BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4244.p (275 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermot... 247 2e-65 FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobac... 221 1e-57 TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermo... 213 4e-55 AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agroba... 212 7e-55 MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methano... 204 2e-52 >TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermotoga maritima Length = 286 Score = 247 bits (631), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 122/272 (44%), Positives = 174/272 (63%), Gaps = 4/272 (1%) Query: 4 DITSLKTIASQLRGRIIDNAHRTQTPHLGSCLSCVDILTAAYFSTLRIDPSQPADPLRDR 63 ++ LK A ++R I+D ++ ++ H G LS V+IL ++ LR+ P P RDR Sbjct: 8 EVLELKRKAIEIRKMILDMIYKAKSGHTGGSLSSVEILVTLFYKILRVKPEDPNWEDRDR 67 Query: 64 FILSKGHGAAALFQVLALRGFYPQSLLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHG 123 FILSKGH A + VLA +GF+P+ L+ Y K G HP +PG+E TG+LGHG Sbjct: 68 FILSKGHSVEAYYAVLADKGFFPKEELETYCKYGSRLTGHPTRK--VPGVEVNTGALGHG 125 Query: 124 LPIGLGMALAGRIQQRRYDVTVLLGDGECNEGSVWEAAMMAAAQRVGNLMVLVDFNKWQA 183 L IG+GMALAG++ + Y V VL+GDGE +EGSVWEAA +A+ + NL+ +VD N+ Q Sbjct: 126 LAIGVGMALAGKMDGKDYKVYVLMGDGELDEGSVWEAAQVASHYSLDNLIGIVDRNRLQI 185 Query: 184 TGRSEEVLALNPLVDKWRAFGWDATEIDGHDMSTLVE-LMGRPRAADSKPIAVVAHTIKG 242 +G +EEVL L PL +W AFGW+ E+DGHD +L + + PR KP ++A+TIKG Sbjct: 186 SGHTEEVLKLEPLSKRWEAFGWNVLEVDGHDFESLYKTFVSIPRET-GKPHLIIANTIKG 244 Query: 243 KGVSFMEDDNNWHYRIPNADEVAAAYQELGVQ 274 KG+SF+E WH+++P+ +E A +EL Q Sbjct: 245 KGISFIEGRVEWHHKVPSDEEYRKAIEELEEQ 276 >FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobacterium nucleatum Length = 270 Score = 221 bits (564), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 114/268 (42%), Positives = 152/268 (56%), Gaps = 1/268 (0%) Query: 4 DITSLKTIASQLRGRIIDNAHRTQTPHLGSCLSCVDILTAAYFSTLRIDPSQPADPLRDR 63 DI+ LK A ++R I+ ++ H G LS DILTA YFS + +DP+ P RDR Sbjct: 3 DISFLKEKAKEIRKSIVSMIAEAKSGHPGGSLSATDILTALYFSEMNVDPTNPKMEGRDR 62 Query: 64 FILSKGHGAAALFQVLALRGFYPQSLLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHG 123 F+LSKGH A A++ LA +G++ + L K G HP L GIE +TGSLG G Sbjct: 63 FVLSKGHAAPAIYATLAEKGYFSKDELMTLRKFGSRLQGHPDMK-KLSGIEISTGSLGQG 121 Query: 124 LPIGLGMALAGRIQQRRYDVTVLLGDGECNEGSVWEAAMMAAAQRVGNLMVLVDFNKWQA 183 L + GMAL +I Y V+LGDGE EG +WEAAM AA ++ NL +D N Q Sbjct: 122 LSVANGMALNAKIFDENYRTYVVLGDGEIQEGQIWEAAMTAAHYKLDNLCAFLDSNNLQI 181 Query: 184 TGRSEEVLALNPLVDKWRAFGWDATEIDGHDMSTLVELMGRPRAADSKPIAVVAHTIKGK 243 G E+ + PL KW AFGW+ +IDGHD ++ + + R KP ++A TIKGK Sbjct: 182 DGNVTEIKGVEPLDKKWEAFGWNVIKIDGHDFEQILSALEKARECKGKPTMIIAKTIKGK 241 Query: 244 GVSFMEDDNNWHYRIPNADEVAAAYQEL 271 GVSFME+ +H P +E+ A EL Sbjct: 242 GVSFMENVCGFHGVAPTVEELERALAEL 269 >TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermoplasma volcanium Length = 273 Score = 213 bits (541), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 110/268 (41%), Positives = 162/268 (60%), Gaps = 4/268 (1%) Query: 8 LKTIASQLRGRIIDNAHRTQTPHLGSCLSCVDILTAAYFSTLRIDPSQPADPLRDRFILS 67 L IA ++R II + Q+ H G LS DILT YF + IDP++P DP RDR ILS Sbjct: 8 LSDIALKIRREIIRMVYNAQSGHPGGSLSVTDILTVLYFKEMNIDPNKPKDPKRDRLILS 67 Query: 68 KGHGAAALFQVLALRGFYPQSLLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHGLPIG 127 KGH + AL+ LA+RGF+P S L + K H +PG+E +TGSLG GL IG Sbjct: 68 KGHASPALYATLAIRGFFPVSDLSGFRKLDSHLEGH--VTREVPGVEVSTGSLGQGLGIG 125 Query: 128 LGMALAGRIQQRRYDVTVLLGDGECNEGSVWEAAMMAAAQRVGNLMVLVDFNKWQATGRS 187 +GMALAGR+ +Y V V+LGDGE EG+VWE+ M + N+ ++D N Q G + Sbjct: 126 VGMALAGRLDGMQYRVYVILGDGEMEEGNVWESLMAGYKYNLNNITAILDKNGIQLDGYT 185 Query: 188 EEVLALNPLVDKWRAFGWDATEIDGHDMSTLVELMGRPRAADSKPIAVVAHTIKGKGVSF 247 ++++ ++ + +FGW+ EIDGH+ + E + + +D +P ++A+T+KGKGV F Sbjct: 186 KDIMPMHDIKSMVESFGWNVIEIDGHNYDQIHEAVQASKNSD-RPTFIIANTVKGKGVDF 244 Query: 248 MEDDNNWHYRIPNADEV-AAAYQELGVQ 274 ME++ +H P + E+ A ++LG Q Sbjct: 245 MENNPKYHGSPPESKELFERAMKQLGEQ 272 >AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 269 Score = 212 bits (540), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 107/265 (40%), Positives = 158/265 (59%), Gaps = 4/265 (1%) Query: 7 SLKTIASQLRGRIIDNAHRTQTPHLGSCLSCVDILTAAYFSTLRIDPSQPADPLRDRFIL 66 L+ IA Q+R R + H+G +S +DI+TA YF LRI P+ P +P RDRF+L Sbjct: 5 ELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVL 64 Query: 67 SKGHGAAALFQVLALRGFYPQSLLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHGLPI 126 SKGH A AL+ LA RGF P+ + + + HP + +PG+E TG LGHGLP+ Sbjct: 65 SKGHTACALYVTLAKRGFIPEEEISTFLQPNSRLNGHPNC-NKVPGVETNTGPLGHGLPV 123 Query: 127 GLGMALAGRIQQRRYDVTVLLGDGECNEGSVWEAAMMAAAQRVGNLMVLVDFNKWQATGR 186 +GMA A ++ Y V+ GDGE EGS WEA M AA ++ NL +++D N++Q Sbjct: 124 AVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMSAAQFKLNNLTLVIDHNRFQQGAA 183 Query: 187 SEEVLALNPLVDKWRAFGWDATEIDGHDMSTLVELMGRPRAADSKPIAVVAHTIKGKGVS 246 + + PL K AFGW+ TEI+G+ M+ +V + ++P +VAHT KG G+S Sbjct: 184 IADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPAL---EHRGNRPHCIVAHTNKGHGIS 240 Query: 247 FMEDDNNWHYRIPNADEVAAAYQEL 271 FM+D +WH+++P+ ++ A +EL Sbjct: 241 FMQDRVDWHHKVPSKEQYEIAVKEL 265 >MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methanococcus jannaschii Length = 274 Score = 204 bits (519), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 109/269 (40%), Positives = 157/269 (58%), Gaps = 3/269 (1%) Query: 4 DITSLKTIASQLRGRIIDNAHRTQTPHLGSCLSCVDILTAAYFSTLRIDPSQPADPLRDR 63 +I L+ IA ++R I+ ++ H G LS DI+ A YF + P P RDR Sbjct: 6 EIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYKKDRDR 65 Query: 64 FILSKGHGAAALFQVLALRGFYPQSLLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHG 123 F+LSKGH A AL+ VL+ G + L + G HP PG+E TGSLG G Sbjct: 66 FVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKLQGHPSMDT--PGVEICTGSLGQG 123 Query: 124 LPIGLGMALAGRIQQRRYDVTVLLGDGECNEGSVWEAAMMAAAQRVGNLMVLVDFNKWQA 183 +GMAL R+ + V VLLGDGEC EG VWEAAM AA ++ NL+ +D NK Q Sbjct: 124 FSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRNKLQI 183 Query: 184 TGRSEEVLALNPLVDKWRAFGWDATEIDGHDMSTLVELMGRPRA-ADSKPIAVVAHTIKG 242 G +E+V++L + K+ AFGWD EIDGH+ ++ + + ++ + KP ++A+T+KG Sbjct: 184 DGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYTVKG 243 Query: 243 KGVSFMEDDNNWHYRIPNADEVAAAYQEL 271 KGVSFME++ +H + PN +++ A +EL Sbjct: 244 KGVSFMENNVAFHGKAPNEEQLKQALEEL 272