BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4171.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 307 2e-83 YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 283 4e-76 yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 273 4e-73 ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 273 4e-73 ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 273 4e-73 >PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 307 bits (787), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 159/292 (54%), Positives = 205/292 (70%), Gaps = 2/292 (0%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGMVALSQSAASASLNELESLLGVQLFDRVGKRLVLN 60 M ++ RQLQIF AVA+ GSTTAAA ++LSQSA SA+LNELES L +LFDRVGKRL LN Sbjct: 1 MALSFRQLQIFCAVARCGSTTAAAESISLSQSATSAALNELESQLSTRLFDRVGKRLQLN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAA-GSELHLGASTTIGSYLLPAMIAAYRRIHAG 119 + GR+ LPQA +LD +E+QF+ AA + L + AS+TIG+Y+LP ++A++ R G Sbjct: 61 EVGRRFLPQALRLLDGVAQLEQQFAVSAAPQASLTVAASSTIGNYVLPRLLASFEREQPG 120 Query: 120 ARVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVRVEPWMTDELIVVAAPTHPIVAQA 179 RV A + NT V+ VV F D GLIEGPCH +RVEPW+ D LIVVAAP HP+ ++ Sbjct: 121 VRVNASIGNTGSAVQDVVTFAADIGLIEGPCHEPGLRVEPWLEDSLIVVAAPGHPLASRT 180 Query: 180 RKITLKMLRQADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +++ + LR+A WLLRE GSGTRE V HAL+ +LH+L S + G+SEAIK + A GLGIS Sbjct: 181 -QVSREALRRARWLLREPGSGTREEVSHALLGHLHYLEDSLDLGSSEAIKHSVAAGLGIS 239 Query: 240 CLSRSVVEDLIESGKLVELETPLPTLRRHFYMVVSRHRAPSPSLAALLSFCR 291 CLSR VVE+ + +G LVEL + LP LRR FYM+ R + SP CR Sbjct: 240 CLSRWVVEEQLATGALVELRSSLPPLRRRFYMLRQRDKFLSPGFERFWEHCR 291 >YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 290 Score = 283 bits (723), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 151/293 (51%), Positives = 197/293 (67%), Gaps = 6/293 (2%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGMVALSQSAASASLNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SA+L +LE LGVQLFDRVGKRLV N Sbjct: 1 MHITLRQLEVFTEVLKSGSTTQASVVLALSQSAVSAALADLEGQLGVQLFDRVGKRLVTN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQF-SDPAAGSELHLGASTTIGSYLLPAMIAAYRRIHAG 119 + GR L P+A +LD A IE+ F D A L + AS+TIG+Y+LP MIA YRR G Sbjct: 61 EHGRLLYPKALALLDQAIEIEQLFLHDLGA---LRIAASSTIGNYMLPGMIAKYRRDFPG 117 Query: 120 ARVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVRVEPWMTDELIVVAAPTHPIVAQA 179 + + N+ D++EAV +F D GLIEGPCH ++ + W+ DEL+V AAP P+ +A Sbjct: 118 TPLELNIGNSQDVIEAVADFRGDLGLIEGPCHMPELVTQNWLRDELVVFAAPDSPLCHKA 177 Query: 180 RKITLKMLRQADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +TL L ADW+LRE GSGTRE ++H L+ L H E GNSEAIKRA G+G+S Sbjct: 178 --LTLVDLADADWILRERGSGTREVLDHLLLAQLPHFKLVMELGNSEAIKRAVRYGMGVS 235 Query: 240 CLSRSVVEDLIESGKLVELETPLPTLRRHFYMVVSRHRAPSPSLAALLSFCRQ 292 CLSR V+ D + SG+LVEL PLP L R Y++ R + S +L LS+C++ Sbjct: 236 CLSRRVIADQLASGELVELNIPLPPLIRTLYLIHHRQKHISNALLRFLSYCQE 288 >yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 293 Score = 273 bits (698), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 145/291 (49%), Positives = 197/291 (67%), Gaps = 6/291 (2%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGMVALSQSAASASLNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ M+ALSQSA SA+L +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSELHLGASTTIGSYLLPAMIAAYRRIHAGA 120 + GR L P+A +L+ A IE+ F + ++ AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGAIRIY--ASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVRVEPWMTDELIVVAAPTHPIVAQAR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAPT P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL---AR 175 Query: 181 -KITLKMLRQADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 240 CLSRSVVEDLIESGKLVELETPLPTLRRHFYMVVSRHRAPSPSLAALLSFC 290 CLSR V+ED +++G L E+ PLP L R + + R + S +L L +C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 273 bits (698), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 145/291 (49%), Positives = 197/291 (67%), Gaps = 6/291 (2%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGMVALSQSAASASLNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ M+ALSQSA SA+L +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSELHLGASTTIGSYLLPAMIAAYRRIHAGA 120 + GR L P+A +L+ A IE+ F + ++ AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGAIRIY--ASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVRVEPWMTDELIVVAAPTHPIVAQAR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAPT P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL---AR 175 Query: 181 -KITLKMLRQADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 240 CLSRSVVEDLIESGKLVELETPLPTLRRHFYMVVSRHRAPSPSLAALLSFC 290 CLSR V+ED +++G L E+ PLP L R + + R + S +L L +C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 293 Score = 273 bits (698), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 145/291 (49%), Positives = 197/291 (67%), Gaps = 6/291 (2%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGMVALSQSAASASLNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ M+ALSQSA SA+L +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSELHLGASTTIGSYLLPAMIAAYRRIHAGA 120 + GR L P+A +L+ A IE+ F + ++ AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGAIRIY--ASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVRVEPWMTDELIVVAAPTHPIVAQAR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAPT P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL---AR 175 Query: 181 -KITLKMLRQADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 240 CLSRSVVEDLIESGKLVELETPLPTLRRHFYMVVSRHRAPSPSLAALLSFC 290 CLSR V+ED +++G L E+ PLP L R + + R + S +L L +C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286