BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4460.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1080 [GEPR] COG0477 Permeases of the major facilitator superf... 703 0.0 RSp0834 [GEPR] COG0477 Permeases of the major facilitator superf... 467 e-131 YPO0577 [GEPR] COG0477 Permeases of the major facilitator superf... 431 e-120 STM3134 [GEPR] COG0477 Permeases of the major facilitator superf... 430 e-120 exuT [GEPR] COG0477 Permeases of the major facilitator superfami... 426 e-119 >RSc1080 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 432 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/422 (84%), Positives = 382/422 (90%) Query: 1 LKTIKGLRWWIIVLVCLGTITNYLARNSLGVLAPTLKDELGMSTQQYSYVVAAFQVGYTI 60 +KTIKGLRWWII LVCLGTITNYLARNSLGVLAP LK ELGMSTQQYSYVV AFQ+GYTI Sbjct: 1 MKTIKGLRWWIIALVCLGTITNYLARNSLGVLAPQLKTELGMSTQQYSYVVGAFQIGYTI 60 Query: 61 MQPVCGFVVDLIGLRIGFALFGVLWSLAGVLHAGATGWLSLAGFRALMGLTEAAAIPSGM 120 MQPVCGF+VDLIGLRIGFALF VLWS+AG LHAGA+GWLSLA FR LMGLTEAAAIPSGM Sbjct: 61 MQPVCGFIVDLIGLRIGFALFAVLWSIAGCLHAGASGWLSLASFRGLMGLTEAAAIPSGM 120 Query: 121 KAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRYGWQSAFVVTGVLGFAWAAL 180 KAVAEWFPDKEKSVAVG+FN+GTSLGA+LAPPLV+FL LRYGWQSAFVVTG LGF WAAL Sbjct: 121 KAVAEWFPDKEKSVAVGYFNAGTSLGALLAPPLVVFLSLRYGWQSAFVVTGALGFVWAAL 180 Query: 181 WFAFYRSPHDHAALSEQERTTIVSGQQRPVSAERGKRPVKDVVSSRRFWAIALARFFAEP 240 W+ FYRSP +HA LS E I+ GQ R A RGKRPV++VV+SRRFWAIAL RFFAEP Sbjct: 181 WYGFYRSPREHAKLSATEHDRIIGGQIRSAGAARGKRPVREVVTSRRFWAIALPRFFAEP 240 Query: 241 AWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLVGGYLSPWLINRFRVPLIWS 300 AWQTFSFWIPLY + RH+DLK IA+FAWLPFLAADLGGL+GGYLSP+ + FRVPLIWS Sbjct: 241 AWQTFSFWIPLYLSSARHMDLKEIALFAWLPFLAADLGGLLGGYLSPFFMKFFRVPLIWS 300 Query: 301 RVYGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLSADVFDPEEVGT 360 RV GVVLGA +MIGPAC+GLVASPY AIALFCVGGFAHQMIS LVNTLSADVFDPEEVGT Sbjct: 301 RVCGVVLGAFLMIGPACIGLVASPYQAIALFCVGGFAHQMISTLVNTLSADVFDPEEVGT 360 Query: 361 ASGFAGMSAWIGGLGFSLLVGALADKVGYGPLFGMLGAFDLIGAVLLILLIRGQSNEERA 420 ASGFAGM+AWIGGLGFSL+VGALAD VGYGPLFG+LGAFDLIGA LLILLIRGQS EERA Sbjct: 361 ASGFAGMAAWIGGLGFSLMVGALADTVGYGPLFGLLGAFDLIGATLLILLIRGQSQEERA 420 Query: 421 AR 422 AR Sbjct: 421 AR 422 >RSp0834 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 435 Score = 467 bits (1201), Expect = e-131, Method: Compositional matrix adjust. Identities = 233/413 (56%), Positives = 298/413 (72%), Gaps = 1/413 (0%) Query: 1 LKTIKGLRWWIIVLVCLGTITNYLARNSLGVLAPTLKDELGMSTQQYSYVVAAFQVGYTI 60 + TIKGLRWW+I LV G I NYLARN+L AP + LG++TQQY Y+VAAFQ Y + Sbjct: 1 MNTIKGLRWWMIGLVLTGLIMNYLARNALAAAAPEVNKVLGITTQQYGYIVAAFQAAYMV 60 Query: 61 MQPVCGFVVDLIGLRIGFALFGVLWSLAGVLHAGATGWLSLAGFRALMGLTEAAAIPSGM 120 MQPV G+V+D++G ++GFALF WS+ +LH+ A W+SLA FRA++G+TEAA PS + Sbjct: 61 MQPVAGYVLDVLGTKLGFALFAGAWSVVCILHSTAGNWVSLAVFRAMLGVTEAAGFPSAL 120 Query: 121 KAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRYGWQSAFVVTGVLGFAWAAL 180 +A +EWFP KE+S+A GWFN G+S+GA++APPLV++ L W+ AF V GVLG W+AL Sbjct: 121 RATSEWFPAKERSIATGWFNIGSSVGALVAPPLVVWCILHGNWRFAFAVIGVLGLVWSAL 180 Query: 181 WFAFYRSPHDHAALSEQERTTIVSGQQRPVSAERGKRPV-KDVVSSRRFWAIALARFFAE 239 WF YR P H LS +E I +GQ+ P +P ++++S RRFW IA+ RF E Sbjct: 181 WFMLYRVPARHPRLSAEEHAYIRAGQETPAPGADAVKPSWREIMSGRRFWGIAIPRFLTE 240 Query: 240 PAWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLVGGYLSPWLINRFRVPLIW 299 PAWQTF+FWIPLY ERH++LK IAMFAWLPFLAAD+G ++GGYL+PW RF LI Sbjct: 241 PAWQTFNFWIPLYMATERHMNLKEIAMFAWLPFLAADVGCVLGGYLAPWYQKRFSTSLIT 300 Query: 300 SRVYGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLSADVFDPEEVG 359 SR +V GAV MIGPAC+GL SPYTAIALFCVGGFAHQ +SG + TL++DVF EVG Sbjct: 301 SRKMVMVTGAVCMIGPACIGLATSPYTAIALFCVGGFAHQTLSGALYTLTSDVFGKHEVG 360 Query: 360 TASGFAGMSAWIGGLGFSLLVGALADKVGYGPLFGMLGAFDLIGAVLLILLIR 412 TA G AGMS ++GG FSL VG LA +GY PLF L FD+ A+++ ++R Sbjct: 361 TAVGLAGMSGFLGGTLFSLAVGTLASTIGYNPLFAALALFDIAAAIVMWNVLR 413 >YPO0577 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 434 Score = 431 bits (1107), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/419 (48%), Positives = 292/419 (69%), Gaps = 1/419 (0%) Query: 1 LKTIKGLRWWIIVLVCLGTITNYLARNSLGVLAPTLKDELGMSTQQYSYVVAAFQVGYTI 60 ++ IKGLRW++I LV +GTI YL RN++ V APTL+++L ++TQQYSY++AA+ YT+ Sbjct: 2 MRKIKGLRWYMIALVTVGTILGYLTRNAIAVAAPTLQEQLHITTQQYSYIIAAYSAAYTL 61 Query: 61 MQPVCGFVVDLIGLRIGFALFGVLWSLAGVLHAGATGWLSLAGFRALMGLTEAAAIPSGM 120 MQPV G+V+D++G ++G+A+F V+W++ + A A+ W LA R +G+ EAA IP+G+ Sbjct: 62 MQPVAGYVLDVMGTKVGYAMFAVMWAIFCMSTALASSWGGLAIARGAVGMAEAAMIPAGL 121 Query: 121 KAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRYGWQSAFVVTGVLGFAWAAL 180 KA +EWFP KE+S+AVG+FN G+S+G M+APPLV++ + + WQ AF++TGVL WA Sbjct: 122 KASSEWFPAKERSIAVGYFNVGSSIGGMIAPPLVVWAIVMHSWQMAFIITGVLSLIWAIA 181 Query: 181 WFAFYRSPHDHAALSEQERTTIVSGQQRPVSAERGKR-PVKDVVSSRRFWAIALARFFAE 239 W Y+ P D LS++ER I+SGQ+ S K+ ++ +R+FW IA+ RF AE Sbjct: 182 WLILYKHPKDQKRLSDEEREYILSGQEAQHSTANAKKMSAMQIIRNRQFWGIAIPRFLAE 241 Query: 240 PAWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLVGGYLSPWLINRFRVPLIW 299 PAW TF+ WIPL+ +LK IAMFAW+P L AD+G ++GGYL P F+V LI Sbjct: 242 PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADVGCILGGYLPPLFQKYFKVNLIV 301 Query: 300 SRVYGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLSADVFDPEEVG 359 SR V +G V+MIGP +GL SPY AIAL C+GGFAHQ +SG + TLS+DVF EV Sbjct: 302 SRKLVVTMGGVLMIGPGTIGLFTSPYAAIALLCIGGFAHQALSGALITLSSDVFGRNEVA 361 Query: 360 TASGFAGMSAWIGGLGFSLLVGALADKVGYGPLFGMLGAFDLIGAVLLILLIRGQSNEE 418 TA+G GM+AW F+L+VGALAD +G+ PLF L FDL+ V++ +++ ++ +E Sbjct: 362 TANGLTGMAAWTASTLFALVVGALADTMGFSPLFAALAVFDLLAVVVIWTVLQDRTADE 420 >STM3134 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 430 bits (1105), Expect = e-120, Method: Compositional matrix adjust. Identities = 217/426 (50%), Positives = 289/426 (67%), Gaps = 10/426 (2%) Query: 7 LRWWIIVLVCLGTITNYLARNSLGVLAPTLKDELGMSTQQYSYVVAAFQVGYTIMQPVCG 66 LRWWII LVC+GTI NYL+R+SL V AP + EL QQYS+VV+AFQ+ YTI QP+ G Sbjct: 6 LRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQQYSWVVSAFQLCYTIAQPITG 65 Query: 67 FVVDLIGLRIGFALFGVLWSLAGVLHAGATGWLSLAGFRALMGLTEAAAIPSGMKAVAEW 126 +++D+IGL+IGF +F +LWSL + HA A GW+SLA R LMGLTEA+AIP+G+KA AEW Sbjct: 66 YLMDVIGLKIGFFIFALLWSLINMAHALAGGWISLAFLRGLMGLTEASAIPAGIKASAEW 125 Query: 127 FPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRY-----GWQSAFVVTGVLGFAWAALW 181 FP KE+ +A G FN GTS+GAMLAPPLV++ L + G + AFV+TG +G +A W Sbjct: 126 FPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTFADSGIGTEMAFVITGGIGVLFAITW 185 Query: 182 FAFYRSPHDHAALSEQERTTIVSGQQRPVSAERGKRPVKDVVSSRRFWAIALARFFAEPA 241 F Y SP+ H ++ +E I GQ+ + + K VK++V R FWA+A+ RF A+PA Sbjct: 186 FLIYNSPNKHPWITHKELRYIEDGQESYLQDDNKKPAVKEIVKKRNFWALAITRFLADPA 245 Query: 242 WQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLVGGYLSPWLINRFRVPLIWSR 301 W T SFW+PLY +N HL LK IAMFAWLPFLAAD G + GG+L+ + + + + I +R Sbjct: 246 WGTLSFWMPLYLINVMHLPLKEIAMFAWLPFLAADFGCVAGGFLAKFFMEKMHMTTINAR 305 Query: 302 VYGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLSADVFDPEEVGTA 361 +GAV+MI V + +PY AIAL +GGFAHQ +S +V T+SAD+F EV T Sbjct: 306 RCSFTIGAVLMISIGFVSITTNPYVAIALMSIGGFAHQTLSTVVITMSADLFKKNEVATV 365 Query: 362 SGFAGMSAWIGGLGFSLLVGALADKVGYGPLFGMLGAFDLIGAVLLILLIRGQSNEERAA 421 +G AG +AW+G L F+L +GAL +GYGP F L FD+IGA++L +LI+ Sbjct: 366 AGLAGSAAWMGQLSFNLFMGALVAIIGYGPFFIALSLFDIIGAIILWVLIKDPEKHH--- 422 Query: 422 RTPPRT 427 PP T Sbjct: 423 --PPMT 426 >exuT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 472 Score = 426 bits (1095), Expect = e-119, Method: Compositional matrix adjust. Identities = 216/425 (50%), Positives = 294/425 (69%), Gaps = 3/425 (0%) Query: 1 LKTIKGLRWWIIVLVCLGTITNYLARNSLGVLAPTLKDELGMSTQQYSYVVAAFQVGYTI 60 ++ IKGLRW++I LV LGT+ YL RN++ APTL +EL +STQQYSY++AA+ YT+ Sbjct: 41 MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTV 100 Query: 61 MQPVCGFVVDLIGLRIGFALFGVLWSLAGVLHAGATGWLSLAGFRALMGLTEAAAIPSGM 120 MQPV G+V+D++G +IG+A+F VLW++ A A W LA R +G EAA IP+G+ Sbjct: 101 MQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGL 160 Query: 121 KAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRYGWQSAFVVTGVLGFAWAAL 180 KA +EWFP KE+S+AVG+FN G+S+GAM+APPLV++ + + WQ AF+++G L F WA Sbjct: 161 KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMA 220 Query: 181 WFAFYRSPHDHAALSEQERTTIVSGQ--QRPVSAERGKRPVKDVVSSRRFWAIALARFFA 238 W FY+ P D L+++ER I++GQ Q VS + K V ++ +R+FW IAL RF A Sbjct: 221 WLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAK-KMSVGQILRNRQFWGIALPRFLA 279 Query: 239 EPAWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLVGGYLSPWLINRFRVPLI 298 EPAW TF+ WIPL+ +LK IAMFAW+P L ADLG ++GGYL P F V LI Sbjct: 280 EPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLI 339 Query: 299 WSRVYGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLSADVFDPEEV 358 SR V LGAV+MIGP +GL +PY AI L C+GGFAHQ +SG + TLS+DVF EV Sbjct: 340 VSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEV 399 Query: 359 GTASGFAGMSAWIGGLGFSLLVGALADKVGYGPLFGMLGAFDLIGAVLLILLIRGQSNEE 418 TA+G GMSAW+ F+L+VGALAD +G+ PLF +L FDL+GA+++ +++ + E Sbjct: 400 ATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIE 459 Query: 419 RAART 423 A T Sbjct: 460 VAQET 464