BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0011.p (200 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_phoP [TK] COG0745 Response regulators consisting of a CheY-li... 152 4e-37 BS_yclJ [TK] COG0745 Response regulators consisting of a CheY-li... 149 3e-36 SA1323 [TK] COG0745 Response regulators consisting of a CheY-lik... 148 5e-36 lin2062 [TK] COG0745 Response regulators consisting of a CheY-li... 148 5e-36 BS_resD [TK] COG0745 Response regulators consisting of a CheY-li... 144 9e-35 >BS_phoP [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 152 bits (383), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 0/210 (0%), Positives = 0/210 (0%), Gaps = 12/210 (5%) Query: 3 EVFGASDGIEALRLLEDNGVDLAVIDVMMPNMDGWELCKELRRS-YDIPILMLTAKGETS 61 + + + + + + + + I +L + Sbjct: 28 DDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDK 87 Query: 62 QIVKGFELGTDDYLVKPFEPPVLIARVKALLKRYQISAAQS----------VNVGGLRMN 111 V E + + S S + Sbjct: 88 VEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEV 147 Query: 112 RKTYEVTADQGSITLPXXXXXXXXXXASYPGQTLTRDRLIEEVWGYDFEGNERTLDVHVG 171 K + R + ++ + Sbjct: 148 IKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQ 207 Query: 172 RLRDRFPREDYG-FAIRTVRGLGYRLEVGK 200 + + Y Sbjct: 208 EVITTVRGQGYLF 237 >BS_yclJ [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 74/197 (37%), Positives = 117/197 (59%), Gaps = 7/197 (3%) Query: 7 ASDGIEALRLLEDNGVDLAVIDVMMPNMDGWELCKELRRSYDIPILMLTAKGETSQIVKG 66 DG+E + + DL ++D+M+P+MDG +C+++R + +PI+MLTAK S V G Sbjct: 30 VHDGLEGYQRFTEENWDLIILDIMLPSMDGVTICRKIRETSTVPIIMLTAKDTESDQVIG 89 Query: 67 FELGTDDYLVKPFEPPVLIARVKALLKRYQISAAQSVN-----VGGLRMNRKTYEVTADQ 121 FE+G DDY+ KPF P L+AR+KA+++RY+ + ++ +N+KT EV + Sbjct: 90 FEMGADDYVTKPFSPLTLVARIKAVIRRYKATGKAVIDEDMIETECFTINKKTREVLLNG 149 Query: 122 GSI-TLPXXXXXXXXXXASYPGQTLTRDRLIEEVWGYDFEGNERTLDVHVGRLRDRFPRE 180 + L P Q +R++L+E+VWGY F G+ERT+DVH+ RLR + E Sbjct: 150 EPVENLTPKEFDLLYYLVQNPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRKKLASE 209 Query: 181 DYGFAIRTVRGLGYRLE 197 D F + TV G+GY+ + Sbjct: 210 DKPF-LYTVWGVGYKFD 225 >SA1323 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 241 Score = 148 bits (374), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 78/206 (37%), Positives = 116/206 (56%), Gaps = 10/206 (4%) Query: 3 EVFGASDGIEALRLLEDNGVDLAVIDVMMPNMDGWELCKELRRSYDIPILMLTAKGETSQ 62 E+ AS+G EA L +N ++D+M+P MDG ++ +LR PI+MLTAKGE + Sbjct: 28 EIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETN 87 Query: 63 IVKGFELGTDDYLVKPFEPPVLIARVKALLKRYQISAAQS--------VNVGGLRMNRKT 114 V+GFE G DDY+VKPF P ++ RVKALL+R Q + + + L ++ Sbjct: 88 RVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDA 147 Query: 115 YEVTADQGSITLPXXXXXXXXXXASYPGQTLTRDRLIEEVWGYDFEGNERTLDVHVGRLR 174 + V AD + L A P + R++L++EVW Y+F G+ RT+D HV RLR Sbjct: 148 HRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLR 207 Query: 175 DRFPR--EDYGFAIRTVRGLGYRLEV 198 ++ R + I+TV G+GY+ EV Sbjct: 208 EKLNRVSSEAAHMIQTVWGVGYKFEV 233 >lin2062 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 238 Score = 148 bits (373), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 80/202 (39%), Positives = 120/202 (59%), Gaps = 10/202 (4%) Query: 7 ASDGIEALRLLEDNGVDLAVIDVMMPNMDGWELCKELRRSYDIPILMLTAKGETSQIVKG 66 ASDG +AL + +N ++ ++D+MMP DG E+C+ELR P++MLTAKGE + V+G Sbjct: 34 ASDGDQALNMALNNNYEVILLDLMMPGKDGIEVCRELREYKSTPVVMLTAKGEEANRVQG 93 Query: 67 FELGTDDYLVKPFEPPVLIARVKALLKRYQISAAQS--------VNVGGLRMNRKTYEVT 118 FE+G DDY+VKPF P ++ RVKA+L+R + S+ ++ + L+++ + + V Sbjct: 94 FEVGADDYIVKPFSPREVVLRVKAVLRRAKQSSEEAAGGTPGDIITFPHLKIDNEAHRVI 153 Query: 119 ADQGSITLPXXXXXXXXXXASYPGQTLTRDRLIEEVWGYDFEGNERTLDVHVGRLRDRFP 178 D I L A P + R+ L++EVW Y+F G+ RT+D HV RLR++ Sbjct: 154 VDGKEIGLTPKEYDLLYYLAKSPDKVFDRESLLKEVWRYEFFGDLRTIDTHVKRLREKLH 213 Query: 179 --REDYGFAIRTVRGLGYRLEV 198 ED I TV GLGY+ EV Sbjct: 214 DVSEDAARMIVTVWGLGYKFEV 235 >BS_resD [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 240 Score = 144 bits (363), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 79/203 (38%), Positives = 118/203 (58%), Gaps = 10/203 (4%) Query: 7 ASDGIEALRLLEDNGVDLAVIDVMMPNMDGWELCKELRRSYDIPILMLTAKGETSQIVKG 66 A +G EA+ + DL ++D+MMP DG E+C+++R PI+MLTAKGE + V+G Sbjct: 36 AENGDEAIAKGLEANYDLILLDLMMPGTDGIEVCRQIREKKATPIIMLTAKGEEANRVQG 95 Query: 67 FELGTDDYLVKPFEPPVLIARVKALLKRYQISAAQSVNV--------GGLRMNRKTYEVT 118 FE GTDDY+VKPF P ++ RVKALL+R ++ + N L ++ + VT Sbjct: 96 FEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVT 155 Query: 119 ADQGSITLPXXXXXXXXXXASYPGQTLTRDRLIEEVWGYDFEGNERTLDVHVGRLRDRFP 178 AD ++L A P + R++L++EVW Y+F G+ RT+D HV RLR++ Sbjct: 156 ADGTEVSLTPKVYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLN 215 Query: 179 R--EDYGFAIRTVRGLGYRLEVG 199 + + I TV G+GY+ EVG Sbjct: 216 KVSPEAAKKIVTVWGVGYKFEVG 238 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.140 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,200,335 Number of extensions: 544007 Number of successful extensions: 2141 Number of sequences better than 1.0e-05: 405 Number of HSP's gapped: 1852 Number of HSP's successfully gapped: 407 Length of query: 200 Length of database: 38,378,431 Length adjustment: 101 Effective length of query: 99 Effective length of database: 26,729,697 Effective search space: 2646240003 Effective search space used: 2646240003 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 113 (48.1 bits)