BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0002.p (292 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0191 [K] COG1737 Transcriptional regulators 182 6e-46 BS_ybbH [K] COG1737 Transcriptional regulators 166 5e-41 BH2675 [K] COG1737 Transcriptional regulators 152 6e-37 PM1714 [K] COG1737 Transcriptional regulators 129 4e-30 YPO3017 [K] COG1737 Transcriptional regulators 125 8e-29 >CAC0191 [K] COG1737 Transcriptional regulators Length = 283 Score = 182 bits (461), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 98/263 (37%), Positives = 151/263 (57%), Gaps = 4/263 (1%) Query: 15 LSQMERKLAERILASPGEIVHMGITELAEQCGISPATITRFCKVLHFKGFPDFKVKLAAE 74 L+ ERK+AE IL + I + I ELA + G S + + R CK+L++KG+ +F++ +A + Sbjct: 15 LNPSERKIAEYILNNSKAISDLSIKELAGKSGSSKSAVVRLCKILNYKGYKEFRIAIAKD 74 Query: 75 IAHSDGSPEGSGSSYQDIVAGNPLSVIVEAMQANHLASIRDTTSLLDLERLQSAIDVLCR 134 + D + Y DI + L I++ + N+ SI +T +L E ++ A + + + Sbjct: 75 TVNVDKEE----NRYTDINPKDDLHTIIKNISYNNKKSIDNTMEVLSEELVEKASEAISK 130 Query: 135 ARRVDMYGMATSSIVAQDFYQKLIRIGVNCTAFADSHMQITSASSLQEGDVAFAVSYSGE 194 A RVD YG+ S IVA D +QK +RI N A D+H+Q+ AS+L++GDVA A+SY+GE Sbjct: 131 AYRVDFYGIGASYIVAMDAFQKFMRINKNVRATPDTHLQVEFASNLKKGDVAVAISYTGE 190 Query: 195 TPETIDXXXXXXXXXXXXXXXXXYGSSSLATLADIPLFSSSLEQGMRRGDMASRIAQLHI 254 T +T + +GS+S++ L DI LF S E R G M+SRIAQL++ Sbjct: 191 TKDTFESIKAAKEAGATTISVTKFGSNSISDLCDINLFVLSPEITFRSGAMSSRIAQLNV 250 Query: 255 IDILFTGMVSTRFGDFIPKLEQS 277 IDILFT + F + LE + Sbjct: 251 IDILFTSVAGRMFEEVKEFLENT 273 >BS_ybbH [K] COG1737 Transcriptional regulators Length = 283 Score = 166 bits (419), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 96/284 (33%), Positives = 155/284 (54%), Gaps = 7/284 (2%) Query: 5 LYALEHEKSKLSQMERKLAERILASPGEIVHMGITELAEQCGISPATITRFCKVLHFKGF 64 L ++ K KL ERKLA+ ILA P + + + E++ S A + R CK L KGF Sbjct: 6 LAIIQSMKHKLPPSERKLADYILAHPHKAIESTVNEISALANSSDAAVIRLCKSLGLKGF 65 Query: 65 PDFKVKLAAEIAHSDGSPEGSGSSYQDIVAGNPLSVIVEAMQANHLASIRDTTSLLDLER 124 D K+++A ++A P G Y+DIV PL I E N + +I+DT+ L+D + Sbjct: 66 QDLKMRVAGDLA----KPTFQG--YRDIVPHEPLPSISEKTAGNAIQAIQDTSDLMDYKE 119 Query: 125 LQSAIDVLCRARRVDMYGMATSSIVAQDFYQKLIRIGVNCTAFADSHMQITSASSLQEGD 184 L+ A+ +L +A V G+ S IVA+D QK +RI TAF D+H+ + ++ + D Sbjct: 120 LERAVSLLLKAHTVHFIGLGASGIVAKDAQQKWLRIHKQATAFTDTHLVASLIANADKDD 179 Query: 185 VAFAVSYSGETPETIDXXXXXXXXXXXXXXXXXYGSSSLATLADIPLFSS-SLEQGMRRG 243 + FA+S+SGET E ++ + +S++ LAD+PL+++ S E +R Sbjct: 180 IVFAISFSGETQEIVELFAMAKEKGITTISLTQFSQTSVSALADVPLYTAHSNEALIRSA 239 Query: 244 DMASRIAQLHIIDILFTGMVSTRFGDFIPKLEQSYLNVQHYRHK 287 +SR+AQL IID+LF GM + ++ ++++ +Q R K Sbjct: 240 ATSSRLAQLFIIDVLFLGMAAEQYETTTGYIDKTRAAIQSMRIK 283 >BH2675 [K] COG1737 Transcriptional regulators Length = 287 Score = 152 bits (384), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 86/257 (33%), Positives = 141/257 (54%), Gaps = 7/257 (2%) Query: 13 SKLSQMERKLAERILASPGEIVHMGITELAEQCGISPATITRFCKVLHFKGFPDFKVKLA 72 S S+ E+++A+ ILA+P +++H I ++AE G++ AT+ RFCK L F+G+ K+ LA Sbjct: 20 SSFSEKEKQVADYILANPNKMIHSTINQVAEDLGVAEATVFRFCKRLGFQGYQAMKIALA 79 Query: 73 AEIAHSDGSPEGSGSSYQDIVAGNPLSVIVEAMQANHLASIRDTTSLLDLERLQSAIDVL 132 +EI +P ++ I + + + + +++ ++ DT +LD+E + A+D L Sbjct: 80 SEIV----TP--IQDIHETIQEDDDEKTVADKVFKSNIRTLEDTMQVLDVESFKRAVDYL 133 Query: 133 CRARRVDMYGMATSSIVAQDFYQKLIRIGVNCTAFADSHMQITSASSLQEGDVAFAVSYS 192 ARR++ YG S ++A D + K +R G+ A+ DSH Q+ SAS L + DVA +S+S Sbjct: 134 LHARRIEFYGNGGSGVIALDAHHKFLRTGIPSAAYHDSHFQVMSASQLTKQDVAVFISHS 193 Query: 193 GETPETIDXXXXXXXXXXXXXXXXXYGSSSLATLADIPLFSSSLEQGMRRGDMASRIAQL 252 G + + YG + L+ DI L++ S E R +ASR+AQL Sbjct: 194 GTNRDLLQALEVAKSHQVKTIGITTYGKTPLSKEVDIALYTVSQETEYRSEALASRLAQL 253 Query: 253 HIIDILFTGMVSTRFGD 269 IID L+ VS R D Sbjct: 254 SIIDALYVN-VSIRRKD 269 >PM1714 [K] COG1737 Transcriptional regulators Length = 288 Score = 129 bits (325), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 79/268 (29%), Positives = 139/268 (51%), Gaps = 5/268 (1%) Query: 15 LSQMERKLAERILASPGEIVHMGITELAEQCGISPATITRFCKVLHFKGFPDFKVKLAAE 74 L++ E+++A ILASP + ++++A+ + AT RFC+ L F+GF DFK++LA E Sbjct: 18 LTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCRTLGFRGFTDFKLELAIE 77 Query: 75 IAHSDGSPEGSGSSYQDIVAGNPLSVIVEAMQANHLASIRDTTSLLDLERLQSAIDVLCR 134 +A + + DI + I +Q I +T +LLD L+ ++ + + Sbjct: 78 LATREKQYHSLLDT--DISPSDDPKNIAAKLQGAVTNVIAETINLLDFNELEKVVNTMMK 135 Query: 135 ARRVDMYGMATSSIVAQDFYQKLIRIGVNCTAFADSHMQITSASSLQEGDVAFAVSYSGE 194 A+R+ ++G+ +S I A+D K +RIG+ + +++H A+ +QEGDV +S+SG Sbjct: 136 AKRIFLFGVGSSGITAEDAKNKFMRIGLQVDSTSNNHFMYMQAALMQEGDVVVGISHSGY 195 Query: 195 TPETIDXXXXXXXXXXXXXXXXXYGSSSLATLADIPLFSSSLEQGMRRGD-MASRIAQLH 253 + E I S + AD L + + QG +GD M ++IAQL Sbjct: 196 SKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGN-RQGQLQGDSMGTKIAQLF 254 Query: 254 IIDILFTGMVSTRFGDFIPKLEQSYLNV 281 ++D+++T +V D K +Q +NV Sbjct: 255 VLDLIYTLIVQAT-EDTATKTKQKTVNV 281 >YPO3017 [K] COG1737 Transcriptional regulators Length = 292 Score = 125 bits (314), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 80/261 (30%), Positives = 136/261 (52%), Gaps = 4/261 (1%) Query: 4 ILYALEHEKSKLSQMERKLAERILASPGEIVHMGITELAEQCGISPATITRFCKVLHFKG 63 IL AL ++ L++ +++A ILA P ++ + I +L+ ATI RFC+ L +KG Sbjct: 13 ILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEATIIRFCRTLGYKG 72 Query: 64 FPDFKVKLAAEIAHSDGSPEGSGSSYQDIVAGNPLSVIVEAMQANHLASIRDTTSLLDLE 123 F DFK+ LA E+A S + D+ G+ I +Q+ + +T +LL +E Sbjct: 73 FQDFKMDLAIEVATRHNSENSLLDA--DVQEGDDTLAIGSKLQSAINNVLSETLNLLSIE 130 Query: 124 RLQSAIDVLCRARRVDMYGMATSSIVAQDFYQKLIRIGVNCTAFADSHMQITSASSLQEG 183 ++ + VL A R+ ++G+ +S I A+D KL+RIG+ A ++H AS + G Sbjct: 131 SVEQVVKVLRPADRICIFGVGSSGITAEDAKGKLMRIGLRVDAATNNHFMYMQASLMNPG 190 Query: 184 DVAFAVSYSGETPETIDXXXXXXXXXXXXXXXXXYGSSSLATLADIPLFSSSLEQGMRRG 243 DVA +S+SG + ET+ S + LAD L + + QG +G Sbjct: 191 DVAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLINGN-RQGQLQG 249 Query: 244 D-MASRIAQLHIIDILFTGMV 263 D + ++IAQL ++D+++ +V Sbjct: 250 DSIGTKIAQLFVLDLIYALLV 270 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.133 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,784,684 Number of extensions: 702361 Number of successful extensions: 1505 Number of sequences better than 1.0e-05: 68 Number of HSP's gapped: 1436 Number of HSP's successfully gapped: 68 Length of query: 292 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 187 Effective length of database: 26,268,361 Effective search space: 4912183507 Effective search space used: 4912183507 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)