BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4591.p (304 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM4195 [R] COG0385 Predicted Na+-dependent transporter Sty Salm... 387 e-107 SA2112 [R] COG0385 Predicted Na+-dependent transporter Sau Staph... 253 5e-67 BH0858 [R] COG0385 Predicted Na+-dependent transporter Bha Bacil... 249 8e-66 PA3264 [R] COG0385 Predicted Na+-dependent transporter Pae Pseud... 246 6e-65 BS_yocS [R] COG0385 Predicted Na+-dependent transporter Bsu Baci... 241 2e-63 >STM4195 [R] COG0385 Predicted Na+-dependent transporter Sty Salmonella typhimurium LT2 Length = 313 Score = 387 bits (995), Expect = e-107, Method: Compositional matrix adjust. Identities = 217/301 (72%), Positives = 253/301 (84%) Query: 1 MLATITRLFPVWALLLSAAAYFSPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKRIIKR 60 MLA ITRLFP+WALLLS AY++P TFTP+G ++ LL LIM MGV L VDDFKR++ R Sbjct: 1 MLAVITRLFPLWALLLSLTAYYTPSTFTPVGPWVATLLMLIMFGMGVHLNVDDFKRVLSR 60 Query: 61 PAPVAAGIILHYLVMPLAAWIIAKVLHMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVA 120 PAPVAAGI LHYLVMPLAAW++A + MPPDL+AGMVLVGSVASGTASNVMIYL++GDVA Sbjct: 61 PAPVAAGIFLHYLVMPLAAWLLALLFKMPPDLSAGMVLVGSVASGTASNVMIYLAKGDVA 120 Query: 121 LSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVLPIAVGLVLNLFAGN 180 LSVTIS++S LV V ATPLLT LYVDA I D ML+SI+QIVV+PI +GLV++ Sbjct: 121 LSVTISSVSTLVGVVATPLLTRLYVDAHIQVDVMGMLLSILQIVVIPITLGLVIHHLFPR 180 Query: 181 LIRRIEPYLSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYWGGRL 240 +++ ++PYL SMV IL II+AVVAGS + IASVG +V++ VILHN LGLLGGYWGGRL Sbjct: 181 VVKVVKPYLPAFSMVCILAIISAVVAGSASHIASVGFMVIIAVILHNTLGLLGGYWGGRL 240 Query: 241 LGFDEAVCRTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGYWRGR 300 GFDE+ CRTLAIEVGMQNSGLAAALGK+YF P+AALPGALFSVWHNLSGSLLAGYW G+ Sbjct: 241 FGFDESTCRTLAIEVGMQNSGLAAALGKIYFGPLAALPGALFSVWHNLSGSLLAGYWSGK 300 Query: 301 P 301 P Sbjct: 301 P 301 >SA2112 [R] COG0385 Predicted Na+-dependent transporter Sau Staphylococcus aureus N315 Length = 305 Score = 253 bits (645), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 131/295 (44%), Positives = 195/295 (66%) Query: 6 TRLFPVWALLLSAAAYFSPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKRIIKRPAPVA 65 T+ F VW L+ + + P +GK++ LL ++ML MG+T+T +DFK + K P V Sbjct: 10 TKSFLVWMLVAAVIGFIFPQHVATLGKWVPYLLGIVMLGMGLTITPNDFKMVFKAPRAVI 69 Query: 66 AGIILHYLVMPLAAWIIAKVLHMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVALSVTI 125 G+ L + +MP A+IIAK H+PPD+ G++LVG GT+SNVM YL++ +VALSV+I Sbjct: 70 IGVCLQFSIMPTLAFIIAKSFHLPPDIAVGVILVGCCPGGTSSNVMSYLAKANVALSVSI 129 Query: 126 STLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVLPIAVGLVLNLFAGNLIRRI 185 +T+S L++ F TP L L+ + + +ML S+VQ+V++PIA+G+VL + + + Sbjct: 130 TTVSTLLAPFVTPALIYLFANEWLEVSFLSMLWSVVQVVLIPIALGIVLQIINRKIAEKA 189 Query: 186 EPYLSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYWGGRLLGFDE 245 L ++S+VAI LI+A VV GS+ I + GL++ + VILHN LG GYW RLL D Sbjct: 190 STALPIISVVAISLILAIVVGGSKHQILTTGLLIFLVVILHNVLGYTIGYWLARLLKLDR 249 Query: 246 AVCRTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGYWRGR 300 + ++IEVGMQNSGLA +L L+F P+AA+PGA+FS HN++G +LA YW + Sbjct: 250 QDQKAVSIEVGMQNSGLAVSLAALHFNPIAAVPGAVFSFIHNITGPILAKYWSKK 304 >BH0858 [R] COG0385 Predicted Na+-dependent transporter Bha Bacillus halodurans Length = 323 Score = 249 bits (635), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 130/301 (43%), Positives = 204/301 (67%), Gaps = 4/301 (1%) Query: 1 MLATITRLFPVW----ALLLSAAAYFSPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKR 56 MLA +++ F + +++S A+ SP FT I +IT LL +IM MG+TL + DF+ Sbjct: 3 MLAKVSQFFSKYFAFFVIIISFVAFLSPDHFTWITPHITILLGVIMFGMGLTLKLSDFRI 62 Query: 57 IIKRPAPVAAGIILHYLVMPLAAWIIAKVLHMPPDLTAGMVLVGSVASGTASNVMIYLSR 116 ++++P PV G++ +++MPL A+ +A ++PP+L AG+VLVG+ GTASNVM+YL++ Sbjct: 63 VLQKPIPVLVGVLAQFVIMPLVAFALAYAFNLPPELAAGLVLVGACPGGTASNVMVYLAK 122 Query: 117 GDVALSVTISTLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVLPIAVGLVLNL 176 G+VA SV ++++S +++ TP + L + DA AM +SI+Q++++PIA+GL + Sbjct: 123 GNVAASVAMTSVSTMLAPIVTPFILLLLAGQWLPIDAKAMFVSILQMIIVPIALGLFVRK 182 Query: 177 FAGNLIRRIEPYLSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYW 236 A N + + L LVS+VAI+ I++AVV +QA++ S ++ + V+LHN GLL GY Sbjct: 183 MAPNAVDKSTAVLPLVSIVAIMAIVSAVVGANQANLMSGAALLFLAVMLHNVFGLLLGYL 242 Query: 237 GGRLLGFDEAVCRTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGY 296 + +G DE+ R ++IEVGMQNSGL AAL +F+P+AALP A+FSVWHN+SG +L Sbjct: 243 TAKFVGLDESTRRAISIEVGMQNSGLGAALAGNHFSPLAALPSAIFSVWHNISGPVLVSI 302 Query: 297 W 297 W Sbjct: 303 W 303 >PA3264 [R] COG0385 Predicted Na+-dependent transporter Pae Pseudomonas aeruginosa Length = 311 Score = 246 bits (627), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 140/290 (48%), Positives = 195/290 (67%) Query: 9 FPVWALLLSAAAYFSPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKRIIKRPAPVAAGI 68 FP W LL + A+F P F P+ I LL L+M MG+TL +DF+ + + P V G+ Sbjct: 15 FPFWVLLFAILAFFRPAWFLPLTAAIAPLLGLVMFGMGLTLKGEDFREVARHPIRVLIGV 74 Query: 69 ILHYLVMPLAAWIIAKVLHMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVALSVTISTL 128 + +++MP AW++ ++L +P ++ G++LVG GTASNVM +LSRGDVALSV I+++ Sbjct: 75 LAQFVIMPGLAWLLCRLLQLPAEIAVGVILVGCCPGGTASNVMTWLSRGDVALSVAITSV 134 Query: 129 SALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVLPIAVGLVLNLFAGNLIRRIEPY 188 + L++ TP L L A + AM +SI+Q+V++PIA+GL+ G R++ Sbjct: 135 TTLLAPLVTPALVWLLASAWLPVSFAAMFLSILQVVLVPIALGLLAQRLLGERTRQVAEV 194 Query: 189 LSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYWGGRLLGFDEAVC 248 L LVS+ +I++IIAAVVA SQA IA GL+++ V+LHNG GLL GY G+L G A Sbjct: 195 LPLVSVFSIVVIIAAVVAASQARIAESGLLIMAVVMLHNGFGLLLGYLTGKLTGMPLAQR 254 Query: 249 RTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGYWR 298 + LAIEVGMQNSGL AAL +F+P+AA+P ALFSVWHNLSGSLLA +R Sbjct: 255 KALAIEVGMQNSGLGAALANAHFSPLAAVPSALFSVWHNLSGSLLAALFR 304 >BS_yocS [R] COG0385 Predicted Na+-dependent transporter Bsu Bacillus subtilis Length = 321 Score = 241 bits (615), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 124/298 (41%), Positives = 192/298 (64%) Query: 7 RLFPVWALLLSAAAYFSPPTFTPIGKYITQLLTLIMLTMGVTLTVDDFKRIIKRPAPVAA 66 + F +W ++ + + P FT I YIT L +IM MG+TL DDFK ++++P V Sbjct: 13 QTFGIWVIVFAVLGFSFPSLFTWISSYITIFLGIIMFGMGLTLQADDFKELVRKPWQVII 72 Query: 67 GIILHYLVMPLAAWIIAKVLHMPPDLTAGMVLVGSVASGTASNVMIYLSRGDVALSVTIS 126 G+I Y +MPL A+ +A LH+P ++ G++LVG GTASNVM +L++G+ ALSV ++ Sbjct: 73 GVIAQYTIMPLVAFGLAFGLHLPAEIAVGVILVGCCPGGTASNVMTFLAKGNTALSVAVT 132 Query: 127 TLSALVSVFATPLLTELYVDASIHFDAHAMLMSIVQIVVLPIAVGLVLNLFAGNLIRRIE 186 T+S L++ TPLL L+ + ++ +SI+Q V+ PI GL++ +F + + Sbjct: 133 TISTLLAPVVTPLLIMLFAKEWLPVSPGSLFISILQAVLFPIIAGLIVKMFFRKQVAKAV 192 Query: 187 PYLSLVSMVAILLIIAAVVAGSQASIASVGLVVLVGVILHNGLGLLGGYWGGRLLGFDEA 246 L LVS++ I+ I++AVV+G++ ++ GL++ VILHNG+G L G+ +LL D Sbjct: 193 HALPLVSVIGIVAIVSAVVSGNRENLLQSGLLIFSVVILHNGIGYLLGFLCAKLLKMDYP 252 Query: 247 VCRTLAIEVGMQNSGLAAALGKLYFTPVAALPGALFSVWHNLSGSLLAGYWRGRPPRD 304 + +AIEVGMQNSGL AAL +F+P++A+P A+FSVWHNLSGS+LA YW + + Sbjct: 253 SQKAIAIEVGMQNSGLGAALATAHFSPLSAVPSAIFSVWHNLSGSMLATYWSKKVKKK 310