BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.5548.p (68 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SP1263_1 [L] COG0550 Topoisomerase IA Spn Streptococcus pneumoni... 27 8.2 >SP1263_1 [L] COG0550 Topoisomerase IA Spn Streptococcus pneumoniae TIGR4 Length = 553 Score = 27.3 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 18/33 (54%) Query: 19 SKCSTAGPAVDLHRAVAQAAVFETPSSTGLHIE 51 SK A A D H A+ ++VF TP S +++ Sbjct: 341 SKVKNASGAQDAHEAIRPSSVFNTPESIAKYLD 373