BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0004.p (398 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2213 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 206 4e-53 Z4489 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 202 7e-52 ECs4015 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 202 8e-52 YPO0838 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 183 5e-46 lin0955 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 175 1e-43 >lin2213 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase Length = 380 Score = 206 bits (525), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 117/352 (33%), Positives = 192/352 (54%), Gaps = 11/352 (3%) Query: 42 LPEAYT--QWPAGNEKTGGGLLIPXXXXXXXXXXXXXXXMYADAEALTAITRYHASQGXX 99 +PE Y+ Q GN G LLIP M E++ A++ A G Sbjct: 37 IPEKYSTEQIFDGN----GQLLIPGMIDVHIHGAKNYDMMDGSTESIQAVSMACAETGCT 92 Query: 100 XXXXXXXXXGKKDIDRVLSEVHAFRSAPMPYAQLAGVHLEGPFISPKWSGAQNPEHIVPA 159 +D+ +++ + A++AG+HLEGP+++ + G QNP ++ Sbjct: 93 SFLVTSVSSSLEDLIQMIKQTKKVVGKEQG-AKIAGIHLEGPYLNIEKKGMQNPAYLRHP 151 Query: 160 NMEWLEQWETLYPGLIRQVTIAPEGEGALRAVTWLRKHGVTAALGHTNASFEEVIAAADA 219 +++ ++Q GLI+ VTIAPE G + + +L+K GV A+ H+NA++EE A + Sbjct: 152 DLKEMKQIFDEADGLIKMVTIAPELPGGIELIDFLKKRGVVIAIAHSNATYEEAQDAFEK 211 Query: 220 GLNQAVHMFNAMTPLHHRKPGAAGAILFDERIRAEIIADGIHVHPAAISVLARLKKEGNL 279 G H FNAM +HHR PG A L ++ + + I DG+H+HP + ++ ++K + Sbjct: 212 GATHITHCFNAMPAIHHRAPGLVTAALENDAVSVQTIVDGVHLHPGIVRLIHKIKGPDKI 271 Query: 280 LLITDAMSATGLSDGEYTIGDLPVLVRDGVARLKENPEALAGSTLTMIRGFRYLVQEVGL 339 +L TDA+ A G+ DGEY G V V++G+ARL++ LA ST+TM + R L E G+ Sbjct: 272 VLTTDALQAMGVGDGEYIFGGHQVTVKEGIARLQDG--TLASSTVTMNKSLR-LSNEFGI 328 Query: 340 TLEEASRAASLTPAQALGLERTIGTLEAGKRGDILLLDNELNLQEVWINGRK 391 +L+++ + A+ TPA+ LG+++ G +E G D++LLD + + WING K Sbjct: 329 SLQDSIQMATSTPAEILGMKK-FGRIEKGYIADLVLLDEKFEVLTTWINGEK 379 >Z4489 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase Length = 377 Score = 202 bits (514), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 113/262 (43%), Positives = 163/262 (62%), Gaps = 3/262 (1%) Query: 129 PYAQLAGVHLEGPFISPKWSGAQNPEHIVPANMEWLEQWETLYPGLIRQVTIAPEGEGAL 188 P AQ+ G +LEGP+ +P+ GA PE + L+Q + +R V +APE EGAL Sbjct: 115 PGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGAL 174 Query: 189 RAVTWLRKHGVTAALGHTNASFEEVIAAADAGLNQAVHMFNAMTPLHHRKPGAAGAILFD 248 +A+ L++ V LGH+ A++++ AA DAG + VH +N MT LHHR+PG GA L D Sbjct: 175 QAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTD 234 Query: 249 ERIRAEIIADGIHVHPAAISVLARLKKEGNLLLITDAMSATGLSDGEYTIGDLPVLVRDG 308 +R E+IADG HVHPAA+S+ KE ++LITDAM A G+ DG YT+ V + G Sbjct: 235 KRAWLELIADGHHVHPAAMSLCCCCAKE-RIVLITDAMQAAGMPDGRYTLCGEEVQMHGG 293 Query: 309 VARLKENPEALAGSTLTMIRGFRYLVQEVGLTLEEASRAASLTPAQALGLERTIGTLEAG 368 V R LAGSTL++ R +V+ G+T EA ASL PA+ LG++ +G+L+ G Sbjct: 294 VVRTASG--GLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPG 351 Query: 369 KRGDILLLDNELNLQEVWINGR 390 KR ++ LD+ L++Q++WI G+ Sbjct: 352 KRASVVALDSGLHVQQIWIQGQ 373 >ECs4015 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase Length = 384 Score = 202 bits (514), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 113/262 (43%), Positives = 163/262 (62%), Gaps = 3/262 (1%) Query: 129 PYAQLAGVHLEGPFISPKWSGAQNPEHIVPANMEWLEQWETLYPGLIRQVTIAPEGEGAL 188 P AQ+ G +LEGP+ +P+ GA PE + L+Q + +R V +APE EGAL Sbjct: 122 PGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHTLRVVALAPEKEGAL 181 Query: 189 RAVTWLRKHGVTAALGHTNASFEEVIAAADAGLNQAVHMFNAMTPLHHRKPGAAGAILFD 248 +A+ L++ V LGH+ A++++ AA DAG + VH +N MT LHHR+PG GA L D Sbjct: 182 QAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTD 241 Query: 249 ERIRAEIIADGIHVHPAAISVLARLKKEGNLLLITDAMSATGLSDGEYTIGDLPVLVRDG 308 +R E+IADG HVHPAA+S+ KE ++LITDAM A G+ DG YT+ V + G Sbjct: 242 KRAWLELIADGHHVHPAAMSLCCCCAKE-RIVLITDAMQAAGMPDGRYTLCGEEVQMHGG 300 Query: 309 VARLKENPEALAGSTLTMIRGFRYLVQEVGLTLEEASRAASLTPAQALGLERTIGTLEAG 368 V R LAGSTL++ R +V+ G+T EA ASL PA+ LG++ +G+L+ G Sbjct: 301 VVRTASG--GLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLHPARMLGVDGVLGSLKPG 358 Query: 369 KRGDILLLDNELNLQEVWINGR 390 KR ++ LD+ L++Q++WI G+ Sbjct: 359 KRASVVALDSGLHVQQIWIQGQ 380 >YPO0838 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase Length = 388 Score = 183 bits (464), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 113/337 (33%), Positives = 173/337 (51%), Gaps = 8/337 (2%) Query: 58 GGLLIPXXXXXXXXXXXXXXXMYADAEALTAITRYHASQGXXXXXXXXXXXGKKDIDRVL 117 G LIP M A AEAL I R G +DI L Sbjct: 47 GKTLIPGLIDIHIHGRQGADVMDASAEALRTIARALPQTGVVAWVGTTVSAPIQDIFAAL 106 Query: 118 SEVHAFRSAP-----MPYAQLAGVHLEGPFISPKWSGAQNPEHIVPANMEWLEQWETLYP 172 ++V F + P A L G LEGP+ + + G+ +++ + LEQ Sbjct: 107 AQVRDFIADPDNARDTRTATLLGSFLEGPYFTAPFRGSHPEKYLTTPTPQELEQLRHSAG 166 Query: 173 GLIRQVTIAPEGEGALRAVTWLRKHGVTAALGHTNASFEEVIAAADAGLNQAVHMFNAMT 232 + + IAPE AL A+ WL HG+ ++ HT A+FE+V AA G + VH++N M+ Sbjct: 167 NTLLRAAIAPESPEALAAIRWLVNHGIKTSVAHTAANFEQVTAAYQQGADCGVHLYNGMS 226 Query: 233 PLHHRKPGAAGAILFDERIRAEIIADGIHVHPAAISVLARLKKEGNLLLITDAMSATGLS 292 LHHR+PG GA+L+ + + AE+IADGIHVHP +++ R+K + LITD M A GL Sbjct: 227 GLHHREPGCCGAVLYHDML-AELIADGIHVHPVMMNLAYRMKGYRRIALITDCMRAGGLG 285 Query: 293 DGEYTIGDLPVLVRDGVARLKENPEALAGSTLTMIRGFRYLVQEVGLTLEEASRAASLTP 352 +G Y +G + VR G AR + +LAGST ++ + R ++Q + EA + AS P Sbjct: 286 EGRYLLGAQHITVRQGEARTDDG--SLAGSTCSLDQALRNMIQHAQVPEWEAVQMASAVP 343 Query: 353 AQALGLERTIGTLEAGKRGDILLLDNELNLQEVWING 389 A LGL T+G+++ G + +++++++ + I G Sbjct: 344 AAYLGLASTLGSIQMGAQASMVVMESDFTVAATLIKG 380 >lin0955 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase Length = 377 Score = 175 bits (443), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 105/314 (33%), Positives = 171/314 (54%), Gaps = 11/314 (3%) Query: 79 MYADAEALTAITRYHASQGXXXXXXXXXXXGKKDIDRVLSEVHAF-RSAPMPYAQLAGVH 137 M AD EAL ++G ++I++ L ++ ++ P+ + G+H Sbjct: 72 MDADPEALKKQVNGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPV----IGGIH 127 Query: 138 LEGPFISPKWSGAQNPEHIVPANMEWLEQWETLYPGLIRQVTIAPEGEGALRAVTWLRKH 197 LEGPF+S + GAQ E+I ++E ++W + GLI+ VT APE + + + Sbjct: 128 LEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDISGGLIQLVTYAPEHDTSADFENLCFEL 187 Query: 198 GVTAALGHTNASFEEVIAAADAGLNQAVHMFNAMTPLHHRKPGAAGAILFDERIRAEIIA 257 GV ++GH+N E + + A H++NA + HR+PG G +L ++ I AE+I Sbjct: 188 GVVPSIGHSNDVREHLKTSK---ATHATHLYNACHRMTHREPGVPGHVLLEKGINAELIV 244 Query: 258 DGIHVHPAAISVLARLKKEGNLLLITDAMSATGLSDGEYTIGDLPVLVRDGVARLKENPE 317 DGIHVHP + + ++K +L +ITD+M A G+ +G+ +G V+V+D ARL++ Sbjct: 245 DGIHVHPDMVKLAYQMKGPEHLCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDG-- 302 Query: 318 ALAGSTLTMIRGFRYLVQEVGLTLEEASRAASLTPAQALGLERTIGTLEAGKRGDILLLD 377 LAGS LT GFR +++ G T+EEA +S A+ L + G ++AGK D LLD Sbjct: 303 TLAGSVLTYDDGFRNMIKFTGCTVEEAVLMSSGNQAREFNLTQK-GAIQAGKDADFNLLD 361 Query: 378 NELNLQEVWINGRK 391 +LN+ + G+K Sbjct: 362 EDLNITATYSFGKK 375 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 29,234,869 Number of extensions: 1138564 Number of successful extensions: 2373 Number of sequences better than 1.0e-05: 16 Number of HSP's gapped: 2334 Number of HSP's successfully gapped: 16 Length of query: 398 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 289 Effective length of database: 25,807,025 Effective search space: 7458230225 Effective search space used: 7458230225 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)