BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4317.p (459 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 217 5e-56 RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 213 5e-55 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 197 4e-50 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 196 8e-50 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 192 2e-48 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 217 bits (552), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 151/412 (36%), Positives = 229/412 (55%), Gaps = 11/412 (2%) Query: 12 VDIGRVLDEGTFTGFQKMVVILAALSIVMDGFDGQLIGFAIPSLIKEWGVTRNAFAPAVA 71 V + V+D + +Q +V+ L + ++DGFD IG+ P+L + W +T APA Sbjct: 10 VPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPAFG 69 Query: 72 AGLVGMGLGSAFAGLFADRFGRRLAIIGSVFVFGIATSLISLSPDITTIAILRFFAGLGI 131 AGL G+ LGS G ADRFGR+ ++ SV VFG+AT + S + T+ +LRF GLG+ Sbjct: 70 AGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGL 129 Query: 132 GGALPVSTTITAEFSPARIRTFAVTATIVCVPLGGMLAGLFANLVLPHYGWRGLFLLGGM 191 GGA+P+ T++AE+SP R R VT + G L GL A +LP YGWRG+ + GG+ Sbjct: 130 GGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGV 189 Query: 192 LPVAFSLLLWFCIPESPRYLARQPDRWDELRSLLTRMS-RTISAGMRF-ADAREQNSQPK 249 P+ +L +PES ++LA++P D LR ++TR++ G+ F D Q P Sbjct: 190 TPLVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIAGHDHGDGVTFIGDRPAQEGAPF 249 Query: 250 AGFGALFAEGRARDTIAIWLAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAANGLTAYNIG 309 G LF++G A+ T+ +W AFF +L Y SWLP ++ +GL+ + AA +G Sbjct: 250 PGRN-LFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVPLG 308 Query: 310 GVFGALLCAVVIGRFGSRVPMLLC--CLAAAGTAFALRSLDVSSQTTLL-VAGIGLHGLF 366 G GA+ A+++ R GS ++ C A A A L +V++ T ++ V G G+ G Sbjct: 309 GTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIAG-- 366 Query: 367 VNAVQCTMYALCAYIYPTQVRATGTAGALAFGRLGAILSAFAGAIVITQGGA 418 Q + L A +YPT+ RATG + AL GR G+I + G ++T G+ Sbjct: 367 ---AQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGS 415 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 213 bits (543), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 145/457 (31%), Positives = 229/457 (50%), Gaps = 20/457 (4%) Query: 6 IDQAKVVDIGRVLDEGTFTGFQKMVVILAALSIVMDGFDGQLIGFAIPSLIKEWGVTRNA 65 + + V+D+ LD F+ FQ VV+L + +DGFD +GF P+L ++W + Sbjct: 2 LPPSPVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAV 61 Query: 66 FAPAVAAGLVGMGLGSAFAGLFADRFGRRLAIIGSVFVFGIATSLISLSPDITTIAILRF 125 +AGL G+ +G+ G ADR GR+ ++ +V FG+A+ L + +P + + LRF Sbjct: 62 LGTVFSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRF 121 Query: 126 FAGLGIGGALPVSTTITAEFSPARIRTFAVTATIVCVPLGGMLAGLFANLVLPHYGWRGL 185 GLG+GGA+P + +T+E+ P R R F T LG G+ A ++P +GWR + Sbjct: 122 LTGLGLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSV 181 Query: 186 FLLGGMLPVAFSLLLWFCIPESPRYLARQPDRWDELRSLLTRMSRT-ISAGMRFA-DARE 243 L GG++P+ ++ F +PES RYL + + + LL R++ ++ RF Sbjct: 182 LLFGGVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETA 241 Query: 244 QNSQPKAGFGALFAEGRARDTIAIWLAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAANGL 303 P + LF T+ +W FFM+LL VY +WLPT++ G++ ++A+ Sbjct: 242 AKGAPGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIA 301 Query: 304 TAYNIGGVFGALLCAVVIGRFGSRVP--MLLCCLAAAGTAFALRSLDVSSQTTLLVAGIG 361 Y +GG GAL VIGR R P ++LCC G F + L SQ T+L + Sbjct: 302 VMYQLGGTVGAL----VIGRMMDRYPATVVLCCTYGLGAGFLV--LTGVSQGTMLAIAVT 355 Query: 362 LHGLFVNAVQCTMYALCAYIYPTQVRATGTAGALAFGRLGAILSAFAGAIVITQGGASGY 421 G ++ Q A A YPT R TG + AL GRLG++ A G +++ Sbjct: 356 GVGFCISGSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLA------- 408 Query: 422 LAMLGGAMLFVFVTL--LMVSKHIPRAAATVKHQEKE 456 A +G +LF+ V + + S I A +H E + Sbjct: 409 -ANIGFQLLFLLVAVPAAIASLAIFLCGAQARHVETQ 444 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 197 bits (501), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 145/451 (32%), Positives = 227/451 (50%), Gaps = 30/451 (6%) Query: 13 DIGRVLDEGTFTGFQKMVVILAALSIVMDGFDGQLIGFAIPSLIKEWGVTRNAFAPAVAA 72 D+ ++D Q V+I L +++DGFD IGF P + W +T AP A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 73 GLVGMGLGSAFAGLFADRFGRRLAIIGSVFVFGIATSLISLSPDITTIAILRFFAGLGIG 132 GL+G+ G+ G +DRFGR+ I VF+FG + + SPD+ T+ LRF GLG+G Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 GALPVSTTITAEFSPARIRTFAVTATIVCVPLGGMLAGLFANLVLPHYGWRGLFLLGGML 192 GA+P + T+T+E+ PAR R VT LG G+ + ++P GW G+ +LGG+L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PVAFSLLLWFCIPESPRYLARQPDRWDELRSLLTRMSRTISAGMRFADAR----EQNSQP 248 P+ + L +PESPR+ R+ + ++ ++R R+ D E S Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRE-----RYVDTHFYLIESASVT 240 Query: 249 KAGFGALFAEGRARDTIAIWLAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAANGLTAYNI 308 K LF + T+ +W+ FFM+LL +Y SW+PT+L G+ A+ A+ I Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 309 GGVFGALLCAVVIGRFGSRVPMLLCCLAAAGTAFALRSLDVSSQTTLLVA------GIGL 362 GG GAL V++ +F P + L+ A A + + +S L+A GIG+ Sbjct: 301 GGTLGALALGVLMDKFN---PFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGI 357 Query: 363 HGLFVNAVQCTMYALCAYIYPTQVRATGTAGALAFGRLGAILSAFAGAIVITQGGASGYL 422 G Q + AL A +YPTQ RATG + + A GR GAI+ + +G +++ + L Sbjct: 358 SG-----SQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTL 412 Query: 423 -------AMLGGAMLFVFVTLLMVSKHIPRA 446 A + ML + +T++ S +P + Sbjct: 413 FFIIAVPAAISAVMLTLLITVVRQSTSVPDS 443 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 196 bits (499), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 143/451 (31%), Positives = 226/451 (50%), Gaps = 30/451 (6%) Query: 13 DIGRVLDEGTFTGFQKMVVILAALSIVMDGFDGQLIGFAIPSLIKEWGVTRNAFAPAVAA 72 D+ ++D Q V+I L +++DGFD IGF P + W +T +P A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 73 GLVGMGLGSAFAGLFADRFGRRLAIIGSVFVFGIATSLISLSPDITTIAILRFFAGLGIG 132 GL+ + G+ G +DRFGR+ I VF+FG + + SPD+ T+ LRF GLG+G Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 GALPVSTTITAEFSPARIRTFAVTATIVCVPLGGMLAGLFANLVLPHYGWRGLFLLGGML 192 GA+P + T+T+E+ PAR R VT LG G+ + ++P GW G+ +LGG+L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PVAFSLLLWFCIPESPRYLARQPDRWDELRSLLTRMSRTISAGMRFADAR----EQNSQP 248 P+ + L +PESPR+ R+ + ++ ++R R+ D E S Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRE-----RYVDTHFYLIESASVT 240 Query: 249 KAGFGALFAEGRARDTIAIWLAFFMNLLAVYSAFSWLPTMLAGEGLSPSVAANGLTAYNI 308 K LF + T+ +W+ FFM+LL +Y SW+PT+L G+ A+ A+ I Sbjct: 241 KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQI 300 Query: 309 GGVFGALLCAVVIGRFGSRVPMLLCCLAAAGTAFALRSLDVSSQTTLLVA------GIGL 362 GG GAL V++ +F P + L+ A A + + +S L+A GIG+ Sbjct: 301 GGTLGALALGVLMDKFN---PFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGI 357 Query: 363 HGLFVNAVQCTMYALCAYIYPTQVRATGTAGALAFGRLGAILSAFAGAIVITQGGASGYL 422 G Q + AL A +YPTQ RATG + + A GR GAI+ + +G +++ + L Sbjct: 358 SG-----SQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTL 412 Query: 423 -------AMLGGAMLFVFVTLLMVSKHIPRA 446 A + ML + +T++ S +P + Sbjct: 413 FFIIAVPAAISAVMLTLLITVVRQSTSVPDS 443 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 192 bits (487), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 139/418 (33%), Positives = 229/418 (54%), Gaps = 5/418 (1%) Query: 1 MSTYGIDQAKVVDIGRVLDEGTFTGFQKMVVILAALSIVMDGFDGQLIGFAIPSLIKEWG 60 M++ + + +D+ ++ + +Q +V+L L + +DG D +GF P+L ++WG Sbjct: 1 MNSPSLPAVERLDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWG 60 Query: 61 VTRNAFAPAVAAGLVGMGLGSAFAGLFADRFGRRLAIIGSVFVFGIATSLISLSPDITTI 120 + R + P ++A L+GM G+ +G ADR+GR+L ++ +VF+FG+ + + S ++ + Sbjct: 61 IDRASLGPVMSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQL 120 Query: 121 AILRFFAGLGIGGALPVSTTITAEFSPARIRTFAVTATIVCVPLGGMLAGLFANLVLPHY 180 LRF GLG+G A+P +TT+ +E++P R+++ VT+ LG G + ++P + Sbjct: 121 LALRFLTGLGLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLF 180 Query: 181 GWRGLFLLGGMLPVAFSLLLWFCIPESPRYLARQPDRWDELRSLLTRMSRTISAGMR-FA 239 GW L LLGG+LP+ +++L F +PES RYL + + +R +L ++ A R F Sbjct: 181 GWHSLLLLGGLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFH 240 Query: 240 DAREQNSQPKAGFGALFAEGRARDTIAIWLAFFMNLLAVYSAFSWLPTMLAGEGLSPSVA 299 +Q Q + F +F+ + T+ +WL +FM L+ VY SWLPT++ G S A Sbjct: 241 VPEQQTVQARNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQA 300 Query: 300 ANGLTAYNIGGVFGALLCAVVIGRFGSRVPMLLCCLAAAGTAFAL-RSLDVSSQTTLLVA 358 A + GGV A+ + RF + L L A A+ + +SL Q TLL Sbjct: 301 AFIGALFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSL---GQVTLLAT 357 Query: 359 GIGLHGLFVNAVQCTMYALCAYIYPTQVRATGTAGALAFGRLGAILSAFAGAIVITQG 416 + L G+ +N Q M +L A YPTQ RATG + L GR GAIL A+ GA ++ G Sbjct: 358 LVLLAGMCINGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLG 415