BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.4463.p         (176 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

L125244 [Q] COG1335 Amidases related to nicotinamidase Lla Lacto...    99   4e-21
SP1745 [Q] COG1335 Amidases related to nicotinamidase Spn Strept...    95   9e-20
CAC3465 [Q] COG1335 Amidases related to nicotinamidase Cac Clost...    82   5e-16
BS_yddQ [Q] COG1335 Amidases related to nicotinamidase Bsu Bacil...    78   8e-15
PA1677 [Q] COG1335 Amidases related to nicotinamidase Pae Pseudo...    77   1e-14

>L125244 [Q] COG1335 Amidases related to nicotinamidase Lla Lactococcus
           lactis
          Length = 176

 Score = 99.4 bits (246), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 53/157 (33%), Positives = 86/157 (54%), Gaps = 4/157 (2%)

Query: 2   TSALLIIDVQQALCSGADAVANAEQTIASINLLSQQARTAGVPVIFVQHADHGALTHDSP 61
           + AL++ID+Q  +C+G   +   E+ I  IN      R A  P+IF+QH D   L  +S 
Sbjct: 16  SDALIVIDMQNEVCAG---IYRREELIEQINQRILTYRKAKKPIIFIQHND-DELIKESF 71

Query: 62  GWQLAAGLHHQADDLYLGKRGSDAFHQTQLEALLQSRGVRQLVICGMQTEFCVESTVRRA 121
           GWQ+   L   + D Y+ K  ++ F+QT+L+ LL    V+ +  CG QTEFCV +T+  A
Sbjct: 72  GWQMIPELLTASTDKYVEKTHANGFYQTELQKLLTDLSVKLIEFCGAQTEFCVNTTLVFA 131

Query: 122 LALGFPVTLAAGAHTTAPNGVLSVADVIAHHQTTLAN 158
             LG+   +  GA +T  +  LS  +++  ++  L +
Sbjct: 132 HGLGYQNWMQRGASSTFDSKWLSAKEIVDFYEKHLWD 168


>SP1745 [Q] COG1335 Amidases related to nicotinamidase Spn Streptococcus
           pneumoniae TIGR4
          Length = 166

 Score = 94.7 bits (234), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 77/137 (56%), Gaps = 4/137 (2%)

Query: 1   MTSALLIIDVQQALCSGADAVANAEQTIASINLLSQQARTAGVPVIFVQHADHGALTHDS 60
           M +A +IIDVQ  L          +  +  I+ L  QAR+  + +I+VQH ++      S
Sbjct: 1   MKTAFIIIDVQNVLVETG---FQTKSLLEKISYLQNQARSKNIEIIYVQHIENSE-AQTS 56

Query: 61  PGWQLAAGLHHQADDLYLGKRGSDAFHQTQLEALLQSRGVRQLVICGMQTEFCVESTVRR 120
             WQL+A L+ +  +    K+ +  F +T L+  L  +G+ +LV+CGMQTE+CV+++V+ 
Sbjct: 57  EDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLCGMQTEYCVDTSVKV 116

Query: 121 ALALGFPVTLAAGAHTT 137
           A   G+ + +  GA TT
Sbjct: 117 AFEYGYQLIVPEGAVTT 133


>CAC3465 [Q] COG1335 Amidases related to nicotinamidase Cac Clostridium
           acetobutylicum
          Length = 178

 Score = 82.4 bits (202), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 79/157 (50%), Gaps = 4/157 (2%)

Query: 4   ALLIIDVQQALCSGADAVANAEQTIASINLLSQQARTAGVPVIFVQHAD-HG-ALTHDSP 61
            L+++D Q  L        N +  I +I  L   AR     V++V+H D  G  L   + 
Sbjct: 5   VLMVVDAQNGLIKKKPY--NHKNVIENIKKLIIMARANNKEVVYVRHDDGEGTELEKGTE 62

Query: 62  GWQLAAGLHHQADDLYLGKRGSDAFHQTQLEALLQSRGVRQLVICGMQTEFCVESTVRRA 121
           GWQ+ + L  ++ +  + K+ + AFH+T L+  L+S+    +++ G+QTE+C+++T++ A
Sbjct: 63  GWQIYSELEPKSGEFIIEKKYNSAFHRTDLKEYLESKNTDTIILVGLQTEYCIDATLKSA 122

Query: 122 LALGFPVTLAAGAHTTAPNGVLSVADVIAHHQTTLAN 158
               + V +    +TT  N  LS   +   +   + N
Sbjct: 123 FDNEYKVIIPKDTNTTFDNEYLSGEKLYKFYNYKIWN 159


>BS_yddQ [Q] COG1335 Amidases related to nicotinamidase Bsu Bacillus
           subtilis
          Length = 180

 Score = 78.2 bits (191), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 5/131 (3%)

Query: 1   MTSALLIIDVQQ-ALCSGADAVANAEQTIASINLLSQQARTAGVPVIFVQHADHGALTH- 58
           MT+ALL+ID+Q     +G  A+ N E+   +   L    R  G PV  VQH   G + H 
Sbjct: 1   MTTALLVIDIQNDYFPNGKMALTNPEKAAQNAAKLLSHFRNTGAPVFHVQHITEGNIAHF 60

Query: 59  ---DSPGWQLAAGLHHQADDLYLGKRGSDAFHQTQLEALLQSRGVRQLVICGMQTEFCVE 115
              ++ G ++   +     +  + K   ++F  T L   LQ  GV++LV+CGM +  C++
Sbjct: 61  FHPNTEGVEIHESVRPLEKETVIVKHMPNSFFNTDLNGKLQEEGVKELVVCGMMSHMCID 120

Query: 116 STVRRALALGF 126
           +TVR A+  G+
Sbjct: 121 ATVRSAVEHGY 131


>PA1677 [Q] COG1335 Amidases related to nicotinamidase Pae Pseudomonas
           aeruginosa
          Length = 198

 Score = 77.4 bits (189), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 56/153 (36%), Positives = 75/153 (49%), Gaps = 7/153 (4%)

Query: 3   SALLIIDVQQALCSGADAVANAEQTIASINLLSQQARTAGVPVIFVQH--ADHGALTHDS 60
           S LLIID Q+   SGA  +   +   A I +L Q AR +G P++ V+H     G      
Sbjct: 23  STLLIIDAQEEYRSGALRLPGLDAAAAEIGVLVQAARASGTPIVHVRHLGIQGGLFDPQG 82

Query: 61  PGWQLAAGLHHQADDLYLGKRGSDAFHQTQLEALLQSRGVRQLVICGMQTEFCVESTVRR 120
           P  Q    L  +A +  + KR  +AF  T+L  LLQ+ G   L++CG  T   V +TVR 
Sbjct: 83  PRGQFLPELQPEAGEKVVEKRLPNAFSGTELHDLLQNHGRLDLIVCGFMTHSSVSTTVRA 142

Query: 121 ALALGFPVTLAAGAHTTAP-----NGVLSVADV 148
           A   G+  TLA  A  T        GVLS AD+
Sbjct: 143 AKDYGYRCTLADSACATRDIPTLNGGVLSAADL 175