulators 340 1e-93 BS_yyaA [K] COG1475 Predicted transcriptional regulators 295 5e-80 lin2926 [K] COG1475 Predicted transcriptional regulators 281 1e-75 SA2498 [K] COG1475 Predicted transcriptional regulators 213 2e-55 CAC3731 [K] COG1475 Predicted transcriptional regulators 194 1e-49 >BH4059 [K] COG1475 Predicted transcriptional regulators Length = 283 Score = 340 bits (873), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 170/282 (60%), Positives = 219/282 (77%), Gaps = 11/282 (3%) Query: 4 MKEQFTKLFGF-------TERSSGEEVKQIPVHEVISSPYQPRTIFDDEKIDELCQTIKT 56 MK+ F++LFGF E EEV Q+P+ E++ + +QPRTIFDDE+I+EL QTI+T Sbjct: 1 MKQPFSRLFGFGDKQDQEMETGKQEEVHQLPIKEIVPNRFQPRTIFDDERIEELAQTIRT 60 Query: 57 HGVIQPIVVRVRDSLYEIIAGERRWRAVKKLGMETIPAIVREFNDSQAASIALIENLQRE 116 HG+IQPIVVR R+ YEIIAGERR+RAV LG ETIPAI++EFNDSQ AS+ALIENLQRE Sbjct: 61 HGIIQPIVVRQREGKYEIIAGERRFRAVTLLGWETIPAIIKEFNDSQTASVALIENLQRE 120 Query: 117 GLTSIEEAIAYQKLIDLHQLTQESLAQRLGKSQSTIANKIRLLQLPEQVKTALMERQITE 176 GLT++EEA+AYQKLI+LH LTQESLAQRLGK QSTIANK+RLL L E V+ A+MER+I+E Sbjct: 121 GLTAVEEAVAYQKLIELHGLTQESLAQRLGKGQSTIANKLRLLHLSEPVQQAIMERKISE 180 Query: 177 RHARSLLSLDSVEMQLKVLGEIIAKGLNVKQTEARIAFYKEVSKTKKSK----RVSYTKD 232 RHAR+LLSL ++ K+L EI+ + LNVKQTE R+ E + K K R +Y+KD Sbjct: 181 RHARALLSLKDDALETKLLEEIVEQHLNVKQTEERVKELLEDAPASKPKKKPTRKAYSKD 240 Query: 233 VRLALNTIRQSIDMVTGSGMEIKTSENDRGDHYEIVIQIPKR 274 +R+A+NTIRQS+DMV SG+++ T+E + D Y+ I+IPK+ Sbjct: 241 MRIAMNTIRQSVDMVMKSGLKVDTAEEEHEDFYQFTIRIPKK 282 >BS_yyaA [K] COG1475 Predicted transcriptional regulators Length = 283 Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 151/283 (53%), Positives = 210/283 (74%), Gaps = 13/283 (4%) Query: 4 MKEQFTKLFGFTER----------SSGEEVKQIPVHEVISSPYQPRTIFDDEKIDELCQT 53 MK F++ FG E+ ++ EE+ +IPV+ ++ + +QPRTIF DEKI EL T Sbjct: 1 MKHSFSRFFGLGEKEQEPEIAEHDTNKEEILEIPVNAIVPNRFQPRTIFSDEKIKELAMT 60 Query: 54 IKTHGVIQPIVVR--VRDSLYEIIAGERRWRAVKKLGMETIPAIVREFNDSQAASIALIE 111 I THG+IQPIVVR + YE+IAGERRWRAV+ L E IPAI+++F+D++ AS+ALIE Sbjct: 61 IHTHGIIQPIVVRHTEEEGQYELIAGERRWRAVQSLEWEKIPAIIKDFSDTETASVALIE 120 Query: 112 NLQREGLTSIEEAIAYQKLIDLHQLTQESLAQRLGKSQSTIANKIRLLQLPEQVKTALME 171 NLQRE L+SIEEA AY +L++LH LTQE+LAQRLGK QSTIANK+RLL+LP+ V+ A+ME Sbjct: 121 NLQREELSSIEEAHAYARLLELHDLTQEALAQRLGKGQSTIANKLRLLKLPQPVQEAIME 180 Query: 172 RQITERHARSLLSLDSVEMQLKVLGEIIAKGLNVKQTEARIAFYKEVSKTK-KSKRVSYT 230 ++ITERHAR+L+ L E+Q+ +L EII K LNVKQTE R+ E + K K +R +++ Sbjct: 181 KKITERHARALIPLKQPELQVTLLTEIIEKSLNVKQTEDRVVKMLEQGQRKPKPRRKAFS 240 Query: 231 KDVRLALNTIRQSIDMVTGSGMEIKTSENDRGDHYEIVIQIPK 273 +D R+A+NTIRQS+ MV SG+++ T E + ++ ++ I+IPK Sbjct: 241 RDTRIAMNTIRQSLSMVEDSGVKLNTEEEEFEEYIQLTIRIPK 283 >lin2926 [K] COG1475 Predicted transcriptional regulators Length = 284 Score = 281 bits (718), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 146/281 (51%), Positives = 205/281 (72%), Gaps = 14/281 (4%) Query: 8 FTKLFGFTERSSGEE--------VKQIPVHEVISSPYQPRTIFDDEKIDELCQTIKTHGV 59 F++LFG +++ ++ V ++P+ ++ + +QPRT+FD +KIDEL +TI+ HGV Sbjct: 3 FSRLFGKKDKNQMDDIVEEGVQRVLELPMDKIFPNQFQPRTVFDQDKIDELARTIRIHGV 62 Query: 60 IQPIVVR-VRDSLYEIIAGERRWRAVKKLGMETIPAIVREFNDSQAASIALIENLQREGL 118 IQPIVVR + YEIIAGERR+RAV L +E IPAI++ +D + A+IALIENLQRE L Sbjct: 63 IQPIVVREMEPDYYEIIAGERRFRAVLSLKLEKIPAIIQNLDDEEVAAIALIENLQREEL 122 Query: 119 TSIEEAIAYQKLIDLHQLTQESLAQRLGKSQSTIANKIRLLQLPEQVKTALMERQITERH 178 T IEEA AY+ L+D+ +TQE+LAQR+GKSQS IANK+RLL+LPE V+ A++ +QI+ERH Sbjct: 123 TPIEEAKAYRSLLDMQDVTQEALAQRVGKSQSAIANKMRLLKLPETVQEAVLNKQISERH 182 Query: 179 ARSLLSLDSVEMQLKVLGEIIAKGLNVKQTEARI----AFYKEV-SKTKKSKRVSYTKDV 233 ARSLL+L++ E Q+ +L EI NVKQTEARI K V +K K KR + ++DV Sbjct: 183 ARSLLALETEEQQVSLLQEIEENHWNVKQTEARIQEILGVKKSVATKKTKPKRQAISRDV 242 Query: 234 RLALNTIRQSIDMVTGSGMEIKTSENDRGDHYEIVIQIPKR 274 R+A+NTI+QS+ MV +GM++ +E + D Y+I IQIPK+ Sbjct: 243 RIAMNTIKQSVTMVKDNGMDLDFTEEETDDFYQITIQIPKK 283 >SA2498 [K] COG1475 Predicted transcriptional regulators Length = 279 Score = 213 bits (543), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 119/281 (42%), Positives = 182/281 (64%), Gaps = 12/281 (4%) Query: 4 MKEQFTKLFGFT---------ERSSGEEVKQIPVHEVISSPYQPRTIFDDEKIDELCQTI 54 MK+ F+KLFG E V+ I + ++ + YQPR +F+ KI EL ++I Sbjct: 1 MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESI 60 Query: 55 KTHGVIQPIVVR-VRDSLYEIIAGERRWRAVKKLGMETIPAIVREFNDSQAASIALIENL 113 HG++QPIVVR + + ++EIIAGERR+RA++ L + I+R+ +D + A +ALIEN+ Sbjct: 61 HEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENI 120 Query: 114 QREGLTSIEEAIAYQKLIDLHQLTQESLAQRLGKSQSTIANKIRLLQLPEQVKTALMERQ 173 QRE L+ +EEA AY+KL+++ TQ LA+ LGKSQS IANK+RLL+L +V L E + Sbjct: 121 QRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGK 180 Query: 174 ITERHARSLLSLDSVEMQLKVLGEIIAKGLNVKQTEARIAFYKEVSKTKKSKRVSYTKDV 233 ITERHAR++LSL E Q ++ ++IA+ LNVKQTE R+ K + K++ + + +DV Sbjct: 181 ITERHARAVLSLSDSE-QEALIEQVIAQKLNVKQTEDRVR-QKTGPEKVKAQNLRFAQDV 238 Query: 234 RLALNTIRQSIDMVTGSGMEIKTSENDRGDHYEIVIQIPKR 274 A + + +SI + +G+ ++ + D D+YEI I+I KR Sbjct: 239 TQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR 279 >CAC3731 [K] COG1475 Predicted transcriptional regulators Length = 260 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 109/264 (41%), Positives = 164/264 (62%), Gaps = 15/264 (5%) Query: 21 EEVKQIPVHEVISSPYQPRTIFDDEKIDELCQTIKTHGVIQPIVVR-VRDSLYEIIAGER 79 + V I V + ++ QPR FD + EL ++I +G+IQPI VR V D +EI+AGER Sbjct: 2 DSVLYISVDNICANSNQPRKYFDKAALKELAESIDNYGIIQPITVRKVDDDKFEIVAGER 61 Query: 80 RWRAVKKLGMETIPAIVREFNDSQAASIALIENLQREGLTSIEEAIAYQKLIDLHQLTQE 139 R+RA K G++ +P I+ + ++ ++A IAL+EN+QRE L+ +EEA AY LI+ + TQ+ Sbjct: 62 RFRAAKIAGLDKVPVILIDIDEKESAEIALLENIQRENLSYMEEAEAYYNLIEQYGYTQD 121 Query: 140 SLAQRLGKSQSTIANKIRLLQLPEQVKTALMERQITERHARSLLSLDSVEMQLKVLGEII 199 LAQ +GK QSTIANK+RLL+L V+ AL+E +TERHAR+LL L + Q+ V+ ++ Sbjct: 122 KLAQSVGKKQSTIANKLRLLKLDNNVRKALLENNLTERHARALLKLSDKKSQMSVIKSVV 181 Query: 200 AKGLNVKQTEARIAFYKEVSKTKK---------SKRVSYTKDVRLALNTIRQSIDMVTGS 250 +KGLNVK+TE I K++ K K KR+ ++ +NTI+Q D Sbjct: 182 SKGLNVKKTEELIE--KKLDKVYKKENDIASDGKKRIKGIFGSQIYINTIKQVFDKY--- 236 Query: 251 GMEIKTSENDRGDHYEIVIQIPKR 274 G++ K + D E+ + IPK+ Sbjct: 237 GIKAKYKSKELDDTIEVTVVIPKK 260 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.132 0.351 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,742,267 Number of extensions: 618327 Number of successful extensions: 3052 Number of sequences better than 1.0e-05: 64 Number of HSP's gapped: 3071 Number of HSP's successfully gapped: 64 Length of query: 274 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 169 Effective length of database: 26,268,361 Effective search space: 4439353009 Effective search space used: 4439353009 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 115 (48.9 bits)