BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4162.p (220 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0328 [R] COG2945 Predicted hydrolase of the alpha/beta superf... 271 9e-73 NMA1086 [R] COG2945 Predicted hydrolase of the alpha/beta superf... 140 3e-33 NMB0868 [R] COG2945 Predicted hydrolase of the alpha/beta superf... 137 2e-32 XF1829 [R] COG2945 Predicted hydrolase of the alpha/beta superfa... 129 6e-30 PA4440 [R] COG2945 Predicted hydrolase of the alpha/beta superfa... 117 2e-26 >RSc0328 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily Rso Ralstonia solanacearum Length = 215 Score = 271 bits (693), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 137/220 (62%), Positives = 165/220 (75%), Gaps = 12/220 (5%) Query: 1 MNVYTQHFMIPGAVGQLECALDLPDPEQFAAPVGLALVAHPHPLYGGSMDNKVAQTLART 60 MNV+T +IPG VG ++ ++DLPD AAP GLALV HPHPL+GG+ DNKVAQTLART Sbjct: 1 MNVHTAERLIPGPVGNIDVSVDLPD----AAPRGLALVGHPHPLFGGTKDNKVAQTLART 56 Query: 61 FLALGYVAVRMNFRGVGKSEGVHDHGAGETDDMALLLQHMRTQ------YPDLPLALGGF 114 F+ LGY VR NFRGVGK+EG HD+G GE DDM +L MRTQ LPLALGGF Sbjct: 57 FVGLGYATVRPNFRGVGKTEGTHDNGIGEQDDMLAVLDWMRTQAEWSPEVATLPLALGGF 116 Query: 115 SFGTFVQAQLQQRLLQQDAATAAERLVLVGTAAGKWPMPPAPANTILIHGEQDDTIPLSA 174 SFG+FV +Q+ +RL + A T AERL LVGTA +W + P PA+TI+IHGE DDT+PL+A Sbjct: 117 SFGSFVVSQVARRLAE--AGTPAERLALVGTATSRWDVAPVPADTIVIHGELDDTVPLAA 174 Query: 175 VLDWARPQELPVVVIPGSDHFFHRKLQHIKNVVVESWHRR 214 VLDWARPQELPV+VIPG+DHFFHRKL I+ + +W R Sbjct: 175 VLDWARPQELPVIVIPGADHFFHRKLHLIRQQIAGAWTPR 214 >NMA1086 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily NmA Neisseria meningitidis Z2491 Length = 213 Score = 140 bits (352), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 83/207 (40%), Positives = 116/207 (56%), Gaps = 17/207 (8%) Query: 10 IPGAVGQLECALDLPDPEQFAAPVGLALVAHPHPLYGGSMDNKVAQTLARTFLALGYVAV 69 I G G LE + +P EQ A G+A++ HP+PL GG+ NKV QT A+ LG+ Sbjct: 9 ISGPAGILE-TIHIPS-EQVPA-RGVAVINHPNPLQGGTNTNKVIQTAAKALSKLGFHCY 65 Query: 70 RMNFRGVGKSEGVHDHGAGETDDMALLLQHMRTQYPDLP-LALGGFSFGTFVQAQLQQRL 128 N RGVG SEG HD+G GET D ++ + R Q+P+ P AL GFSFG +V Q Sbjct: 66 LPNLRGVGGSEGTHDYGRGETQDCLAVIDYARAQHPEAPEFALSGFSFGGYVATFAAQ-- 123 Query: 129 LQQDAATAAERLVLVGTAAGKWPMPPAP------ANTILIHGEQDDTIPLSAVLDWARPQ 182 A + L+L+G A + P P A T++IHG +D+ + + L WA PQ Sbjct: 124 -----ARIPDLLLLIGAAVCHYTGRPEPSAVPNVAKTLMIHGAEDEVVEIGKALKWAEPQ 178 Query: 183 ELPVVVIPGSDHFFHRKLQHIKNVVVE 209 +LPV+ I GS HFFH KL +++ ++ Sbjct: 179 DLPVITIAGSTHFFHGKLIVLRDTILR 205 >NMB0868 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily Nme Neisseria meningitidis MC58 Length = 213 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 82/207 (39%), Positives = 115/207 (55%), Gaps = 17/207 (8%) Query: 10 IPGAVGQLECALDLPDPEQFAAPVGLALVAHPHPLYGGSMDNKVAQTLARTFLALGYVAV 69 I G G LE + +P EQ A G+A++ HP+PL GG+ NKV QT A+ LG+ Sbjct: 9 ISGPAGILE-TIHIPS-EQVPA-RGVAVINHPNPLQGGTNTNKVIQTAAKALSKLGFHCY 65 Query: 70 RMNFRGVGKSEGVHDHGAGETDDMALLLQHMRTQYPDLP-LALGGFSFGTFVQAQLQQRL 128 N RGVG S G HD+G GET D ++ + R Q+P+ P AL GFSFG +V Q Sbjct: 66 LPNLRGVGGSGGTHDYGRGETQDCLAVIDYARAQHPEAPEFALSGFSFGGYVATFAAQ-- 123 Query: 129 LQQDAATAAERLVLVGTAAGKWPMPPAP------ANTILIHGEQDDTIPLSAVLDWARPQ 182 A + L+L+G A + P P A T++IHG +D+ + + L WA PQ Sbjct: 124 -----ARTPDLLLLIGAAVCHYTDRPEPSAVPNVAKTLMIHGAEDEVVEIGKALKWAEPQ 178 Query: 183 ELPVVVIPGSDHFFHRKLQHIKNVVVE 209 +LPV+ I GS HFFH KL +++ ++ Sbjct: 179 DLPVITIAGSTHFFHGKLIVLRDTILR 205 >XF1829 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily Xfa Xylella fastidiosa 9a5c Length = 222 Score = 129 bits (324), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 76/211 (36%), Positives = 110/211 (52%), Gaps = 15/211 (7%) Query: 8 FMIPGAVGQLECALDLPDPEQFAAPVGLALVAHPHPLYGGSMDNKVAQTLARTFLALGYV 67 + G VG LE A+D P +A++ HP GGSMDNKV AR LG + Sbjct: 15 LFLEGPVGSLEVAVDFPG-FNVTTQSPVAIICHPLSTEGGSMDNKVVTMTARALRELGMM 73 Query: 68 AVRMNFRGVGKSEGVHDHGAGETDDMALLLQHMRTQYPDLPLALGGFSFGTFVQAQLQQR 127 VR NFR VG S+G+ D+G GE D+ + +R Q PD L L GFSFG ++ + + Sbjct: 74 TVRFNFRSVGASDGMFDNGHGERADLRAIAAWVRAQRPDSALWLAGFSFGAYISLLVAEE 133 Query: 128 LLQQDAATAAERLVLVGTAAGKWPMPPA--PANTILIHGEQDDTIPLSAVLDWAR--PQE 183 L Q L+ + AG+W P + +LI G+ D+ + AV DW P++ Sbjct: 134 LEPQ-------VLISISPPAGRWDFSHVHPPEHWLLIQGDADEVVDPQAVYDWISTLPRQ 186 Query: 184 LPVVVIPGSDHFFHRKLQHIKNVV---VESW 211 ++ +P + HFFHRKL H+++ + V SW Sbjct: 187 PKLIRMPDTSHFFHRKLIHLRDAIQDGVRSW 217 >PA4440 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily Pae Pseudomonas aeruginosa Length = 209 Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 78/194 (40%), Positives = 101/194 (52%), Gaps = 16/194 (8%) Query: 10 IPGAVGQLECA-LDLPDPEQFAAPVGLALVAHPHPLYGGSMDNKVAQTLARTFLALGYVA 68 I G G LE LDLPD G+ALV HPHPL+ G+M NKV TL R+ G Sbjct: 10 IDGPCGPLEALHLDLPDAR------GVALVCHPHPLFAGTMQNKVVATLQRSARDAGLAT 63 Query: 69 VRMNFRGVGKSEGVHDHGAGETDDMALLLQHMRTQYPDLPLALGGFSFGTFVQAQLQQRL 128 +R NFRGVG+S G + G GE DD + + ++P LPL L GFSFG+ V L RL Sbjct: 64 LRFNFRGVGQSAGSYGEGIGEIDDAEAAARWLLARHPGLPLTLMGFSFGSCVAGNLAGRL 123 Query: 129 LQQDAATAAERLVLVGTAAGKWPMP-PAPANTILIHGEQDDTIPLSAVLDW----ARPQE 183 Q A RL ++ ++ + PA ++ E DD + +AV W ARP E Sbjct: 124 EAQGVGLA--RLFMIAPPVERFAVSLPARCPLTVVQPEDDDVVTPAAVYAWSESLARPHE 181 Query: 184 LPVVVIPGSDHFFH 197 L + + S HFFH Sbjct: 182 L--LRVAESGHFFH 193