BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4438.p (768 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1927 [E] COG0620 Methionine synthase II (cobalamin-independent... 899 0.0 XF2272 [E] COG0620 Methionine synthase II (cobalamin-independent... 891 0.0 HI1702 [E] COG0620 Methionine synthase II (cobalamin-independent... 862 0.0 NMB0944 [E] COG0620 Methionine synthase II (cobalamin-independen... 861 0.0 NMA1140 [E] COG0620 Methionine synthase II (cobalamin-independen... 859 0.0 >PA1927 [E] COG0620 Methionine synthase II (cobalamin-independent) Pae Pseudomonas aeruginosa Length = 766 Score = 899 bits (2323), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/766 (60%), Positives = 563/766 (73%), Gaps = 12/766 (1%) Query: 1 MTTIHNLGFPRIGARRELKFALESYWKGESSLAALEETGAQLRRRHWQDQ--AALDLVPV 58 M H LGFPRIG RELK A E++WKGE A L G QLR HWQ Q A + L+PV Sbjct: 1 MALAHTLGFPRIGRDRELKKAQEAFWKGELDEAGLRAVGRQLRAAHWQVQKDAGIQLLPV 60 Query: 59 GDFSFYDQVLDMSVTLGNLPARVQDFHGHA---LDNYFRVARGRSAPHAHDSCCAGVAAG 115 GDF++YDQVL S+T G +P R + HG A L F +ARG S DSCC G A Sbjct: 61 GDFAWYDQVLTHSLTFGVIPERFRA-HGEAGPTLHTLFGMARGVS----DDSCCGGAHAQ 115 Query: 116 EMTKWFDTNYHYIVPEFHATTRFTLDASRLLAQVRQAQEQGVQAKPVIIGPVTYLALGKA 175 EMTKWFDTNYHY+VPEF A +F L +L +V +A+ G Q KPV+IGP+TYL LGKA Sbjct: 116 EMTKWFDTNYHYLVPEFSADQQFQLSWEQLFEEVDEARALGHQVKPVLIGPLTYLWLGKA 175 Query: 176 KDGS-DKLALLERLLPVYSQLLDTLAAAGVQWVQIDEPILVTELDADWQHALNHAYHHLK 234 K D+L LL+RLLP+Y Q+ LA GV+WVQIDEPILV +L W++A AY+ L+ Sbjct: 176 KGAEFDRLDLLDRLLPLYGQIFRRLAGQGVEWVQIDEPILVLDLPQAWKNAFERAYNLLQ 235 Query: 235 VCKVKLLLATYFGQLQENGYLAANLPVAGLHVDAIQGREEVTGLLNILPPHKVLSLGVIN 294 +K L+ATYFG L++N LAANLPV GLH+D ++ E+ +L+ LP +KV+SLG++N Sbjct: 236 SEPLKKLVATYFGGLEDNLGLAANLPVDGLHIDLVRAPEQYPSILDRLPAYKVVSLGLVN 295 Query: 295 GRNIWKTDLSALLDWLEPLAQRLGERLWIAPSCSLLHVPVDLAQEEKLDQDIQSWLAFAV 354 GRN+W+ DL L+ + +RLGERLW+APSCSLLH PVDL +E+ LD +++SWLAFAV Sbjct: 296 GRNVWRCDLEKALEVVRHARERLGERLWVAPSCSLLHSPVDLEREDGLDAELKSWLAFAV 355 Query: 355 QKLDELQLIGRALREGRAA-VQDALHANAAALAARRTSPRVHNPAVRAALAQLTPQHGQR 413 QK E+ ++ RA E AA V AL + A A+R +SPR+H PAV+A LA + QR Sbjct: 356 QKCREVAVLARAATEPEAAEVLAALEESRAVQASRASSPRIHKPAVQARLAAIKASDAQR 415 Query: 414 NSHYPERASKQAALLQLPLYPTTTIGSFPQTAEIRQARSHYKAGQLDEAAYRTVMRAEIE 473 S + ER ++Q A L LP +PTTTIGSFPQT+ IR AR +K G+L EA Y M +EI Sbjct: 416 RSPFAERIARQRAGLDLPAFPTTTIGSFPQTSSIRLARQSFKQGKLSEAEYIEAMHSEIR 475 Query: 474 RSVREQEALGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGDI 533 +V+ QE LGLDVLVHGEAERNDMVEYF EQL GY F++FGWVQSYGSRCVKP +++GD+ Sbjct: 476 HAVQIQEQLGLDVLVHGEAERNDMVEYFAEQLDGYVFTRFGWVQSYGSRCVKPAVIYGDL 535 Query: 534 SRPQAMTVEWITHAQSLTSKPMKGMLTGPVTLLNWSFVRDDQPRADSCRQLALAIRQEVL 593 SRP+AMTVEWI +AQSLT K MKGMLTGPVT+L WSF R+D R RQLALAIR EV+ Sbjct: 536 SRPRAMTVEWIRYAQSLTDKVMKGMLTGPVTMLMWSFPREDVSREVQARQLALAIRDEVV 595 Query: 594 DLEAAGVRVIQIDEAALREGLPLRRAQWQHYLNWAVQAFRITANGVADTTQIHTHMCYSE 653 DLEAAG+R++QIDEAA REGLPLRR W HYL WA +AFR+ A+GV D TQIHTHMCYSE Sbjct: 596 DLEAAGIRIVQIDEAAFREGLPLRRNAWPHYLEWATEAFRLCASGVRDETQIHTHMCYSE 655 Query: 654 FNDIIASIADMDADVITIETSRSDMELLDAFDHFNYPNEIGPGVYDIHSPNIPTQEHMVQ 713 FND+I SIA MDADVITIETSRSDMELL+AF+ F+YPNEIGPGVYDIHSP +P++E +V Sbjct: 656 FNDVIESIAAMDADVITIETSRSDMELLEAFEQFDYPNEIGPGVYDIHSPRVPSREEIVA 715 Query: 714 LMQKATERIDARRLWVNPDCGLKTRQWAEVIPALRNMVAAAQTLRA 759 L++KA RI A RLWVNPDCGLKTR W E AL NMVAAA+ LR Sbjct: 716 LLRKAARRIPAERLWVNPDCGLKTRAWPETEAALVNMVAAARELRG 761 >XF2272 [E] COG0620 Methionine synthase II (cobalamin-independent) Xfa Xylella fastidiosa 9a5c Length = 758 Score = 891 bits (2303), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/764 (57%), Positives = 544/764 (71%), Gaps = 12/764 (1%) Query: 1 MTTIHNLGFPRIGARRELKFALESYWKGESSLAALEETGAQLRRRHWQDQ--AALDLVPV 58 MT + NL FPRIGARRELK ALES+W+GE+ L+ T +LR RHWQ Q +DL P Sbjct: 1 MTIVTNLSFPRIGARRELKRALESHWRGETDATQLQHTARELRARHWQLQRDTGVDLPPS 60 Query: 59 GDFSFYDQVLDMSVTLGNLPARVQDF-HGHALDNYFRVARGRSAPHAHDSCCAGVAAGEM 117 DFS YD VLD + +P R + L YF +ARGR A + A EM Sbjct: 61 NDFSLYDHVLDTAFLFDAIPQRYRALADADPLAGYFAMARGRQAD------GIDLHALEM 114 Query: 118 TKWFDTNYHYIVPEFHATTRFTLDASRLLAQVRQAQEQGVQAKPVIIGPVTYLALGKAKD 177 TKWFDTNYHY+VPE H F L ++ +A+ +A G+ +PV++GPV++L L K D Sbjct: 115 TKWFDTNYHYLVPELHRDQHFALRGNKPIAEFEEALALGITTRPVLLGPVSFLLLSKTVD 174 Query: 178 GSDKLALLERLLPVYSQLLDTLAAAGVQWVQIDEPILVTELDADWQHALNHAYHHLKVC- 236 GS++L LLERLLPVY+QLL L A+G +WVQIDEP LV +LDA Q A AY L Sbjct: 175 GSNRLDLLERLLPVYTQLLRQLQASGAEWVQIDEPTLVLDLDAQTQQAFRKAYAALNQGP 234 Query: 237 KVKLLLATYFGQLQENGYLAANLPVAGLHVDAIQGREEVTGLLNILPPHKVLSLGVINGR 296 + KLLL +YFG L +N LA LP GLH+D ++G E++ +LN LP +VLS G++NGR Sbjct: 235 RPKLLLTSYFGPLGDNLELALQLPADGLHIDLVRGTEQLDAVLNTLPAGRVLSAGLVNGR 294 Query: 297 NIWKTDLSALLDWLEPLAQRLG-ERLWIAPSCSLLHVPVDLAQEEKLDQDIQSWLAFAVQ 355 NIW+T L L R+G + +W+APSCSLLHVPVDL QE+ LD D+++WLAFA Q Sbjct: 295 NIWRTALDNALTLARYAQGRIGKDHVWLAPSCSLLHVPVDLEQEKNLDADVRNWLAFAKQ 354 Query: 356 KLDELQLIGRALREGRAAVQDALHANAAALAARRTSPRVHNPAVRAALAQLTPQHGQRNS 415 KL EL+++ AL + + + AL AL ARR SP+VH P V LA LTP QRN+ Sbjct: 355 KLSELRVLADAL-DNKPEAETALTQTRQALEARRQSPKVHRPEVAQRLAALTPDTTQRNT 413 Query: 416 HYPERASKQAALLQLPLYPTTTIGSFPQTAEIRQARSHYKAGQLDEAAYRTVMRAEIERS 475 YP+R+ Q L LP YPTTTIGSFPQT E+R+AR+ +K+G+L E+ Y T ++AE ER Sbjct: 414 AYPQRSQAQQQTLNLPAYPTTTIGSFPQTLEVREARAQFKSGKLSESDYETFLKAETERC 473 Query: 476 VREQEALGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGDISR 535 +R QE +GLDVLVHGE ERNDMVEYFGEQL G+ F++ GWVQSYGSRCVKPPI++GD+ R Sbjct: 474 IRTQEEIGLDVLVHGEFERNDMVEYFGEQLDGFIFTKLGWVQSYGSRCVKPPIIYGDVVR 533 Query: 536 PQAMTVEWITHAQSLTSKPMKGMLTGPVTLLNWSFVRDDQPRADSCRQLALAIRQEVLDL 595 P MTV W +AQSLT KPMKGMLTGPVT+L WSFVRDDQ RA +CRQ+ALA+R EV DL Sbjct: 534 PAPMTVTWSAYAQSLTDKPMKGMLTGPVTMLQWSFVRDDQERAQTCRQIALALRDEVQDL 593 Query: 596 EAAGVRVIQIDEAALREGLPLRRAQWQHYLNWAVQAFRITANGVADTTQIHTHMCYSEFN 655 E AG++VIQIDE A+REGLPLRR +W YLNWAV++FRI ++ V DTTQIHTHMCYSEFN Sbjct: 594 EKAGIKVIQIDEPAIREGLPLRRGEWADYLNWAVESFRIASSNVRDTTQIHTHMCYSEFN 653 Query: 656 DIIASIADMDADVITIETSRSDMELLDAFDHFNYPNEIGPGVYDIHSPNIPTQEHMVQLM 715 DII ++A +DADVI+IETSRS MELLDAF F YPN IGPGVYDIHSP +P +E MV L+ Sbjct: 654 DIIEAVAALDADVISIETSRSRMELLDAFVKFRYPNAIGPGVYDIHSPRVPQEEEMVLLL 713 Query: 716 QKATERIDARRLWVNPDCGLKTRQWAEVIPALRNMVAAAQTLRA 759 +KA + +LWVNPDCGLKTR W E AL+ MV AAQ LRA Sbjct: 714 KKARAVLPPEQLWVNPDCGLKTRGWKETRAALQTMVHAAQRLRA 757 >HI1702 [E] COG0620 Methionine synthase II (cobalamin-independent) Hin Haemophilus influenzae Length = 756 Score = 862 bits (2226), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/766 (55%), Positives = 533/766 (69%), Gaps = 20/766 (2%) Query: 1 MTTIHNLGFPRIGARRELKFALESYWKGESSLAALEETGAQLRRRHWQDQAAL--DLVPV 58 MTT H LGFPR+GA+RELKFA E YW+ E + L + LR ++W+ QAA D V V Sbjct: 1 MTTSHILGFPRVGAKRELKFAQERYWRKELAEQDLLDLAKALREKNWKHQAAANADFVAV 60 Query: 59 GDFSFYDQVLDMSVTLGNLPARVQ-DFHGHALDNYFRVARGRSAPHAHDSCCAGVAAGEM 117 GDF+FYD +LD+ V G +PAR D LD YF++ARG A EM Sbjct: 61 GDFTFYDHILDLQVATGAIPARFGFDSQNLTLDQYFQLARGNKDQFAI----------EM 110 Query: 118 TKWFDTNYHYIVPEFHATTRFTLDASRLLAQVRQAQEQGVQAKPVIIGPVTYLALGKAK- 176 TKWFDTNYHY+VPEF +T F + + + Q+R+A+ G+ KPVI+GP+T+L LGK K Sbjct: 111 TKWFDTNYHYLVPEFQKSTAFKANPAHYVNQIREAKALGLNFKPVIVGPLTFLWLGKEKG 170 Query: 177 DGSDKLALLERLLPVYSQLLDTLAAAGVQWVQIDEPILVTELDADWQHALNHAYHHLKVC 236 + ++ LL +L+PVY ++L+ L A G +W+QIDEP L +L A+W A Y L Sbjct: 171 EAFNRFDLLNQLVPVYVEILNALVAEGAEWIQIDEPALALDLPAEWVEAYKSVYTELSKV 230 Query: 237 KVKLLLATYFGQLQENGYLAANLPVAGLHVDAIQGREEVTGLLNILPPHKVLSLGVINGR 296 KLLLATYFG + E+ L LPVAGLH+D ++ E++ + KVLS GVI GR Sbjct: 231 NAKLLLATYFGSVAEHAELLKALPVAGLHLDLVRAPEQLAAFEDY---SKVLSAGVIEGR 287 Query: 297 NIWKTDLSALLDWLEPLAQRLGERLWIAPSCSLLHVPVDLAQEEKLDQD---IQSWLAFA 353 NIW+ +L+ +LD LEPL +LGERLWIAPSCSLLH P DL E +L + + SWL+F Sbjct: 288 NIWRANLNKVLDVLEPLKAKLGERLWIAPSCSLLHTPFDLEVEVQLKEKNTALYSWLSFT 347 Query: 354 VQKLDELQLIGRALREGRAAVQDALHANAAALAARRTSPRVHNPAVRAALAQLTPQHGQR 413 +QK++EL ++ +AL GRA+VQ AL A+ A AR TS +H P V LA L QR Sbjct: 348 LQKVEELNVLKQALNNGRASVQAALDASQVAADARATSKEIHRPEVAERLANLPKGADQR 407 Query: 414 NSHYPERASKQAALLQLPLYPTTTIGSFPQTAEIRQARSHYKAGQLDEAAYRTVMRAEIE 473 S + ER KQ A L LPL PTT IGSFPQT EIR AR+ +K G+L A Y M+ EIE Sbjct: 408 KSPFAERIVKQNAWLNLPLLPTTNIGSFPQTTEIRHARASFKKGELSLADYEAAMKKEIE 467 Query: 474 RSVREQEALGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGDI 533 VR QE L LDVLVHGEAERNDMVEYFGE L G+AF++FGWVQSYGSRCVKPP+++GD+ Sbjct: 468 YVVRRQEELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDV 527 Query: 534 SRPQAMTVEWITHAQSLTSKPMKGMLTGPVTLLNWSFVRDDQPRADSCRQLALAIRQEVL 593 +RP+ MTV W +AQSLT++ MKGMLTGPVT+L WSFVR+D PR+ C+Q+ +A+ EVL Sbjct: 528 TRPEPMTVRWSQYAQSLTNRVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVL 587 Query: 594 DLEAAGVRVIQIDEAALREGLPLRRAQWQHYLNWAVQAFRITANGVADTTQIHTHMCYSE 653 DLEAAG++VIQIDE A+REGLPL+RA W YL WA +AFR+++ GV D TQIHTHMCYSE Sbjct: 588 DLEAAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGVQDDTQIHTHMCYSE 647 Query: 654 FNDIIASIADMDADVITIETSRSDMELLDAFDHFNYPNEIGPGVYDIHSPNIPTQEHMVQ 713 FNDI+ +IA +DADVITIETSRSDMELL AF F YPN+IGPGVYDIHSP +PT + Sbjct: 648 FNDILPAIAALDADVITIETSRSDMELLTAFADFKYPNDIGPGVYDIHSPRVPTATEVEH 707 Query: 714 LMQKATERIDARRLWVNPDCGLKTRQWAEVIPALRNMVAAAQTLRA 759 L++KA I RLWVNPDCGLKTR W E I L+ MV + LRA Sbjct: 708 LLRKALNVIPKERLWVNPDCGLKTRGWTETIDQLKVMVDVTKKLRA 753 >NMB0944 [E] COG0620 Methionine synthase II (cobalamin-independent) Nme Neisseria meningitidis MC58 Length = 758 Score = 861 bits (2224), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/767 (55%), Positives = 533/767 (69%), Gaps = 21/767 (2%) Query: 1 MTTIHNLGFPRIGARRELKFALESYWKGESSLAALEETGAQLRRRHWQDQAAL--DLVPV 58 MTT+H GFPR+GA RELKFA E YW+ E S L LR ++W+ Q A D V V Sbjct: 1 MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQVAANADFVAV 60 Query: 59 GDFSFYDQVLDMSVTLGNLPARVQ-DFHGHALDNYFRVARGRSAPHAHDSCCAGVAAGEM 117 GDF+FYD +LD+ V G +PAR D +L+ +F++ARG A EM Sbjct: 61 GDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAI----------EM 110 Query: 118 TKWFDTNYHYIVPEFHATTRFTLDASRLLAQVRQAQEQGVQAKPVIIGPVTYLALGKAKD 177 TKWFDTNYHY+VPEFHA T F +A + Q+++AQ G++AKP ++GP+T+L +GK K Sbjct: 111 TKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKG 170 Query: 178 GS--DKLALLERLLPVYSQLLDTLAAAGVQWVQIDEPILVTELDADWQHALNHAYHHLKV 235 D+L+LL +LLPVY ++L L AG +W+QIDEP L +L +W A Y L Sbjct: 171 AVEFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALAVDLPKEWVEAYKDVYATLSK 230 Query: 236 CKVKLLLATYFGQLQENGYLAANLPVAGLHVDAIQGREEVTGLLNILPPHKVLSLGVING 295 K+LL+TYFG + E+ L LPV GLH+D ++ E++ + KVLS GVI+G Sbjct: 231 VSAKILLSTYFGSVAEHAALLKALPVDGLHIDLVRAPEQLDAFADY---DKVLSAGVIDG 287 Query: 296 RNIWKTDLSALLDWLEPLAQRLGERLWIAPSCSLLHVPVDLAQEEKLDQ---DIQSWLAF 352 RNIW+ +L+ +L+ +EPL +LG+RLWI+ SCSLLH P DL+ EEKL D+ SWLAF Sbjct: 288 RNIWRANLNKVLETVEPLQAKLGDRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAF 347 Query: 353 AVQKLDELQLIGRALREGRAAVQDALHANAAALAARRTSPRVHNPAVRAALAQLTPQHGQ 412 +QK EL+++ AL EGR +V + L A+ AA +R S +H V LA L Q Sbjct: 348 TLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQ 407 Query: 413 RNSHYPERASKQAALLQLPLYPTTTIGSFPQTAEIRQARSHYKAGQLDEAAYRTVMRAEI 472 R S + +R Q A L LPL PTT IGSFPQT EIRQARS +K G+L A Y M+ EI Sbjct: 408 RKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARSAFKKGELSAADYEAAMKKEI 467 Query: 473 ERSVREQEALGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGD 532 V EQE L LDVLVHGEAERNDMVEYFGE L G+AF+Q+GWVQSYGSRCVKPPI+FGD Sbjct: 468 ALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGD 527 Query: 533 ISRPQAMTVEWITHAQSLTSKPMKGMLTGPVTLLNWSFVRDDQPRADSCRQLALAIRQEV 592 +SRP+AMTV W T+AQSLT +PMKGMLTGPVT+L WSFVR+D PR+ C+Q+ALA+ EV Sbjct: 528 VSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEV 587 Query: 593 LDLEAAGVRVIQIDEAALREGLPLRRAQWQHYLNWAVQAFRITANGVADTTQIHTHMCYS 652 LDLE AG++VIQIDE A+REGLPL+RA W YLNWA ++FR+++ G D+TQIHTHMCYS Sbjct: 588 LDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYS 647 Query: 653 EFNDIIASIADMDADVITIETSRSDMELLDAFDHFNYPNEIGPGVYDIHSPNIPTQEHMV 712 EFNDI+ +IA MDADVITIETSRSDMELL AF F YPN+IGPGVYDIHSP +PT+ + Sbjct: 648 EFNDILPAIAAMDADVITIETSRSDMELLTAFGEFQYPNDIGPGVYDIHSPRVPTEAEVE 707 Query: 713 QLMQKATERIDARRLWVNPDCGLKTRQWAEVIPALRNMVAAAQTLRA 759 L++KA E + RLWVNPDCGLKTR W E + L+ M+ + LRA Sbjct: 708 HLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLRA 754 >NMA1140 [E] COG0620 Methionine synthase II (cobalamin-independent) NmA Neisseria meningitidis Z2491 Length = 758 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/767 (55%), Positives = 533/767 (69%), Gaps = 21/767 (2%) Query: 1 MTTIHNLGFPRIGARRELKFALESYWKGESSLAALEETGAQLRRRHWQDQAAL--DLVPV 58 MTT+H GFPR+GA RELKFA E YW+ E S L LR ++W+ QAA D V V Sbjct: 1 MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQAAANADYVAV 60 Query: 59 GDFSFYDQVLDMSVTLGNLPARVQ-DFHGHALDNYFRVARGRSAPHAHDSCCAGVAAGEM 117 GDF+FYD +LD+ V G +PAR D +L+ +F++ARG A EM Sbjct: 61 GDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAI----------EM 110 Query: 118 TKWFDTNYHYIVPEFHATTRFTLDASRLLAQVRQAQEQGVQAKPVIIGPVTYLALGKAKD 177 TKWFDTNYHY+VPEFHA T F +A + Q+++AQ G++AKP ++GP+T+L +GK K Sbjct: 111 TKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKG 170 Query: 178 GS--DKLALLERLLPVYSQLLDTLAAAGVQWVQIDEPILVTELDADWQHALNHAYHHLKV 235 D+L+LL +LLPVY ++L L AG +W+QIDEP L +L +W A Y L Sbjct: 171 AVEFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALTVDLPKEWVEAYKDVYATLSK 230 Query: 236 CKVKLLLATYFGQLQENGYLAANLPVAGLHVDAIQGREEVTGLLNILPPHKVLSLGVING 295 K+LL+TYFG + E+ L +LPV GLH+D ++ E++ + KVLS GVI+G Sbjct: 231 VSAKILLSTYFGSVAEHAALLKSLPVDGLHIDLVRAPEQLDAFADY---DKVLSAGVIDG 287 Query: 296 RNIWKTDLSALLDWLEPLAQRLGERLWIAPSCSLLHVPVDLAQEEKLDQ---DIQSWLAF 352 RNIW+ +L+ +L+ +E L +LG+RLWI+ SCSLLH P DL+ EEKL D+ SWLAF Sbjct: 288 RNIWRANLNKVLETVELLQAKLGDRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAF 347 Query: 353 AVQKLDELQLIGRALREGRAAVQDALHANAAALAARRTSPRVHNPAVRAALAQLTPQHGQ 412 +QK EL+++ AL EGR +V + L A+ AA +R S +H V LA L Q Sbjct: 348 TLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQ 407 Query: 413 RNSHYPERASKQAALLQLPLYPTTTIGSFPQTAEIRQARSHYKAGQLDEAAYRTVMRAEI 472 R S + +R Q A L LPL PTT IGSFPQT EIRQAR+ +K G+L A Y M+ EI Sbjct: 408 RKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAADYEAAMKKEI 467 Query: 473 ERSVREQEALGLDVLVHGEAERNDMVEYFGEQLQGYAFSQFGWVQSYGSRCVKPPILFGD 532 V EQE L LDVLVHGEAERNDMVEYFGE L G+AF+Q+GWVQSYGSRCVKPPI+FGD Sbjct: 468 ALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGD 527 Query: 533 ISRPQAMTVEWITHAQSLTSKPMKGMLTGPVTLLNWSFVRDDQPRADSCRQLALAIRQEV 592 +SRP+AMTV W T+AQSLT +PMKGMLTGPVT+L WSFVR+D PR+ C+Q+ALA+ EV Sbjct: 528 VSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEV 587 Query: 593 LDLEAAGVRVIQIDEAALREGLPLRRAQWQHYLNWAVQAFRITANGVADTTQIHTHMCYS 652 LDLE AG++VIQIDE A+REGLPL+RA W YLNWA ++FR+++ G D+TQIHTHMCYS Sbjct: 588 LDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSTGCEDSTQIHTHMCYS 647 Query: 653 EFNDIIASIADMDADVITIETSRSDMELLDAFDHFNYPNEIGPGVYDIHSPNIPTQEHMV 712 EFNDI+ +IA MDADVITIETSRSDMELL AF F YPN+IGPGVYDIHSP +PT+ + Sbjct: 648 EFNDILPAIAAMDADVITIETSRSDMELLTAFGEFKYPNDIGPGVYDIHSPRVPTEAEVE 707 Query: 713 QLMQKATERIDARRLWVNPDCGLKTRQWAEVIPALRNMVAAAQTLRA 759 L++KA E + RLWVNPDCGLKTR W E + L+ M+ LRA Sbjct: 708 HLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTHKLRA 754