BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4624.p (475 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 449 e-126 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 436 e-122 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 436 e-122 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 435 e-122 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 420 e-117 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 449 bits (1154), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/448 (51%), Positives = 314/448 (70%), Gaps = 2/448 (0%) Query: 22 EGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIVTAYQLAMMV 81 +GLP +R AIL + + + +A LD IAN ALP +A DL T+PA S+W+V AYQLA+ + Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 82 ALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLGGAGIMSVNT 141 +LL +A+LG+I+GYRR+Y GL++F+ SL CA++ SL TL AR LQG G A +MSVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVIL 201 ALIR IYP LGRG+G+NTLIVA++ GPS+A+ +L++A W WLFA+NVP+G+ A L Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 202 ALPSLP--HTKLSSHAFDLRSAVLNAAAFGLLILAIGEGAHQAELKVVGLELAAAIVCGL 259 + LP +TK + + FD+ S VLNA FGLLI AI + V+ ++ A ++ G Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 260 LLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 ++R+L+ P+LPVDL R P+F LS T++ SFAAQ LA VSLPFF LGR +V Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 320 GLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAAPSVWEISWR 379 GLL+TPWP+A ++APIAGRL + Y G+LGG+GLA+ GL + +PA PS +I WR Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWR 366 Query: 380 MLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSETH 439 M+LCG GFG FQ+PN ++++AP HRSGGASG++ TARLLGQ+ GAALVAL FN+ T+ Sbjct: 367 MILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMFNMFSTN 426 Query: 440 GSRLALGFGAAFAGVACIASFLRLLTRN 467 G+ +L FA +A + S LR+ ++ Sbjct: 427 GTHASLILAGCFASIAALVSLLRVTQKS 454 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 228/435 (52%), Positives = 305/435 (70%), Gaps = 4/435 (0%) Query: 13 PQPHIVIAGEGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIV 72 P P + +GLP +R AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V Sbjct: 37 PMPKV--QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVV 94 Query: 73 TAYQLAMMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLG 132 AYQ+A++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG G Sbjct: 95 NAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFG 154 Query: 133 GAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNV 192 GA +MSVNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NV Sbjct: 155 GAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINV 214 Query: 193 PLGVAAVILALPSLP--HTKLSSHAFDLRSAVLNAAAFGLLILAIGEGAHQAELKVVGLE 250 PLG+ A++LA+ LP ++ S FDL SAV+NA FGLLI A+ A L ++ E Sbjct: 215 PLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAE 274 Query: 251 LAAAIVCGLLLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHH 310 L +V G+ ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ Sbjct: 275 LVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQT 334 Query: 311 DLGRSQVEIGLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAA 370 LGRS+VE GLL+TPWP+A +MAP+AG L + G+LG +GL I+ GL + +PA+ Sbjct: 335 VLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPAS 394 Query: 371 PSVWEISWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVA 430 P+ I W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVA Sbjct: 395 PADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVA 454 Query: 431 LCFNLSETHGSRLAL 445 L N +G+ ++L Sbjct: 455 LMLNQFGDNGTHVSL 469 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 228/435 (52%), Positives = 305/435 (70%), Gaps = 4/435 (0%) Query: 13 PQPHIVIAGEGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIV 72 P P + +GLP +R AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V Sbjct: 37 PMPKV--QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVV 94 Query: 73 TAYQLAMMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLG 132 AYQ+A++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG G Sbjct: 95 NAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFG 154 Query: 133 GAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNV 192 GA +MSVNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NV Sbjct: 155 GAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINV 214 Query: 193 PLGVAAVILALPSLP--HTKLSSHAFDLRSAVLNAAAFGLLILAIGEGAHQAELKVVGLE 250 PLG+ A++LA+ LP ++ S FDL SAV+NA FGLLI A+ A L ++ E Sbjct: 215 PLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAE 274 Query: 251 LAAAIVCGLLLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHH 310 L +V G+ ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ Sbjct: 275 LVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQT 334 Query: 311 DLGRSQVEIGLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAA 370 LGRS+VE GLL+TPWP+A +MAP+AG L + G+LG +GL I+ GL + +PA+ Sbjct: 335 VLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPAS 394 Query: 371 PSVWEISWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVA 430 P+ I W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVA Sbjct: 395 PADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVA 454 Query: 431 LCFNLSETHGSRLAL 445 L N +G+ ++L Sbjct: 455 LMLNQFGDNGTHVSL 469 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 435 bits (1119), Expect = e-122, Method: Compositional matrix adjust. Identities = 228/435 (52%), Positives = 305/435 (70%), Gaps = 4/435 (0%) Query: 13 PQPHIVIAGEGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIV 72 P P + +GLP +R AIL + I + +A LD AIAN ALP +A DL TPA+S+W+V Sbjct: 37 PMPKV--QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVV 94 Query: 73 TAYQLAMMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLG 132 AYQ+A++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG G Sbjct: 95 NAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFG 154 Query: 133 GAGIMSVNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNV 192 GA +MSVNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NV Sbjct: 155 GAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINV 214 Query: 193 PLGVAAVILALPSLP--HTKLSSHAFDLRSAVLNAAAFGLLILAIGEGAHQAELKVVGLE 250 PLG+ A++LA+ LP ++ S FDL SAV+NA FGLLI A+ A L ++ E Sbjct: 215 PLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAE 274 Query: 251 LAAAIVCGLLLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHH 310 L +V G+ ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ Sbjct: 275 LVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQT 334 Query: 311 DLGRSQVEIGLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAA 370 LGRS+VE GLL+TPWP+A +MAP+AG L + G+LG +GL I+ GL + +PA+ Sbjct: 335 VLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPAS 394 Query: 371 PSVWEISWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVA 430 P+ I W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVA Sbjct: 395 PADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVA 454 Query: 431 LCFNLSETHGSRLAL 445 L N +G+ ++L Sbjct: 455 LMLNQFGDNGTHVSL 469 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 420 bits (1079), Expect = e-117, Method: Compositional matrix adjust. Identities = 225/425 (52%), Positives = 297/425 (69%), Gaps = 2/425 (0%) Query: 22 EGLPPERRGRAILALGIAVGLATLDTAIANTALPAMALDLKTTPAASVWIVTAYQLAMMV 81 +GLP +R AIL + I + +A LD AIAN ALP +A DL +PA+S+WIV AYQ+A++V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 82 ALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVIARFLQGLGGAGIMSVNT 141 +LL L+ LG++ GY RIY GLV+F +SL CA++ SL L +AR QG GGA +MSVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVIL 201 ALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+I+ W WLF +NVPLG+ A+IL Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 202 ALPSLPHT--KLSSHAFDLRSAVLNAAAFGLLILAIGEGAHQAELKVVGLELAAAIVCGL 259 A+ LP + FDL SAV+NA FGLLI A+ A L ++G EL +V G Sbjct: 187 AIRFLPANIAHDTKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVVVGF 246 Query: 260 LLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 ++R+LS P P+LP+DL R P+F+LS T++CSF AQ LA VSLPF+ LGRS+VE Sbjct: 247 FFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRSEVET 306 Query: 320 GLLMTPWPVAVAIMAPIAGRLSDHYPVGILGGVGLAILCVGLLWMTFMPAAPSVWEISWR 379 GLL+TPWP+A +MAP+AG L + G+LG +G+ I+ GL + +PA+PS I W Sbjct: 307 GLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPSDLNIIWP 366 Query: 380 MLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSETH 439 M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 367 MILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSTGAALVALMLNQFGDS 426 Query: 440 GSRLA 444 G+ L+ Sbjct: 427 GTHLS 431