BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.4397.p         (190 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

mlr1523 [S] COG3548 Predicted integral membrane protein Mlo Meso...   167   2e-41
L85237 [S] COG3548 Predicted integral membrane protein Lla Lacto...   117   1e-26
L142704 [S] COG3548 Predicted integral membrane protein Lla Lact...    74   1e-13
L118350 [S] COG3548 Predicted integral membrane protein Lla Lact...    67   2e-11
MTH1490 [S] COG3548 Predicted integral membrane protein Mth Meth...    66   5e-11

>mlr1523 [S] COG3548 Predicted integral membrane protein Mlo Mesorhizobium
           loti
          Length = 246

 Score =  167 bits (422), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 82/187 (43%), Positives = 118/187 (63%)

Query: 1   VNKSRLEAFSDGVIAIAITIMVLGLQTPQGASLDDLAPLMPPLLSYVLSFVYIGIYWVNH 60
           + K R+EAF+DGV+AI ITIMVL L+ P G  +  L PL P   SYVLSF+ +GIYW N 
Sbjct: 56  MGKGRVEAFTDGVVAIIITIMVLELKVPHGEDVSALLPLWPVFFSYVLSFINVGIYWNNL 115

Query: 61  HHLLQLATQVDRRVLWANLHLLFWLSLLPFVTSWVAHHHRQSAPVACYGVVLLMCSVSFL 120
           H++     +VD RVLWANL+LLFWLSL+P  T+++  +H    PVA YG  L +C++++ 
Sbjct: 116 HNMFHTVQRVDGRVLWANLNLLFWLSLMPVTTAFMGENHFAPVPVAVYGADLALCAIAYN 175

Query: 121 LLKLALRHSEAAHPSLAALIGHGRKNALSILLYAVAIPLSLFTPMGATAIYVLLALLWFL 180
           +L  AL        + A  +G+ RK  LS+ +Y  A+ L+        A+YVL+A++W +
Sbjct: 176 ILAAALHRLHGNDTAFAKALGNDRKGKLSLAVYIAAVLLTFVNQWIGVALYVLVAMIWLV 235

Query: 181 PDHHFEQ 187
           PD  F +
Sbjct: 236 PDTRFAR 242


>L85237 [S] COG3548 Predicted integral membrane protein Lla Lactococcus
           lactis
          Length = 188

 Score =  117 bits (294), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 69/188 (36%), Positives = 103/188 (54%), Gaps = 4/188 (2%)

Query: 1   VNKSRLEAFSDGVIAIAITIMVLGLQTPQGASLDDLAPLMPPLLSYVLSFVYIGIYWVNH 60
           ++K+RLEAF+D VIAI +T++VL L  P   SL     L+P L  Y +SF  + IYWVNH
Sbjct: 1   MSKTRLEAFTDAVIAIIMTVLVLELVRPDSDSLQSFIALLPHLGVYFVSFFILAIYWVNH 60

Query: 61  HHLLQLATQVDRRVLWANLHLLFWLSLLPFVTSWVAHHHRQSAPVACYGVVLLMCSVSFL 120
           HHL Q   +++ +VLW N+  LF LSL+P  ++WV+ +     P   Y ++    +  +L
Sbjct: 61  HHLFQSIKRINGKVLWINISFLFVLSLIPIFSNWVSIYPNSFIPELGYVIIFFFGNFIYL 120

Query: 121 LLKLALRHSEAAHPSLAALIGHGRKNALSILLYAVAIPLSLF-TPMGATAIYVLLALLWF 179
           LL   L        +    I   RKN LS++L  V+I L  F  P+       L+  +W 
Sbjct: 121 LLTRELLKINGHRKTSETTI---RKNILSVVLNIVSILLGYFIAPVIMLVGSALIFSMWV 177

Query: 180 LPDHHFEQ 187
           +PD + E+
Sbjct: 178 IPDKNIEK 185


>L142704 [S] COG3548 Predicted integral membrane protein Lla Lactococcus
           lactis
          Length = 183

 Score = 74.3 bits (181), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 47/123 (38%), Positives = 63/123 (51%)

Query: 1   VNKSRLEAFSDGVIAIAITIMVLGLQTPQGASLDDLAPLMPPLLSYVLSFVYIGIYWVNH 60
           + K R  AF+D +IAI  TIMVL  +TP  +    LA L  PLL+Y LSF  I   W NH
Sbjct: 1   MEKERFLAFTDAIIAIIATIMVLEFKTPDKSGWPALAELTIPLLAYALSFFMIMTVWYNH 60

Query: 61  HHLLQLATQVDRRVLWANLHLLFWLSLLPFVTSWVAHHHRQSAPVACYGVVLLMCSVSFL 120
           H L +    +  R+   N   LF +S  PF T WV  H  +  P   Y +V+ + +  F 
Sbjct: 61  HQLYRDIKNITPRIFLLNTLWLFIMSFFPFTTGWVGKHASEFLPEFFYLIVIFLWAAVFH 120

Query: 121 LLK 123
           L+ 
Sbjct: 121 LMD 123


>L118350 [S] COG3548 Predicted integral membrane protein Lla Lactococcus
          lactis
          Length = 203

 Score = 67.0 bits (162), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 59/98 (60%), Gaps = 1/98 (1%)

Query: 1  VNKSRLEAFSDGVIAIAITIMVLGLQTPQ-GASLDDLAPLMPPLLSYVLSFVYIGIYWVN 59
          V+K RL  F D +IA+ +TIM+L  + P+ G  LD L   +  L++Y+LSF+Y+   W N
Sbjct: 2  VSKGRLAGFIDAIIAVIMTIMLLEFELPKTGGILDFLKDNLVYLIAYLLSFIYVTTSWFN 61

Query: 60 HHHLLQLATQVDRRVLWANLHLLFWLSLLPFVTSWVAH 97
            ++L  A ++ RR+  + +  +  LS+LP +++W   
Sbjct: 62 QQYMLSQAEKITRRIYHSCMIWVLSLSMLPVLSAWAGR 99


>MTH1490 [S] COG3548 Predicted integral membrane protein Mth
           Methanothermobacter thermautotrophicus
          Length = 188

 Score = 65.9 bits (159), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 40/110 (36%), Positives = 60/110 (54%), Gaps = 7/110 (6%)

Query: 1   VNKSRLEAFSDGVIAIAITIMVLGLQTPQGA----SLDD-LAPLMPPLLSYVLSFVYIGI 55
           + K RLE   D + AIA+TI+VLG+  P G     ++D  +  L   L SY LSF+ +G+
Sbjct: 4   MKKKRLEGLVDAIFAIAMTILVLGIDVPTGTMSVPAMDAYIMGLASDLYSYCLSFLLLGV 63

Query: 56  Y-WVNHHHLLQLATQVDRRVLWANLHLLFWLSLLPFVTSWVAHHHRQSAP 104
           + WVNH H  +L  +VD   +W N+  L  + L+PF T    ++     P
Sbjct: 64  FWWVNHMHFEKLE-KVDTGFIWINIVWLMVVVLVPFSTKLTGNYGDLVTP 112