BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0008.p (441 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2322 [GE] COG2610 H+/gluconate symporter and related permeases 386 e-107 RSp1189 [GE] COG2610 H+/gluconate symporter and related permeases 369 e-102 YPO3954 [GE] COG2610 H+/gluconate symporter and related permeases 288 1e-77 CAC3605 [GE] COG2610 H+/gluconate symporter and related permeases 285 1e-76 BS_gntP [GE] COG2610 H+/gluconate symporter and related permeases 284 2e-76 >PA2322 [GE] COG2610 H+/gluconate symporter and related permeases Length = 450 Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust. Identities = 210/440 (47%), Positives = 282/440 (64%), Gaps = 2/440 (0%) Query: 1 LLIWTLLVIVFLVMLIARFKWNPFVTXXXXXXXXXXXXXMEYPSLIKSXXXXXXXXXXXX 60 LL+ L+ I+ L++LI RFK +PF+ M ++KS Sbjct: 10 LLLDALVTIIGLIVLITRFKVHPFIALIIAAGFLGLTSGMPVEKIVKSFQDGFGGVLGFV 69 Query: 61 XXXXXXXXMLGKMMAESGGAERIADTLVDRFGEKRVHYAMMLVGFVVGIPVFFEVGLILL 120 MLGK+MA+SGGA++IA TL+ FG++RVH++MML F+VGIP+FFE+G ILL Sbjct: 70 GVILALGTMLGKLMADSGGADQIARTLIRAFGKERVHWSMMLAAFLVGIPLFFEIGFILL 129 Query: 121 IPVVFMVARKTKMPLLQIGIPILAGLSTVHGLVPPHPAPMIAIGAYGANLGKTILYSMIV 180 IP+VF+VAR++ + L++IGIP+LAGLS VHGLVPPHP P++AIG +GA++GKTILY +IV Sbjct: 130 IPLVFIVARRSGVSLIKIGIPLLAGLSAVHGLVPPHPGPLLAIGVFGADIGKTILYGLIV 189 Query: 181 GLPTAIIAGPLFGKFIGKRIRVEPPRELAEQFAAK-SVRELPGFGXXXXXXXXXXXXXXX 239 LPTA IAGPLFG + + I P EL EQ A + ++LP FG Sbjct: 190 ALPTAAIAGPLFGALVSRYIPGTPSAELVEQIAHEPETQDLPSFGVTLATVLLPVFLMLL 249 Query: 240 GSVADIIDPEASSAFTPFAKFIGHEIIALLIAAVFSFFSLGFARGFKKEEISRFTSECLA 299 + AD+ P+ AF + IGH I ALL+A + + ++ G+ARGF ++I R + LA Sbjct: 250 KTFADVAFPDG-HAFRAWMDMIGHPISALLLALLVALYTFGYARGFDSKKILRLLDQSLA 308 Query: 300 PTASXXXXXXXXXAFKQVLIDSGVGGAIAALATQTHVNXXXXXXXXXXXXRVATGSATVA 359 PTA+ FKQ+L+ SGVG I LA ++ R+ATGSATVA Sbjct: 309 PTAAIVMIIGAGGGFKQMLVASGVGDVIGHLAVNAQISPILLAWLVAAVIRIATGSATVA 368 Query: 360 MTTAAGIIAPVLAVTPGVNIELAVLATGAGSLVLSHVNDAGFWMIKEFFGMSVVQTLKSW 419 T AGI+ PV+ + PGVN EL VLATGAGSL+LSHVNDAGFW++K++F MSV +T K+W Sbjct: 369 TITGAGIVVPVIDLIPGVNRELLVLATGAGSLILSHVNDAGFWLVKQYFNMSVSETFKTW 428 Query: 420 TVMETILSVVGLTFIMILSI 439 T METILSVVGL FI++LS+ Sbjct: 429 TAMETILSVVGLVFILLLSL 448 >RSp1189 [GE] COG2610 H+/gluconate symporter and related permeases Length = 450 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 201/419 (47%), Positives = 264/419 (63%), Gaps = 3/419 (0%) Query: 13 VMLIARFKWNPFVTXXXXXXXXXXXXXMEYPSLIKSXXXXXXXXXXXXXXXXXXXXMLGK 72 + LIA K NPFVT M +++K+ MLGK Sbjct: 21 IYLIAVRKLNPFVTLIVVSLVLGVAVGMPMGNIVKAFETGVGNTLGHIALVVGLGTMLGK 80 Query: 73 MMAESGGAERIADTLVDRFGEKRVHYAMMLVGFVVGIPVFFEVGLILLIPVVFMVARKTK 132 MMAESGGAERIA TL+ FGEK H+AMM+V F++G+PVFFEVG +LLIP+ F VA++T Sbjct: 81 MMAESGGAERIARTLIRAFGEKNAHWAMMVVAFIIGLPVFFEVGFVLLIPIAFNVAKRTG 140 Query: 133 MPLLQIGIPILAGLSTVHGLVPPHPAPMIAIGAYGANLGKTILYSMIVGLPTAIIAGPLF 192 P+L +G+P++AGLS VHGL+PPHPA ++A+ AY A++GKTILY++IVGLPTAI+AGPLF Sbjct: 141 TPILMVGLPMVAGLSVVHGLIPPHPAALLAVTAYQADIGKTILYALIVGLPTAILAGPLF 200 Query: 193 GKFIGKRIRVEPPRELAEQFA-AKSVRELPGFGXXXXXXXXXXXXXXXGSVADIIDPEAS 251 I + ++ +P L +QF A S RELP FG GS AD++ S Sbjct: 201 AMLISRHVKPDPDNPLEKQFVEADSSRELPPFGITLFTILLPVVLMLIGSWADLLAAPKS 260 Query: 252 SAFTPFAKFIGHEIIALLIAAVFSFFSLGFARGFKKEEISRFTSECLAPTASXXXXXXXX 311 A K G+ ++ALLIAA+ SF++ G ARGF +E I +FT+ECLAP A+ Sbjct: 261 LA-NDLLKLAGNSVMALLIAALVSFYTFGRARGFSREAILKFTNECLAPIATITLVVGAG 319 Query: 312 XAFKQVLIDSGVGGAIAALATQTHVNXXXXXXXXXXXXRVATGSATVAMTTAAGII-APV 370 F Q+L DSGV AI A+A ++ R+ATGSATVAMTTA GI+ Sbjct: 320 GGFGQILRDSGVSKAIVAVAMGASLSPLLLGWVVAVMIRIATGSATVAMTTACGIVAPIA 379 Query: 371 LAVTPGVNIELAVLATGAGSLVLSHVNDAGFWMIKEFFGMSVVQTLKSWTVMETILSVV 429 A V EL VLATGAGSL+LSHVND GFW++KE+F ++V QT ++WTV+ETI+S+V Sbjct: 380 AASGAAVRPELMVLATGAGSLILSHVNDGGFWLVKEYFNLTVPQTFQTWTVLETIISIV 438 >YPO3954 [GE] COG2610 H+/gluconate symporter and related permeases Length = 438 Score = 288 bits (737), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 157/433 (36%), Positives = 247/433 (57%), Gaps = 4/433 (0%) Query: 9 IVFLVMLIARFKWNPFVTXXXXXXXXXXXXXMEYPSLIKSXXXXXXXXXXXXXXXXXXXX 68 + L++L+ R+K N F++ M ++ S Sbjct: 10 VAMLLLLMIRYKLNGFISLILVALAVGIMQGMPIDKVVGSIKAGVGGTLGSLALIMGFGA 69 Query: 69 MLGKMMAESGGAERIADTLVDRFGEKRVHYAMMLVGFVVGIPVFFEVGLILLIPVVFMVA 128 MLGK++A+ GGA+RIA TL+++FG+K + +A++L GF VG +F+EVG +LL+P+VF +A Sbjct: 70 MLGKLLADCGGAQRIATTLIEKFGQKHIQWAVVLTGFTVGFALFYEVGFVLLLPLVFSIA 129 Query: 129 RKTKMPLLQIGIPILAGLSTVHGLVPPHPAPMIAIGAYGANLGKTILYSMIVGLPTAIIA 188 ++PLL +G+P+ A LS HG +PPHP P + A++GKT+LY ++ +PT I+A Sbjct: 130 ASARIPLLYVGVPMAAALSVTHGFLPPHPGPTAIATIFNADMGKTLLYGTLLAIPTVILA 189 Query: 189 GPLFGKFIGKRIRVEPPRELAEQFAAKSVRELPGFGXXXXXXXXXXXXXXXGSVADIIDP 248 GP++ +F+ K I P L + +E+P FG +VA++I P Sbjct: 190 GPVYARFL-KGIDKPVPEGLYNP-KIFTDKEMPSFGVSVSTALVPVILMALRAVAEMILP 247 Query: 249 EASSAFTPFAKFIGHEIIALLIAAVFSFFSLGFARGFKKEEISRFTSECLAPTASXXXXX 308 + S P+A+F G +IA LIA + + F+ G RG E + S+ + A Sbjct: 248 KGHS-LLPYAEFFGDPVIATLIAVLIAIFTFGLNRGRSVESVMETLSDSIKIIAMMLLVI 306 Query: 309 XXXXAFKQVLIDSGVGGAIAALATQTHVNXXXXXXXXXXXXRVATGSATVAMTTAAGIIA 368 AFKQVL+DSG+ IA + + + R+A GSATVA TA GI+A Sbjct: 307 GGGGAFKQVLVDSGIEQYIAGMMGNSGASPILMAWSIAALLRIALGSATVAAITAGGIVA 366 Query: 369 PVLAVTPGVNIELAVLATGAGSLVLSHVNDAGFWMIKEFFGMSVVQTLKSWTVMETILSV 428 P++A T G + EL V+A G+GS++ SHVND GFW+ KE+F +++++T+KSW+V+ETI+SV Sbjct: 367 PLIATT-GASPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLTIMETIKSWSVLETIISV 425 Query: 429 VGLTFIMILSIFV 441 GL ++LS+ + Sbjct: 426 CGLIGCLLLSLVI 438 >CAC3605 [GE] COG2610 H+/gluconate symporter and related permeases Length = 438 Score = 285 bits (729), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 160/433 (36%), Positives = 250/433 (57%), Gaps = 8/433 (1%) Query: 9 IVFLVMLIARFKWNPFVTXXXXXXXXXXXXXMEYPSLIKSXXXXXXXXXXXXXXXXXXXX 68 + L++L+ +FK N F++ M + S Sbjct: 10 VALLLLLMIKFKVNGFISLILVALVVGIAEGMNPAKAVSSIQNGVGSTLSSLALILGFGA 69 Query: 69 MLGKMMAESGGAERIADTLVDRFGEKRVHYAMMLVGFVVGIPVFFEVGLILLIPVVFMVA 128 M GK++A+SG A+RI+ +L+++FG K++ +A++L GF+VGI +F+EVG +LLIP+VF +A Sbjct: 70 MFGKLIADSGAAQRISRSLINKFGVKKIQWAVVLTGFIVGIAMFYEVGFVLLIPLVFTIA 129 Query: 129 RKTKMPLLQIGIPILAGLSTVHGLVPPHPAPMIAIGAYGANLGKTILYSMIVGLPTAIIA 188 T++PLL IG+P+ A LS HG +PPHP P+ YGA++ T++Y +++ +PT I+A Sbjct: 130 EFTELPLLYIGVPMAAALSVTHGFLPPHPGPVAIATIYGASISMTLVYGIVIAIPTVIVA 189 Query: 189 GPLFGKFIGKRIRVEPPRELAEQFAAK--SVRELPGFGXXXXXXXXXXXXXXXGSVADII 246 GP+ KF+ KR + + L F K E+P F +V +I Sbjct: 190 GPVLTKFL-KRFDHKSSKNL---FKTKVFDEDEMPSFSLSVLTAIVPPILMAFSAVCEIT 245 Query: 247 DPEASSAFTPFAKFIGHEIIALLIAAVFSFFSLGFARGFKKEEISRFTSECLAPTASXXX 306 P+ +S FA+F+G ++A+ I+ + + F+LG RG K EEI R +E + A Sbjct: 246 LPK-TSPIRHFAEFVGSPMMAMFISIIVAIFTLGIMRGKKMEEIMRTLAEAASSIAMILL 304 Query: 307 XXXXXXAFKQVLIDSGVGGAIAALATQTHVNXXXXXXXXXXXXRVATGSATVAMTTAAGI 366 AFKQVLIDSGVG IA++ ++++ R++ GSATV+ T AGI Sbjct: 305 IVAGGGAFKQVLIDSGVGKYIASIMVGSNISPLILAWAIAAILRLSLGSATVSAMTTAGI 364 Query: 367 IAPVLAVTPGVNIELAVLATGAGSLVLSHVNDAGFWMIKEFFGMSVVQTLKSWTVMETIL 426 + P++ T N L VLATGAGSL+ SHVND GFWM KE+FG+S+ +T+ SW+ +ETI+ Sbjct: 365 VLPLIPSTHA-NPALMVLATGAGSLIFSHVNDPGFWMFKEYFGLSIGETMASWSTLETII 423 Query: 427 SVVGLTFIMILSI 439 S++GL ++ L++ Sbjct: 424 SIMGLIGVLALNM 436 >BS_gntP [GE] COG2610 H+/gluconate symporter and related permeases Length = 448 Score = 284 bits (727), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 165/447 (36%), Positives = 251/447 (56%), Gaps = 8/447 (1%) Query: 2 LIWTLLVIVFLVMLIARFKWNPFVTXXXXXXXXXXXXXMEYPSLIKSXXXXXXXXXXXXX 61 LI L I+ L+ LI K N F++ M + ++ S Sbjct: 3 LIIVALGILALLFLIMGLKLNTFISLLVVSFGVALALGMPFDKVVSSIEAGIGGTLGHIA 62 Query: 62 XXXXXXXMLGKMMAESGGAERIADTLVDRFGEKRVHYAMMLVGFVVGIPVFFEVGLILLI 121 MLGK++A+SGGA+RIA TLV++FGEK + +A+++ F++GI +FFEVGL+LLI Sbjct: 63 LIFGLGAMLGKLIADSGGAQRIAMTLVNKFGEKNIQWAVVIASFIIGIALFFEVGLVLLI 122 Query: 122 PVVFMVARKTKMPLLQIGIPILAGLSTVHGLVPPHPAPMIAIGAYGANLGKTILYSMIVG 181 P+VF ++R+ K+ +L +GIP++A LS HG +PPHP P G YGAN+G+ +LY IV Sbjct: 123 PIVFAISRELKISILFLGIPMVAALSVTHGFLPPHPGPTAIAGEYGANIGEVLLYGFIVA 182 Query: 182 LPTAIIAGPLFGKFIGKRIRVEPPR--ELAEQFAAK--SVRELPGFGXXXXXXXXXXXXX 237 +PT +IAGPLF KF K + + +A K ++ E PGFG Sbjct: 183 VPTVLIAGPLFTKFAKKIVPASFAKNGNIASLGTQKTFNLEETPGFGISVFTAMLPIIIM 242 Query: 238 XXGSVADIIDPE---ASSAFTPFAKFIGHEIIALLIAAVFSFFSLGFARGFKKEEISRFT 294 ++ D++ A + F + IG+ A++I+ + + +++G R + + Sbjct: 243 SVATIIDLLQETIGFADNGVLAFIRLIGNASTAMIISLLVAVYTMGIKRNIPVKTVMDSC 302 Query: 295 SECLAPTASXXXXXXXXXAFKQVLIDSGVGGAIAALATQTHVNXXXXXXXXXXXXRVATG 354 S ++ AFKQVLI+ GVG +A L T ++ R++ G Sbjct: 303 STAISQIGMMLLIIGGGGAFKQVLINGGVGDYVADLFKGTALSPIILAWLIAAILRISLG 362 Query: 355 SATVAMTTAAGIIAPVLAVTPGVNIELAVLATGAGSLVLSHVNDAGFWMIKEFFGMSVVQ 414 SATVA + G++ P+L + VN+ L VLATGAGS++ SHVNDAGFWM KE+FG+S+ + Sbjct: 363 SATVAALSTTGLVIPLLGHSD-VNLALVVLATGAGSVIASHVNDAGFWMFKEYFGLSMKE 421 Query: 415 TLKSWTVMETILSVVGLTFIMILSIFV 441 T +WT++ETI+SV GL FI++LS+ V Sbjct: 422 TFATWTLLETIISVAGLGFILLLSLVV 448 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.327 0.141 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,824,023 Number of extensions: 950309 Number of successful extensions: 3173 Number of sequences better than 1.0e-05: 42 Number of HSP's gapped: 3056 Number of HSP's successfully gapped: 43 Length of query: 441 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 332 Effective length of database: 25,807,025 Effective search space: 8567932300 Effective search space used: 8567932300 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 117 (49.7 bits)