BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4200.p (509 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1874 [S] COG2719 Uncharacterized conserved protein Vch Vibrio ... 720 0.0 STM1804 [S] COG2719 Uncharacterized conserved protein Sty Salmon... 714 0.0 YPO2145 [S] COG2719 Uncharacterized conserved protein Ype Yersin... 713 0.0 PA0586 [S] COG2719 Uncharacterized conserved protein Pae Pseudom... 706 0.0 ycgB [S] COG2719 Uncharacterized conserved protein Eco Escherich... 705 0.0 >VC1874 [S] COG2719 Uncharacterized conserved protein Vch Vibrio cholerae Length = 516 Score = 720 bits (1859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/482 (68%), Positives = 407/482 (84%), Gaps = 2/482 (0%) Query: 10 LPCPSDWSFELIERYNEEIARVAKGYALDIYPIQLEIISAEQMMDAYASHGMPVNYRHWS 69 LP DW+FELIERY++EI RVA+ Y LD YP Q+EII++EQMMDAY+S GMP+NY HWS Sbjct: 19 LPDGPDWTFELIERYHQEIRRVAELYRLDTYPNQIEIITSEQMMDAYSSIGMPINYNHWS 78 Query: 70 YGKHFMLTERDYKRGQMGLAYEIVINSDPCIAYLMEENTMTMQALVIAHAAYGHNSFFKG 129 +GK F+ TE+ YK GQMGLAYEIVINSDPCIAYLMEENT+TMQALV+AHA YGHNSFFKG Sbjct: 79 FGKKFIQTEQTYKHGQMGLAYEIVINSDPCIAYLMEENTVTMQALVMAHACYGHNSFFKG 138 Query: 130 NYLFQLWTDASAIIDYLVYARNYIAECEERHGFERVEELLDSCHALMNYGVDRYKRPQRL 189 NYLFQ WTDAS+IIDYL++A+NYIAECE++ G VE+LLDSCHALMNYGVDRYKRP+++ Sbjct: 139 NYLFQTWTDASSIIDYLLFAKNYIAECEQKFGVNEVEKLLDSCHALMNYGVDRYKRPEKI 198 Query: 190 SLAQEKARQREREAYMQSQVNELWRTLPAKKETAAAAVEGRFPSEPQENLLYFAEKNAPL 249 S+A+EKARQ EREAY+QSQVN LWRT+P K+ + RFPSEPQEN+LYF EK+APL Sbjct: 199 SIAEEKARQEEREAYLQSQVNALWRTVP--KKAVEQEKQRRFPSEPQENILYFIEKHAPL 256 Query: 250 LEPWEREVIRIVRKVGQYFYPQRQTQVMNEGWATFWHYTLLNTLYDQGRLTDGFMMEFLH 309 LEPW+RE++RIVRKV QYFYPQ+QTQVMNEGWATFWHYT+LN LYD+G L+D FM+EFLH Sbjct: 257 LEPWQREIVRIVRKVSQYFYPQKQTQVMNEGWATFWHYTILNHLYDEGLLSDKFMLEFLH 316 Query: 310 SHSNVVFQPPITKPYYNGINPYALGFSMMSDIRRICEHPSDEDREWFPDIAGSNWLDTLQ 369 SH++VV QPP Y++GINPYALGF+M DI+RICE P++ED+EWFP++AG+NWLD L Sbjct: 317 SHTSVVAQPPYNSRYFSGINPYALGFAMFRDIKRICEEPTEEDKEWFPELAGANWLDALH 376 Query: 370 HVMRNYKDESFIAQYLSPKLMRDMRMFAVLDDEARSEIEVSAIHNERGFQYVRQALSRQY 429 MRN+KDESFI+QYLSPKL+RD + FA+ DD+ ++ IE+SAIH++ G+Q +R+ L+ QY Sbjct: 377 FAMRNFKDESFISQYLSPKLIRDFKFFAICDDDRKNHIEISAIHDDLGYQQIREKLAAQY 436 Query: 430 DINHREPNIQVWSVNTRGNRSLTLRHFRSDGRSLGDSTNEVLRHMARLWQFDVYLESVDD 489 ++++ EPNIQV+SV+ RG+RSLTL++ D L S EVL+H+ RLW F+V LE V D Sbjct: 437 NLSNLEPNIQVYSVDVRGDRSLTLQYVPHDRIPLDPSYEEVLKHLHRLWGFEVKLEEVKD 496 Query: 490 NG 491 G Sbjct: 497 TG 498 >STM1804 [S] COG2719 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 510 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/485 (67%), Positives = 402/485 (82%) Query: 15 DWSFELIERYNEEIARVAKGYALDIYPIQLEIISAEQMMDAYASHGMPVNYRHWSYGKHF 74 DW+FEL++ Y EI RVAK Y LD YP Q+E+I++EQMMDAY+S GMP+NY HWS+GK F Sbjct: 19 DWTFELLDVYLAEIDRVAKLYQLDTYPHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKF 78 Query: 75 MLTERDYKRGQMGLAYEIVINSDPCIAYLMEENTMTMQALVIAHAAYGHNSFFKGNYLFQ 134 + TER YK GQ GLAYEIVINS+PCIAYLMEENT+TMQALV+AHA YGHNSFFK NYLF+ Sbjct: 79 IETERLYKHGQQGLAYEIVINSNPCIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFR 138 Query: 135 LWTDASAIIDYLVYARNYIAECEERHGFERVEELLDSCHALMNYGVDRYKRPQRLSLAQE 194 WTDAS+I+DYL++ARNYI CEER+G + VE+LLDSCHALMNYGVDRYKRPQ++SL +E Sbjct: 139 SWTDASSIVDYLIFARNYITRCEERYGVDEVEKLLDSCHALMNYGVDRYKRPQKISLQEE 198 Query: 195 KARQREREAYMQSQVNELWRTLPAKKETAAAAVEGRFPSEPQENLLYFAEKNAPLLEPWE 254 KARQ+ RE Y+QSQVN LWRTLP ++E A RFP+EPQENLLYF EKNAPLLEPW+ Sbjct: 199 KARQKSREEYLQSQVNMLWRTLPKREEEKTVAEARRFPAEPQENLLYFMEKNAPLLEPWQ 258 Query: 255 REVIRIVRKVGQYFYPQRQTQVMNEGWATFWHYTLLNTLYDQGRLTDGFMMEFLHSHSNV 314 RE++RIVRKV QYFYPQ+QTQVMNEGWATFWHYT+LN LYD+G++T+ FM+EFLHSH+NV Sbjct: 259 REILRIVRKVSQYFYPQKQTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNV 318 Query: 315 VFQPPITKPYYNGINPYALGFSMMSDIRRICEHPSDEDREWFPDIAGSNWLDTLQHVMRN 374 VFQPP P+Y+GINPYALGF+M DI+RIC+ P+DED+ WFPDIAGS+WL+TL MR+ Sbjct: 319 VFQPPYNSPWYSGINPYALGFAMFQDIKRICQSPTDEDKYWFPDIAGSDWLETLHFAMRD 378 Query: 375 YKDESFIAQYLSPKLMRDMRMFAVLDDEARSEIEVSAIHNERGFQYVRQALSRQYDINHR 434 +KDESFI+Q+LSPK+MRD R F VLDD+ + +E+SAIHNE G++ +R LS QY++++ Sbjct: 379 FKDESFISQFLSPKVMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRSKLSSQYNLSNL 438 Query: 435 EPNIQVWSVNTRGNRSLTLRHFRSDGRSLGDSTNEVLRHMARLWQFDVYLESVDDNGYIV 494 EPNIQVW+V+ RG+RSLTLR+ + L EVL+H+ RLW FDV LE +++G + Sbjct: 439 EPNIQVWNVDLRGDRSLTLRYIPHNRAPLDKGRKEVLKHVHRLWGFDVMLEQQNEDGSVE 498 Query: 495 QRYEC 499 C Sbjct: 499 LLERC 503 >YPO2145 [S] COG2719 Uncharacterized conserved protein Ype Yersinia pestis Length = 511 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/479 (67%), Positives = 400/479 (83%) Query: 15 DWSFELIERYNEEIARVAKGYALDIYPIQLEIISAEQMMDAYASHGMPVNYRHWSYGKHF 74 DW+FEL++ Y ++I RVAK Y LD YP Q+E+I++EQMMDAY+S GMP+NY HWS+GK F Sbjct: 20 DWTFELLQVYLDQIDRVAKHYRLDTYPHQIEVITSEQMMDAYSSIGMPINYTHWSFGKKF 79 Query: 75 MLTERDYKRGQMGLAYEIVINSDPCIAYLMEENTMTMQALVIAHAAYGHNSFFKGNYLFQ 134 + TE+ YK GQ GLAYEIVINS+PCIAYLMEENT+TMQALV+AHA YGHNSFFK NYLF+ Sbjct: 80 IETEQKYKYGQQGLAYEIVINSNPCIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFR 139 Query: 135 LWTDASAIIDYLVYARNYIAECEERHGFERVEELLDSCHALMNYGVDRYKRPQRLSLAQE 194 WTDAS+I+DYL++AR+YI ECEER+G E VE LLDSCHALMNYGVDRYKRPQ++SL +E Sbjct: 140 AWTDASSIVDYLLFARHYINECEERYGVEEVERLLDSCHALMNYGVDRYKRPQKISLVEE 199 Query: 195 KARQREREAYMQSQVNELWRTLPAKKETAAAAVEGRFPSEPQENLLYFAEKNAPLLEPWE 254 ARQ+ RE Y+QSQVN LW+TLP K A R+P+EPQEN+LYF EKNAPLLE W+ Sbjct: 200 TARQKSREEYLQSQVNSLWKTLPRKDREEAPVQAQRYPNEPQENILYFMEKNAPLLESWQ 259 Query: 255 REVIRIVRKVGQYFYPQRQTQVMNEGWATFWHYTLLNTLYDQGRLTDGFMMEFLHSHSNV 314 RE++RIVRKV QYFYPQ+QTQVMNEGWATFWHYT+LN LYD+GR+TD FMMEFLHSH+NV Sbjct: 260 REILRIVRKVSQYFYPQKQTQVMNEGWATFWHYTILNHLYDEGRVTDRFMMEFLHSHTNV 319 Query: 315 VFQPPITKPYYNGINPYALGFSMMSDIRRICEHPSDEDREWFPDIAGSNWLDTLQHVMRN 374 V+QPP PYYNGINPYALGF+M DI++IC+ P++ED WFPDIAG +WLDTL MR+ Sbjct: 320 VYQPPYNSPYYNGINPYALGFAMFQDIKQICQSPTEEDYYWFPDIAGKDWLDTLHFAMRD 379 Query: 375 YKDESFIAQYLSPKLMRDMRMFAVLDDEARSEIEVSAIHNERGFQYVRQALSRQYDINHR 434 +KDESFI+Q+LSPK+MRD R+F VLDD+ + +E+SAIHNE G++ +R LS QY++++ Sbjct: 380 FKDESFISQFLSPKIMRDFRLFTVLDDDKNNYLEISAIHNEEGYRTIRNQLSAQYNLSNH 439 Query: 435 EPNIQVWSVNTRGNRSLTLRHFRSDGRSLGDSTNEVLRHMARLWQFDVYLESVDDNGYI 493 EPNIQVW+V+ RG+RSLTLR+ D L S +V++H+ RLW FDV++E ++D+G I Sbjct: 440 EPNIQVWNVDLRGDRSLTLRYIPHDRAPLDKSRQQVMKHIHRLWGFDVHMEQLNDDGSI 498 >PA0586 [S] COG2719 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 517 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/482 (66%), Positives = 405/482 (84%) Query: 6 KHDPLPCPSDWSFELIERYNEEIARVAKGYALDIYPIQLEIISAEQMMDAYASHGMPVNY 65 K P+ S+W+FELI++Y+ EI+R+A+ YALD YP Q+E+I+AEQMMDAYAS GMP+ Y Sbjct: 3 KRQPIATGSEWTFELIQQYDREISRIAERYALDTYPNQIEVITAEQMMDAYASVGMPIGY 62 Query: 66 RHWSYGKHFMLTERDYKRGQMGLAYEIVINSDPCIAYLMEENTMTMQALVIAHAAYGHNS 125 HWSYGKHF+ TE++YKRGQMGLAYEIVINSDPCIAYLMEENT MQALVIAHA YGHNS Sbjct: 63 NHWSYGKHFLSTEKNYKRGQMGLAYEIVINSDPCIAYLMEENTQCMQALVIAHACYGHNS 122 Query: 126 FFKGNYLFQLWTDASAIIDYLVYARNYIAECEERHGFERVEELLDSCHALMNYGVDRYKR 185 FFKGNYLF+ WTDAS+IIDYLV+A+ YI +CEER+G + VE+LLDSCHALMNYGVDRYKR Sbjct: 123 FFKGNYLFRTWTDASSIIDYLVFAKQYIMQCEERYGIDAVEDLLDSCHALMNYGVDRYKR 182 Query: 186 PQRLSLAQEKARQREREAYMQSQVNELWRTLPAKKETAAAAVEGRFPSEPQENLLYFAEK 245 P +S +E+ RQ+ERE +Q QVN+LWRT+P R+PSEPQEN+LYF EK Sbjct: 183 PYPISAEEERQRQKEREELIQRQVNDLWRTIPRVGGKDKEQSMARYPSEPQENILYFIEK 242 Query: 246 NAPLLEPWEREVIRIVRKVGQYFYPQRQTQVMNEGWATFWHYTLLNTLYDQGRLTDGFMM 305 NAPLLEPW+REVIRIVRK+ QYFYPQRQTQVMNEGWATFWHYTLLN LYD+G + DGFMM Sbjct: 243 NAPLLEPWQREVIRIVRKIAQYFYPQRQTQVMNEGWATFWHYTLLNDLYDEGLVNDGFMM 302 Query: 306 EFLHSHSNVVFQPPITKPYYNGINPYALGFSMMSDIRRICEHPSDEDREWFPDIAGSNWL 365 EFL H++VV+QP PYY+GINPYALGF+M DIRRICE P+DEDR WFPDIAGS+WL Sbjct: 303 EFLQYHTSVVYQPSFDSPYYSGINPYALGFAMYRDIRRICEEPTDEDRRWFPDIAGSDWL 362 Query: 366 DTLQHVMRNYKDESFIAQYLSPKLMRDMRMFAVLDDEARSEIEVSAIHNERGFQYVRQAL 425 TL+ M+++KDESFI Q+LSPK++RD+++F++LDD+ + ++ V+AIH+E G++ +R+ L Sbjct: 363 ATLKFAMKSFKDESFILQFLSPKVIRDLKLFSILDDDQKDDLLVAAIHDEAGYRTIRETL 422 Query: 426 SRQYDINHREPNIQVWSVNTRGNRSLTLRHFRSDGRSLGDSTNEVLRHMARLWQFDVYLE 485 + QY++ +REPNIQ+W+V+ RG+RSLTLRH + D + L DST +VL+H+ RLW FD++LE Sbjct: 423 AAQYNLGNREPNIQIWNVDRRGDRSLTLRHQQFDRQPLSDSTADVLKHLHRLWGFDIHLE 482 Query: 486 SV 487 ++ Sbjct: 483 TL 484 >ycgB [S] COG2719 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 510 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/479 (67%), Positives = 399/479 (83%) Query: 15 DWSFELIERYNEEIARVAKGYALDIYPIQLEIISAEQMMDAYASHGMPVNYRHWSYGKHF 74 DW+F+L++ Y EI RVAK Y LD YP Q+E+I++EQMMDAY+S GMP+NY HWS+GK F Sbjct: 19 DWTFDLLDVYLAEIDRVAKLYRLDTYPHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKF 78 Query: 75 MLTERDYKRGQMGLAYEIVINSDPCIAYLMEENTMTMQALVIAHAAYGHNSFFKGNYLFQ 134 + TER YK GQ GLAYEIVINS+PCIAYLMEENT+TMQALV+AHA YGHNSFFK NYLF+ Sbjct: 79 IETERLYKHGQQGLAYEIVINSNPCIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFR 138 Query: 135 LWTDASAIIDYLVYARNYIAECEERHGFERVEELLDSCHALMNYGVDRYKRPQRLSLAQE 194 WTDAS+I+DYL++AR YI ECEER+G + VE LLDSCHALMNYGVDRYKRPQ++SL +E Sbjct: 139 SWTDASSIVDYLIFARKYITECEERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEE 198 Query: 195 KARQREREAYMQSQVNELWRTLPAKKETAAAAVEGRFPSEPQENLLYFAEKNAPLLEPWE 254 KARQ+ RE Y+QSQVN LWRTLP ++E A R+PSEPQENLLYF EKNAPLLE W+ Sbjct: 199 KARQKSREEYLQSQVNMLWRTLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQ 258 Query: 255 REVIRIVRKVGQYFYPQRQTQVMNEGWATFWHYTLLNTLYDQGRLTDGFMMEFLHSHSNV 314 RE++RIVRKV QYFYPQ+QTQVMNEGWATFWHYT+LN LYD+G++T+ FM+EFLHSH+NV Sbjct: 259 REILRIVRKVSQYFYPQKQTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNV 318 Query: 315 VFQPPITKPYYNGINPYALGFSMMSDIRRICEHPSDEDREWFPDIAGSNWLDTLQHVMRN 374 VFQPP P+Y+GINPYALGF+M DI+RIC+ P++ED+ WFPDIAGS+WL+TL MR+ Sbjct: 319 VFQPPYNSPWYSGINPYALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRD 378 Query: 375 YKDESFIAQYLSPKLMRDMRMFAVLDDEARSEIEVSAIHNERGFQYVRQALSRQYDINHR 434 +KDESFI+Q+LSPK+MRD R F VLDD+ + +E+SAIHNE G++ +R LS QY++++ Sbjct: 379 FKDESFISQFLSPKVMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNL 438 Query: 435 EPNIQVWSVNTRGNRSLTLRHFRSDGRSLGDSTNEVLRHMARLWQFDVYLESVDDNGYI 493 EPNIQ+W+V+ RG+RSLTLR+ + L EVL+H+ RLW FDV LE +++G I Sbjct: 439 EPNIQIWNVDLRGDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSI 497