BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4003.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3157 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto... 458 e-129 FN0778 [QR] COG0500 SAM-dependent methyltransferases Fnu Fusobac... 126 5e-29 CAC0151 [QR] COG0500 SAM-dependent methyltransferases Cac Clostr... 120 4e-27 MK0845 [QR] COG0500 SAM-dependent methyltransferases Mka Methano... 57 5e-08 VC1906 Non COG 45 1e-04 >RSc3157 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia solanacearum Length = 278 Score = 458 bits (1178), Expect = e-129, Method: Compositional matrix adjust. Identities = 224/275 (81%), Positives = 241/275 (87%), Gaps = 2/275 (0%) Query: 25 QAHEIRPGQSIELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEVLADHPDVSL 84 + HEIRP QSIELLKELHILTRDGK+NQDSRRKLKQVYHL+QFIEPLL +V VSL Sbjct: 4 KTHEIRPNQSIELLKELHILTRDGKMNQDSRRKLKQVYHLFQFIEPLLDDVQKAKGHVSL 63 Query: 85 VDHGAGKSYLGFILYDLFFKGLAG--APHIYGIETREELVRKSEELAARLGFGGMSFLNL 142 VDHGAGKSYLGFILYDLFFK G A HIYGIETRE LV KS ELAARLGF GMSFLN+ Sbjct: 64 VDHGAGKSYLGFILYDLFFKEQPGDGASHIYGIETREALVAKSTELAARLGFKGMSFLNV 123 Query: 143 SVADSISSPSLPDNIDVVTALHACDTATDDAIHFALAKQARFIVLVPCCQAEVASVLNRN 202 SVA+SI+S LP +DVVTALHAC+TATDDAI FAL K A++IVLVPCCQAEVA VL RN Sbjct: 124 SVAESITSERLPPAVDVVTALHACNTATDDAIRFALEKHAQYIVLVPCCQAEVAGVLRRN 183 Query: 203 KGKSLANSLTEIWRHPLHTREFGSQVTNVLRCLQLEAHGYKVSVTELVGWEHSMKNELII 262 KGKSL N+LTEIWRHPLHTREFGSQVTNVLRCLQLEAHGY+VSVTELVGWEHSMKNELI+ Sbjct: 184 KGKSLGNALTEIWRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEHSMKNELIV 243 Query: 263 AQYRDLPRRRPAERLQEVLRTLGLEEMQTRFFASA 297 AQY+DLPRRRP ERL EVL TLGLEE++ RFFA A Sbjct: 244 AQYKDLPRRRPTERLAEVLSTLGLEELRERFFAPA 278 >FN0778 [QR] COG0500 SAM-dependent methyltransferases Fnu Fusobacterium nucleatum Length = 412 Score = 126 bits (317), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 84/289 (29%), Positives = 151/289 (52%), Gaps = 23/289 (7%) Query: 22 SAPQAHEIRPGQSIELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEV-----L 76 + + + + G I+ L EL +++ +GK+ + S K KQ+ +FI+ ++ E+ + Sbjct: 120 NKKKQYILNEGDKIDFLIELGLMSVEGKILKSSYNKFKQINKYLEFIDDVIVELKTKKLI 179 Query: 77 ADHPDVSLVDHGAGKSYLGFILYDLFFKGLAG--APHIYGIETREELVRKSEELAARLGF 134 +H ++++D G GKSYL F LY + K + I G++ +++++ +LA +L + Sbjct: 180 NNH--INILDFGCGKSYLTFALY-YYLKNYRKDLSFSIVGLDLKKDVIEFCNKLAQKLSY 236 Query: 135 GGMSFLNLSVADSISSPSLPDNIDVVTALHACDTATDDAIHFALAKQARFIVLVPCCQAE 194 + FLN ++ D + +D+V +LHAC+ ATD ++ AL+ A+ I+ VPCC E Sbjct: 237 ENLEFLNGNIKDYDRAKE----VDLVFSLHACNNATDYSLEKALSLNAKAILAVPCCHHE 292 Query: 195 VASVLNRNKGKSLANSLTEIWRHPLHTREFGSQVTNVLRCLQLEAHGYKVSVTELVGWEH 254 + +NK ++L I + + +F S T+ R L LE GYK + E + EH Sbjct: 293 FFEKIQKNKDSKFYDTLKIIADNGIVLDKFASLATDSFRSLTLELCGYKTKMIEFIDMEH 352 Query: 255 SMKNELI--IAQYRDLPRRRPAERLQE---VLRTLG----LEEMQTRFF 294 + KN LI I + E+L+E + + LG LEE+ ++F Sbjct: 353 TPKNILIKAIKSRSSNLKENLKEKLKEYNSLKKFLGIQPLLEELTKKYF 401 >CAC0151 [QR] COG0500 SAM-dependent methyltransferases Cac Clostridium acetobutylicum Length = 386 Score = 120 bits (301), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 75/234 (32%), Positives = 121/234 (51%), Gaps = 14/234 (5%) Query: 29 IRPGQSIELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEVLADHPDVSLVDHG 88 I+ G + +LLK + I+T+D K+ D RK Q+ H + I+ L + + + ++++D G Sbjct: 130 IKIGPANDLLKAIDIMTKDNKVKNDKIRKYNQIDHFIELIDSTLDSI-SRNKHITILDCG 188 Query: 89 AGKSYLGFILYDLFFKGLAGAPHIYGIETREELVRKSEELAARLGFGGMSFLNLSVADSI 148 GKSYL F L + GI+ E +++KS+ +A LG+ M F + + D Sbjct: 189 CGKSYLTFALNYYLTEVKKVKCSFIGIDISEAVIQKSKSIAQTLGYRNMDFYAMDIHDY- 247 Query: 149 SSPSLPD-NIDVVTALHACDTATDDAIHFALAKQARFIVLVPCCQAEVASVLNRNKGKSL 207 PD I++V +LHACDTATD A+ + ++ I+ VPCC E+ S + K Sbjct: 248 ----KPDRKINMVISLHACDTATDMALALGIRLESDAIIAVPCCHKEMLSQYSYEPFK-- 301 Query: 208 ANSLTEIWRHPLHTREFGSQVTNVLRCLQLEAHGYKVSVTELVGWEHSMKNELI 261 +I +H + F +T+ +R L LEA GY V+ E + + KN LI Sbjct: 302 -----DILKHGIFKARFADVLTDGMRSLMLEAKGYDVTPVEYISPLETPKNLLI 350 >MK0845 [QR] COG0500 SAM-dependent methyltransferases Mka Methanopyrus kandleri AV19 Length = 229 Score = 57.0 bits (136), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 56/203 (27%), Positives = 85/203 (41%), Gaps = 24/203 (11%) Query: 51 NQDSRRKLKQVYHLYQFIEPLLQEVLADHPDVSLVDHGAGKSYLGFILYDLFFKGLAGAP 110 +D+ RK KQV + + L+ P ++VD G G+ L L Sbjct: 25 GRDAWRKKKQVETILTLLCSRLK------PGDTVVDCGCGRGTLTTALAVSSPSCDVLGF 78 Query: 111 HIYGIETREELVRKSEELAARLGFGGMSFLNLSVAD--SISSPSLPDNIDVVTALHACDT 168 I ET EL R E + G+ L V D + LPD+ DV+ LH C T Sbjct: 79 DIKEFETWTELERYVESV-------GLDNLEFEVNDLHETAKYGLPDDPDVIVGLHLCGT 131 Query: 169 ATDDAIHFALAKQARFIVLVPCCQAE-----VASVLNRNKGKSLANSLTEIWRHPLHTRE 223 TD + A+ A F+++VPCC + L ++G + E+ + + E Sbjct: 132 LTDRLLKLAVNSDAHFVLVVPCCYGRASPRVIVEELGVDEG---IERVREVLKRAESSVE 188 Query: 224 FGSQVTNVLRCLQLEAHGYKVSV 246 + +V +R LE HGY+V V Sbjct: 189 YQLEVCR-MRGKFLEEHGYQVHV 210 >VC1906 Non COG Length = 398 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 8/127 (6%) Query: 65 YQFIEPLLQEVLADHPDVSLVDHGAGKSYLGFILYDLFFKGLAGAPHIYGIETREELVRK 124 +Q IE + + ++A H ++ AGK YLG IL G+ P + E + EL Sbjct: 106 WQQIEAISKVLVAHHQGTQWLEWCAGKGYLGRIL-----AGVTQQP-VVSFEYQAELCCS 159 Query: 125 SEELAARLGFGGMSFLNLSVADSISSPSLPDNIDVVTALHACDTATDDAIHFALAKQARF 184 ++ A L M F+ D S+ + V ALHAC +H+A + A Sbjct: 160 GQQEADALQLP-MQFVQGDAFDERSAALFNSSTHAV-ALHACGDLHAKMLHYATSSHAAA 217 Query: 185 IVLVPCC 191 I PCC Sbjct: 218 ISFSPCC 224