BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0019.0006.p (757 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_kinA_3 [T] COG0642 Signal transduction histidine kinase 211 4e-54 BS_kinC_2 [T] COG0642 Signal transduction histidine kinase 187 6e-47 BS_kinB [T] COG0642 Signal transduction histidine kinase 145 2e-34 atoS_3 [T] COG0642 Signal transduction histidine kinase 144 8e-34 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 116 1e-25 >BS_kinA_3 [T] COG0642 Signal transduction histidine kinase Length = 236 Score = 211 bits (536), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 108/234 (46%), Positives = 164/234 (70%), Gaps = 3/234 (1%) Query: 509 VSRDMTERNRMEELLRRSEKLTTVGQLAAGVAHEIRNPLTTLRGFLQLQQEKQILVPLHI 568 + RD++ER + EEL+ +SEKL+ GQLAAG+AHEIRNPLT ++GFLQL + + Sbjct: 3 ILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYF 62 Query: 569 ELMLSELERINMIVSEFLILAKPQ--AVHFQLRDVRLILGDVISLLDSQAHLFGIEFEAR 626 +++ SEL RI +I+SE L+LAKPQ AV L +++ ++G+V +LL++QA+L GI Sbjct: 63 DIVFSELSRIELILSELLMLAKPQQNAVKEYL-NLKKLIGEVSALLETQANLNGIFIRTS 121 Query: 627 FSQQPATVHCEENQLKQVFINIVKNAIEAMPDGGTIILEQQIIDGTVVIVISDEGEGVPE 686 + + ++ ++NQLKQVFIN++KNA+E+MPDGGT+ + + +V + + DEGEG+PE Sbjct: 122 YEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPE 181 Query: 687 EILPKLGEPFFTNKETGTGLGLMVSQRIIQSHKGSLEIHSEYGSGAQVTIKLPE 740 ++L ++GEPF T KE GTGLGLMV+ II++H+G + + S G I P+ Sbjct: 182 KVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPK 235 >BS_kinC_2 [T] COG0642 Signal transduction histidine kinase Length = 248 Score = 187 bits (475), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 103/237 (43%), Positives = 152/237 (64%), Gaps = 9/237 (3%) Query: 512 DMTERNRMEE--------LLRRSEKLTTVGQLAAGVAHEIRNPLTTLRGFLQLQQEKQIL 563 D+TER E+ L R S+KL+ +LAAG+AHE+RNPLT++ GFLQ+ + + Sbjct: 7 DITERKEAEDELIEINERLARESQKLSITSELAAGIAHEVRNPLTSVSGFLQIMKTQYPD 66 Query: 564 VPLHIELMLSELERINMIVSEFLILAKPQAVHFQLRDVRLILGDVISLLDSQAHLFGIEF 623 + +++ SE++RI++++SE L+LAKPQA+ F+ + IL V +LLD+ A L I Sbjct: 67 RKDYFDIIFSEIKRIDLVLSELLLLAKPQAITFKTHQLNEILKQVTTLLDTNAILSNIVI 126 Query: 624 EARFSQQPAT-VHCEENQLKQVFINIVKNAIEAMPDGGTIILEQQIIDGTVVIVISDEGE 682 E F + ++ +ENQLKQVFINI+KN IEAMP GG + + VI + DEG Sbjct: 127 EKNFKETDGCMINGDENQLKQVFINIIKNGIEAMPKGGVVTISTAKTASHAVISVKDEGN 186 Query: 683 GVPEEILPKLGEPFFTNKETGTGLGLMVSQRIIQSHKGSLEIHSEYGSGAQVTIKLP 739 G+P+E L ++G+PF++ KE GTGLGL + RI++ H G L+I SE G G+ + LP Sbjct: 187 GMPQEKLKQIGKPFYSTKEKGTGLGLPICLRILKEHDGELKIESEAGKGSVFQVVLP 243 >BS_kinB [T] COG0642 Signal transduction histidine kinase Length = 429 Score = 145 bits (367), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/243 (36%), Positives = 144/243 (59%), Gaps = 6/243 (2%) Query: 507 VHVSRDMTERNRMEELLRRSEKLTTVGQLAAGVAHEIRNPLTTLRGFLQLQQEKQIL--- 563 +++ + E + L SEK+T V +LAA VAHE+RNPLT +RGF+QL + L Sbjct: 188 IYIIESIAENIALRSQLIHSEKMTIVSELAASVAHEVRNPLTVVRGFVQLLFNDETLQNK 247 Query: 564 -VPLHIELMLSELERINMIVSEFLILAKPQAVHFQLRDVRLILGDVISLLDSQAHLFGIE 622 + +L+LSEL+R I++ +L +AK Q ++ D+ ++ + SL+ S A+ + Sbjct: 248 SSADYKKLVLSELDRAQGIITNYLDMAKQQLYEKEVFDLSALIKETSSLMVSYANYKSVT 307 Query: 623 FEARFSQQPATVHCEENQLKQVFINIVKNAIEAMPDG-GTIILEQQIIDGTVVIVISDEG 681 EA ++ ++ + +LKQ IN++KN+IEA+P G G I + + T++I I+D G Sbjct: 308 VEAE-TEPDLLIYGDATKLKQAVINLMKNSIEAVPHGKGMIHISAKRNGHTIMINITDNG 366 Query: 682 EGVPEEILPKLGEPFFTNKETGTGLGLMVSQRIIQSHKGSLEIHSEYGSGAQVTIKLPEA 741 G+ + + KLGEP+++ K GTGLGL V+ II+ H G++ +S + G VTIKLP Sbjct: 367 VGMTDHQMQKLGEPYYSLKTNGTGLGLTVTFSIIEHHHGTISFNSSFQKGTTVTIKLPAD 426 Query: 742 GEH 744 H Sbjct: 427 LPH 429 >atoS_3 [T] COG0642 Signal transduction histidine kinase Length = 278 Score = 144 bits (362), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 80/232 (34%), Positives = 138/232 (59%), Gaps = 5/232 (2%) Query: 512 DMTERNRMEELLRRSEKLTTVGQLAAGVAHEIRNPLTTLRGFLQLQQEKQILVPLHIE-- 569 D+T R + + ++E+L T+G+L AGVAHE+RNPLT +RG++Q+ ++ Q P+H E Sbjct: 39 DLTARKETQRRMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILRQ-QTSDPIHQEYL 97 Query: 570 -LMLSELERINMIVSEFLILAKPQAVHFQLRDVRLILGDVISLLDSQAHLFGIEFEARFS 628 ++L E++ IN ++ + L ++P+ +Q + ++ + + L+ + ++F + Sbjct: 98 SVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELD 157 Query: 629 QQPATVHCEENQLKQVFINIVKNAIEAMPDGGTI-ILEQQIIDGTVVIVISDEGEGVPEE 687 + + ++ + LKQV +NI+ NA++A+ G I I Q D I I D G G+ Sbjct: 158 NELSPINADRELLKQVLLNILINAVQAISARGKIRIQTWQYSDSQQAISIEDNGCGIDLS 217 Query: 688 ILPKLGEPFFTNKETGTGLGLMVSQRIIQSHKGSLEIHSEYGSGAQVTIKLP 739 + K+ +PFFT K +GTGLGL +SQRII +H+G + + S G GA T+ LP Sbjct: 218 LQKKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILP 269 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 116 bits (291), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 20/261 (7%), Positives = 43/261 (16%), Gaps = 25/261 (9%) Query: 500 DGNPQSFVHVSRDMTERNRMEELLRRSEKLTTVGQLAAGVAHEIRNPLTTLRGFLQL--- 556 G F+ S LLR P + L Sbjct: 28 FGYLPWFLLASVTGLLIWHFWNLLR---------LSWWLWVDRSMTPPPGRGSWEPLLYG 78 Query: 557 --QQEKQILVPLHIELMLSELERINMIVSEFLILAKPQAVHFQLR----DVRLILGDVIS 610 Q + + EL + S + +++ Sbjct: 79 LHQMQLRNKKRR-RELGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPE 137 Query: 611 LLDSQAHLFGIEFEARFSQQPATVHCEENQLKQVFINIVKNAIEAMPDGGTIILEQQIID 670 E + N + ++ + ++ Sbjct: 138 DNGQNILNLLRYPEFTQYLKTRDFSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQM 197 Query: 671 GTVVIVISDEGEGVPEEILPKLGEPFF------TNKETGTGLGLMVSQRIIQSHKGSLEI 724 + + V E+ L G + Q+ + + Sbjct: 198 HQLEGARRNFFANVSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLV 257 Query: 725 HSEYGSGAQVTIKLPEAGEHT 745 E Sbjct: 258 KQLLTLSKIEAAPTHLLNEKV 278 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.133 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 51,499,069 Number of extensions: 2195915 Number of successful extensions: 6546 Number of sequences better than 1.0e-05: 259 Number of HSP's gapped: 6148 Number of HSP's successfully gapped: 261 Length of query: 757 Length of database: 38,378,431 Length adjustment: 114 Effective length of query: 643 Effective length of database: 25,230,355 Effective search space: 16223118265 Effective search space used: 16223118265 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 120 (50.8 bits)