BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4509.p (213 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00081 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme S... 144 1e-34 CC3320 [R] COG1011 Predicted hydrolase (HAD superfamily) Ccr Cau... 136 4e-32 BMEI1443 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme B... 135 9e-32 mll7522 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Me... 133 3e-31 AGc1458 [R] COG1011 Predicted hydrolase (HAD superfamily) Atu Ag... 124 1e-28 >SMc00081 [R] COG1011 Predicted hydrolase (HAD superfamily) Sme Sinorhizobium meliloti Length = 218 Score = 144 bits (364), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 75/203 (36%), Positives = 114/203 (56%), Gaps = 5/203 (2%) Query: 9 IRAVVFDFGGVLLDWNPQHLYRKLIADEQERHHFLTHICSPEWNVQQDGGRTLAEGTAAL 68 IR +VFD G VL+ ++P Y +L+ DE ER F ++C+ +WN++QD GR+ E A L Sbjct: 6 IRHIVFDIGKVLIHYDPNLPYSRLVPDEAERSWFFANVCTSDWNIEQDRGRSWEEAEAIL 65 Query: 69 VQQHPQHETLIRAFYDRWIEMLPGPLPEGVALLRELHAQQVPLFGLTNWSAETYPHARDY 128 ++ HP+ E IRAF W EM+P E VA++ L A + LTN++++T+ A+ Sbjct: 66 IRNHPEREDHIRAFRRHWHEMVPHAYVETVAIMGGLIADGWDVTMLTNFASDTFREAQKL 125 Query: 129 HDFLQLFLDIVVSGHERCIKPEPRIFQIALERYSRHLPNLKPEELVFIDDLQKNIDGCRA 188 + FL L + VSG R IKP+ I++ E + +L P +FIDD N++G RA Sbjct: 126 YPFLTLPRGVTVSGDVRLIKPDLAIYRTHAEAF-----DLDPGATLFIDDSAANVEGARA 180 Query: 189 LGWHGIHHVDVAETRAQLRGLGL 211 GWH + +A L G+ Sbjct: 181 AGWHAVQFTGAERLKADLAAYGI 203 >CC3320 [R] COG1011 Predicted hydrolase (HAD superfamily) Ccr Caulobacter vibrioides Length = 205 Score = 136 bits (342), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 82/213 (38%), Positives = 121/213 (56%), Gaps = 11/213 (5%) Query: 1 MTFSAPSPIRAVVFDFGGVLLDWNPQHLYRKLIADEQERHHFLTHICSPEWNVQQDGGRT 60 MT S P RAV++D G V++ W+P+ LY K+ + + FL+H+C+ +W+V+ D G + Sbjct: 1 MTRSRP---RAVLWDVGNVIVRWDPRALYAKIFKEPADLDRFLSHVCTLDWHVEHDRGVS 57 Query: 61 LAEGTAALVQQHPQHETLIRAFYDRWIEMLPGPLPEGVALLRELHAQQVPLFGLTNWSAE 120 A+ A L+ + P+H IRA+ +R+ EML GP+PE V+++ L A++ P F LTN Sbjct: 58 FADNAAPLIARFPEHAAEIRAWDERFDEMLSGPIPETVSVIEALAARETPQFALTNMPQS 117 Query: 121 TYP--HARDYHDFLQLFLDIVVSGHERCIKPEPRIFQIALERYSRHLPNLKPEELVFIDD 178 +P A+ F F D VVSG E IKP RI++I LER L ++L+FIDD Sbjct: 118 KWPIVQAKSPAHFGH-FRDAVVSGDEGVIKPHRRIYEIVLERT-----GLAADDLLFIDD 171 Query: 179 LQKNIDGCRALGWHGIHHVDVAETRAQLRGLGL 211 NI +G+H H D A R + GL Sbjct: 172 SAANIAAAAEMGFHTHHFTDPAALREAVASHGL 204 >BMEI1443 [R] COG1011 Predicted hydrolase (HAD superfamily) Bme Brucella melitensis Length = 205 Score = 135 bits (339), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 73/205 (35%), Positives = 109/205 (53%), Gaps = 5/205 (2%) Query: 7 SPIRAVVFDFGGVLLDWNPQHLYRKLIADEQERHHFLTHICSPEWNVQQDGGRTLAEGTA 66 SP++ VVFD G VL+ ++P+ + +I D ER FL +IC+ WN++QD GR+ E A Sbjct: 4 SPVKHVVFDIGKVLIHYDPELAFLDIIPDAGERRWFLENICTSAWNIEQDRGRSWQEAEA 63 Query: 67 ALVQQHPQHETLIRAFYDRWIEMLPGPLPEGVALLRELHAQQVPLFGLTNWSAETYPHAR 126 L++ HPQH IRAF W M+P + V +LR L A + LTN++++T+ A+ Sbjct: 64 LLLESHPQHHDHIRAFRRNWSRMVPHAYDDSVEILRGLIAAGHDVTMLTNFASDTFREAQ 123 Query: 127 DYHDFLQLFLDIVVSGHERCIKPEPRIFQIALERYSRHLPNLKPEELVFIDDLQKNIDGC 186 FL + VSG R IKP+ I+ + + L P +FIDD N++G Sbjct: 124 ARFPFLTESRGVTVSGDIRLIKPDRAIYDHHVASF-----GLDPAATLFIDDTMHNVEGA 178 Query: 187 RALGWHGIHHVDVAETRAQLRGLGL 211 + GW +H A+ LR L Sbjct: 179 KQAGWQAVHFTSAAKLADDLRARQL 203 >mll7522 [R] COG1011 Predicted hydrolase (HAD superfamily) Mlo Mesorhizobium loti Length = 212 Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 71/205 (34%), Positives = 110/205 (53%), Gaps = 5/205 (2%) Query: 7 SPIRAVVFDFGGVLLDWNPQHLYRKLIADEQERHHFLTHICSPEWNVQQDGGRTLAEGTA 66 + IR +VFD G VL+ ++P + +LI D +ER F ++C+ +WN++QD GR+ E A Sbjct: 2 TEIRHIVFDIGRVLIHYDPNIPFSRLIPDAEERKWFFDNVCTHDWNIEQDRGRSWEEAEA 61 Query: 67 ALVQQHPQHETLIRAFYDRWIEMLPGPLPEGVALLRELHAQQVPLFGLTNWSAETYPHAR 126 L+ HP H IR F W +M+P + VA++ L + LTN++++T AR Sbjct: 62 LLIADHPDHAENIRNFRRHWHDMVPHAYDDSVAIMLGLIESGHDVTMLTNFASDTLAEAR 121 Query: 127 DYHDFLQLFLDIVVSGHERCIKPEPRIFQIALERYSRHLPNLKPEELVFIDDLQKNIDGC 186 DFL + +SG IKP+ I+ + + L+P +FIDD QKN+DG Sbjct: 122 KRFDFLNRPRGVTISGEIGKIKPDRDIYDHHVAAFG-----LEPSATLFIDDSQKNVDGA 176 Query: 187 RALGWHGIHHVDVAETRAQLRGLGL 211 +A GW + D +A L LG+ Sbjct: 177 KAAGWQAVLFTDARTLQADLERLGI 201 >AGc1458 [R] COG1011 Predicted hydrolase (HAD superfamily) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 203 Score = 124 bits (311), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 66/207 (31%), Positives = 110/207 (53%), Gaps = 5/207 (2%) Query: 7 SPIRAVVFDFGGVLLDWNPQHLYRKLIADEQERHHFLTHICSPEWNVQQDGGRTLAEGTA 66 + I +VFD G VL+ ++P Y +LI D ER F ++C+ +WN++QD GR + A Sbjct: 2 TKIDHIVFDIGKVLIHYDPHIPYSRLIPDADERQWFFENVCTHDWNLEQDRGRRWEDAEA 61 Query: 67 ALVQQHPQHETLIRAFYDRWIEMLPGPLPEGVALLRELHAQQVPLFGLTNWSAETYPHAR 126 L+++ P+ E IRAF W EM+ + VA++ L + LTN++++T+ A+ Sbjct: 62 LLLERFPEREEHIRAFRKFWHEMVSHSYDDSVAIMVALIDSGHDVTMLTNFASDTFREAQ 121 Query: 127 DYHDFLQLFLDIVVSGHERCIKPEPRIFQIALERYSRHLPNLKPEELVFIDDLQKNIDGC 186 FL L + VSG + +KP+ I+ + + + L P +FIDD N++G Sbjct: 122 KMFPFLTLPRGVTVSGDVKLLKPDVAIYHLHAKEF-----GLNPATSLFIDDTLANVEGA 176 Query: 187 RALGWHGIHHVDVAETRAQLRGLGLPV 213 +A GW +H + + LR G+ V Sbjct: 177 KAAGWQAVHFTGAEKLKQDLRAYGVEV 203