BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4474.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0834 [GEPR] COG0477 Permeases of the major facilitator superf... 514 e-145 YPO0577 [GEPR] COG0477 Permeases of the major facilitator superf... 498 e-141 exuT [GEPR] COG0477 Permeases of the major facilitator superfami... 488 e-137 ZexuT [GEPR] COG0477 Permeases of the major facilitator superfam... 488 e-137 ECs3975 [GEPR] COG0477 Permeases of the major facilitator superf... 488 e-137 >RSp0834 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 435 Score = 514 bits (1323), Expect = e-145, Method: Compositional matrix adjust. Identities = 257/416 (61%), Positives = 314/416 (75%), Gaps = 3/416 (0%) Query: 1 MKYVRGIRWYMVTLVTLALIVNYLARNTLSVAAPTMMKELDMNTQQYSYIVVAWQICYAV 60 M ++G+RW+M+ LV LI+NYLARN L+ AAP + K L + TQQY YIV A+Q Y V Sbjct: 1 MNTIKGLRWWMIGLVLTGLIMNYLARNALAAAAPEVNKVLGITTQQYGYIVAAFQAAYMV 60 Query: 61 MQPVAGYVLDAVGTKIGFGIFALAWSLVCAAAAMATGWQSLAFFRALLGMTEAAGIPGGV 120 MQPVAGYVLD +GTK+GF +FA AWS+VC + A W SLA FRA+LG+TEAAG P + Sbjct: 61 MQPVAGYVLDVLGTKLGFALFAGAWSVVCILHSTAGNWVSLAVFRAMLGVTEAAGFPSAL 120 Query: 121 KASTEWFPAKERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFL 180 +A++EWFPAKERS+A GWFNIGSS+GAL APPLVVW ILHG W+ +F V+GVLG++W L Sbjct: 121 RATSEWFPAKERSIATGWFNIGSSVGALVAPPLVVWCILHGNWRFAFAVIGVLGLVWSAL 180 Query: 181 WMLFYKSPRDQKLLSPEERAYILDGQEK-AP-EKVQRESWTKIVRSQNFWSIAIPRFLSE 238 W + Y+ P LS EE AYI GQE AP + SW +I+ + FW IAIPRFL+E Sbjct: 181 WFMLYRVPARHPRLSAEEHAYIRAGQETPAPGADAVKPSWREIMSGRRFWGIAIPRFLTE 240 Query: 239 PAWQTFNAWIPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPLFHKHLKVSLFT 298 PAWQTFN WIPLYMATERHMN+KEIAMFAWLPFLAAD+GCVLGGYL+P + K SL T Sbjct: 241 PAWQTFNFWIPLYMATERHMNLKEIAMFAWLPFLAADVGCVLGGYLAPWYQKRFSTSLIT 300 Query: 299 SRKLVMLVGSLAMIGPACVGFVDSPYVAIGLLSIGGFAHQTLSGALYSITSDVFTRNQVA 358 SRK+VM+ G++ MIGPAC+G SPY AI L +GGFAHQTLSGALY++TSDVF +++V Sbjct: 301 SRKMVMVTGAVCMIGPACIGLATSPYTAIALFCVGGFAHQTLSGALYTLTSDVFGKHEVG 360 Query: 359 TATGLTGMSGYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIAR-PR 413 TA GL GMSG+LG TLF+L G L + IGY PLF LA FD+ A V++ + R PR Sbjct: 361 TAVGLAGMSGFLGGTLFSLAVGTLASTIGYNPLFAALALFDIAAAIVMWNVLREPR 416 >YPO0577 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 434 Score = 498 bits (1283), Expect = e-141, Method: Compositional matrix adjust. Identities = 231/415 (55%), Positives = 309/415 (74%), Gaps = 2/415 (0%) Query: 1 MKYVRGIRWYMVTLVTLALIVNYLARNTLSVAAPTMMKELDMNTQQYSYIVVAWQICYAV 60 M+ ++G+RWYM+ LVT+ I+ YL RN ++VAAPT+ ++L + TQQYSYI+ A+ Y + Sbjct: 2 MRKIKGLRWYMIALVTVGTILGYLTRNAIAVAAPTLQEQLHITTQQYSYIIAAYSAAYTL 61 Query: 61 MQPVAGYVLDAVGTKIGFGIFALAWSLVCAAAAMATGWQSLAFFRALLGMTEAAGIPGGV 120 MQPVAGYVLD +GTK+G+ +FA+ W++ C + A+A+ W LA R +GM EAA IP G+ Sbjct: 62 MQPVAGYVLDVMGTKVGYAMFAVMWAIFCMSTALASSWGGLAIARGAVGMAEAAMIPAGL 121 Query: 121 KASTEWFPAKERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFL 180 KAS+EWFPAKERS+A+G+FN+GSSIG + APPLVVW I+ W+M+F++ GVL ++W Sbjct: 122 KASSEWFPAKERSIAVGYFNVGSSIGGMIAPPLVVWAIVMHSWQMAFIITGVLSLIWAIA 181 Query: 181 WMLFYKSPRDQKLLSPEERAYILDGQE--KAPEKVQRESWTKIVRSQNFWSIAIPRFLSE 238 W++ YK P+DQK LS EER YIL GQE + ++ S +I+R++ FW IAIPRFL+E Sbjct: 182 WLILYKHPKDQKRLSDEEREYILSGQEAQHSTANAKKMSAMQIIRNRQFWGIAIPRFLAE 241 Query: 239 PAWQTFNAWIPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPLFHKHLKVSLFT 298 PAW TFNAWIPL+M N+KEIAMFAW+P L AD+GC+LGGYL PLF K+ KV+L Sbjct: 242 PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADVGCILGGYLPPLFQKYFKVNLIV 301 Query: 299 SRKLVMLVGSLAMIGPACVGFVDSPYVAIGLLSIGGFAHQTLSGALYSITSDVFTRNQVA 358 SRKLV+ +G + MIGP +G SPY AI LL IGGFAHQ LSGAL +++SDVF RN+VA Sbjct: 302 SRKLVVTMGGVLMIGPGTIGLFTSPYAAIALLCIGGFAHQALSGALITLSSDVFGRNEVA 361 Query: 359 TATGLTGMSGYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPR 413 TA GLTGM+ + +TLF L+ G L +G+ PLF LA FDL+AV V++ + + R Sbjct: 362 TANGLTGMAAWTASTLFALVVGALADTMGFSPLFAALAVFDLLAVVVIWTVLQDR 416 >exuT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 472 Score = 488 bits (1255), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/418 (55%), Positives = 313/418 (74%), Gaps = 2/418 (0%) Query: 1 MKYVRGIRWYMVTLVTLALIVNYLARNTLSVAAPTMMKELDMNTQQYSYIVVAWQICYAV 60 M+ ++G+RWYM+ LVTL ++ YL RNT++ AAPT+M+EL+++TQQYSYI+ A+ Y V Sbjct: 41 MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTV 100 Query: 61 MQPVAGYVLDAVGTKIGFGIFALAWSLVCAAAAMATGWQSLAFFRALLGMTEAAGIPGGV 120 MQPVAGYVLD +GTKIG+ +FA+ W++ C A A+A W LA R +G EAA IP G+ Sbjct: 101 MQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGL 160 Query: 121 KASTEWFPAKERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFL 180 KAS+EWFPAKERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W Sbjct: 161 KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMA 220 Query: 181 WMLFYKSPRDQKLLSPEERAYILDGQEKAPE--KVQRESWTKIVRSQNFWSIAIPRFLSE 238 W++FYK PRDQK L+ EER YI++GQE + ++ S +I+R++ FW IA+PRFL+E Sbjct: 221 WLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAE 280 Query: 239 PAWQTFNAWIPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPLFHKHLKVSLFT 298 PAW TFNAWIPL+M N+KEIAMFAW+P L AD+GC+LGGYL PLF + V+L Sbjct: 281 PAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIV 340 Query: 299 SRKLVMLVGSLAMIGPACVGFVDSPYVAIGLLSIGGFAHQTLSGALYSITSDVFTRNQVA 358 SRK+V+ +G++ MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF RN+VA Sbjct: 341 SRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVA 400 Query: 359 TATGLTGMSGYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRPEV 416 TA GLTGMS +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P + Sbjct: 401 TANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAI 458 >ZexuT [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 472 Score = 488 bits (1255), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/418 (55%), Positives = 313/418 (74%), Gaps = 2/418 (0%) Query: 1 MKYVRGIRWYMVTLVTLALIVNYLARNTLSVAAPTMMKELDMNTQQYSYIVVAWQICYAV 60 M+ ++G+RWYM+ LVTL ++ YL RNT++ AAPT+M+EL+++TQQYSYI+ A+ Y V Sbjct: 41 MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTV 100 Query: 61 MQPVAGYVLDAVGTKIGFGIFALAWSLVCAAAAMATGWQSLAFFRALLGMTEAAGIPGGV 120 MQPVAGYVLD +GTKIG+ +FA+ W++ C A A+A W LA R +G EAA IP G+ Sbjct: 101 MQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGL 160 Query: 121 KASTEWFPAKERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFL 180 KAS+EWFPAKERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W Sbjct: 161 KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMA 220 Query: 181 WMLFYKSPRDQKLLSPEERAYILDGQEKAPE--KVQRESWTKIVRSQNFWSIAIPRFLSE 238 W++FYK PRDQK L+ EER YI++GQE + ++ S +I+R++ FW IA+PRFL+E Sbjct: 221 WLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAE 280 Query: 239 PAWQTFNAWIPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPLFHKHLKVSLFT 298 PAW TFNAWIPL+M N+KEIAMFAW+P L AD+GC+LGGYL PLF + V+L Sbjct: 281 PAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIV 340 Query: 299 SRKLVMLVGSLAMIGPACVGFVDSPYVAIGLLSIGGFAHQTLSGALYSITSDVFTRNQVA 358 SRK+V+ +G++ MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF RN+VA Sbjct: 341 SRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVA 400 Query: 359 TATGLTGMSGYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRPEV 416 TA GLTGMS +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P + Sbjct: 401 TANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAI 458 >ECs3975 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 472 Score = 488 bits (1255), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/418 (55%), Positives = 313/418 (74%), Gaps = 2/418 (0%) Query: 1 MKYVRGIRWYMVTLVTLALIVNYLARNTLSVAAPTMMKELDMNTQQYSYIVVAWQICYAV 60 M+ ++G+RWYM+ LVTL ++ YL RNT++ AAPT+M+EL+++TQQYSYI+ A+ Y V Sbjct: 41 MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTV 100 Query: 61 MQPVAGYVLDAVGTKIGFGIFALAWSLVCAAAAMATGWQSLAFFRALLGMTEAAGIPGGV 120 MQPVAGYVLD +GTKIG+ +FA+ W++ C A A+A W LA R +G EAA IP G+ Sbjct: 101 MQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGL 160 Query: 121 KASTEWFPAKERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFL 180 KAS+EWFPAKERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W Sbjct: 161 KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMA 220 Query: 181 WMLFYKSPRDQKLLSPEERAYILDGQEKAPE--KVQRESWTKIVRSQNFWSIAIPRFLSE 238 W++FYK PRDQK L+ EER YI++GQE + ++ S +I+R++ FW IA+PRFL+E Sbjct: 221 WLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAE 280 Query: 239 PAWQTFNAWIPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPLFHKHLKVSLFT 298 PAW TFNAWIPL+M N+KEIAMFAW+P L AD+GC+LGGYL PLF + V+L Sbjct: 281 PAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIV 340 Query: 299 SRKLVMLVGSLAMIGPACVGFVDSPYVAIGLLSIGGFAHQTLSGALYSITSDVFTRNQVA 358 SRK+V+ +G++ MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF RN+VA Sbjct: 341 SRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVA 400 Query: 359 TATGLTGMSGYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRPEV 416 TA GLTGMS +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P + Sbjct: 401 TANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAI 458