BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4011.p (459 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0387 [R] COG0612 Predicted Zn-dependent peptidases Rso Ralsto... 506 e-143 PA0372 [R] COG0612 Predicted Zn-dependent peptidases Pae Pseudom... 354 2e-97 BMEII1037 [R] COG0612 Predicted Zn-dependent peptidases Bme Bruc... 315 2e-85 mlr8255 [R] COG0612 Predicted Zn-dependent peptidases Mlo Mesorh... 293 4e-79 Cj0805 [R] COG0612 Predicted Zn-dependent peptidases Cje Campylo... 212 1e-54 >RSc0387 [R] COG0612 Predicted Zn-dependent peptidases Rso Ralstonia solanacearum Length = 501 Score = 506 bits (1304), Expect = e-143, Method: Compositional matrix adjust. Identities = 249/428 (58%), Positives = 308/428 (71%), Gaps = 5/428 (1%) Query: 32 FVLGNGLKLIVKQDRRAPTAVQMVWYKVGGIDELNGTTGVSHALEHMMFKGTKQHKVGEF 91 + L NGL+LIVK+D RAPT MVWY G IDE NGTTGV+H LEHMMFKGT+ GEF Sbjct: 63 YRLANGLRLIVKEDHRAPTVAHMVWYHAGSIDEHNGTTGVAHMLEHMMFKGTRAVGPGEF 122 Query: 92 SRLVAELGGQENAFTANDFTAYFQQIEKSHLEKVMALEADRMANLQFDANEFAKEIRVIM 151 SR VA LGG+ENA T DFT YFQQIEKSHL VMALEADRMANLQ EF E+ V+ Sbjct: 123 SRRVAALGGRENAMTTRDFTMYFQQIEKSHLADVMALEADRMANLQLTDKEFKPEMNVVK 182 Query: 152 EERRWRTDDQPMGLLNEALNAAAWTAHPYHHPVVGWMDDLQHMTVQDIAHWYRQWYAPNN 211 EERR R DD + E + A + A PY +P +GW DL MTVQD WY +WYAPNN Sbjct: 183 EERRMRIDDSARATVYEQMLAVLFNAAPYRNPTIGWPSDLDTMTVQDAQDWYHKWYAPNN 242 Query: 212 ATLVVAGDVEPQRVLALARKYFGKIPAHPLPQGKPQNEPEQRGMRRVTVKAPAENPYVVM 271 AT+VV GDV P V A++ +GK+ H LP+ Q+EP+Q G++R+ VKAPAENPYVV+ Sbjct: 243 ATVVVTGDVNPDEVFRQAQRTYGKLQPHALPRRYAQDEPKQVGVKRIWVKAPAENPYVVL 302 Query: 272 AWKVPALRQVEADQDAYALDVLSAVLDGYDNSRLSAQLVRTASK-----ATAVGASYSGV 326 A+K P LR VE D D YAL+VLSAVLDGYDN+RL LV+ + A V A Y G+ Sbjct: 303 AYKAPPLRDVEKDVDPYALEVLSAVLDGYDNARLPNLLVKGKDEKGGRLADDVNAGYDGM 362 Query: 327 ARGPVLFTLEGSPADGVSTEELEGLLRAEVERIAREGVSEQELQRVKRQLIASQIYKRDS 386 RGP +F L+G PADG +T E+E LRA+++RIAR+GV+E EL+RVK Q++A+QIYKRDS Sbjct: 363 NRGPSIFLLDGVPADGHTTAEIEQALRAQIDRIARDGVTEAELKRVKAQVVAAQIYKRDS 422 Query: 387 VFGQAMEMGMMETIGLGQQNIDRLIERLKSVSAAQVQAVAQKYFKDDTLTVATLVPLPLE 446 VFGQ ME+GM E GL +++DR++E++KSV+ AQVQ VA+ YF +D L VATL+P P++ Sbjct: 423 VFGQGMEIGMAEMTGLSWRDLDRILEKIKSVTPAQVQQVAKTYFTEDNLVVATLLPQPID 482 Query: 447 GKKPAAPP 454 KPA P Sbjct: 483 PNKPARKP 490 >PA0372 [R] COG0612 Predicted Zn-dependent peptidases Pae Pseudomonas aeruginosa Length = 465 Score = 354 bits (908), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 178/427 (41%), Positives = 263/427 (61%), Gaps = 2/427 (0%) Query: 25 QAEPAQAFVLGNGLKLIVKQDRRAPTAVQMVWYKVGGIDELNGTTGVSHALEHMMFKGTK 84 + +P F L NGLK+IV++D RAP V +WY++G E G TG+SHALEHMMFKG++ Sbjct: 35 ETQPTHEFSLDNGLKVIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSR 94 Query: 85 QHKVGEFSRLVAELGGQENAFTANDFTAYFQQIEKSHLEKVMALEADRMANLQFDANEFA 144 + GE SR++ +LG +ENAFT +D+TAY+Q + + L + +EADRMA+L ++F Sbjct: 95 KLGPGEASRVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFK 154 Query: 145 KEIRVIMEERRWRTDDQPMGLLNEALNAAAWTAHPYHHPVVGWMDDLQHMTVQDIAHWYR 204 EI VI EERR RTDD P L E AAA+ A YH P +GWM DLQ MT+ D+ HWY Sbjct: 155 SEIEVIKEERRLRTDDNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLRHWYE 214 Query: 205 QWYAPNNATLVVAGDVEPQRVLALARKYFGKIPAHPLPQGKPQNEPEQRGMRRVTVKAPA 264 WYAPNNATLVV GDV V LA++YFG+IP LP + E + G RR+ + Sbjct: 215 SWYAPNNATLVVVGDVTADEVKTLAKRYFGEIPWRQLPPARKPLELAEPGERRLKLYVRT 274 Query: 265 ENPYVVMAWKVPALRQVEADQDAYALDVLSAVLDGYDNSRLSAQLVRTASKATAVGASYS 324 + P ++M + VP+L E ++ AL ++ A+LDG ++RL+++L R Y Sbjct: 275 QLPNLIMGFNVPSLGSSENPREVNALRLIGALLDGGYSARLASRLERGEELVAGASTYYD 334 Query: 325 GVARGPVLFTLEGSP--ADGVSTEELEGLLRAEVERIAREGVSEQELQRVKRQLIASQIY 382 RG LF L +P G + E++E L +++ + + S E++RV+ Q+IA +Y Sbjct: 335 AFNRGDSLFVLSATPNVQKGKTLEQVEAGLWKQLDDLKQNPPSAAEIERVRAQMIAGMVY 394 Query: 383 KRDSVFGQAMEMGMMETIGLGQQNIDRLIERLKSVSAAQVQAVAQKYFKDDTLTVATLVP 442 ++DS+ QA +G +E++GL + ID+ +E LK+V+ +Q A+ YF LT+A ++P Sbjct: 395 EKDSIAAQASSIGQLESVGLSWKLIDQDLEALKAVTPDDIQKAARTYFTPSRLTLAQVLP 454 Query: 443 LPLEGKK 449 + E K+ Sbjct: 455 VKAEEKE 461 >BMEII1037 [R] COG0612 Predicted Zn-dependent peptidases Bme Brucella melitensis Length = 464 Score = 315 bits (806), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 175/434 (40%), Positives = 250/434 (57%), Gaps = 13/434 (2%) Query: 32 FVLGNGLKLIVKQDRRAPTAVQMVWYKVGGIDELNGTTGVSHALEHMMFKGTKQHKVGEF 91 F L NG++++V D RAP QMVWY VG DE G +G++H LEH+MFKGTK H GEF Sbjct: 18 FTLPNGMQVVVIPDHRAPVVTQMVWYHVGAADEAPGVSGIAHFLEHLMFKGTKNHPAGEF 77 Query: 92 SRLVAELGGQENAFTANDFTAYFQQIEKSHLEKVMALEADRMANLQFDANEFAKEIRVIM 151 S +A +GGQENAFT+ D+TAYFQ++ LE VM E+DRM NL D E VI+ Sbjct: 78 SARIASIGGQENAFTSYDYTAYFQRVSPEALEMVMDFESDRMENLVLDEEAVKTEREVIL 137 Query: 152 EERRWRTDDQPMGLLNEALNAAAWTAHPYHHPVVGWMDDLQHMTVQDIAHWYRQWYAPNN 211 EERR R D P +L E +A + HPY PV+GW +++ +++++ +Y Q+Y PNN Sbjct: 138 EERRMRIDSNPGAMLMENTDAVLFYNHPYRKPVIGWQQEMEKLSLKNAIDFYNQYYTPNN 197 Query: 212 ATLVVAGDVEPQRVLALARKYFGKIP--AHPLPQGKPQNEPEQRGMRRVTVKAP-AENPY 268 ATLV+AGDV P+RV LA K + + A L + +PQ EP + R VT+ P Sbjct: 198 ATLVIAGDVTPERVRELAMKTWANVHKRAEVLLRERPQ-EPAKHAARVVTLHDERVSTPS 256 Query: 269 VVMAWKVPALRQVE-----ADQDAYALDVLSAVLDGYDNSRLSAQLVRTASKATAVGASY 323 ++W VP+ + DA ALD+LS +L G SRL QL+ A GASY Sbjct: 257 FRISWLVPSYANEKRFANVKPGDAPALDLLSEILGGSQLSRLYQQLIVKQGIAAETGASY 316 Query: 324 SGVARGPVLFTLEGSPADGVSTEELEGLLRAEVERIAREGVSEQELQRVKRQLIASQIYK 383 G A F++ G P +G S ++E + A+V+RI R+GV++ EL + + + + + I+ Sbjct: 317 DGDALDDGTFSVYGVPRNGASLGDVEKAVAAQVDRIIRDGVTQAELDQARNRFLKAVIFA 376 Query: 384 RDSVFGQAMEMGMMETIGLGQQNIDRLIERLKSVSAAQVQAVAQKYFKDDTLTVATLVPL 443 RDS G A G ++G +I + + +KSV+ Q++ VA++Y D + L+P Sbjct: 377 RDSQTGMARIYGSALSVGQTVDDIQKWPDLIKSVTVDQIKDVARRYLVKDQAVTSYLLPP 436 Query: 444 PLEG----KKPAAP 453 E KKP AP Sbjct: 437 DTEAESARKKPNAP 450 >mlr8255 [R] COG0612 Predicted Zn-dependent peptidases Mlo Mesorhizobium loti Length = 462 Score = 293 bits (751), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 161/413 (38%), Positives = 232/413 (56%), Gaps = 3/413 (0%) Query: 32 FVLGNGLKLIVKQDRRAPTAVQMVWYKVGGIDELNGTTGVSHALEHMMFKGTKQHKVGEF 91 F+L NG++++V D RAP MVWYK+G DE G +G++H EH+MFK T H GEF Sbjct: 45 FLLDNGMEVVVIPDHRAPIVTHMVWYKIGSADEPPGKSGIAHFFEHLMFKATTNHAAGEF 104 Query: 92 SRLVAELGGQENAFTANDFTAYFQQIEKSHLEKVMALEADRMANLQFDANEFAKEIRVIM 151 R V+++GG NAFT+ D+TA+ + + S LE++M EADRM NL + E VI+ Sbjct: 105 DRAVSDIGGSNNAFTSYDYTAFHETVAPSALEQMMGFEADRMRNLILTDDVIKTERDVIL 164 Query: 152 EERRWRTDDQPMGLLNEALNAAAWTAHPYHHPVVGWMDDLQHMTVQDIAHWYRQWYAPNN 211 EERR R D+ P +L+E ++A W PY PV+GWM +++ + D +Y ++Y PNN Sbjct: 165 EERRSRIDNNPQAVLDEEVDATLWQNQPYRIPVIGWMQEMEQLNRTDAVAFYDKYYRPNN 224 Query: 212 ATLVVAGDVEPQRVLALARKYFGKIPAHP-LPQGKPQNEPEQRGMRRVTV-KAPAENPYV 269 A L+VAGDVEP+ V ALA K +GK+ P LP EPEQ R VT+ A P Sbjct: 225 AVLIVAGDVEPETVKALAEKTYGKVARGPDLPPRIRPVEPEQNTKRTVTLADARVSVPSF 284 Query: 270 VMAWKVPALRQVEADQDAYALDVLSAVLDGYDNSRLSAQLVRTASKATAVGASYSGVARG 329 W VP+ + + A ALD+L+ +L G + SRL LV A+ GA + G Sbjct: 285 STQWVVPSYHTAKPGE-AEALDLLAEILGGGNRSRLYQALVVKQGIASNAGAYFQGTMLD 343 Query: 330 PVLFTLEGSPADGVSTEELEGLLRAEVERIAREGVSEQELQRVKRQLIASQIYKRDSVFG 389 FT+ G+P ++E + AEV RIA GV+ EL++ K + I S ++ RD Sbjct: 344 DTNFTVYGAPRGDAKLADVEAAVDAEVARIASGGVTPDELEKAKDRYIRSMVFARDKQDS 403 Query: 390 QAMEMGMMETIGLGQQNIDRLIERLKSVSAAQVQAVAQKYFKDDTLTVATLVP 442 A G G Q++ + +R++ V+A +V+AVA +Y T L+P Sbjct: 404 MAEIYGSTLATGGNVQDVQQWPDRIRKVTADEVKAVAARYLVLARSTSGYLLP 456 >Cj0805 [R] COG0612 Predicted Zn-dependent peptidases Cje Campylobacter jejuni Length = 416 Score = 212 bits (540), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 123/396 (31%), Positives = 214/396 (54%), Gaps = 26/396 (6%) Query: 55 VWYKVGGIDELNGTTGVSHALEHMMFKGTKQHKVGEFSRLVAELGGQENAFTANDFTAYF 114 ++YKVG +E+ G +G++H LEH+ FK TK K GEF +V GG +NA T D+T Y+ Sbjct: 31 IFYKVGSRNEIMGKSGIAHMLEHLNFKSTKNLKAGEFDEIVKGFGGVDNASTGFDYTHYY 90 Query: 115 QQIEKSHLEKVMALEADRMANLQFDANEFAKEIRVIMEERRWRTDDQPMGLLNEALNAAA 174 + K +L+K + L A+ MANL EF E V++EERRWRTD+ P+G L L A Sbjct: 91 IKCAKKNLDKALELFAELMANLNLKDEEFQPERAVVLEERRWRTDNNPLGYLYFRLFNHA 150 Query: 175 WTAHPYHHPVVGWMDDLQHMTVQDIAHWYRQWYAPNNATLVVAGDVEPQRVLALARKYFG 234 + HPYH +G+ D+++ +++DI ++ +Y P NA L+V+GD+E + V L++K+F Sbjct: 151 FMYHPYHWTPIGFFKDIENWSIEDIKEFHSIYYQPKNAILLVSGDIESKEVFELSKKHFE 210 Query: 235 KIP-AHPLPQGKPQNEPEQRGMRRVTVKAPAENPYVVMAWKVPALRQVEADQDAYALDVL 293 KI +P+ + EP+Q G++R+ + ++ + +A+K+P + +D AL+ L Sbjct: 211 KIKNTKTIPKIHTK-EPKQDGVKRIYLHKNSDTELLALAYKIPNFKH----KDIPALNAL 265 Query: 294 SAVLDGYDNSRLSAQLVRTASKATAVGASYS----GVARGPVLFTLEGSPADGVSTEELE 349 S +L +S +S L+ K + Y+ + +F +P V+ E++E Sbjct: 266 SELLGSGKSSLMSEILI---DKLNLINDYYAYVNDCIDENLFIFICNCNP--NVNAEKVE 320 Query: 350 GLLRAEVERIAREGVSEQELQRVKRQLIASQIYKRDSVFGQAMEMGMMETIG--LGQQNI 407 L ++++ +S+++LQRVK + K D +F + G L + +I Sbjct: 321 KELLKIIDKLKMGKISQKDLQRVKNNV------KSDFIFSLNNASAVANIYGSYLARGDI 374 Query: 408 DRLIERLKSVSAAQVQ---AVAQKYFKDDTLTVATL 440 + L+ K + +++ + A+KYF + T L Sbjct: 375 NPLLNYEKDIQNLELKDLISCAKKYFIQENSTTVIL 410