BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0027.0003.p
         (152 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CAC3674 [R] COG0517 FOG: CBS domain                                   165   2e-41
BH2710 [R] COG0517 FOG: CBS domain                                    144   5e-35
CAC3008 [R] COG0517 FOG: CBS domain                                    88   4e-18

>CAC3674 [R] COG0517 FOG: CBS domain
          Length = 140

 Score =  165 bits (418), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 77/129 (59%), Positives = 99/129 (76%), Gaps = 1/129 (0%)

Query: 12  MNIAFFLLPKQEVACVTLDSTLRQTLERMEFHRYTAVPILNRNGEYAGTVTEGDLLWYMK 71
           MNIAFFL PK EV    + ST+RQ LERME+HRYTA+PIL+ NG+Y GT+TEGDLLW +K
Sbjct: 1   MNIAFFLTPKNEVIYEKITSTMRQALERMEYHRYTAIPILDDNGKYIGTLTEGDLLWKLK 60

Query: 72  DSGGAVTFENASKYLLKDVPLRMNNLPVSIDADMEDLINLAKVQNFVPVVDDMNRFIGIV 131
           ++   + F+  +K  +KD+P  MNN PV ID+D+EDLI+ +  QNFVPVVDD N FIGI+
Sbjct: 61  NT-PEIDFQTTNKVSIKDIPRHMNNRPVHIDSDIEDLISKSVSQNFVPVVDDNNVFIGII 119

Query: 132 RRSQIIEYC 140
           +RS I+ YC
Sbjct: 120 KRSDIMNYC 128


>BH2710 [R] COG0517 FOG: CBS domain
          Length = 144

 Score =  144 bits (363), Expect = 5e-35,   Method: Compositional matrix adjust.
 Identities = 76/135 (56%), Positives = 102/135 (75%), Gaps = 1/135 (0%)

Query: 12  MNIAFFLLPKQEVACVTLDSTLRQTLERMEFHRYTAVPILNRNGEYAGTVTEGDLLWYMK 71
           M IAFFLLPK EV  +  D+T+RQ +ERME+H YTA+PIL++ G+Y GT+TEGDLLW MK
Sbjct: 1   MKIAFFLLPKAEVVYMNEDATMRQVIERMEYHNYTAIPILDKEGKYVGTITEGDLLWKMK 60

Query: 72  DSGGAVTFENASKYLLKDVPLRMNNLPVSIDADMEDLINLAKVQNFVPVVDDMNRFIGIV 131
            +   +TFEN     LK++  +M NLPV IDA+++DL++LA  QNFVPVVDD   FIGI+
Sbjct: 61  HTPN-LTFENTESVSLKEIEQKMVNLPVHIDAEIDDLLSLAIAQNFVPVVDDQGIFIGII 119

Query: 132 RRSQIIEYCEKVVSR 146
           RR  II YC++++ +
Sbjct: 120 RRRDIINYCKELLEK 134


>CAC3008 [R] COG0517 FOG: CBS domain
          Length = 133

 Score = 88.2 bits (217), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 52/130 (40%), Positives = 83/130 (63%), Gaps = 1/130 (0%)

Query: 12  MNIAFFLLPKQEVACVTLDSTLRQTLERMEFHRYTAVPILNRNGEYAGTVTEGDLLWYMK 71
           MNIAFF+ PK++V    L STLRQ  ERM++++   + ILN  GEY G +T+ DL+  +K
Sbjct: 1   MNIAFFITPKKQVVYAKLTSTLRQAFERMKYYKCHELIILNDKGEYVGFITKEDLVKKIK 60

Query: 72  DSGGAVTFENASKYLLKDVPLRMNNLPVSIDADMEDLINLAKVQNFVPVVDDMNRFIGIV 131
           +S   +  ++ +K  + D+   + N P++I+ ++ED+       NFVPV DD N+FIGIV
Sbjct: 61  NSPN-LHLKDFNKVGILDIIKHVINNPININYNVEDISIPMCNTNFVPVADDNNKFIGIV 119

Query: 132 RRSQIIEYCE 141
           ++  I+ Y +
Sbjct: 120 KKDDILNYSK 129


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.320    0.136    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 10,891,745
Number of extensions: 454225
Number of successful extensions: 1464
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 1465
Number of HSP's successfully gapped: 4
Length of query: 152
Length of database: 38,378,431
Length adjustment: 97
Effective length of query: 55
Effective length of database: 27,191,033
Effective search space: 1495506815
Effective search space used: 1495506815
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 111 (47.4 bits)