BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0004.0003.p
         (92 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

L10014 [I] COG1577 Mevalonate kinase                                   78   3e-15

>L10014 [I] COG1577 Mevalonate kinase
          Length = 105

 Score = 78.2 bits (191), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 40/81 (49%), Positives = 53/81 (65%)

Query: 1  MRLDKFLKVSRLIKRRTVAKDVSEQGRVLINGRESKPSSTVKIGDEITVQFGQXXXXXXX 60
          MRLDKFLKVSRLIKRR VAK+V+++GR+ ING+ +K SS VK  D I ++FG        
Sbjct: 17 MRLDKFLKVSRLIKRRPVAKEVADKGRIKINGKLAKSSSDVKFNDTIEIRFGNKIVEVRV 76

Query: 61 XXXXXXXRKDEAAGMYTLLRE 81
                 RK++A  MY ++ E
Sbjct: 77 AELKEFTRKEDADKMYEMISE 97


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.315    0.133    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 4,769,791
Number of extensions: 135735
Number of successful extensions: 249
Number of sequences better than 1.0e-05: 1
Number of HSP's gapped: 250
Number of HSP's successfully gapped: 1
Length of query: 92
Length of database: 38,378,431
Length adjustment: 62
Effective length of query: 30
Effective length of database: 31,227,723
Effective search space: 936831690
Effective search space used: 936831690
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 109 (46.6 bits)