BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4005.p (296 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1395 [GER] COG0697 Permeases of the drug/metabolite transport... 122 8e-28 mlr0335 [GER] COG0697 Permeases of the drug/metabolite transport... 50 6e-06 MA1667 [GER] COG0697 Permeases of the drug/metabolite transporte... 45 3e-04 BMEI0982 [GER] COG0697 Permeases of the drug/metabolite transpor... 44 5e-04 yijE [GER] COG0697 Permeases of the drug/metabolite transporter ... 39 0.021 >RSc1395 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 306 Score = 122 bits (307), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 104/279 (37%), Positives = 151/279 (54%), Gaps = 14/279 (5%) Query: 12 LLLNTTIWGLSWTGTRALEGMGLHPVWATA---AIFGLCALLLLTLRYRDLPQLWRHPAL 68 +L+ ++WG+SW R L G GL + A+A A + A + L + W PAL Sbjct: 24 ILVGASVWGISWYPYRLLAGWGLGSLLASAMTGAAATIVAAVALRRHFHTFRWSWLIPAL 83 Query: 69 LCVGLATGLTNCAFNVAVAYGDVVRVVLLFYLMPVWTVILARLVLHEAITPRSLARVALG 128 GL G+TN F + +G V+RV+LLFYL P+WT +LARL LHE + R A + + Sbjct: 84 ---GLVAGVTNAGFVWSTVHGTVMRVLLLFYLTPLWTALLARLWLHERLGARGAALLVVA 140 Query: 129 LGGAFIVLYQPRLGIPLPRSLPDWMALAAGLLFAFTNVLLR----RMHGLSSDGARAVAM 184 L GA ++L G+P P + +W + AGL FA NVL R R+ + ++ R V + Sbjct: 141 LCGAGLMLGAGNAGMPWPGTAAEWSGVVAGLAFACNNVLARLVGQRLPTMRAE-LRTVVV 199 Query: 185 LAGSGLLATLLGLLLSLLGMIAWPLQVSAAAA-PVVGVWALLFLFSNLCLQYGVSRLPAN 243 AGS L+ + L G+ A P ++ A +VG A + + N +Q G+ RLPAN Sbjct: 200 FAGSALVGLPAAIWLD--GVQAVPDALATADVWLLVGGMAAVLVAGNTLVQRGLQRLPAN 257 Query: 244 ITAVVMLTEILVASLSSWALGAAELRVQDLVGGILIIAA 282 A++ML EI+VA+ SS L A L Q++ GG II A Sbjct: 258 RAALLMLFEIVVAAASSAWLTAERLSAQEMAGGACIILA 296 >mlr0335 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 290 Score = 50.1 bits (118), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 52/170 (30%), Positives = 80/170 (47%), Gaps = 11/170 (6%) Query: 8 AVAALLLNTTI-WGLSWTGTRALEGMGLHPVW---ATAAIFGLCALLLLTLRYRDLPQLW 63 AVAA+++ T WGL++ + + G PV+ A + I G C + L R+R + Sbjct: 2 AVAAIMVGLTFSWGLNYVAAK-ISYAGYDPVFLSIARSIIGGFC--VFLWCRWRGIALFT 58 Query: 64 RHPALLC---VGLATGLTNCAFNVAVAYGDVVRVVLLFYLMPVWTVILARLVLHEAITPR 120 R LL VG+ G+ V + + V R LL MP W +I L+L E IT R Sbjct: 59 RDGTLLAGIAVGVLFGIEFLCLYVGLEHTTVARNTLLVNSMPFWMLIGGHLLLGEQITMR 118 Query: 121 SLARVALGLGGAFIVLYQPRLGIPLPRSLPDWMALAAGLLFAFTNVLLRR 170 + L G V + +LG D ++L +G +A TN+L++R Sbjct: 119 KFLGLLLAFAGLAAV-FSDKLGGGGDMLFGDLLSLGSGFFWALTNILIKR 167 >MA1667 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mac Methanosarcina acetivorans str.C2A Length = 346 Score = 44.7 bits (104), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 72/311 (23%), Positives = 127/311 (40%), Gaps = 38/311 (12%) Query: 1 MQHLP------KPAVAALLLNTTIWGLSWTGTRALEGMGLHPVWATAAIFGLCALLLLTL 54 Q++P KP + ++ + I+G ++ M + V FGLC + L Sbjct: 39 FQNMPAQKNSFKP-YSEVITGSIIYGTMGVFLDRVQDMSVGSVLFCRLFFGLCMIFFYLL 97 Query: 55 RYRDLPQL---WRHPALLCVGLATGLTNCAFNVAVAYGDVVRVVLLFYLMPVWTVILARL 111 L QL LL +G +T + A+ Y + VLL Y PV+ +LA Sbjct: 98 LSGSLEQLRPGKNRKYLLLLGFLNAVTGVCYLSAIRYSGISVAVLLLYTAPVYVNLLAPS 157 Query: 112 VLHEAITPRSLARVALGLGGAFIVLYQPRLGIPLPRSLPDWM-----ALAAGLLFAFTNV 166 +L E + +SL + L L G ++ +P + D+M L +GL F T + Sbjct: 158 ILGEKSSSKSLLPLFLSLAGVLLIA-RPGEVLGSLNEGADFMKGLSFGLISGLSFGATII 216 Query: 167 LLRRMHGLSSDGARAVAMLAGSGLLATLLGLLLSLLGMIAWPLQVSAAAAPVVGVWALLF 226 +R + G L G +SLL M+ P ++ +G ++ LF Sbjct: 217 TIRYLRH-DYTGISQTFWLTG-----------ISLLFML--PSALTTPMYTYIGNFSTLF 262 Query: 227 LFSNLCLQY-------GVSRLPANITAVVMLTEILVASLSSWALGAAELRVQDLVGGILI 279 LF L + + G+S + A +++ L E + A+ L + +G +LI Sbjct: 263 LF-GLTITFAAILYLKGISGIRAQTGSILALLEPVSGIFFDTAVLKNPLYISTFLGCVLI 321 Query: 280 IAAPWIVRERQ 290 + A ++V ++ Sbjct: 322 LTAAYLVSRKK 332 >BMEI0982 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 307 Score = 43.9 bits (102), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 11/172 (6%) Query: 8 AVAALLLNTTIWGLSWTGTRALEGMGLHPVWATA---AIFGLCALLLLTLRYRDLPQLWR 64 A+A ++ WGL+ + + G +P+ A A+ GLC L +R +P R Sbjct: 19 AIALVIFIMFGWGLNQVAIK-IGNWGFNPMLMAAGRSALGGLCVFLWCC--WRRIPLFKR 75 Query: 65 HPAL---LCVGLATGLTNCAFNVAVAYGDVVRVVLLFYLMPVWTVILARLVLHEAITPRS 121 L L G+ G VA+ V RV L+ +MP W I + +L E ++ R+ Sbjct: 76 DDTLKPGLVAGMLFGTEFVLIFVAMDLTSVGRVTLMMNVMPFWVAIGSHFLLGERMSVRA 135 Query: 122 LARVALGLGGAFIVLYQPRLGIPLPRSL-PDWMALAAGLLFAFTNVLLRRMH 172 + + G F+V + + P P + D +AL +G+L+ T ++++R Sbjct: 136 FIGMCIAFFGVFLV-FSDYVSRPGPYAFYGDLLALFSGVLWGLTTLVIKRTK 186 >yijE [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 312 Score = 38.5 bits (88), Expect = 0.021, Method: Compositional matrix adjust. Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 5/135 (3%) Query: 8 AVAALLLNTTIWGLSWTGTRALEG-MGLHPVWATAAIFG-LCALLLLTLRYRDL-PQLWR 64 A++ L++ T IW SW + + +G A IFG L ++L LR R + P ++ Sbjct: 22 AISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRGRGMRPTPFK 81 Query: 65 HPALLCVGLATGLTNCAFNVAVAYGDVVRVVLLFYLMPVWTVILARLVLHEAITPRSLAR 124 + + + G+ A A+ G +V +L Y MP W VI A L L E + Sbjct: 82 YTLAIALLQTCGMVGLA-QWALVSGGAGKVAILSYTMPFWVVIFAALFLGERLRRGQYFA 140 Query: 125 VALGLGGAFIVLYQP 139 + + G F+VL QP Sbjct: 141 ILIAAFGLFLVL-QP 154