BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4241.p (316 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl161 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu ... 170 3e-42 BMEII0832 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases B... 157 3e-38 SMb21060 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sm... 142 1e-33 Cj1427c [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Cje... 142 1e-33 sll0576 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Syn... 140 4e-33 >AGl161 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 378 Score = 170 bits (431), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 105/311 (33%), Positives = 171/311 (54%), Gaps = 18/311 (5%) Query: 1 MNILVTGGCGYKGSVLVPKLLARGYKVHVLDIMWFGNYL----APHPNLTVTAGDVRNID 56 M++LVTG GY GSV+VP L G+ VH D ++ P P + D+R+I Sbjct: 23 MHVLVTGHRGYIGSVMVPILRKAGHDVHGYDTEFYHRCAYVPGGPLPQVPGVCKDIRDIT 82 Query: 57 QINLDGVDTIIHLSSVANDPCGDLDPKLTWEVSALATMQLADKAVRKGVKQFIYASSGSV 116 +++G D +IHL++++NDP +L+P++T+E++ +++ A A + GVK+FI+ASS S Sbjct: 83 PADMEGFDAVIHLAALSNDPLSNLNPEITYEINYRGSVRAAQAAKQAGVKRFIFASSCSN 142 Query: 117 YGVKEELQVTEDLELKPISEYNKTKMVSEPVLLSYKDRMIVQI-VRPATVCGYSPRMRLD 175 YG E V E ELKP+S Y +K+++E + S + +RPAT G SP +R D Sbjct: 143 YGAAGEGLVNETAELKPVSAYGTSKVLAEREIASLASPGFSPVYMRPATAYGLSPMLRFD 202 Query: 176 VSVNLLTMQALAKGKITVFG-GTQVRPNIHIDDITDVYLHLIDHPEITGVYNAGF----- 229 + +N LT A+ +G I + G+ RP +HI+DI+ +L ++ P ++N F Sbjct: 203 IVLNNLTAWAVTEGLILLKSDGSPWRPIVHIEDISRAFLAALEAP-TDAIHNQAFNVGQD 261 Query: 230 -ENISILDIAKMVAKHIP---VDIVVTESNDPRSYRVNSDKLLAT--GFKPSKSVETAIT 283 N I +IA++VA +P + S D RSYRV+ K+ FKP+ + Sbjct: 262 AHNYQIREIAEIVALTVPGCRLQYASDASPDTRSYRVDFGKIARALPAFKPTWTAAAGAE 321 Query: 284 EIIEKFQSGVL 294 ++ ++S L Sbjct: 322 QLYRAYKSAGL 332 >BMEII0832 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Bme Brucella melitensis Length = 355 Score = 157 bits (398), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 104/315 (33%), Positives = 167/315 (53%), Gaps = 18/315 (5%) Query: 1 MNILVTGGCGYKGSVLVPKLLARGYKVHVLDIMWFGNYLAPHP----NLTVTAGDVRNID 56 M +LVTG GY GSV+VP L+ G++V DI + + L N+ DVR++ Sbjct: 3 MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVS 62 Query: 57 QINLDGVDTIIHLSSVANDPCGDLDPKLTWEVSALATMQLADKAVRKGVKQFIYASSGSV 116 +L+G D +IHL++++NDP G+L+ LT+ ++ A++ +A A GV +F++ASS S Sbjct: 63 PRDLEGFDAVIHLAALSNDPLGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSN 122 Query: 117 YGVKEELQVTEDLELKPISEYNKTKMVSEPVLLSYKDRMIVQI-VRPATVCGYSPRMRLD 175 YG+ + + E ELKP++ Y ++K+ +E + D + +RPAT G SP +R D Sbjct: 123 YGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASFCPVYLRPATAYGVSPFLRFD 182 Query: 176 VSVNLLTMQALAKGKITVFG-GTQVRPNIHIDDITDVYLHLIDHPEITGVYNAGF----- 229 + +N L A+ KG I + GT RP +HI DI+ ++ ++ P V+N F Sbjct: 183 IVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPR-EKVWNEAFNVGST 241 Query: 230 -ENISILDIAKMVAKHIP---VDIVVTESNDPRSYRVNSDKL--LATGFKPSKSVETAIT 283 N I DIA VA ++P ++ D RSYRV+ +KL + KP Sbjct: 242 AHNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTR 301 Query: 284 EIIEKFQSGVLKDED 298 E++ + L E+ Sbjct: 302 ELLAAYSRSTLTVEE 316 >SMb21060 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Sme Sinorhizobium meliloti Length = 349 Score = 142 bits (357), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 100/313 (31%), Positives = 154/313 (49%), Gaps = 16/313 (5%) Query: 1 MNILVTGGCGYKGSVLVPKLLARGYKVHVLD--IMWFGNYLAPHPNLTVTAGDVRNIDQI 58 M +LVTG GY G+VL P L R + V LD I + + DVR+I Sbjct: 1 MKVLVTGHRGYIGAVLTPMLHQRDHDVTGLDSDIFRSCTFEGTLDDTPTMEEDVRDIVID 60 Query: 59 NLDGVDTIIHLSSVANDPCGDLDPKLTWEVSALATMQLADKAVRKGVKQFIYASSGSVYG 118 +L G D +IHL+ ++NDP GD P LT +++ A++ LA A R GV +F++ASS S YG Sbjct: 61 DLAGFDAVIHLAGLSNDPLGDYRPNLTQQINCEASVTLARLAKRAGVPRFLFASSCSNYG 120 Query: 119 VKEELQVTEDLELKPISEYNKTKMVSEPVLLSYKDRMIV-QIVRPATVCGYSPRMRLDVS 177 +TE P++ Y +K+ E + D +R +T G SPR+R D+ Sbjct: 121 AAGSGFLTESAAFNPVTPYGISKVEVEHAVAPMADECFSPTFLRASTAYGLSPRIRFDLV 180 Query: 178 VNLLTMQALAKGKITVFG-GTQVRPNIHIDDITDVYLHLIDHPEITGVYNAGF------E 230 +N LT A G+I + G+ RP +H++DI Y+ ++ + V+N F E Sbjct: 181 LNNLTAWAFTTGQIYLKSDGSPWRPIVHVEDIARAYIAALE-ADRELVHNQAFNVGLTTE 239 Query: 231 NISILDIAKMVAKHIP---VDIVVTESNDPRSYRVNSDKL--LATGFKPSKSVETAITEI 285 N + +IA +V +P ++ D R YRV+ + + FKP + + ++ Sbjct: 240 NYQVREIADIVQAIVPNSRIEFAADAGPDTRCYRVDCNYIGRRLHAFKPQWTARRGVEQL 299 Query: 286 IEKFQSGVLKDED 298 E F S L ED Sbjct: 300 YEAFCSVGLSLED 312 >Cj1427c [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Cje Campylobacter jejuni Length = 313 Score = 142 bits (357), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 105/304 (34%), Positives = 160/304 (52%), Gaps = 22/304 (7%) Query: 3 ILVTGGCGYKGSVLVPKLLARGYKVHVLDIMWFGNY----LAPHPNLTVTAGDV--RNID 56 +L+TGG GY GSVL P LL +GY+V V+D + F + N T GD N+ Sbjct: 5 VLITGGAGYIGSVLTPILLEKGYEVCVIDNLMFDQISLLSCFHNKNFTFINGDAMDENLI 64 Query: 57 QINLDGVDTIIHLSSVANDPCGDLDPKLTWEVSALATMQLADKAVRKGVKQFIYASSGSV 116 + + D II L+++ P +PKL ++ A ++D A + FIY ++ S Sbjct: 65 RQEVAKADIIIPLAALVGAPLCKRNPKLAKMINYEAVKMISDFASPSQI--FIYPNTNSG 122 Query: 117 YGVKE-ELQVTEDLELKPISEYNKTKMVSEPVLLSYKDRMIVQIVRPATVCGYSPRMRLD 175 YG+ E + TE+ L+PISEY K+ +E LL D+ R ATV G SPRMRLD Sbjct: 123 YGIGEKDAMCTEESPLRPISEYGIDKVHAEQYLL---DKGNCVTFRLATVFGISPRMRLD 179 Query: 176 VSVNLLTMQALAKGKITVFGGTQVRPNIHIDDITDVYLHLID-HPEITG-VYNAGFE--N 231 + VN T +A I +F R IH+ D+ ++H I+ + ++ G YN G N Sbjct: 180 LLVNDFTYRAYRDKFIVLFEEHFRRNYIHVRDVVKGFIHGIENYDKMKGQAYNMGLSSAN 239 Query: 232 ISILDIAKMVAKHIPVDIVVTESN-----DPRSYRVNSDKLLATGFKPSKSVETAITEII 286 ++ +A+ + K+IP D + +N D R Y V++ KL ATG+KP ++E I E++ Sbjct: 240 LTKRQLAETIKKYIP-DFYIHSANIGEDPDKRDYLVSNTKLEATGWKPDNTLEDGIKELL 298 Query: 287 EKFQ 290 F+ Sbjct: 299 RAFK 302 >sll0576 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Syn Synechocystis Length = 312 Score = 140 bits (353), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 108/307 (35%), Positives = 160/307 (52%), Gaps = 26/307 (8%) Query: 1 MNILVTGGCGYKGSVLVPKLLARGYKVHVLD-IMWFGNYLAP---HPNLTVTAGDVRNID 56 M IL+TGG GY GSVL P LLA GY+V V+D M+ N LA + V GD R D Sbjct: 3 MKILITGGGGYIGSVLTPTLLAAGYQVTVIDNFMFQQNSLAECCQYETFNVIRGDCRKED 62 Query: 57 QI--NLDGVDTIIHLSSVANDPCGDLDP---KLTWEVSALATMQLADKAVRKGVKQFIYA 111 I L D II L+++ P D K T + + QLA R + Sbjct: 63 LIKEQLKTADVIIPLAALVGAPLCSRDQIGTKTTNQTAVEMICQLASPQQR-----ILMP 117 Query: 112 SSGSVYGVKEELQ-VTEDLELKPISEYNKTKMVSEPVLLSYKDRMIVQIVRPATVCGYSP 170 + S YG+ E+ + TE+ L+PIS Y TK+ +E +L+ + M R ATV G +P Sbjct: 118 VTNSGYGIGEKGKFCTEESPLRPISLYGVTKVEAEKAVLARDNSM---TFRLATVFGMAP 174 Query: 171 RMRLDVSVNLLTMQALAKGKITVFGGTQVRPNIHIDDITDVYLHLIDHPE-ITGV-YNAG 228 RMR+D+ VN +A + +F G R IHI D+ V+LH +++ E + G YN G Sbjct: 175 RMRVDLLVNDFVYRAFYDRAVVIFEGHFKRNYIHIRDVAKVFLHGLENFESMKGKPYNVG 234 Query: 229 FE--NISILDIAKMVAKHIP----VDIVVTESNDPRSYRVNSDKLLATGFKPSKSVETAI 282 E N+S L++ + K++P ++ + E D R Y V++ ++L+TGF P S+ I Sbjct: 235 LEDANLSKLELCAEIRKYLPNFVYLEAPIGEDPDKRDYIVSNQRILSTGFTPDWSLGRGI 294 Query: 283 TEIIEKF 289 E+I+ + Sbjct: 295 QELIKGY 301