BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0005.p (166 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3586 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 216 1e-56 BS_yvoF [R] COG0110 Acetyltransferase (isoleucine patch superfam... 214 6e-56 lin2623 [R] COG0110 Acetyltransferase (isoleucine patch superfam... 176 2e-44 SA0717 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) 145 4e-35 VNG1385G [R] COG0110 Acetyltransferase (isoleucine patch superfa... 120 1e-27 >BH3586 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 166 Score = 216 bits (551), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 102/158 (64%), Positives = 130/158 (82%), Gaps = 1/158 (0%) Query: 1 VEGHNSLWYIYRTVSPWKGVRNFIFIQIARYCPILPVKNWIYRNVLGMKVGKHTAFGLMA 60 V+ NSLW IY+TV WK V+NF+ IQ+ARY P + VKNW+YR L M VG+ TAF LM Sbjct: 10 VKHANSLWQIYKTVPFWKVVKNFVVIQLARYTPFVSVKNWLYRTFLKMDVGEKTAFALMV 69 Query: 61 MVDVFFPEKITVGENSVIGYNTTILAHEYLIKEYRLGEVIIGENVLIGANTTILPGVIIG 120 M D+ FPE+I+VG NS+IGYNTTILAHEYLI+EYRLG+VIIG+ V++GANTTILPGV IG Sbjct: 70 MPDIMFPERISVGRNSIIGYNTTILAHEYLIEEYRLGDVIIGDEVMVGANTTILPGVTIG 129 Query: 121 DGAVIAAGSVVHKDVAAGSFVGGNPLRELRPSARNDRD 158 D A+IAAG+VVHK+V G+FVGGNP++ ++ + R+D+D Sbjct: 130 DRAIIAAGTVVHKNVPPGAFVGGNPMQVIKQN-RDDKD 166 >BS_yvoF [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 172 Score = 214 bits (544), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 100/147 (68%), Positives = 123/147 (83%) Query: 1 VEGHNSLWYIYRTVSPWKGVRNFIFIQIARYCPILPVKNWIYRNVLGMKVGKHTAFGLMA 60 V G NSLW++Y+TV K V+NFI IQIARY P + +KNW+YR L MKVGK T+F LM Sbjct: 9 VSGANSLWHVYQTVPFLKVVKNFIVIQIARYTPFIGMKNWLYRTFLRMKVGKQTSFALMV 68 Query: 61 MVDVFFPEKITVGENSVIGYNTTILAHEYLIKEYRLGEVIIGENVLIGANTTILPGVIIG 120 M D+ FPEKI+VG N++IGYNTTILAHEYLI EYR+G+V+IG+ V+IGANTTILPGV IG Sbjct: 69 MPDIMFPEKISVGTNTIIGYNTTILAHEYLIHEYRIGKVLIGDEVMIGANTTILPGVKIG 128 Query: 121 DGAVIAAGSVVHKDVAAGSFVGGNPLR 147 DGAV++AG++VHKDV G+FVGGNP+R Sbjct: 129 DGAVVSAGTLVHKDVPDGAFVGGNPMR 155 >lin2623 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 301 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 2/145 (1%), Positives = 15/145 (10%) Query: 2 EGHNSLWYIYRTVSPWKGVRNFIFIQIARYCPILPVKNWIYRNVLGMKVGKHTAFGLMAM 61 T+ + + + Sbjct: 12 AIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEK 71 Query: 62 VDVFFPEKITVGENSVIGYNTTILAHEYLIKEYRLGEVIIGENVLIGANTTILPGVIIGD 121 + + + + + + + Sbjct: 72 RAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQE 131 Query: 122 GAVIAAGSVVHKDVAAGSFVGGNPL 146 A + + Sbjct: 132 KADLLPHLQFLASQMNFLDIVPISA 156 >SA0717 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 161 Score = 145 bits (365), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 68/142 (47%), Positives = 93/142 (65%) Query: 5 NSLWYIYRTVSPWKGVRNFIFIQIARYCPILPVKNWIYRNVLGMKVGKHTAFGLMAMVDV 64 N LW +YR V K +N I I+ +++ P + +K IY+ +L + +G ++ M+D+ Sbjct: 13 NPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDI 72 Query: 65 FFPEKITVGENSVIGYNTTILAHEYLIKEYRLGEVIIGENVLIGANTTILPGVIIGDGAV 124 F+PE IT+G NSVIGYN TIL HE L+ E+R G V IG N LIGAN TILPG+ IGD Sbjct: 73 FYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVK 132 Query: 125 IAAGSVVHKDVAAGSFVGGNPL 146 +AAG+VV KD+ F GNP+ Sbjct: 133 VAAGTVVSKDIPDNGFAYGNPM 154 >VNG1385G [R] COG0110 Acetyltransferase (isoleucine patch superfamily) Length = 172 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 61/141 (43%), Positives = 86/141 (60%), Gaps = 1/141 (0%) Query: 5 NSLWYIYRTVSPWKGVRNFIFIQIARYCPILPVKNWIYRNVLGMKVGKHTAFGLMAMVDV 64 NSLW P + N++ I +AR P L KNW+ + G+ VG A+GL + DV Sbjct: 27 NSLWRWTDAKHPLRVALNYVVIVLARISPSLHAKNWLLARI-GVTVGDGVAWGLESTPDV 85 Query: 65 FFPEKITVGENSVIGYNTTILAHEYLIKEYRLGEVIIGENVLIGANTTILPGVIIGDGAV 124 F+PE +TVG++++IGY+ T+L HE+L EYR G V++ + +IGA +LPGV IG A Sbjct: 86 FWPELVTVGDDAIIGYDATLLCHEFLHDEYRTGAVVVEDRAMIGAGAVVLPGVTIGADAQ 145 Query: 125 IAAGSVVHKDVAAGSFVGGNP 145 +AA S+V DV G V G P Sbjct: 146 VAANSLVTADVPPGETVAGVP 166 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.141 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 13,773,327 Number of extensions: 597393 Number of successful extensions: 1447 Number of sequences better than 1.0e-05: 77 Number of HSP's gapped: 1402 Number of HSP's successfully gapped: 77 Length of query: 166 Length of database: 38,378,431 Length adjustment: 98 Effective length of query: 68 Effective length of database: 27,075,699 Effective search space: 1841147532 Effective search space used: 1841147532 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 112 (47.8 bits)