BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4268.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0156 [IQR] COG1028 Dehydrogenases with different specificitie... 295 1e-79 CC0417 [IQR] COG1028 Dehydrogenases with different specificities... 211 1e-54 BMEI1250 [IQR] COG1028 Dehydrogenases with different specificiti... 176 5e-44 mlr7910 [IQR] COG1028 Dehydrogenases with different specificitie... 170 3e-42 AGc2091 [IQR] COG1028 Dehydrogenases with different specificitie... 164 2e-40 >RSc0156 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 267 Score = 295 bits (754), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 161/260 (61%), Positives = 190/260 (73%), Gaps = 7/260 (2%) Query: 8 SPSSAGVALVTGAARRIGRHIALALAQAGWDVAVHYNRSRQEAEELVREIEDLGRRALAV 67 SP +ALVTGAARR+GR IALALA+ GWDVAVH +RSR EA+ + EI +GRRA + Sbjct: 8 SPILPRIALVTGAARRVGRVIALALARQGWDVAVHCHRSRAEADAVAAEIIAMGRRAAVL 67 Query: 68 QGELGDQAQVRALLPQA-APLGRISCVVNNASLFDYDDAASFGNDRLLRHMSANVGAPVL 126 Q +L D+A L+ A LG +C+VNNASLF YD A SF L HM NV AP+L Sbjct: 68 QADLADEAAAGRLIADCTAALGTPTCLVNNASLFQYDVATSFSYASLDTHMRINVAAPLL 127 Query: 127 LAQALFEITPA-----GE-QAVVVNLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALA 180 LA+ L + A GE + VVVNLLDQKL N NPDFLSYTLSKAAL +ATT LAQALA Sbjct: 128 LARELHRVLAAEDGGAGEVRGVVVNLLDQKLDNLNPDFLSYTLSKAALATATTQLAQALA 187 Query: 181 PKVRVVGVAPGLTMVSGDQTEEQFGKAHTVTPLGRGSTPEDIAAAVCYVASARAVTGTTL 240 P +RVVGVAPG T+VS Q+E F +AH + PLGR STPEDIA AVCY+ +ARAVTGTTL Sbjct: 188 PTLRVVGVAPGATLVSWKQSESGFERAHKMAPLGRSSTPEDIAEAVCYLTTARAVTGTTL 247 Query: 241 LVDGGQHLLPLSRDVMFVAK 260 VDGGQHL+PL+RDVMF+ + Sbjct: 248 FVDGGQHLMPLARDVMFLTE 267 >CC0417 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 250 Score = 211 bits (537), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 116/239 (48%), Positives = 158/239 (66%) Query: 10 SSAGVALVTGAARRIGRHIALALAQAGWDVAVHYNRSRQEAEELVREIEDLGRRALAVQG 69 +S G ALVTGA RRIG+ +AL A+AG+DVA+HY S EAEE R + DL RRAL V+ Sbjct: 2 TSRGAALVTGAGRRIGQVLALEAARAGYDVAIHYRASADEAEETARAVRDLDRRALLVRA 61 Query: 70 ELGDQAQVRALLPQAAPLGRISCVVNNASLFDYDDAASFGNDRLLRHMSANVGAPVLLAQ 129 +L D+ + R+L+ QAAPLG ++ ++NNAS F+ D RH+ N+ AP++LA+ Sbjct: 62 DLSDEDETRSLVAQAAPLGPLTLLINNASAFEDDRVGGLSRASWDRHLETNLRAPIVLAE 121 Query: 130 ALFEITPAGEQAVVVNLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVA 189 A+ PA Q +VVNL+DQ+++ PNP F SYTLSKA L AT LAQALAP++RV + Sbjct: 122 AMAAALPADRQGLVVNLIDQRVWRPNPQFFSYTLSKAGLWWATQTLAQALAPRIRVNAIG 181 Query: 190 PGLTMVSGDQTEEQFGKAHTVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHL 248 PG T+ S Q +F L R ++PE++AAA+ Y+ A +VTG + VDGGQHL Sbjct: 182 PGPTLPSVHQAPGEFEAEAAGVLLQRRASPEEVAAALRYLIDASSVTGQMIAVDGGQHL 240 >BMEI1250 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 281 Score = 176 bits (446), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 100/234 (42%), Positives = 137/234 (58%), Gaps = 3/234 (1%) Query: 16 LVTGAARRIGRHIALALAQAGWDVAVHYNRSRQEAEELVREIEDLGRRALAVQGELGDQA 75 LVTG ARRIG+ I LA G+ VA+H NRS E E +V I D G A VQ +L + Sbjct: 38 LVTGGARRIGKAIVEDLASHGFPVAIHCNRSLDEGEAIVNRINDSGGNACVVQADL--EG 95 Query: 76 QVRALLPQAAP-LGRISCVVNNASLFDYDDAASFGNDRLLRHMSANVGAPVLLAQALFEI 134 VR L+ QA+ +G I +VNNASLF D + RH + ++ PV+LA+ + + Sbjct: 96 DVRGLVKQASDRIGPIRLLVNNASLFQEDKVGALDMALWDRHFAVHLKTPVILAEDMPKA 155 Query: 135 TPAGEQAVVVNLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVAPGLTM 194 P + +VVN++DQ+++ NP F SYTLSK AL +AT LAQALAP++RV +APG T+ Sbjct: 156 LPEDQDGLVVNIIDQRVWKLNPQFFSYTLSKTALWNATRTLAQALAPRIRVNAIAPGPTL 215 Query: 195 VSGDQTEEQFGKAHTVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHL 248 S Q E F + + PL R + V Y R++TG + +DGGQHL Sbjct: 216 PSERQRPEDFERQVSKLPLQRAPELPEFGRTVRYFWENRSITGQMIALDGGQHL 269 >mlr7910 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 254 Score = 170 bits (431), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 101/242 (41%), Positives = 138/242 (57%), Gaps = 1/242 (0%) Query: 15 ALVTGAARRIGRHIALALAQAGWDVAVHYNRSRQEAEELVREIEDLGRRALAVQGELGDQ 74 ALVTG A+RIG+ I LA G+ VA+H NRS+ EA+ L I G RA V +L D Sbjct: 8 ALVTGGAKRIGKAIVEDLAGHGFAVAIHANRSQGEADALAAGINQSGGRATVVGADLTDT 67 Query: 75 AQVRALLPQA-APLGRISCVVNNASLFDYDDAASFGNDRLLRHMSANVGAPVLLAQALFE 133 V L+ QA A LG IS +VNNASLF D F RH + +V P LLA+ Sbjct: 68 NAVAGLVGQAEAALGPISLLVNNASLFVDDSIEDFDWQAWDRHFAIHVKTPALLARNFAR 127 Query: 134 ITPAGEQAVVVNLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVAPGLT 193 P G + ++VN++DQ+++ P P + SY LSK+AL + T +LAQAL P++RV + PG T Sbjct: 128 ALPEGREGLIVNIIDQRVWRPTPRYFSYALSKSALWTQTQMLAQALGPRIRVNAIGPGPT 187 Query: 194 MVSGDQTEEQFGKAHTVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHLLPLSR 253 + + Q + F L RG + A + Y+ AR+VTG + +DGGQHL + Sbjct: 188 LKNVRQDDSDFDAQLAGLILKRGPELPEFGATIRYLWDARSVTGQMIALDGGQHLAWQTP 247 Query: 254 DV 255 DV Sbjct: 248 DV 249 >AGc2091 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 277 Score = 164 bits (414), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 98/234 (41%), Positives = 134/234 (57%), Gaps = 1/234 (0%) Query: 16 LVTGAARRIGRHIALALAQAGWDVAVHYNRSRQEAEELVREIEDLGRRALAVQGELGDQA 75 L+TGAARR+GR IA LA G+ +AVH N S +AEE EI G RA AVQ +L A Sbjct: 32 LITGAARRLGRAIASDLAAHGFAIAVHANESMAQAEEFANEIRQKGGRATAVQADLTQSA 91 Query: 76 QVRALLPQAAP-LGRISCVVNNASLFDYDDAASFGNDRLLRHMSANVGAPVLLAQALFEI 134 AL+ +AA LG I VVNNAS+F D A + H + +V AP L+A A E Sbjct: 92 PTMALVEKAAAALGPIGVVVNNASVFLADTAETPDPAVFDAHFAVHVRAPSLIAAAFVEQ 151 Query: 135 TPAGEQAVVVNLLDQKLYNPNPDFLSYTLSKAALHSATTLLAQALAPKVRVVGVAPGLTM 194 PA + ++VN++DQ++ P F SYTLSK+ L +AT +AQ+ AP+VRV + PG T Sbjct: 152 LPAEKSGLIVNIIDQRVLALTPRFYSYTLSKSTLWTATRTMAQSFAPRVRVNAIGPGPTF 211 Query: 195 VSGDQTEEQFGKAHTVTPLGRGSTPEDIAAAVCYVASARAVTGTTLLVDGGQHL 248 S Q + F L RG P++ + ++ ++TG + +DGGQHL Sbjct: 212 KSERQAPQDFQAQIDGLILKRGPAPDEFGRTIRFLYDTPSITGQMIALDGGQHL 265