BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0005.p (578 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA0850 [E] COG0747 ABC-type dipeptide transport system, periplas... 339 7e-93 CAC0176 [E] COG0747 ABC-type dipeptide transport system, peripla... 167 3e-41 PH0807 [E] COG0747 ABC-type dipeptide transport system, periplas... 163 6e-40 CAC3179 [E] COG0747 ABC-type dipeptide transport system, peripla... 159 1e-38 FN0396 [E] COG0747 ABC-type dipeptide transport system, periplas... 129 1e-29 >SA0850 [E] COG0747 ABC-type dipeptide transport system, periplasmic component Length = 571 Score = 339 bits (870), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 194/559 (34%), Positives = 308/559 (55%), Gaps = 18/559 (3%) Query: 12 RYCGLVLAMALMLSACSGIGSERLSYGVLSNKEAEVPA-AGGTVTYGYSSPFQGLFEPAF 70 +Y ++L + L+LSAC S GV + E GGT+ ++P G++ Sbjct: 6 KYISILLIVVLVLSACGK--SSNKDEGVKDATKTETSKHKGGTLNVALTAPPSGVYSSLL 63 Query: 71 YEGEDDYQVLEFITEAMFRVKDDLTTVPGIASWQESDDHTVFTFRIRPGVRWHNGDELTV 130 D V + E++ + IASW++ + F+I+ G++WH+G+EL + Sbjct: 64 NSTHADSVVEGYFNESLLATDKKIRPKAYIASWKDIEPAKKIEFKIKKGIKWHDGNELKI 123 Query: 131 EDWKFALETIASPEYTGSRYYSVEMISGAEAFHKGKAKEISGIKVIDPYTLRITMNSVRV 190 +DW +++E +A+ +Y G+ Y SVE I GA+ +H+GK ISG+K ID YT+++T + + Sbjct: 124 DDWIYSIEVLANKDYEGAYYPSVENIQGAKDYHEGKTDHISGLKKIDDYTMQVTFDKKQE 183 Query: 191 NALDN-LWPYPMNKRVYSGIAVKDMPDSDPVRKHPIGIGPFEVTNIQPGQLVEMKAFEDY 249 N L + + ++K+ S + +KD+ SD +RK+PIGIGP++V I PG+ V++ F+DY Sbjct: 184 NYLTGFITGHLLSKKYLSDVPIKDLAKSDKIRKYPIGIGPYKVKKIVPGEAVQLVKFDDY 243 Query: 250 YQGKPLLDGVTYKVFDDKDIVNLLDENVIDMATAPRDAYASLKQLDQ--VNILQSPELSY 307 +QGKP LD + KV D I+ +++ ID+A A A + + +L +P L Y Sbjct: 244 WQGKPALDKINLKVIDQAQIIKAMEKGDIDVANDATGAMAKDAKSSNAGLKVLSAPSLDY 303 Query: 308 EYIGFKFGSWDHESQKIVMDNPKFADKRLRQAMYYALDREGIINQYSYGLGSLIETPVPS 367 IGF +D ++ K PK+ DK LR+AM YA+DRE I + G S I + VPS Sbjct: 304 GLIGFVSHDYDKKANKTGKVRPKYEDKELRKAMLYAIDREKWIKAFFNGYASEINSFVPS 363 Query: 368 SSWAKIPDSEINTYPYSPERAKALLNEAGYVDRDGDGLREDPKGAPFVIHYDAMTGST-T 426 W ++N Y Y PE+AK +L++ GY DRDGDG REDPKG F I++ +GS T Sbjct: 364 MHWIAANPKDLNDYKYDPEKAKKILDKLGYKDRDGDGFREDPKGNKFEINFKHYSGSNPT 423 Query: 427 AEARTRAILQNWRDVGLDVRLNGGQLKDLNTFYEAVENDDPSVELFNGVWGLASDPDPSG 486 E RT AI W VGL + +L + + E + N +E++ W +DPDPS Sbjct: 424 FEPRTAAIKDFWEKVGLKTNV---KLVEFGKYNEDLANASKDMEVYFRSWAGGTDPDPSD 480 Query: 487 LWREIDLWN-----YPRFSSKRNEELIREGVGIKSYDKEHRKQVYYEWQKLVNEEVPMIF 541 L+ N P+ ++ L E VGI D++ RK +Y +WQK +N+E+P + Sbjct: 481 LYHTDRPQNEMRTVLPKSDQYLDDALDFEKVGI---DEKKRKDIYVKWQKYMNDELPGLP 537 Query: 542 FAERINITAVNKRLQNVKV 560 + +IT VN +++N+ + Sbjct: 538 MFQGKSITIVNDKVRNLDI 556 >CAC0176 [E] COG0747 ABC-type dipeptide transport system, periplasmic component Length = 569 Score = 167 bits (424), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 134/502 (26%), Positives = 237/502 (47%), Gaps = 28/502 (5%) Query: 64 GLFEPAFYEGEDDYQVLEFITEAMFRVKDDLTTVPGIAS-WQESDDHTVFTFRIRPGVRW 122 G F + + D + + +T+ + D +PGIA W SDD +TF +R V++ Sbjct: 73 GNFISYYAQTLTDAYISDVVTDGLVDWDDSGEPIPGIAKKWDISDDGLTYTFHLRDDVKF 132 Query: 123 HNGDELTVEDWKFALETIASPEYTGSRYYSVEMISGAEAFHKGKAKEISGIKVIDPYTLR 182 +G LT +D KF+LE + P ++G+ +S I G +AF+KG K+I GI V DP+T+ Sbjct: 133 SDGKPLTADDVKFSLELVFDPSFSGAVDHSAIPIKGGDAFNKGTVKDIEGINVKDPHTIS 192 Query: 183 ITMNSVRVNALDNLWPYPMNKRVYSGIAV-KDMPDSDPVRKHPIGIGPFEVTNIQPGQLV 241 +T+N + L + ++K + V + + + P+G G ++VT PGQ V Sbjct: 193 VTLNKPNSSILYLIGTTIISKDYFGKDYVPGNTKGVEAKLQTPVGCGQYKVTKYVPGQEV 252 Query: 242 EMKAFEDYYQGKPLLDGVTYKVFDDKDIVNLLD--ENVIDMATAPRDAYASLKQLDQVNI 299 ++ A E Y++G P + + +K +++ + L E ID + LK + +++ Sbjct: 253 DLTANEYYWKGTPKIKNLIFKATTEENKMQNLSSGETDIDTFDGTPENIEQLKSMGFLDL 312 Query: 300 LQSPELSYEYIGFKFGSWDHESQKIVMDNPKFADKRLRQAMYYALDREGIINQYSYGLGS 359 P S YIG + + KF+D+++RQA+ Y L+R+ + G Sbjct: 313 TSFPSSSIFYIG------------VNCKDSKFSDRKVRQALEYGLNRQEMAKTVFKGNAY 360 Query: 360 LIETPVPSSSWAKIPDSEINTYPYSPERAKALLNEAGYVDRDGDGLREDPKGAPFVIHYD 419 +I P + + + D +N Y Y+ +A +L+EAG+ + DG+RE G FVIH Sbjct: 361 IINEPQSKAHASYLKD--VNEYKYNVSKANKMLDEAGW-KKGTDGIRE-KNGQKFVIHLM 416 Query: 420 AMTGSTTAEARTRAILQNWRDVGLDVRLNGGQLKDLNTFYEAVENDDPSVELFNGVWGLA 479 + + ++ + I +N++ +G+DV +L DLNT + D L L Sbjct: 417 SSSTNSAHKLEIPIIKENYKKLGIDVE---PELMDLNTLLSKTDKKDFEAYLMG--TSLG 471 Query: 480 SDPDPSGLWREIDLWNYPRFSSKRNEELIREGV--GIKSYDKEHRKQVYYEWQKLVNEEV 537 +D S L P + + + + + K DK+ R + + K +NE++ Sbjct: 472 ADALSSNLAANFKT-GAPSNNMSYSNSNVDDLIDKAYKESDKDKRTALEQKVYKDINEDL 530 Query: 538 PMIFFAERINITAVNKRLQNVK 559 P IF + I N R+ +K Sbjct: 531 PFIFTYQPETIWVNNSRVTGIK 552 >PH0807 [E] COG0747 ABC-type dipeptide transport system, periplasmic component Length = 597 Score = 163 bits (413), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 152/559 (27%), Positives = 251/559 (44%), Gaps = 66/559 (11%) Query: 8 MMKRRYCGLVLAMALMLSACSGIGSERLSYGVLSNKEAEV-PAA---GGTVTYGYSSPFQ 63 M KR + L + L++S G+ E +V P GGT+ Y + Sbjct: 1 MKKRSLFVITLFLVLVVSQL----------GIAKASEVKVFPGVKRIGGTLIVLYWGDPK 50 Query: 64 GLFEPAFYEGEDDYQVLEFITEAMFRVKDDLTTVPGIA-SWQESDDHTVFTFRIRPGVRW 122 F P + Y + I + + D +P +A W+ SDD V+TF + P W Sbjct: 51 S-FNPDAQVDDAGYGIANQIFCKLVTLDRDYNVIPDLAYKWEISDDGKVYTFYLNPNATW 109 Query: 123 HNGDELTVEDWKFALETIASPEYTGSRYYSVEMISGAEAFHKGKAKEISGIKVIDPYTLR 182 H+G +T ED K+ E I +Y G Y + A I I+V+D YT+R Sbjct: 110 HDGVPVTAEDVKWTFEAIK--KYKGIAYGIIH------------ADNIEKIEVVDNYTVR 155 Query: 183 ITMNSVRVNALDNL-W--PYPMNKRVYSGIAVKDMPD-SDPVRKHPIGIGPFEVTNIQPG 238 + L L W + + K +Y + D D +P PIG GPF+ G Sbjct: 156 FYLKEPFAPFLSFLAWYGTFILPKHIYEKYS--DWLDPKNPYLNKPIGCGPFKFVEWVKG 213 Query: 239 QLVEMKAFEDYYQGKPLLDGVTYKVFDDKDIV---NLLDENVIDMATAPRDAYASLKQLD 295 + + A E+Y++G+P +D + YK+ D L E + P LK Sbjct: 214 DHITLVANENYFRGRPGIDKIIYKIIPDASAALQAFLAGEGDVLGQRPPLTEIPRLKSTP 273 Query: 296 QVNILQSPELSYEYIGFKFGSWDHESQKIVMDNPKFADKRLRQAMYYALDREGIINQYSY 355 V++ P S Y+GF + P D R+R A+ YA++R+ ++ + Sbjct: 274 GVSVSIRPVPSRWYLGFN------------LKRPYLQDVRVRLAIAYAINRKELVEKAEN 321 Query: 356 GLGSLIE-TPVPSSSWAKIPDSEINTYPYSPERAKALLNEAGYVDRDGDGLREDPKGAPF 414 GLG E T VP+ WA P++++ Y +PE+AK LL+EAG+ D +GDG RE P G P Sbjct: 322 GLGYPAEGTYVPAIKWAYNPNAKLPEY--NPEKAKQLLDEAGFKDINGDGFRETPDGKPL 379 Query: 415 VIHYDAMTGSTTAEARTRAILQNWRDVGLDVRLNGGQLKDLNTFYEAVENDDPSVELFNG 474 + TGS T A I + VGL V+L ++ + V+ D + L +G Sbjct: 380 ELRLLYFTGSDT-NAICTLIKEQLAKVGLKVKLESYEIATWEQ--KVVKERDFDLALVDG 436 Query: 475 VWGLASDPDPSGL---WREIDLWNYPRFSSKRNEELIREGVGIKSYDKEHRKQVYYEWQK 531 G PDP+ + ++ N+ +++ ++L+ E K+ D E RK++Y++ Q+ Sbjct: 437 FQG----PDPANMEIRFKSTAYINFAGYNNTEFDKLLEEAA--KTTDTEKRKELYWKAQE 490 Query: 532 LVNEEVPMIFFAERINITA 550 ++ +++P + + + I+ Sbjct: 491 ILAKDLPYLPLVDLVAISV 509 >CAC3179 [E] COG0747 ABC-type dipeptide transport system, periplasmic component Length = 567 Score = 159 bits (403), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 161/605 (26%), Positives = 270/605 (44%), Gaps = 73/605 (12%) Query: 9 MKRRYCGLVLA---MALMLSACSGIGSERLSYG--VLSNKEAEVPAA------------G 51 MKR++ +V+ +A +LS+C+ + + V S K+ + A+ Sbjct: 1 MKRKFITVVIPSIIIASLLSSCTNTSNSTAAKATKVSSLKDQYIKASLPSKNPEKAKNRK 60 Query: 52 GTVTYGYSSPFQGLFEPAFYEGEDDYQVLEFITEAMFRVKDDLTTVPGIA-SWQESDDHT 110 T S P G+F P FY+ D + I ++ + + +A W S D+ Sbjct: 61 DTFIAAISEP-GGVFLPYFYDNGWDGNATDPIFPSLVSTDEKGNPIADLAEKWDISSDNL 119 Query: 111 VFTFRIRPGVRWHNGDELTVEDWKFALETIASPEYTGSRYYSVEMISGAEAFHKGKAKEI 170 +T+ +R +++ +G LT +D F L + P Y+GS S I G+ + GKA I Sbjct: 120 TYTYHLRKRLKFSDGSPLTSDDVAFTLTLLDDPSYSGSFDISTCYIKGSTDYKNGKATSI 179 Query: 171 SGIKVIDPYTLRITMNSVRVNALDNLWPYPMNKRVYSGIAVKDMPDS-DPVRKHPIGIGP 229 SGI V+DP T++IT + L L ++K Y K D + P+G GP Sbjct: 180 SGIAVVDPLTIKITTEKINPLNLTRLGGQVLSKAYYGKDYKKGNLDYLKSLYSRPLGAGP 239 Query: 230 FEVTNIQPGQLVEMKAFEDYYQGKPLLDGVTYKVFDDKDIVNLLDENVIDMA--TAPRDA 287 +++ PGQ + A E+YY+GKP ++ +KV + L ID + +D Sbjct: 240 YKLDKYIPGQEIRYTANENYYKGKPKIENFIFKVTSKDTNLQLFQTGEIDSDSFSTDKDT 299 Query: 288 YASLKQLDQVNILQSPELSYEYIGFKFGSWDHESQKIVMDN--PKFADKRLRQAMYYALD 345 L+ L NI S Y GF + M+N P DK +RQA+ Y LD Sbjct: 300 VDQLENLGFANIRISTVSDY---GF-----------VYMNNKKPYLKDKNVRQALIYGLD 345 Query: 346 REGIINQYSYGLGSLIETPVPSSSWAKIPDSEINTYPYSPERAKALLNEAGYVDRDGDGL 405 R+ I++ G G + P + D IN+Y ++PE+AK LL + G+ + +G+ Sbjct: 346 RQKIVDVAYKGYGEVANVPTSPLVLSYTTDG-INSYKFNPEKAKKLLEDDGW-RLNSNGI 403 Query: 406 REDPKGAPFVIHYDAMTGSTTAEARTRAILQNWRDVGLDVRLNGGQLKDLNTFYEAVEND 465 RE G I Y +T T + A +N++ +G+D ++ D NT E Sbjct: 404 RE-KNGQKLKISY--LTSKNTDQTIPIA-KENYKALGIDFE---PEIMDFNTLVE----- 451 Query: 466 DPSVELFNGVWGLASDPDPSGLWREIDLWNYPRFSSKRN------------EELIREGVG 513 +L G + LA+ SGL D + FSSK+ +ELI EGV Sbjct: 452 ----KLNKGDYDLAA-VRTSGLVDPND--SVEEFSSKKTSENVSGYFNPKVDELISEGVN 504 Query: 514 IKSYDKEHRKQVYYEWQKLVNEEVPMIFFAERINITAVNKRLQNVKVNSMSNIIDPQTWW 573 + + + RK +Y + K ++++ P+I R + A N R++ ++ ++ + + Sbjct: 505 --TLNVKKRKAIYKKLYKELSDDPPVILIDYRKGLKAWNSRIKGMENDNFAGVSSTNLSK 562 Query: 574 IQEEN 578 ++ EN Sbjct: 563 LKIEN 567 >FN0396 [E] COG0747 ABC-type dipeptide transport system, periplasmic component Length = 511 Score = 129 bits (324), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 143/577 (24%), Positives = 254/577 (44%), Gaps = 102/577 (17%) Query: 9 MKRRYCGLVLAMAL---MLSACSGIGSERLSYGVLSNKEAEVPAAGGTVTYGYSSPFQGL 65 MK+++ L++AM L L AC G ++ G ++ T+ G + + L Sbjct: 1 MKKKFW-LLMAMVLSVLFLVACGGDPDKKSDAGAGGKRD--------TLVIGNGADAKSL 51 Query: 66 FEPAFYEGEDDYQVLEFITEAMFRVKDDLTTVPGIA-SWQESDDHTVFTFRIRPGVRWHN 124 +P V I + + + DD P +A SW+ DD T+ F +R GV++HN Sbjct: 52 -DPHASNDNPSSNVRVQIFDTLMDLDDDGIPQPMLAESWERPDDKTII-FHLRKGVKFHN 109 Query: 125 GDELTVEDWKFALE-TIASPEYTGSRYYSVEMISGAEAFHKGKAKEISGIKVIDPYTLRI 183 GDE+ D KF+LE + SPE + +++G I+G++V+D YT+++ Sbjct: 110 GDEMKASDVKFSLERALKSPEVS-------HILAG-----------INGVEVLDDYTVKV 151 Query: 184 TMNSVRVNALDNLWPYPMNKRVYSGIAVKDMPDSDPVRKHPIGIGPFEVTNIQPGQLVEM 243 T L+NL + + S A + D ++PIG GP++ + Q G + + Sbjct: 152 TTEKPMAAILNNLSHTTI--AILSEKATTEA--GDKFGQNPIGTGPYKFVSWQSGDRITL 207 Query: 244 KAFEDYYQGKPLLDGVTYKVFDDKDIVNLLDEN--VIDMATAPRDAYASLKQLDQ----- 296 +AF DY++G+ + + ++ N+++E I + T D +K LD+ Sbjct: 208 EAFPDYWRGETPVKNIVFR--------NIVEETNRTIGLETGELDIAYDIKGLDKNKLKE 259 Query: 297 ---VNILQSPELSYEYIGFKFGSWDHESQKIVMDNPKFADKRLRQAMYYALDREGIINQY 353 +L+ P++S Y+GF +K DN K +R+A+ YA+D++ II+ Sbjct: 260 DERFTLLEGPQVSITYLGFNL-------RKAPYDNLK-----VREAISYAIDQKPIIDTV 307 Query: 354 SYGLGSLIETPVPSSSWAKIPDSEINTYPYSPERAKALLNEAGYVDRDGDGLREDPKGAP 413 G G + + + W ++ Y E+AKALL EAGY P G Sbjct: 308 FLGAGEPANSIIGPNIWGYY---DVEKYTQDIEKAKALLVEAGY-----------PNGFK 353 Query: 414 FVIHYDAMTGSTTAEARTRAILQN-WRDVGLDVRLNGGQLKDLNTFYEAVENDDPSVELF 472 I + T ILQ+ + +G+D+ + + + F + D + L Sbjct: 354 AKIWVN----DNPVRRDTAVILQDQLKQIGIDLTI---ETVEWGAFLDGTARGDHEMYLL 406 Query: 473 NGVWGLAS-DPDPSGLWREID------LWNYPRFSSKRNEELIREGVGIKSYDKEHRKQV 525 WG + DPD G++ I N +S+ ++L+ G D E RK + Sbjct: 407 G--WGTVTRDPD-YGMFELISSSTMGAAGNRSFYSNPEVDKLLE--AGKTELDPEKRKDI 461 Query: 526 YYEWQKLVNEEVPMIFFAERINITAVNKRLQNVKVNS 562 Y + Q++V ++PM + K ++N K+++ Sbjct: 462 YKQIQEIVRRDIPMYMIVYPLQNVITKKDVKNFKLDA 498 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.135 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 46,418,103 Number of extensions: 2185146 Number of successful extensions: 5668 Number of sequences better than 1.0e-05: 163 Number of HSP's gapped: 5411 Number of HSP's successfully gapped: 163 Length of query: 578 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 466 Effective length of database: 25,461,023 Effective search space: 11864836718 Effective search space used: 11864836718 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 119 (50.4 bits)