BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4501.p (466 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZhydH [T] COG0642 Signal transduction histidine kinase EcZ Esche... 113 8e-25 ECs4926 [T] COG0642 Signal transduction histidine kinase Ecs Esc... 112 1e-24 hydH [T] COG0642 Signal transduction histidine kinase Eco Escher... 112 2e-24 atoS_3 [T] COG0642 Signal transduction histidine kinase Eco Esch... 112 2e-24 PA5484 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 111 3e-24 >ZhydH [T] COG0642 Signal transduction histidine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 458 Score = 113 bits (283), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 84/266 (31%), Positives = 139/266 (52%), Gaps = 18/266 (6%) Query: 200 LLAASALLLAFVIISGVWLGATLTRWRGQSERLAAQLAQSERLATLGRVAAGMAHEIRNP 259 L A + +LLA V+ S W R+ + L ++ + E+L LG +AAG+AHEIRNP Sbjct: 198 LFALATVLLASVL-SFFWY----RRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNP 252 Query: 260 IGAMRMKAENALAAPPQVRQTRVTGALEMVVSQTERLDALVASLLALAQPFQVQRQVLDL 319 + +++ A+ P + +++ + +RL+ +V+ LL L +P + Q +DL Sbjct: 253 LSSIKGLAKYFAERAPAGGEAHQLA--QVMAKEADRLNRVVSELLELVKPTHLALQAVDL 310 Query: 320 AAWIDERRQAHAELAEKHQVQLQ--AAIDLPSFTGGLATSALDPVQMARALDNLLLNALA 377 I+ Q ++ A ++QL+ A LP DP ++ + L NL LNA+ Sbjct: 311 NTLINHSLQLVSQDANCREIQLRFTANDTLPEIQA-------DPDRLTQVLLNLYLNAIQ 363 Query: 378 HCSAGGRIEIGARRQSNGRLLLWVADDGPGVPAELRDSLFDPFVSQRSGGTGLGLVLVRE 437 G I + A ZS + + V D G G+ A+ +++F P+ + ++ GTGLGL +V Sbjct: 364 AIGQHGVISVTAX-ZSGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHN 422 Query: 438 IVHAHGGEITLAS-AARGARFEMELP 462 IV HGG I +AS +GARF + LP Sbjct: 423 IVEQHGGTIQVASLEGKGARFTLWLP 448 >ECs4926 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 458 Score = 112 bits (281), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 18/266 (6%) Query: 200 LLAASALLLAFVIISGVWLGATLTRWRGQSERLAAQLAQSERLATLGRVAAGMAHEIRNP 259 L A + +LLA V+ S W R+ + L ++ + E+L LG +AAG+AHEIRNP Sbjct: 198 LFALATVLLASVL-SFFWY----RRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNP 252 Query: 260 IGAMRMKAENALAAPPQVRQTRVTGALEMVVSQTERLDALVASLLALAQPFQVQRQVLDL 319 + +++ A+ P + +++ + +RL+ +V+ LL L +P + Q +DL Sbjct: 253 LSSIKGLAKYFAERAPAGGEAHQLA--QVMAKEADRLNRVVSELLELVKPTHLALQAVDL 310 Query: 320 AAWIDERRQAHAELAEKHQVQLQ--AAIDLPSFTGGLATSALDPVQMARALDNLLLNALA 377 I+ Q ++ A ++QL+ A LP DP ++ + L NL LNA+ Sbjct: 311 NTLINHSLQLVSQDANCREIQLRFTANDTLPEIQA-------DPDRLTQVLLNLYLNAIQ 363 Query: 378 HCSAGGRIEIGARRQSNGRLLLWVADDGPGVPAELRDSLFDPFVSQRSGGTGLGLVLVRE 437 G I + A G + + V D G G+ A+ +++F P+ + ++ GTGLGL +V Sbjct: 364 AIGQHGVISVTASESGAG-VKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHN 422 Query: 438 IVHAHGGEITLAS-AARGARFEMELP 462 IV HGG I +AS +GARF + LP Sbjct: 423 IVEQHGGTIQVASLEGKGARFTLWLP 448 >hydH [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 465 Score = 112 bits (280), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 83/266 (31%), Positives = 137/266 (51%), Gaps = 18/266 (6%) Query: 200 LLAASALLLAFVIISGVWLGATLTRWRGQSERLAAQLAQSERLATLGRVAAGMAHEIRNP 259 L A + +LLA V+ S W R+ + L ++ + E+L LG +AAG+AHEIRNP Sbjct: 205 LFALATVLLASVL-SFFWY----RRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNP 259 Query: 260 IGAMRMKAENALAAPPQVRQTRVTGALEMVVSQTERLDALVASLLALAQPFQVQRQVLDL 319 + +++ A+ P + +++ + +RL+ +V+ LL L +P + Q +DL Sbjct: 260 LSSIKGLAKYFAERAPAGGEAHQLA--QVMAKEADRLNRVVSELLELVKPTHLALQAVDL 317 Query: 320 AAWIDERRQAHAELAEKHQVQLQ--AAIDLPSFTGGLATSALDPVQMARALDNLLLNALA 377 I+ Q ++ A ++QL+ A LP DP ++ + L NL LNA+ Sbjct: 318 NTLINHSLQLVSQDANSREIQLRFTANDTLPEIQA-------DPDRLTQVLLNLYLNAIQ 370 Query: 378 HCSAGGRIEIGARRQSNGRLLLWVADDGPGVPAELRDSLFDPFVSQRSGGTGLGLVLVRE 437 G I + A G + + V D G G+ A+ D++F P+ + ++ GTGLGL +V Sbjct: 371 AIGQHGVISVTASESGAG-VKISVTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHN 429 Query: 438 IVHAHGGEITLAS-AARGARFEMELP 462 IV HGG I +AS +G+ F + LP Sbjct: 430 IVEQHGGTIQVASQEGKGSTFTLWLP 455 >atoS_3 [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 278 Score = 112 bits (280), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 77/239 (32%), Positives = 129/239 (53%), Gaps = 14/239 (5%) Query: 226 RGQSERLAAQLAQSERLATLGRVAAGMAHEIRNPIGAMRMKAENALAAPPQVRQTRVTGA 285 R +++R ++AQ+ERLATLG + AG+AHE+RNP+ A+R + Q Sbjct: 43 RKETQR---RMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQ---ILRQQTSDPIHQEY 96 Query: 286 LEMVVSQTERLDALVASLLALAQPFQVQRQVLDLAAWIDERRQAHAELAEKHQVQLQAAI 345 L +V+ + + ++ ++ LL ++P Q Q + L A ++E L +QA + Sbjct: 97 LSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEE------TLVLVQTAGVQARV 150 Query: 346 DLPS-FTGGLATSALDPVQMARALDNLLLNALAHCSAGGRIEIGARRQSNGRLLLWVADD 404 D S L+ D + + L N+L+NA+ SA G+I I + S+ + + + D+ Sbjct: 151 DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIQTWQYSDSQQAISIEDN 210 Query: 405 GPGVPAELRDSLFDPFVSQRSGGTGLGLVLVREIVHAHGGEITLAS-AARGARFEMELP 462 G G+ L+ +FDPF + ++ GTGLGL L + I++AH G+I +AS GA F + LP Sbjct: 211 GCGIDLSLQKKIFDPFFTTKASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILP 269 >PA5484 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 595 Score = 111 bits (278), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/223 (35%), Positives = 120/223 (53%), Gaps = 25/223 (11%) Query: 253 AHEIRNPIGAMRMKA---ENALAAPPQVRQTRVTGALEMVVSQTERLDALVASLLALAQP 309 +HE+R P+ M+M L P + R+ + ++ V + RL L+ LL ++ Sbjct: 384 SHELRTPVTGMQMAFSLLRERLDFPAESREADL---IQTVDEEMSRLVLLINDLLNFSR- 439 Query: 310 FQVQRQVLDLAAW--IDERRQAHAELAEKHQ-----VQLQAAIDLPSFTGGLATSALDPV 362 +Q Q L+LA+ +D QA K + +QL+ +LP LD + Sbjct: 440 YQTGMQKLELASCDLVDLLTQAQQRFIPKGEARRVSLQLELGDELPRLQ-------LDRL 492 Query: 363 QMARALDNLLLNALAHCSAGGRIEIGARRQSNGRLLLWVADDGPGVPAELRDSLFDPFVS 422 Q+ R +DNLL NAL H S GG+I + ARRQ + R+L+ V D+G G+P + +F+PFV Sbjct: 493 QIERVIDNLLENALRHSSEGGQIHLQARRQGD-RVLIAVEDNGEGIPFSQQGRIFEPFVQ 551 Query: 423 --QRSGGTGLGLVLVREIVHAHGGEITLASA-ARGARFEMELP 462 ++ GG GLGL L +EI+ HGG I + S +GARF M LP Sbjct: 552 VGRKKGGAGLGLALCKEIIQLHGGRIAVRSQPGQGARFYMLLP 594