BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4550.p (307 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3266 [R] COG0313 Predicted methyltransferases Rso Ralstonia s... 294 1e-79 YPO3547 [R] COG0313 Predicted methyltransferases Ype Yersinia pe... 280 3e-75 VC0582 [R] COG0313 Predicted methyltransferases Vch Vibrio cholerae 266 3e-71 HI1654 [R] COG0313 Predicted methyltransferases Hin Haemophilus ... 262 8e-70 yraL [R] COG0313 Predicted methyltransferases Eco Escherichia co... 261 2e-69 >RSc3266 [R] COG0313 Predicted methyltransferases Rso Ralstonia solanacearum Length = 300 Score = 294 bits (753), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 169/292 (57%), Positives = 207/292 (70%), Gaps = 7/292 (2%) Query: 15 AAQQTYPVSALYVLATPIGNVCDISLRGLHVLALADAVACEDTRNTSQLLQRYGLSKQLL 74 A Q YP ALYV+ATPIGN D+SLR HVL LADAVACEDTRNT QLL R GLS+ LL Sbjct: 10 AHDQHYPAGALYVVATPIGNAADVSLRARHVLGLADAVACEDTRNTGQLLHRLGLSRPLL 69 Query: 75 ATHEHNEREAAAKIIERLQAGQRVALVSDAGTPAVSDPGARVVDAVRAAGFQVIPLPGAS 134 A HEHNEREAAA+I+ERL G+R+A VSDAGTP VSDPGAR+V+AVRAAG +VIPLPGAS Sbjct: 70 AAHEHNEREAAARIVERLARGERIAYVSDAGTPGVSDPGARIVEAVRAAGQRVIPLPGAS 129 Query: 135 AAVTALSASG----LADARFLFVGFLPAKTRQRETALQELVDQQAALVFYEAPHRIVETV 190 A VTALSA+G + +F FVGFLP K QR+TA+++ A V YEAPHRI + Sbjct: 130 AVVTALSAAGALLETSAGQFTFVGFLPPKAGQRDTAIRQWAAHGPAWVLYEAPHRI-DAT 188 Query: 191 QSMLQVFGPTRQVVLARELTKLFEHIHRCPLGEAPAWLEQDANRQRGEFVVLLEGAQPVE 250 + L P R++++ RELTKLFE I P EAPAWL DA+ +GEFV+++EGA E Sbjct: 189 LAALAAHLPARRLLIGRELTKLFEQIVVLPAAEAPAWLAADASHGKGEFVLVVEGAGAQE 248 Query: 251 GEDA--EGERVLRILLEELPVKQAAALAAQITGQKKNALYERALQIRQGAQE 300 ++VLR+LL ELP K+AA LA ITG +ALY+ AL ++ ++ Sbjct: 249 AAPTALAADQVLRLLLAELPAKRAAKLAGAITGAPVDALYQSALALKNDGRD 300 >YPO3547 [R] COG0313 Predicted methyltransferases Ype Yersinia pestis Length = 299 Score = 280 bits (717), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 149/286 (52%), Positives = 209/286 (73%), Gaps = 7/286 (2%) Query: 23 SALYVLATPIGNVCDISLRGLHVLALADAVACEDTRNTSQLLQRYGLSKQLLATHEHNER 82 S LYV+ TPIGN+ DI+ R L VL D +A EDTR+T LLQ + ++ +L A H+HNE+ Sbjct: 12 STLYVVPTPIGNLGDITHRALEVLKGVDLIAAEDTRHTGLLLQHFAINARLFALHDHNEQ 71 Query: 83 EAAAKIIERLQAGQRVALVSDAGTPAVSDPGARVVDAVRAAGFQVIPLPGASAAVTALSA 142 + A +++ +LQ GQ +ALVSDAGTP ++DPG +V R AG +V+PLPGA AA+TALSA Sbjct: 72 QKADQLLAKLQEGQSIALVSDAGTPLINDPGYHLVRRCREAGIRVVPLPGACAAITALSA 131 Query: 143 SGLADARFLFVGFLPAKTRQRETALQELVDQQAALVFYEAPHRIVETVQSMLQVFGPTRQ 202 +GLA RF + GFLPAKT+ R+ LQ L+++ L+FYE+ HR++E++Q M+ V GP R Sbjct: 132 AGLASDRFCYEGFLPAKTKGRKDTLQALIEEPRTLIFYESTHRLLESLQDMVTVLGPQRY 191 Query: 203 VVLARELTKLFEHIHRCPLGEAPAWLEQDANRQRGEFVVLLEGAQPVEGED---AEGERV 259 VVLARELTK +E IH P+GE AW++++ R+RGE V+++EG + V+ +D A+ R Sbjct: 192 VVLARELTKTWESIHGAPVGELLAWVKEEETRRRGEMVLIVEGHK-VQSDDALPADALRT 250 Query: 260 LRILLEELPVKQAAALAAQITGQKKNALYERALQIRQG---AQEDD 302 L +L +ELP+K+AAALAA+I G KKNALY+ AL+ +QG +EDD Sbjct: 251 LALLQKELPLKKAAALAAEIHGVKKNALYKYALEQQQGDVETEEDD 296 >VC0582 [R] COG0313 Predicted methyltransferases Vch Vibrio cholerae Length = 288 Score = 266 bits (681), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 139/282 (49%), Positives = 186/282 (65%), Gaps = 6/282 (2%) Query: 17 QQTYPVSA--LYVLATPIGNVCDISLRGLHVLALADAVACEDTRNTSQLLQRYGLSKQLL 74 +T P A LY++ TPIGN+ DI+ R L VLA D +A EDTR+T +LL + +S + Sbjct: 4 NKTVPNGAPILYIVPTPIGNLGDITQRALDVLASVDMIAVEDTRHTGKLLAHFNISTKTF 63 Query: 75 ATHEHNEREAAAKIIERLQAGQRVALVSDAGTPAVSDPGARVVDAVRAAGFQVIPLPGAS 134 A H+HNE++ A ++++L +G +ALVSDAGTP +SDPG +V R AG +V+PLPG Sbjct: 64 ALHDHNEQQKAQVLVDKLLSGLSIALVSDAGTPLISDPGYHLVTQCRQAGVKVVPLPGPC 123 Query: 135 AAVTALSASGLADARFLFVGFLPAKTRQRETALQELVDQQAALVFYEAPHRIVETVQSML 194 A +TALSASGL F F GFLPAK++ R+ L E+ +FYE+PHRI E++Q ML Sbjct: 124 AVITALSASGLPSDSFSFEGFLPAKSKARKDKLLEIAKVSRTCIFYESPHRICESLQDML 183 Query: 195 QVFGPTRQVVLARELTKLFEHIHRCPLGEAPAWLEQDANRQRGEFVVLLEGAQPVEGED- 253 V G R+VVLARELTK FE I PL E W+ +D NR++GE V+L+ G + GE Sbjct: 184 DVLGGEREVVLARELTKTFETIQGMPLAELITWIAEDDNRKKGEMVLLVHGYRDA-GEQQ 242 Query: 254 --AEGERVLRILLEELPVKQAAALAAQITGQKKNALYERALQ 293 E R L IL +ELP+K+AAAL A+I KKNALY+ L+ Sbjct: 243 LPDEALRTLTILTKELPLKKAAALVAEIHQLKKNALYKWGLE 284 >HI1654 [R] COG0313 Predicted methyltransferases Hin Haemophilus influenzae Length = 283 Score = 262 bits (669), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 126/271 (46%), Positives = 181/271 (66%), Gaps = 3/271 (1%) Query: 25 LYVLATPIGNVCDISLRGLHVLALADAVACEDTRNTSQLLQRYGLSKQLLATHEHNEREA 84 LY++ATPIGN+ DI+ R L A D +A EDTR++ LL YG+ K A H+HNE+E Sbjct: 8 LYIVATPIGNLQDITQRALETFAQVDLIAAEDTRHSGLLLSHYGIKKPFFALHDHNEQEK 67 Query: 85 AAKIIERLQAGQRVALVSDAGTPAVSDPGARVVDAVRAAGFQVIPLPGASAAVTALSASG 144 A ++E+L+ G +AL+SDAGTP +SDPG +V R AG +V+PLPGA AA+TAL ASG Sbjct: 68 AHILVEKLKQGSNIALISDAGTPLISDPGFHLVRQCREAGIRVVPLPGACAAITALCASG 127 Query: 145 LADARFLFVGFLPAKTRQRETALQELVDQQAALVFYEAPHRIVETVQSMLQVFGPTRQVV 204 +A RF F GFLPAK++ R+ L+ + ++ L+FYE+ HRI++T++ M V G R +V Sbjct: 128 IASDRFCFEGFLPAKSKARKDKLENIAEEDRTLIFYESTHRILDTLEDMQAVLGEERYIV 187 Query: 205 LARELTKLFEHIHRCPLGEAPAWLEQDANRQRGEFVVLLEGAQPVEGED---AEGERVLR 261 LARE+TK +E I + WL +D NR +GE V+++EG + D + + L Sbjct: 188 LAREMTKTWETITGNTIKNLREWLLEDPNRTKGEMVLIVEGKPKSDNNDEISPQAVKALE 247 Query: 262 ILLEELPVKQAAALAAQITGQKKNALYERAL 292 ++ EELP+K+AAA+ A++ G KKNALY+ L Sbjct: 248 LIAEELPLKKAAAIVAELYGYKKNALYQFGL 278 >yraL [R] COG0313 Predicted methyltransferases Eco Escherichia coli K12 Length = 286 Score = 261 bits (666), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 137/271 (50%), Positives = 196/271 (72%), Gaps = 3/271 (1%) Query: 25 LYVLATPIGNVCDISLRGLHVLALADAVACEDTRNTSQLLQRYGLSKQLLATHEHNEREA 84 LY++ TPIGN+ DI+ R L VL D +A EDTR+T LLQ +G++ +L A H+HNE++ Sbjct: 14 LYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQK 73 Query: 85 AAKIIERLQAGQRVALVSDAGTPAVSDPGARVVDAVRAAGFQVIPLPGASAAVTALSASG 144 A ++ +LQ GQ +ALVSDAGTP ++DPG +V R AG +V+PLPG AA+TALSA+G Sbjct: 74 AETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAG 133 Query: 145 LADARFLFVGFLPAKTRQRETALQELVDQQAALVFYEAPHRIVETVQSMLQVFGPTRQVV 204 L RF + GFLPAK++ R AL+ + + L+FYE+ HR++++++ ++ V G +R VV Sbjct: 134 LPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVV 193 Query: 205 LARELTKLFEHIHRCPLGEAPAWLEQDANRQRGEFVVLLEGAQPVEGED--AEGERVLRI 262 LARELTK +E IH P+GE AW+++D NR++GE V+++EG + E ED A+ R L + Sbjct: 194 LARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQE-EDLPADALRTLAL 252 Query: 263 LLEELPVKQAAALAAQITGQKKNALYERALQ 293 L ELP+K+AAALAA+I G KKNALY+ AL+ Sbjct: 253 LQAELPLKKAAALAAEIHGVKKNALYKYALE 283