BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4374.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO4034_1 [K] COG1609 Transcriptional regulators Ype Yersinia pe... 265 1e-70 ECs4452_1 [K] COG1609 Transcriptional regulators Ecs Escherichia... 258 1e-68 ZxylR_1 [K] COG1609 Transcriptional regulators EcZ Escherichia c... 258 1e-68 xylR_1 [K] COG1609 Transcriptional regulators Eco Escherichia co... 258 1e-68 HI1106_1 [K] COG1609 Transcriptional regulators Hin Haemophilus ... 245 1e-64 >YPO4034_1 [K] COG1609 Transcriptional regulators Ype Yersinia pestis Length = 265 Score = 265 bits (677), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 124/250 (49%), Positives = 168/250 (67%), Gaps = 1/250 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 +RI LLFN NK++DR+++ G+GEY+ +++ +WD+++EEDFRCR I+ W G G+IADFD Sbjct: 6 YRITLLFNANKVYDRQVVEGVGEYLQASQCNWDIFIEEDFRCRIDNIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D L V +P+V +GGSY YP+ Y+ATDN +V A+ HL E GL FA Sbjct: 66 DRQIEQLLANVNVPIVGVGGSYHQSEDYPS-VDYIATDNKALVNAAFMHLKEKGLNRFAF 124 Query: 128 FSLPESPCNRWAQERERIFTDLTGADGITGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LP S RWAQERE F L A+ G +Y+G+ T+ +W A + WV++LP Sbjct: 125 YGLPASCGMRWAQEREYAFRQLVSAEQYQGVVYQGMATAPDNWQYAQNRLADWVQTLPHQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR LLQ C IAVPE++++IGIDN+ L R L+R+ LSSV+QG+ +MG Sbjct: 185 TGIIAVTDARARHLLQVCEHLDIAVPEKLSVIGIDNEELTRYLSRVALSSVVQGTRQMGY 244 Query: 248 TAAHLLHQML 257 AA LLHQ L Sbjct: 245 RAAKLLHQRL 254 >ECs4452_1 [K] COG1609 Transcriptional regulators Ecs Escherichia coli O157:H7 Length = 265 Score = 258 bits (660), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESPCNRWAQERERIFTDLTGADGITGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >ZxylR_1 [K] COG1609 Transcriptional regulators EcZ Escherichia coli O157:H7 EDL933 Length = 265 Score = 258 bits (660), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESPCNRWAQERERIFTDLTGADGITGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >xylR_1 [K] COG1609 Transcriptional regulators Eco Escherichia coli K12 Length = 265 Score = 258 bits (660), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 123/261 (47%), Positives = 170/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 HRI LLFN NK +DR+++ G+GEY+ ++++ WD+++EEDFR R I+ W G G+IADFD Sbjct: 6 HRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 D AL V +P+V +GGSY YP Y+ATDNY +V+ A+ HL E G+ FA Sbjct: 66 DKQIEQALADVDVPIVGVGGSYHLAESYPPVH-YIATDNYALVESAFLHLKEKGVNRFAF 124 Query: 128 FSLPESPCNRWAQERERIFTDLTGADGITGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + LPES RWA ERE F L + G +Y+G+ T+ ++W A + W+++LP Sbjct: 125 YGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQ 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR +LQ C I VPE++ +IGIDN+ L R L+R+ LSSV QG+ +MG Sbjct: 185 TGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L P RI+ Sbjct: 245 QAAKLLHRLLDKEEMPLQRIL 265 >HI1106_1 [K] COG1609 Transcriptional regulators Hin Haemophilus influenzae Length = 265 Score = 245 bits (626), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 116/261 (44%), Positives = 172/261 (65%), Gaps = 1/261 (0%) Query: 8 HRIALLFNGNKIFDREIIAGIGEYISSTRASWDLYLEEDFRCRPQGIERWAGHGIIADFD 67 ++IALLFN NK++DR+++ GIG+YI +++ WD+++E++F I + + GIIADFD Sbjct: 6 YKIALLFNANKVYDRQVVEGIGQYIQASQCMWDIFVEDEFIYHTDTINQLSIDGIIADFD 65 Query: 68 DPVTTAALEGVQLPVVAIGGSYADPSQYPANRPYVATDNYKMVKLAYDHLIEAGLQHFAL 127 DP T L+ +P +A+GGSY YP + PY+ATDN +V++A HL E GL FA Sbjct: 66 DPKTVELLQHTLIPTIAVGGSYKQADFYP-HFPYIATDNMALVEMALSHLQEKGLSQFAF 124 Query: 128 FSLPESPCNRWAQERERIFTDLTGADGITGHIYRGVGTSAQSWDTAVEQQIAWVRSLPKP 187 + L + W+ ER F +L + ++Y GV AQ+W ++ I W++SLP Sbjct: 125 YGLQVNTHKHWSIERRDAFVELMEKNHYPIYLYEGVQVHAQNWLEEQQKLIVWLKSLPSH 184 Query: 188 VGIIAVTDARARQLLQACLFAGIAVPEQVALIGIDNDPLARVLTRIPLSSVIQGSVEMGR 247 GIIAVTDARAR LLQAC ++ IAVPE++ ++GIDN+ L + L+R+ LSSV QG+ E+G Sbjct: 185 TGIIAVTDARARHLLQACEYSKIAVPEELCVVGIDNEELIQYLSRMSLSSVEQGTREIGY 244 Query: 248 TAAHLLHQMLHGARFPDTRIM 268 AA LLH++L+G + T I+ Sbjct: 245 QAAKLLHKLLNGQKVSHTPIL 265