BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4277.p (467 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 661 0.0 HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 519 e-147 YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 518 e-146 PM1806 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 514 e-145 VC2762 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 511 e-144 >RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Rso Ralstonia solanacearum Length = 455 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/453 (72%), Positives = 375/453 (82%), Gaps = 1/453 (0%) Query: 16 MNIVILAAGMGKRMQSSLPKVLHPLAGKPLLGHVIDTARELAPTQLCVIYGHGGDAVPKA 75 MNIVILAAG+GKRM+S+LPKVLHPLAGKPLL HVI+TAR L+PT+L V+ GHGGD V Sbjct: 1 MNIVILAAGLGKRMRSALPKVLHPLAGKPLLAHVIETARSLSPTRLVVVVGHGGDRVRDM 60 Query: 76 FAGQGLSFALQEPQLGTGHAVMQALPHLDDAAPTLVLYGDVPLTSASSLQRLLVAAGQDK 135 ++FA Q+ QLGTGHAVMQAL LDD PTLVLYGDVPLT A +L L+ AAGQD Sbjct: 61 VGAPDVTFATQDQQLGTGHAVMQALDQLDDTVPTLVLYGDVPLTRAETLNALVGAAGQDH 120 Query: 136 LGVLTVTLDNPTGYGRIVRE-DGRIKRIVEQKDASQAELAIGEVNTGIIVAPTARLRQWL 194 LGVLTV LD+PTGYGRIVR+ GRI RIVEQKDA++ +LAI EVNTGI+V PTARL+ WL Sbjct: 121 LGVLTVHLDDPTGYGRIVRDATGRITRIVEQKDANETQLAIHEVNTGILVCPTARLKTWL 180 Query: 195 AKLSNHNAQGEYYLTDVIAAAVADGVDVVSAQPDDVAETLGVNSKVQLAELERVHQRNIA 254 A L N NAQGEYYLTDVI A ++G+ + SA P ETLGVNSKVQLAELER+HQRN+A Sbjct: 181 ATLRNDNAQGEYYLTDVIERAASEGLPITSAHPLAEWETLGVNSKVQLAELERIHQRNLA 240 Query: 255 HRLLEAGVTLADPARIDVRGSLECARDVSIDVNCVFEGQVSIGEGSTIGAHCVIRNARIA 314 +LLE GVTL DPARID+RG L C RDV ID++C+FEG V++G+G IGAH VIR+A I Sbjct: 241 QQLLEDGVTLIDPARIDIRGRLTCGRDVVIDIDCIFEGNVTLGDGVRIGAHAVIRDAAIQ 300 Query: 315 AGVEIKPFTHIDDAVVGAGGKIGPYARLRPGTELAQDVHIGNFVEVKNSIVGVGSKANHL 374 AG EI PF HI+ A VGA +IGPYARLRPGTELA+DVHIGNFVEVKNS + SKANHL Sbjct: 301 AGAEILPFCHIEQATVGAQSRIGPYARLRPGTELAEDVHIGNFVEVKNSQIAAHSKANHL 360 Query: 375 AYVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDEVFIGSDSQLVAPVRVGKGATIGAG 434 AYVGDA VGS VN+GAG ITCNYDGANKFRTIIED+ FIGSD+QLVAPVRVG+GAT+GAG Sbjct: 361 AYVGDATVGSRVNIGAGTITCNYDGANKFRTIIEDDAFIGSDTQLVAPVRVGRGATLGAG 420 Query: 435 TTLTKDAPAGQLTLSRAKQLSLPGWQRPVKIKK 467 TTLTKDAP GQLT+SRA+Q ++ GWQRPVK KK Sbjct: 421 TTLTKDAPEGQLTVSRARQTTVNGWQRPVKQKK 453 >HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Hin Haemophilus influenzae Length = 456 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 247/451 (54%), Positives = 325/451 (72%) Query: 16 MNIVILAAGMGKRMQSSLPKVLHPLAGKPLLGHVIDTARELAPTQLCVIYGHGGDAVPKA 75 ++ VILAAG G RM S LPKVLH +AGKP++ HVIDTA +L + +IYGHGGD + Sbjct: 6 LSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTH 65 Query: 76 FAGQGLSFALQEPQLGTGHAVMQALPHLDDAAPTLVLYGDVPLTSASSLQRLLVAAGQDK 135 A + +++ LQ QLGT HAV QA P D +VLYGD PL + +L++L+ A ++ Sbjct: 66 LANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENG 125 Query: 136 LGVLTVTLDNPTGYGRIVREDGRIKRIVEQKDASQAELAIGEVNTGIIVAPTARLRQWLA 195 + +LTV LDNPTGYGRI+RE+G + IVEQKDA+ +L I EVNTG++V+ A ++WLA Sbjct: 126 IALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLA 185 Query: 196 KLSNHNAQGEYYLTDVIAAAVADGVDVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 255 ++ N+NAQGEYYLTD+IA A D VV+ Q DV E G N+++QLA LER Q A Sbjct: 186 RVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQAS 245 Query: 256 RLLEAGVTLADPARIDVRGSLECARDVSIDVNCVFEGQVSIGEGSTIGAHCVIRNARIAA 315 +LL GV + DPAR D+RG+LE +DV IDVN + EG V +G+ IG CV++N I Sbjct: 246 KLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGN 305 Query: 316 GVEIKPFTHIDDAVVGAGGKIGPYARLRPGTELAQDVHIGNFVEVKNSIVGVGSKANHLA 375 VEIKP++ ++D++VG IGP++RLRPG ELA + H+GNFVE+K S VG GSK NHL Sbjct: 306 DVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLT 365 Query: 376 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDEVFIGSDSQLVAPVRVGKGATIGAGT 435 YVGD+++GS N+GAGVITCNYDGANKF+TII D+VF+GSD+QLVAPV+V GATIGAGT Sbjct: 366 YVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGT 425 Query: 436 TLTKDAPAGQLTLSRAKQLSLPGWQRPVKIK 466 T+T+D +L ++R Q + GWQRP+K K Sbjct: 426 TITRDVGENELVITRVAQRHIQGWQRPIKKK 456 >YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Ype Yersinia pestis Length = 456 Score = 518 bits (1333), Expect = e-146, Method: Compositional matrix adjust. Identities = 252/451 (55%), Positives = 329/451 (72%) Query: 16 MNIVILAAGMGKRMQSSLPKVLHPLAGKPLLGHVIDTARELAPTQLCVIYGHGGDAVPKA 75 M++VILAAG G RM S LPKVLHPLAGKP++ HVID A +L + ++YGHGG+ + K Sbjct: 6 MSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKT 65 Query: 76 FAGQGLSFALQEPQLGTGHAVMQALPHLDDAAPTLVLYGDVPLTSASSLQRLLVAAGQDK 135 A L++ LQ QLGTGHA+ QA PH D L+LYGDVPL S +LQRLL A + Sbjct: 66 LADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGG 125 Query: 136 LGVLTVTLDNPTGYGRIVREDGRIKRIVEQKDASQAELAIGEVNTGIIVAPTARLRQWLA 195 +G+LTV LDNP+GYGRIVRE+G + IVE KDAS A+ I E+NTGI+VA L++WL+ Sbjct: 126 IGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLS 185 Query: 196 KLSNHNAQGEYYLTDVIAAAVADGVDVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 255 L N+NAQGE+Y+TD+IA A ADG + + P ++E GVN+++QL+ LERV Q A Sbjct: 186 LLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAE 245 Query: 256 RLLEAGVTLADPARIDVRGSLECARDVSIDVNCVFEGQVSIGEGSTIGAHCVIRNARIAA 315 +LL AGV L DP+R D+RG L RD++ID N + EG V +G+ IG CV++N I Sbjct: 246 KLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGD 305 Query: 316 GVEIKPFTHIDDAVVGAGGKIGPYARLRPGTELAQDVHIGNFVEVKNSIVGVGSKANHLA 375 EI P+T ++DA + A +GP+ARLRPG ELA+ H+GNFVE+K + +G GSKA HL+ Sbjct: 306 DSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLS 365 Query: 376 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDEVFIGSDSQLVAPVRVGKGATIGAGT 435 Y+GDA++G+GVN+GAG ITCNYDGANKF+TII D+VF+GSD+QLVAPV V GATIGAGT Sbjct: 366 YLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGT 425 Query: 436 TLTKDAPAGQLTLSRAKQLSLPGWQRPVKIK 466 T+T+D +L +SR KQ+ + GW+RPVK K Sbjct: 426 TVTRDVAENELVISRVKQVHIQGWKRPVKKK 456 >PM1806 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Pmu Pasteurella multocida Length = 458 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 251/452 (55%), Positives = 325/452 (71%) Query: 16 MNIVILAAGMGKRMQSSLPKVLHPLAGKPLLGHVIDTARELAPTQLCVIYGHGGDAVPKA 75 ++IVILAAG G RM S LPKVLH +AGKP++ HVIDT + + + ++YGHGG+ + Sbjct: 6 LSIVILAAGKGTRMYSDLPKVLHKIAGKPMVKHVIDTVKSIHAKNIHLVYGHGGEVMQTR 65 Query: 76 FAGQGLSFALQEPQLGTGHAVMQALPHLDDAAPTLVLYGDVPLTSASSLQRLLVAAGQDK 135 + +++ LQ QLGTGHA+ QA P D L+LYGD PL +A +LQ L+ A + Sbjct: 66 LQDEPVNWVLQAEQLGTGHAMQQAAPFFADDENILMLYGDGPLITAETLQTLIAAKPEHG 125 Query: 136 LGVLTVTLDNPTGYGRIVREDGRIKRIVEQKDASQAELAIGEVNTGIIVAPTARLRQWLA 195 + +LTV LD+PTGYGRIVRE+G + IVEQKDA+ +L I E+NTG++VA L++WL+ Sbjct: 126 IALLTVVLDDPTGYGRIVRENGNVVAIVEQKDANAEQLKIQEINTGLLVADGKSLKKWLS 185 Query: 196 KLSNHNAQGEYYLTDVIAAAVADGVDVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 255 +L+N+NAQGEYY+TDVIA A DG VV+ Q D E GVN++ QLA LER +QR A Sbjct: 186 QLTNNNAQGEYYITDVIALANQDGCQVVAVQASDFMEVEGVNNRQQLARLERYYQRKQAD 245 Query: 256 RLLEAGVTLADPARIDVRGSLECARDVSIDVNCVFEGQVSIGEGSTIGAHCVIRNARIAA 315 LL AGV LADP R D+RG L +DV IDVN + EG+VS+G IGA CV++N +I Sbjct: 246 NLLLAGVALADPERFDLRGELSHGKDVEIDVNVIIEGKVSLGHRVKIGAGCVLKNCQIGD 305 Query: 316 GVEIKPFTHIDDAVVGAGGKIGPYARLRPGTELAQDVHIGNFVEVKNSIVGVGSKANHLA 375 VEIKP++ +++A+VG +IGP++RLRPGT LA + HIGNFVE+K + +G GSK NHL+ Sbjct: 306 DVEIKPYSVLEEAIVGQAAQIGPFSRLRPGTALADNTHIGNFVEIKKAHIGTGSKVNHLS 365 Query: 376 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDEVFIGSDSQLVAPVRVGKGATIGAGT 435 YVGDA+VG N+GAGVITCNYDGANKF+TII D VF+GSD QLVAPV + GATIGAGT Sbjct: 366 YVGDAEVGMQCNIGAGVITCNYDGANKFKTIIGDNVFVGSDVQLVAPVTIETGATIGAGT 425 Query: 436 TLTKDAPAGQLTLSRAKQLSLPGWQRPVKIKK 467 T+TKD +L +SR Q + GWQRP K K Sbjct: 426 TVTKDVACDELVISRVPQRHIQGWQRPTKQTK 457 >VC2762 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Vch Vibrio cholerae Length = 453 Score = 511 bits (1317), Expect = e-144, Method: Compositional matrix adjust. Identities = 253/451 (56%), Positives = 321/451 (71%) Query: 16 MNIVILAAGMGKRMQSSLPKVLHPLAGKPLLGHVIDTARELAPTQLCVIYGHGGDAVPKA 75 + VILAAG G RM S++PKVLH LAGKP++ HVIDT L + ++YGHGGD + +A Sbjct: 3 FSTVILAAGKGTRMHSNMPKVLHTLAGKPMVKHVIDTCNNLGAQNIHLVYGHGGDQMQQA 62 Query: 76 FAGQGLSFALQEPQLGTGHAVMQALPHLDDAAPTLVLYGDVPLTSASSLQRLLVAAGQDK 135 A + +++ LQ QLGTGHAV QA PH D LVLYGDVPL S +++ LL A D Sbjct: 63 LANENVNWVLQAQQLGTGHAVDQASPHFQDDEKILVLYGDVPLISEDTIESLLEAQPTDG 122 Query: 136 LGVLTVTLDNPTGYGRIVREDGRIKRIVEQKDASQAELAIGEVNTGIIVAPTARLRQWLA 195 + +LTV L++PTGYGRIVR+ G + IVEQKDAS+ + I EVNTG++VA L++WLA Sbjct: 123 IALLTVVLEDPTGYGRIVRKRGPVVAIVEQKDASEEQKLIKEVNTGVLVATGRDLKRWLA 182 Query: 196 KLSNHNAQGEYYLTDVIAAAVADGVDVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 255 L+N+NAQGEYYLTDVIAAA +G V + P E GVN ++QLA LER Q A Sbjct: 183 GLNNNNAQGEYYLTDVIAAAHDEGRAVEAVHPSHSIEVEGVNDRIQLARLERAFQARQAK 242 Query: 256 RLLEAGVTLADPARIDVRGSLECARDVSIDVNCVFEGQVSIGEGSTIGAHCVIRNARIAA 315 +LLE GV L DPAR D+RG+L+C DV IDVN + EG VSIG IGA ++++ I Sbjct: 243 KLLEQGVMLRDPARFDLRGTLQCGSDVEIDVNVIIEGNVSIGNNVVIGAGSILKDCEIDD 302 Query: 316 GVEIKPFTHIDDAVVGAGGKIGPYARLRPGTELAQDVHIGNFVEVKNSIVGVGSKANHLA 375 I+P++ I+ A VG +GP+ RLRPG EL D H+GNFVE+KN+ +G GSKANHL Sbjct: 303 NTVIRPYSVIEGATVGENCTVGPFTRLRPGAELRDDAHVGNFVEMKNARLGEGSKANHLT 362 Query: 376 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDEVFIGSDSQLVAPVRVGKGATIGAGT 435 Y+GDA++G GVNVGAGVITCNYDGANK +T+I D+VF+GSD QLVAPV +G GATIGAGT Sbjct: 363 YLGDAEIGKGVNVGAGVITCNYDGANKHKTVIGDDVFVGSDCQLVAPVTIGNGATIGAGT 422 Query: 436 TLTKDAPAGQLTLSRAKQLSLPGWQRPVKIK 466 TLTK+ G+L ++RA + + GWQRP K K Sbjct: 423 TLTKNVAEGELVITRAPERKIAGWQRPAKKK 453