BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0023.0008.p (312 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA2330 [K] COG0583 Transcriptional regulator 231 9e-61 lin1846 [K] COG0583 Transcriptional regulator 171 2e-42 cynR [K] COG0583 Transcriptional regulator 162 7e-40 BS_gltC [K] COG0583 Transcriptional regulator 158 1e-38 BH2102 [K] COG0583 Transcriptional regulator 147 2e-35 >SA2330 [K] COG0583 Transcriptional regulator Length = 295 Score = 231 bits (590), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 111/293 (37%), Positives = 180/293 (61%), Gaps = 1/293 (0%) Query: 6 MDIRQLQYFVQVARLNSFSRAAESLYISQPTISKMIRNLEVELGADLFYREGKSIRLTDA 65 +DI+ ++YF++V + + A++SLYI+QPTISK I+++E E+G LF R + + LTDA Sbjct: 4 VDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMGTPLFDRSKRHLILTDA 63 Query: 66 GEILLTKAQNIVESFVSLSSELDSLRNLKQGHIRIGLPPMVGASFFPAVIGEFHRRYPDV 125 G+I K++ IV + L SE++ L L+ GHI +G+ ++ ++G FH++YP+V Sbjct: 64 GQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMNMKILINILGAFHQQYPNV 123 Query: 126 TIRLHEDGAKKVEDDVETGLLDIGAIVLPVNTAIFHCFTFVEEKLELLVPAGHRLAGRAS 185 T L E+G K +E + +DIG LPV+ IF T +E L L+V HRLA + Sbjct: 124 TYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHIFDYTTLDKEDLRLIVSREHRLAKYET 183 Query: 186 VPLRELAEEEFVLFREDFALHDRIITECVKTGFQPKVVYESSQWDLISRMVEAGMGIALL 245 V L +LA E+F+LF +DF L+D+II GF P V + SQW +I +V +GI++L Sbjct: 184 VKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTVAQISQWHVIEDLVTNELGISIL 243 Query: 246 PETICRDIDRTRISVVSLTEPVIPWQLGMIWRRDRYLSFAAREWIHFAMGVLG 298 P +I ++ + ++ + + + W+LG++W++D+ LS A +WI F LG Sbjct: 244 PTSISEQLN-GDVKLLRIEDAHVHWELGVVWKKDKQLSHATTKWIEFLKDRLG 295 >lin1846 [K] COG0583 Transcriptional regulator Length = 295 Score = 171 bits (432), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 89/279 (31%), Positives = 162/279 (58%), Gaps = 1/279 (0%) Query: 6 MDIRQLQYFVQVARLNSFSRAAESLYISQPTISKMIRNLEVELGADLFYREGKSIRLTDA 65 M++RQL+YF++VAR+ ++A+E+L+++Q +S+ I LE ELG LF R G++++LT Sbjct: 1 MELRQLKYFMEVARVEHMTKASENLHVAQSAVSRQITKLEEELGVPLFDRVGRNMQLTSV 60 Query: 66 GEILLTKAQNIVESFVSLSSELDSLRNLKQGHIRIGLPPMVGASFFPAVIGEFHRRYPDV 125 G+ L++A + + + + +G +R+GLP + P+VI F +YP++ Sbjct: 61 GQDFLSQATIALNELQKAEALVTEYTDPTKGTVRVGLPNSLSTKVLPSVISTFREKYPEI 120 Query: 126 TIRLHEDGAKKVEDDVETGLLDIGAIV-LPVNTAIFHCFTFVEEKLELLVPAGHRLAGRA 184 T + E +++ + + G+LD+ + +P ++ F +EKL+L+VP H LA Sbjct: 121 TYQFMEGTNEELTEMLVNGVLDMTFLSPVPESSEQIEALRFFDEKLKLIVPTSHHLAENF 180 Query: 185 SVPLRELAEEEFVLFREDFALHDRIITECVKTGFQPKVVYESSQWDLISRMVEAGMGIAL 244 +V L+EL+ E+FVL+ EDF L+ + K GF+P++ ++S + I +V AG+GI++ Sbjct: 181 TVSLKELSSEKFVLYPEDFDLYKIVTKAANKKGFEPQIAFQSRDFYTIQGLVGAGLGISI 240 Query: 245 LPETICRDIDRTRISVVSLTEPVIPWQLGMIWRRDRYLS 283 LPE I ++L + + +G+I + R LS Sbjct: 241 LPEMILDGAIFKETKSIALRDKELRRSVGIITTKKRNLS 279 >cynR [K] COG0583 Transcriptional regulator Length = 299 Score = 162 bits (410), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 91/286 (31%), Positives = 152/286 (53%), Gaps = 2/286 (0%) Query: 9 RQLQYFVQVARLNSFSRAAESLYISQPTISKMIRNLEVELGADLFYREGKSIRLTDAGEI 68 R + YF+ VA SF+RAA +L++SQP +S+ IR LE LG LF R G++IRLTDAGE+ Sbjct: 4 RHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDAGEV 63 Query: 69 LLTKAQNIVESFVSLSSELDSLRNLKQGHIRIGLPPMVGASFFPAVIGEFHRRYPDVTIR 128 A ++ + + + +L +G +RI + P + F ++ +F+ RYP +T++ Sbjct: 64 WRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSITLQ 123 Query: 129 LHEDGAKKVEDDVETGLLDIGAIVLPVNTAIFHCFTFVEEKLELLVPAGHRLAGRASVPL 188 L E +K+ED + LD+G PV++ + E L L+V H LA V L Sbjct: 124 LQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAQHHPLAVHEQVAL 183 Query: 189 RELAEEEFVLFREDFALHDRIITECVKTGFQPKVVYESSQWDLISRMVEAGMGIALLPET 248 L +E+ VL +FA ++I C K G P+VV E++ + ++ LLP Sbjct: 184 SRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAA 243 Query: 249 ICRDIDRTRISVVSLTEPVIPWQLGMIWRRDRYLSFAAREWIHFAM 294 I D + +SL P++ ++ R++ + + AA+ ++H A+ Sbjct: 244 IATQHD--GLKAISLAPPLLERTAVLLRRKNSWQTAAAKAFLHMAL 287 >BS_gltC [K] COG0583 Transcriptional regulator Length = 300 Score = 158 bits (399), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 93/290 (32%), Positives = 150/290 (51%), Gaps = 1/290 (0%) Query: 6 MDIRQLQYFVQVARLNSFSRAAESLYISQPTISKMIRNLEVELGADLFYREGKSIRLTDA 65 MD+RQL+YF++VA S AA+ L+++Q IS+ I NLE EL LF REG++I+LT Sbjct: 1 MDVRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNVTLFEREGRNIKLTPI 60 Query: 66 GEILLTKAQNIVESFVSLSSELDSLRNLKQGHIRIGLPPMVGASFFPAVIGEFHRRYPDV 125 G+ L + +++ ++D + +G ++IG P + + P VI F YP V Sbjct: 61 GKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQLLPTVISAFKEEYPHV 120 Query: 126 TIRLHEDGAKKVEDDVETGLLDIGAI-VLPVNTAIFHCFTFVEEKLELLVPAGHRLAGRA 184 L + K + + V +D+ + +P N + EK+ LVP H LA + Sbjct: 121 EFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKILFTEKIYALVPLNHPLAKQK 180 Query: 185 SVPLRELAEEEFVLFREDFALHDRIITECVKTGFQPKVVYESSQWDLISRMVEAGMGIAL 244 +V L +L ++FVLF E F L + I C + GF P V E D I +V AGMG+ L Sbjct: 181 TVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEGEDLDAIKGLVSAGMGVTL 240 Query: 245 LPETICRDIDRTRISVVSLTEPVIPWQLGMIWRRDRYLSFAAREWIHFAM 294 LPE+ + + + P + +G+I ++R L+ +A ++ F + Sbjct: 241 LPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPSANDFYEFVI 290 >BH2102 [K] COG0583 Transcriptional regulator Length = 301 Score = 147 bits (371), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 91/283 (32%), Positives = 148/283 (52%), Gaps = 11/283 (3%) Query: 6 MDIRQLQYFVQVARLNSFSRAAESLYISQPTISKMIRNLEVELGADLFYREGKSIRLTDA 65 M+ RQL YF++VA+ + AA +L+++Q +S+ I NLE ELG DLF R+G+ ++LT Sbjct: 1 MEFRQLTYFMEVAKREHVTEAAAALHVAQSAVSRQIFNLENELGVDLFIRDGRRVKLTPI 60 Query: 66 GEILL---TKAQNIVESFVSLSSELDSLRNLKQGHIRIGLPPMVGASFFPAVIGEFHRRY 122 G++ L T A N+++ E+ + ++G IR+ P + A P VI F +RY Sbjct: 61 GKMFLERITHAMNVID---DAKREVQEYLDPEKGTIRVAFPISLAAYTLPTVIYAFRKRY 117 Query: 123 PDVTIRLHEDGAKKVEDDVETGLLDIGAIVLPV---NTAIFHCFTFVEEKLELLVPAGHR 179 P+ +L + ++ + V G ++ A++ PV I F E+ + LL P H Sbjct: 118 PEAKFQLKQALYHELINGVIKGDYNM-ALIGPVPMDEKKIARKILFTEQVVALL-PLHHP 175 Query: 180 LAGRASVPLRELAEEEFVLFREDFALHDRIITECVKTGFQPKVVYESSQWDLISRMVEAG 239 LA ++ LR+L ++ FVL E F D +I C GF P + +E D + +V AG Sbjct: 176 LAENNAIHLRDLKDDPFVLLPEGFVFRDIVINACSDLGFYPNIAFEGDDIDALKGLVSAG 235 Query: 240 MGIALLPETICRDIDRTRISVVSLTEPVIPWQLGMIWRRDRYL 282 +G+ L+PE D + L EP + +G+I +R L Sbjct: 236 LGVTLMPEVTLVDSTPRSTVKIPLIEPNVTRTVGVITPTERGL 278 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.139 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,766,338 Number of extensions: 961016 Number of successful extensions: 8719 Number of sequences better than 1.0e-05: 1546 Number of HSP's gapped: 5883 Number of HSP's successfully gapped: 1546 Length of query: 312 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 206 Effective length of database: 26,153,027 Effective search space: 5387523562 Effective search space used: 5387523562 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 116 (49.3 bits)