BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4180.p (1055 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0800 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralsto... 1188 0.0 PA0669 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudom... 1035 0.0 SMa0892 [L] COG0587 DNA polymerase III, alpha subunit Sme Sinorh... 873 0.0 CC3211 [L] COG0587 DNA polymerase III, alpha subunit Ccr Cauloba... 863 0.0 BMEI1876 [L] COG0587 DNA polymerase III, alpha subunit Bme Bruce... 862 0.0 >RSp0800 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralstonia solanacearum Length = 1075 Score = 1188 bits (3074), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/1074 (58%), Positives = 772/1074 (71%), Gaps = 30/1074 (2%) Query: 5 LPLGGPAASAIPDYAELFCLSNFSFLEGASHAEELAARAVQLGYTALAVTDECSLAGVVR 64 LP+G +PDYAEL C+SNF+FL GASH EL ARA GY ALA+TDECS+AG VR Sbjct: 7 LPIG------LPDYAELHCISNFTFLTGASHPHELVARAQAFGYRALALTDECSVAGTVR 60 Query: 65 AHVETRDAGIKLIIGSFFRIEWEAGKPPLTLIALAQNREGYGNLSELITLGRTRVEKGSY 124 AH+ ++AG+KLIIGS F + G+P L L+ LAQ+ +GYGNL E IT R KG Y Sbjct: 61 AHMAAKEAGLKLIIGSRFTVRDAQGEPWLRLVLLAQDIDGYGNLCECITQARLAAPKGDY 120 Query: 125 HLSLDDLAAPLAAHRHLRGLPDCLLILAPHYPADAATLERQARWLQETFPQRAWLGLTQL 184 L DDLAAP HLRG+P CL IL P Y D L QA+W ++ F R + L Sbjct: 121 RLLADDLAAPAGELAHLRGMPHCLAILLPDYDPDPRHLLAQAQWCRQVFGDRLSMALELP 180 Query: 185 YRPFDALHRSVIDTVARRHGLPVTALGQVNMHVRSRKPLQDTLTAIRLGKAVSECGYDLA 244 R D HR + V+ + +P+ A G V MH R RKPL D LTAIRL + ++ECG LA Sbjct: 181 LRHADDRHRGTVAAVSEQTDVPMVATGDVAMHSRQRKPLHDVLTAIRLSRPIAECGLALA 240 Query: 245 PNAEQHLRSRLRLANVFP----ASALQESLRIASLCHFKLSELRYEYPEELVPDGQTPAG 300 P+AEQ +R+R++LA + A L+ S+ +ASLC F L E+ YEYP E+VP+GQTPAG Sbjct: 241 PSAEQAMRTRMQLAFFYQGERGAQVLRRSVELASLCDFSLDEIAYEYPHEVVPEGQTPAG 300 Query: 301 YLRQEVYLGAHLRYPAGIPQKVIDQIEHELTLINDMAYEAYFLTVYDIVRFAKDQGILRQ 360 YL EV GA RY IP KV Q++ EL LI ++ YE +FLTVYD+VRFA+ Q IL Q Sbjct: 301 YLLAEVMAGAARRYGKDIPSKVRAQLDEELALIAELRYEPFFLTVYDVVRFARSQSILCQ 360 Query: 361 GRGSAANSVVCYCLGVTEVDPTCSVMLFERFISKERGEPPDIDVDFEHQRREEVIQYIYR 420 GRGSAANS VCYCLG+TEV+P LF RF+S+ R EPPDIDVDFEHQRREEVIQYIY+ Sbjct: 361 GRGSAANSAVCYCLGITEVNPESGNTLFARFLSRARNEPPDIDVDFEHQRREEVIQYIYK 420 Query: 421 KYGRMRAAIAAAVHTYRPRGVLRDVGKALGVDASIVDKVAKSQQWFDSRDNMLERFAECG 480 KYG R A+AAA+ TYR R LRDVG+ALG+D ++++VAK+Q W+D R +R + G Sbjct: 421 KYGVTRTALAAALITYRTRSALRDVGRALGIDLGVIEQVAKAQAWWDGRHEFAQRAGQQG 480 Query: 481 LDASSPIAQQWAMLALQLIKFPRHLSQHTGGFVIARHKLSRLVPIENAAMPERSVIQWDK 540 LD SP+ Q+WA L QL FPRHLSQH GGFVIA+ KLSRLVPIENAAMPER VIQWDK Sbjct: 481 LDPESPLVQRWAGLIEQLRGFPRHLSQHVGGFVIAQGKLSRLVPIENAAMPERRVIQWDK 540 Query: 541 DDLESLGLLKVDILALGMLSALRRALELV----GQR--RGAP--FTMQDIPREDPATYDM 592 DDLESL LLKVD+LALGML+A+RR L+++ G+R GAP MQ +P ED ATY+M Sbjct: 541 DDLESLRLLKVDVLALGMLTAIRRTLDMLDALPGRRAHYGAPDKLAMQHLPDEDTATYEM 600 Query: 593 ICQADTVGVFQIESRAQMSMLPRLQPRRFYDLVVQVAIVRPGPIQGGMVHPFLRRR---- 648 IC+A+T+GVFQIESRAQ SMLPRL+PR +YDLV+QVAIVRPGPIQGGMVHP+L+RR Sbjct: 601 ICRAETIGVFQIESRAQQSMLPRLRPRTYYDLVIQVAIVRPGPIQGGMVHPYLQRREAVR 660 Query: 649 -AGEEAETYPKEILRQALERTRGVPIFQEQVMQIAVLAAGFTPGEADGLRRAMAAWKRKG 707 + TYP ++ LERT GVPIFQEQVM+IA+ A GFT EAD LRR MAAWKRKG Sbjct: 661 NGNPDCVTYPGPEVKAVLERTLGVPIFQEQVMEIAMKAGGFTADEADRLRRDMAAWKRKG 720 Query: 708 GMDKYQIKLIDGML-ARGYDKSFAEAIFRQIQGFGEYGFPESHAASFALLAYASSWIKCH 766 + ++Q +L+ M+ R YD +F EA+ RQ++GF EYGFPESHAA FA LAY SS++KCH Sbjct: 721 NLTQHQARLMKEMVEVRHYDPAFVEALCRQMEGFAEYGFPESHAAGFARLAYVSSFLKCH 780 Query: 767 EPEAFLCSLLNSQPMGFYSPSQLIQDARRHGVQVLPADVMCSHWESTLE---EIQAPRPA 823 EP AF +LLNSQPMGFYSPSQL+Q+ARR V+VLPADV S W+STL + +P Sbjct: 781 EPAAFFAALLNSQPMGFYSPSQLVQEARRSRVRVLPADVTASAWDSTLHARPDGAGGQPD 840 Query: 824 VRLGLSLLGSMREEAAQRIAQARRSAPFTDLPDLALRAHLDKRDLQALAAGNALHALSGN 883 +RLGL+ + MR A +RI AR APF+ + DLA RA LD+ DL LAA NAL +L+G+ Sbjct: 841 IRLGLNRIRGMRPAAGERIVVARAQAPFSSVEDLAHRAALDRHDLSVLAAANALLSLAGH 900 Query: 884 RREALWQALD-AAPTSD--LLRSAPSREATLRLPPPSEAQDIVADYRSAGLTLRRHPLAL 940 RR+ALWQ L P D LLR A EA L LP PS +++VADY S GL+L+ HPL+L Sbjct: 901 RRQALWQTLALQEPGQDHALLRQARPVEAPLVLPAPSLGEEVVADYGSLGLSLQSHPLSL 960 Query: 941 LRPLLRKQKFLSHEVMASFQDGQFARGCGIVTVRQRPGTAKGVLFLTIEDETGSTNVIVW 1000 LRP L + +F++ +A +++GQ AR CGIVTVRQRPGTAKG +F++IEDETG+ NV++W Sbjct: 961 LRPRLERMRFVTAAALAGYRNGQLARACGIVTVRQRPGTAKGTIFVSIEDETGAVNVVLW 1020 Query: 1001 PALVAKQRNEVLNASLLGVYGIWQSHAGVKHLVAKRLVDLSHLLGDISVNSRDF 1054 P L+ +QR EVL+A LLGVYG WQ +HLVA+ LVDL+ LLG ++ +SRDF Sbjct: 1021 PRLIERQRREVLHARLLGVYGKWQCERETRHLVAQHLVDLTPLLGRLASSSRDF 1074 >PA0669 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudomonas aeruginosa Length = 1031 Score = 1035 bits (2676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 553/1040 (53%), Positives = 698/1040 (67%), Gaps = 23/1040 (2%) Query: 18 YAELFCLSNFSFLEGASHAEELAARAVQLGYTALAVTDECSLAGVVRAHVETRDAGIKLI 77 YAEL CLSNFSF GAS A EL ARA +LGY ALA+TDECSLAG+VRA R+ ++LI Sbjct: 11 YAELHCLSNFSFQRGASSATELFARAARLGYRALAITDECSLAGIVRAWQAAREHQVQLI 70 Query: 78 IGSFFRIEWEAGKPPLTLIALAQNREGYGNLSELITLGRTRVEKGSYHLSLDDLAAPLAA 137 +GS R+E + P L+ LA++ EGY NL LIT GR + +KG Y L +DL PLA Sbjct: 71 VGSEIRLE----QGP-KLVLLAEDLEGYQNLCRLITRGRRQADKGHYRLLREDLQQPLAG 125 Query: 138 HRHLRGLPDCLLILAPHYPADAATLERQARWLQETFPQRAWLGLTQLYRPFDALHR-SVI 196 +LA P D + QA WL+E FPQR WLG+ +L+R D R + Sbjct: 126 ------------LLAIWLPNDHG--DEQAAWLRERFPQRLWLGV-ELHRGADDDARLDKL 170 Query: 197 DTVARRHGLPVTALGQVNMHVRSRKPLQDTLTAIRLGKAVSECGYDLAPNAEQHLRSRLR 256 +A LP A G V+MH R R+ LQD +TAIR VSE G L PN E+HLR+ Sbjct: 171 LALASHLRLPPVACGDVHMHARGRRALQDCMTAIRNHLPVSEAGAYLFPNGERHLRTLEA 230 Query: 257 LANVFPASALQESLRIASLCHFKLSELRYEYPEELVPDGQTPAGYLRQEVYLGAHLRYPA 316 L ++P + L E+L+IA C F L +L+Y+YP ELVP G PA +LR G R+P Sbjct: 231 LQGIYPQALLAETLKIAERCRFDLEQLKYQYPRELVPAGHDPASWLRHLTEQGIARRWPN 290 Query: 317 GIPQKVIDQIEHELTLINDMAYEAYFLTVYDIVRFAKDQGILRQGRGSAANSVVCYCLGV 376 G KV QIE EL LI ++ YE+YFLTV DIV FA+ + IL QGRGSAANS VC+ LG+ Sbjct: 291 GASAKVRKQIERELELIAELGYESYFLTVQDIVAFARGRKILCQGRGSAANSAVCFALGI 350 Query: 377 TEVDPTCSVMLFERFISKERGEPPDIDVDFEHQRREEVIQYIYRKYGRMRAAIAAAVHTY 436 TE+DP + +LFERF+S+ER EPPDIDVDFEH+RREEVIQY++ +YGR RAA+ A V TY Sbjct: 351 TELDPDRTNLLFERFLSRERNEPPDIDVDFEHERREEVIQYVFTRYGRQRAALTAVVSTY 410 Query: 437 RPRGVLRDVGKALGVDASIVDKVAKSQQWFDSRDNMLERFAECGLDASSPIAQQWAMLAL 496 G +RDV KALG+ VD +A + + ER E G D SPI ++ L Sbjct: 411 HGAGAVRDVAKALGLPPEQVDVLANCCGRWSDQAPSAERLEEAGFDPQSPILRRVLALTD 470 Query: 497 QLIKFPRHLSQHTGGFVIARHKLSRLVPIENAAMPERSVIQWDKDDLESLGLLKVDILAL 556 +LI FPRHLSQH GGFVI+ L LVP+ENA+M ER+VIQWDKDDL+++GLLKVD+LAL Sbjct: 471 ELIGFPRHLSQHPGGFVISEQPLDTLVPVENASMAERTVIQWDKDDLDAVGLLKVDVLAL 530 Query: 557 GMLSALRRALELVGQRRGAP-FTMQDIPREDPATYDMICQADTVGVFQIESRAQMSMLPR 615 GMLSALRR+ +L+ RG ++ IP EDPATY+MI +ADT+GVFQIESRAQM+MLPR Sbjct: 531 GMLSALRRSFDLIHALRGGKRLSIASIPSEDPATYEMISRADTIGVFQIESRAQMAMLPR 590 Query: 616 LQPRRFYDLVVQVAIVRPGPIQGGMVHPFLRRRAGEEAETYPKEILRQALERTRGVPIFQ 675 L+P++FYDLV+QVAIVRPGPIQG MVHP+LRRR GEE YP L + ERT GVP+FQ Sbjct: 591 LRPQKFYDLVIQVAIVRPGPIQGDMVHPYLRRRNGEEPVAYPSAELEEVFERTLGVPLFQ 650 Query: 676 EQVMQIAVLAAGFTPGEADGLRRAMAAWKRKGGMDKYQIKLIDGMLARGYDKSFAEAIFR 735 EQVM++A++AA +TPGEAD LRR+MAAWKR GG++ ++ +L GMLA+GY+ FA IF Sbjct: 651 EQVMELAIVAADYTPGEADELRRSMAAWKRHGGLEHHRERLTRGMLAKGYEADFAARIFE 710 Query: 736 QIQGFGEYGFPESHAASFALLAYASSWIKCHEPEAFLCSLLNSQPMGFYSPSQLIQDARR 795 QI+GFG YGFPESHAASFALL YASSW+K HEP AF C+L+NS PMGFYSP QL+QDARR Sbjct: 711 QIKGFGSYGFPESHAASFALLTYASSWLKRHEPAAFACALINSWPMGFYSPDQLLQDARR 770 Query: 796 HGVQVLPADVMCSHWESTLEEIQAPRPAVRLGLSLLGSMREEAAQRIAQARRSAPFTDLP 855 H +Q P DV S W+ +LE +PA+RLGL ++ REE A+RI Q R + PF D+ Sbjct: 771 HALQTRPVDVRHSGWDCSLESFGQAQPAIRLGLRMIRGFREEDARRIEQVREAEPFLDVH 830 Query: 856 DLALRAHLDKRDLQALAAGNALHALSGNRREALWQALDAAPTSDLLRSAPS-REATLRLP 914 DL RA LD R L+ LA AL L+G+R +A W P L + E+T+ LP Sbjct: 831 DLGRRARLDARALELLADAGALRGLAGHRHKARWAVASVEPQLPLFAEGTAIEESTVSLP 890 Query: 915 PPSEAQDIVADYRSAGLTLRRHPLALLRPLLRKQKFLSHEVMASFQDGQFARGCGIVTVR 974 PS +++++DY G TL HPL LLR L+ ++ +A G+ R G+V R Sbjct: 891 LPSRGEELLSDYALLGTTLGPHPLKLLRGQLKARRCRDSRELAKLGHGRPIRVAGLVVGR 950 Query: 975 QRPGTAKGVLFLTIEDETGSTNVIVWPALVAKQRNEVLNASLLGVYGIWQSHAGVKHLVA 1034 QRP TA G+ F+T+EDE G NV+V L +QR L + LL V GI +S V+H++A Sbjct: 951 QRPQTASGITFITLEDEFGMVNVVVRHDLAERQRRPFLESRLLQVEGILESSGEVRHVIA 1010 Query: 1035 KRLVDLSHLLGDISVNSRDF 1054 RL DL+ LL + V SRDF Sbjct: 1011 GRLHDLTPLLTGLDVRSRDF 1030 >SMa0892 [L] COG0587 DNA polymerase III, alpha subunit Sme Sinorhizobium meliloti Length = 1087 Score = 873 bits (2255), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/1046 (45%), Positives = 650/1046 (62%), Gaps = 33/1046 (3%) Query: 18 YAELFCLSNFSFLEGASHAEELAARAVQLGYTALAVTDECSLAGVVRAHVETRDAGIKLI 77 YAEL ++FSFL AS AEEL A A +G AL V D SLAG+VRA +R G++L+ Sbjct: 3 YAELQVTTHFSFLRAASSAEELFATARLMGIEALGVVDRNSLAGIVRALEASRATGLRLV 62 Query: 78 IGSFFRIEWEAGKPPLTLIALAQNREGYGNLSELITLGRTRVEKGSYHLSLDDLAAPLAA 137 +G R++ + G ++++ +R Y L+ L+TLG+ R K + + DD+A Sbjct: 63 VGC--RLDLQDG---MSILVYPTDRAAYSRLTRLLTLGKGRGGKANCIIHFDDVAL---- 113 Query: 138 HRHLRGLPDCLLILAPHYPADAATLERQARWLQETFPQRAWLGLTQLYRPFDALHRSVID 197 + GL + IL P + + Q R + E F RA++ L RP D L + Sbjct: 114 --YAEGL---IGILVPDLADEVCAV--QLRKIAEVFGDRAYVSLCLRRRPNDQLQLHELT 166 Query: 198 TVARRHGLPVTALGQVNMHVRSRKPLQDTLTAIRLGKAVSECGYDLAPNAEQHLRSRLRL 257 +A +H + V H R+ LQD +T IR G + + G++ +A+++L+ + Sbjct: 167 NLAVKHRVKTIVTNDVLFHEHGRRQLQDVVTCIRTGMTIDDVGFERERHADRYLKPPEEM 226 Query: 258 ANVFPA--SALQESLRIASLCHFKLSELRYEYPEELVPDGQTPAGYLRQEVYLGAHLRYP 315 A +FPA AL ++ I C F L EL Y+YPEE + G T L+ + G RYP Sbjct: 227 ARLFPAYPEALARTMEIVERCRFSLEELVYQYPEEALILGMTAQQSLQHYTWEGVRARYP 286 Query: 316 AGIPQKVIDQIEHELTLINDMAYEAYFLTVYDIVRFAKDQGILRQGRGSAANSVVCYCLG 375 G+P V I HEL LI M Y YFLTV+ IVR+A+ QGIL QGRGSAANS VCY LG Sbjct: 287 EGLPTHVEKTIRHELALIETMKYAPYFLTVFSIVRYARSQGILCQGRGSAANSAVCYVLG 346 Query: 376 VTEVDPTCSVMLFERFISKERGEPPDIDVDFEHQRREEVIQYIYRKYGRMRAAIAAAVHT 435 +T +DP + +LFERF+S+ER EPPDIDVDFEH+RREEVIQ+IY+ YG +AA+ + V Sbjct: 347 ITSIDPETNDLLFERFVSQERDEPPDIDVDFEHERREEVIQWIYKTYGHDKAALCSTVTR 406 Query: 436 YRPRGVLRDVGKALGVDASIVDKVAKSQQWFDSRDNMLERFAECGLDASSPIAQQWAMLA 495 YR +G +RDVGKAL + ++ + S W S + E GL+ LA Sbjct: 407 YRAKGAIRDVGKALDLPEDLI-RTLSSGIWSWSETVGERQVRELGLNPDDRRLTLTLRLA 465 Query: 496 LQLIKFPRHLSQHTGGFVIARHKLSRLVPIENAAMPERSVIQWDKDDLESLGLLKVDILA 555 QL+ PR+LSQH GGFV+ +L LVPIE A M +R VI+WDKDD+E+L LKVD+LA Sbjct: 466 QQLMGAPRNLSQHPGGFVLTHDRLDDLVPIEPATMADRQVIEWDKDDIEALKFLKVDVLA 525 Query: 556 LGMLSALRRALELVGQRRGAPFTMQDIPREDPATYDMICQADTVGVFQIESRAQMSMLPR 615 LGML+ + +A L+ + + + IP+EDPATY MI +ADT+G FQIESRAQMSMLPR Sbjct: 526 LGMLTCMAKAFALISEHKHEDIDLATIPQEDPATYAMIRKADTLGTFQIESRAQMSMLPR 585 Query: 616 LQPRRFYDLVVQVAIVRPGPIQGGMVHPFLRRRAGEEAETYPKEILRQALERTRGVPIFQ 675 ++PR FYDLV+QVAIVRPGPIQG MVHP+LRRR G+E YP L L +T GVP+FQ Sbjct: 586 MKPRTFYDLVIQVAIVRPGPIQGDMVHPYLRRREGKEKVEYPTPELEAVLHKTLGVPLFQ 645 Query: 676 EQVMQIAVLAAGFTPGEADGLRRAMAAWKRKGGMDKYQIKLIDGMLARGYDKSFAEAIFR 735 E M++A++ AGFT GEAD LR++MA +K GG+ +++ KL++GM+ GY K FAE F Sbjct: 646 ESAMRVAMVCAGFTGGEADQLRKSMATFKFTGGVSRFKDKLVNGMIRNGYTKEFAEKTFS 705 Query: 736 QIQGFGEYGFPESHAASFALLAYASSWIKCHEPEAFLCSLLNSQPMGFYSPSQLIQDARR 795 Q++GFG YGFPESHAASFAL+AYAS++IKC+ P+ F +LLNSQPMGFY+P+Q+++DAR Sbjct: 706 QLEGFGSYGFPESHAASFALIAYASNYIKCYFPDVFCAALLNSQPMGFYAPAQIVRDARE 765 Query: 796 HGVQVLPADVMCSHWESTLEEIQAPRP-AVRLGLSLLGSMREEAAQRIAQARRSAPFTDL 854 HGV+V P + S W+ LE I AVRLG+ L+ + A RI AR PFT + Sbjct: 766 HGVEVRPICINRSRWDCMLEPIDGSGGHAVRLGMRLVRGLATADAARIVAARADEPFTSV 825 Query: 855 PDLALRAHLDKRDLQALAAGNA-LHALSGNRREALW--QALDAAPTSDLLRSAPSREA-- 909 D+ R+ + L LA +A L +LS RR+ALW +AL P L +A REA Sbjct: 826 DDMWRRSGVPVASLVELAEADAFLPSLSLERRDALWAIKALRDEPLP-LFTAAADREARA 884 Query: 910 -------TLRLPPPSEAQDIVADYRSAGLTLRRHPLALLRPLLRKQKFLSHEVMASFQDG 962 + L ++ Q++V DY GLTLR HPL +R L K++ ++ + DG Sbjct: 885 IAEQEEPEVELRQMTDGQNVVEDYSHTGLTLREHPLRFMRDDLAKRRIVTCAQAMTAHDG 944 Query: 963 QFARGCGIVTVRQRPGTAKGVLFLTIEDETGSTNVIVWPALVAKQRNEVLNASLLGVYGI 1022 Q+ G+V VRQRPG+AKGV+F+TIEDETG N++VWP L + R VL AS++ + G Sbjct: 945 QWLMAAGLVLVRQRPGSAKGVMFITIEDETGIANIVVWPKLFERSRRVVLGASMMAINGR 1004 Query: 1023 WQSHAGVKHLVAKRLVDLSHLLGDIS 1048 Q V HLVA++L DLS L ++ Sbjct: 1005 IQREGEVVHLVAQQLFDLSADLSSLA 1030 >CC3211 [L] COG0587 DNA polymerase III, alpha subunit Ccr Caulobacter vibrioides Length = 1083 Score = 863 bits (2231), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/1076 (44%), Positives = 653/1076 (60%), Gaps = 66/1076 (6%) Query: 16 PDYAELFCLSNFSFLEGASHAEELAARAVQLGYTALAVTDECSLAGVVRAHVETRDAGIK 75 P YAEL +NFSFL GASHAEELA A LG TA+ + D SLAGVVRA + I+ Sbjct: 4 PVYAELQATTNFSFLRGASHAEELALTAEALGLTAIGIVDRNSLAGVVRAWTAAKRRSIR 63 Query: 76 LIIGSFFRIEWEAGKPPLTLIALAQNREGYGNLSELITLGRTRVEKGSYHLSLDDLAAPL 135 ++ G R+++ G P +L+ +RE +G L+ L+T+G+ R EKG HL+ D Sbjct: 64 VLTGC--RLDFMDGAP--SLLCYPTDREAFGRLTRLLTIGQLRAEKGECHLTWRDFLD-- 117 Query: 136 AAHRHLRGLPDCLLILAPHYPADAATLERQARWLQETFPQRAWLGLTQLYRPFDALHRSV 195 H G LI+ P D + E+ + R+WL ++ Y D + Sbjct: 118 ----HSEG--QLGLIVPPRVLDD--SFEQHLTRMAGDLRGRSWLAASRAYAARDLQRLAR 169 Query: 196 IDTVARRHGLPVTALGQVNMHVRSRKPLQDTLTAIRLGKAVSECGYDLAPNAEQHLRSRL 255 ++++ R G P+ A V H R+PLQD ++ +R A+ E G+ L NAE+H++S Sbjct: 170 LESLGRTSGAPIVATNDVLYHGPERRPLQDVISCVREHCAIQEAGFRLEANAERHIKSPE 229 Query: 256 RLANVFP--ASALQESLRIASLCHFKLSELRYEYPEELVPDGQTPAGYLRQEVYLGAHLR 313 +A +F A++ ++ I F L ++R +YP+E VP G+T +L + GA R Sbjct: 230 EMARLFDRWPRAVERTVEIVERIGFDLKDIREQYPDEPVPPGKTAMQHLTDLTWKGAAWR 289 Query: 314 YPAGIPQKVIDQIEHELTLINDMAYEAYFLTVYDIVRFAKDQGILRQGRGSAANSVVCYC 373 YP G+ KV QI+ EL LI M Y YF+TV+DIVR A+ GIL QGRGSAANS VC+C Sbjct: 290 YPNGVSPKVTAQIQEELRLIEKMDYPNYFITVHDIVREARSMGILCQGRGSAANSSVCFC 349 Query: 374 LGVTEVDPTCSVMLFERFISKERGEPPDIDVDFEHQRREEVIQYIYRKYGRMRAAIAAAV 433 LGVT +DPT +LF RFIS+ RGEPPDIDVDFEH RREEV+QY++++YGR AAI V Sbjct: 350 LGVTAIDPTEHRLLFTRFISENRGEPPDIDVDFEHDRREEVMQYVFQRYGRAYAAICGTV 409 Query: 434 HTYRPRGVLRDVGKALGVDASIVDKVAKSQQWFDSRDNMLE-RFAECGLDASSPIAQQWA 492 YRPR +RDVGKALG+ + +A + W D + E GLD +P + Sbjct: 410 IHYRPRSAIRDVGKALGLTEDVTSLLAGT-VWGSWGDGLPEDHLRNAGLDPKAPEIARAV 468 Query: 493 MLALQLIKFPRHLSQHTGGFVIARHKLSRLVPIENAAMPERSVIQWDKDDLESLGLLKVD 552 LA LI FPRHLSQH GGFV+ + +L VPI AAM +R+ I+WDKDD++SLGL+KVD Sbjct: 469 GLANDLIGFPRHLSQHVGGFVLTKRRLDETVPIGKAAMKDRTFIEWDKDDIDSLGLMKVD 528 Query: 553 ILALGMLSALRRALELVGQRRGAPF--TMQDIPREDPATYDMICQADTVGVFQIESRAQM 610 ILALGML A++RA+ ++ + G + + DIP+E P YDM+C AD+VGVFQ+ESRAQM Sbjct: 529 ILALGMLHAIQRAMTMLREDHGQDWLKDLADIPKEVPGVYDMLCAADSVGVFQVESRAQM 588 Query: 611 SMLPRLQPRRFYDLVVQVAIVRPGPIQGGMVHPFLRRRAGEEAETYPK--------EILR 662 SMLPRL+PR FYDLV+QVAIVRPGPIQG MVHP+L+RR EE +PK + L+ Sbjct: 589 SMLPRLRPREFYDLVIQVAIVRPGPIQGDMVHPYLKRRNKEEPVDWPKPSPEHGPPDELQ 648 Query: 663 QALERTRGVPIFQEQVMQIAVLAAGFTPGEADGLRRAMAAWKRKGGMDKYQIKLIDGMLA 722 + L +T GVP+FQEQ M +A+ AA FTP EADGLR+AMA ++ G D Y+ K I+GM+ Sbjct: 649 EILGKTFGVPLFQEQAMSLAIEAAKFTPDEADGLRKAMATFRNLGSPDAYRNKFIEGMVG 708 Query: 723 RGYDKSFAEAIFRQIQGFGEYGFPESHAASFALLAYASSWIKCHEPEAFLCSLLNSQPMG 782 RGY+++FAE F+QI+GF YGFPESHAASFA L Y S+WIK P+ F +L+N+QPMG Sbjct: 709 RGYERAFAERCFKQIEGFSHYGFPESHAASFAKLVYVSAWIKWAWPDVFCAALINAQPMG 768 Query: 783 FYSPSQLIQDARRHGVQVLPADVMCSHWESTLEEI----------------QAPRP---A 823 FY P+QL++DAR HGV+VLP D++ S W+ TL I Q RP A Sbjct: 769 FYQPAQLVRDAREHGVEVLPPDILTSDWDCTLAPISTGFRPPRVRHDKVACQETRPRWKA 828 Query: 824 VRLGLSLLGSMREE------AAQRIAQARRSAPFTDLPDLALRAHLDKRDLQALAAGNAL 877 VRLG + +RE R AR A F + + ++ L+ LA +A Sbjct: 829 VRLGFRQIKGLRETLDIPPLLKARGEGARTPAEFA-------QGGVPQKALELLAEADAF 881 Query: 878 HALSGNRREALW-----QALDAAPT-SDLLRSAPSREATLRLPPPSEAQDIVADYRSAGL 931 ++ +RREALW + AP + LL P E + LP + Q++ DYR+ L Sbjct: 882 ASVGLSRREALWAVKGLKGEHKAPVQAPLLAGLPLFEERVALPAMAATQEVAEDYRTTSL 941 Query: 932 TLRRHPLALLRPLLRKQKFLSHEVMASFQDGQFARGCGIVTVRQRPGTAKGVLFLTIEDE 991 +L+ HP+ R +L + + E + S +DG G+V +RQRPGTAKGV+F+T+EDE Sbjct: 942 SLKAHPIGFYRSMLAARGVVPAERLLSLKDGARVSVAGLVLIRQRPGTAKGVVFVTLEDE 1001 Query: 992 TGSTNVIVWPALVAKQRNEVLNASLLGVYGIWQSHAGVKHLVAKRLVDLSHLLGDI 1047 TG N +VW RN V+ AS L V+G Q V H+VA+R DLS L + Sbjct: 1002 TGVANAVVWKDRFDAARNVVMTASFLIVHGRVQRADNVIHVVAERFTDLSAELSSL 1057 >BMEI1876 [L] COG0587 DNA polymerase III, alpha subunit Bme Brucella melitensis Length = 1078 Score = 862 bits (2227), Expect = 0.0, Method: Compositional matrix adjust. Identities = 483/1061 (45%), Positives = 656/1061 (61%), Gaps = 47/1061 (4%) Query: 18 YAELFCLSNFSFLEGASHAEELAARAVQLGYTALAVTDECSLAGVVRAHVETRD----AG 73 Y E+ SNFSFL GASH +EL RA L + + + D +LAGVVRAH + +D +G Sbjct: 5 YFEMAAASNFSFLCGASHPQELVERAHALDLSGIGIADRNTLAGVVRAHAQWKDIRKESG 64 Query: 74 IKLIIGSFFRIEWEAGKPPLTLIALAQNREGYGNLSELITLGRTRVE-KGSYHLSLDDLA 132 +L IG R+ + G P ++ ++R YG L L+T G+ R KG HL DL Sbjct: 65 FRLFIGC--RLSFIDGTP--DMVVYPRDRAAYGQLCRLLTEGKHRAAIKGECHLEWADLL 120 Query: 133 APLAAHRHLRGLPDCLLILAPHYPADAATLERQARWLQETFPQRAWLGLTQLYRPFDALH 192 R + + P D + + + P WL LT ++ D Sbjct: 121 --------FRARQFQIAVFPPD--EDEPDFAARLTEIAQAAPGSVWLALTMPHQGQDGRR 170 Query: 193 RSVIDTVARRHGLPVTALGQVNMHVRSRKPLQDTLTAIRLGKAVSECGYDLAPNAEQHLR 252 I A + G+P+ A V H R+PLQD LTA R V G L NAE+HL+ Sbjct: 171 AERIARFAAQAGVPLIATNDVLYHHPDRRPLQDVLTATRHHTTVFAAGRLLEKNAERHLK 230 Query: 253 ---SRLRLANVFPASALQESLRIASLCHFKLSELRYEYPEELVPDGQTPAGYLRQEVYLG 309 +RL +P + + +A + F+L EL+Y YP+E +P G+T +L V+ G Sbjct: 231 PPHEMVRLFRDYPEAIAATADFVAPIT-FQLDELKYAYPDEPIPPGKTAQQHLYDLVWEG 289 Query: 310 AHLRYPAG-IPQKVIDQIEHELTLINDMAYEAYFLTVYDIVRFAKDQGILRQGRGSAANS 368 A Y A IP KV I EL LI + YE YFLTVYDIV A+++GIL QGRGSAANS Sbjct: 290 AARHYGADMIPPKVQGLINKELALIARLEYEPYFLTVYDIVTHAREKGILCQGRGSAANS 349 Query: 369 VVCYCLGVTEVDPTCSVMLFERFISKERGEPPDIDVDFEHQRREEVIQYIYRKYGRMRAA 428 VVC+CLG+T V+PT +LFERFIS ER EPPDIDVDFEH+RREEV+QY+Y +Y R RAA Sbjct: 350 VVCFCLGITGVNPTQVDLLFERFISAERKEPPDIDVDFEHERREEVMQYVYDRYSRDRAA 409 Query: 429 IAAAVHTYRPRGVLRDVGKALGVDASIVDKVAKSQQWFDSRDNMLERFAECGLDASSPIA 488 I A V +YR R +RDVGKALG+ + +A + + + GLD +PI Sbjct: 410 IVATVISYRSRSAIRDVGKALGLSEDVTAALANTVWGLSGGGIDRQHIRQAGLDPDNPII 469 Query: 489 QQWAMLALQLIKFPRHLSQHTGGFVIARHKLSRLVPIENAAMPERSVIQWDKDDLESLGL 548 Q+ LA+ LI FPRHLSQH GGFV+ R +L VPI AAM +RS I+WDKDD++ +GL Sbjct: 470 QRAVELAITLIGFPRHLSQHVGGFVLTRDRLDETVPIGPAAMDKRSFIEWDKDDIDEVGL 529 Query: 549 LKVDILALGMLSALRRALELVGQRR-----GAPFTMQDIPREDPATYDMICQADTVGVFQ 603 +KVD+L+LGML+ +R+A +L+ Q + G T+ +PR+D A YDM+C+ D++GVFQ Sbjct: 530 MKVDVLSLGMLTCIRKAFDLIHQHKPQLYGGEKLTLASLPRKDKAVYDMLCKGDSLGVFQ 589 Query: 604 IESRAQMSMLPRLQPRRFYDLVVQVAIVRPGPIQGGMVHPFLRRRAGEEAETYPK----- 658 +ESRAQM+MLPRL+P+ FYDLV++VAIVRPGPIQG MVHP+LRRR+G+E T P Sbjct: 590 VESRAQMNMLPRLRPQEFYDLVIEVAIVRPGPIQGDMVHPYLRRRSGQEPCTLPSPSPQH 649 Query: 659 ---EILRQALERTRGVPIFQEQVMQIAVLAAGFTPGEADGLRRAMAAWKRKGGMDKYQIK 715 L+Q L +T+GVP+FQEQ M+IA+ AA FTP EA+ LRRAMA +++ G + + K Sbjct: 650 GPANELQQILGKTKGVPLFQEQAMRIAMEAAKFTPEEANQLRRAMATFRKMGTIHTMEKK 709 Query: 716 LIDGMLARGYDKSFAEAIFRQIQGFGEYGFPESHAASFALLAYASSWIKCHEPEAFLCSL 775 +IDGM+ RGYD++FAE F QI+GFGEYGFPESHAASFA L Y S+W+KCH PE F +L Sbjct: 710 MIDGMVNRGYDRTFAENCFNQIKGFGEYGFPESHAASFAHLVYISAWLKCHHPEVFAAAL 769 Query: 776 LNSQPMGFYSPSQLIQDARRHGVQVLPADVMCSHWESTLEEIQAPRPAVRLGLSLLGSMR 835 LNSQPMGFY+P+Q+++DAR HGV VLP DV S W++ LEE A+RLG + Sbjct: 770 LNSQPMGFYAPAQIVRDAREHGVTVLPVDVNFSQWDNILEETPDVHLALRLGFRQIDGFS 829 Query: 836 EEAAQRIAQARRSAPFTDLPDLALRAHLDKRDLQALAAGNALHALSGNRREALWQALDAA 895 + + + A R P+ + D+ R LD+R LA +A +L +RR ALW A+ Sbjct: 830 KRDTELLI-ADRQEPYRTIEDMHRRLRLDRRAFTLLADADAFGSLDIDRRAALW-AVRRL 887 Query: 896 PTSD---LLRSAP----SREATLRLPPPSEAQDIVADYRSAGLTLRRHPLALLRPLLRKQ 948 P + L R+A ++E +LP + ++ ++ADY + L+L+ HPL LR L + Sbjct: 888 PNDETLLLFRAAAASELAQEPRTKLPEMAASEHVIADYETTRLSLKGHPLQYLREGLAAE 947 Query: 949 KFLSHEVMASFQDGQFARGCGIVTVRQRPGTAKGVLFLTIEDETGSTNVIVWPALVAKQR 1008 + + DG+ + G+VTVRQRPG+AKGV+FLTIEDETG N+++WP ++ R Sbjct: 948 GVSTCRAVQEGADGRRMKVAGVVTVRQRPGSAKGVVFLTIEDETGIANIVIWPKIMKVFR 1007 Query: 1009 NEVLNASLLGVYG-IWQSHAGVKHLVAKRLVDLSHLLGDIS 1048 EV++A L+ + G I +S GV HLVA +L D S L ++S Sbjct: 1008 REVMSARLIHIEGRIQRSLEGVVHLVAAKLQDRSAALIEMS 1048