BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.4002.p (262 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Esc... 280 2e-75 PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 232 8e-61 PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 216 4e-56 BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bm... 215 9e-56 BH0201 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bha B... 214 1e-55 >ydbS [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Eco Escherichia coli K12 Length = 255 Score = 280 bits (717), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 147/255 (57%), Positives = 188/255 (73%), Gaps = 1/255 (0%) Query: 8 DDILVARHGEQVLHLTLNRPAVRNALRNQSLQEIVQELARAEQDDSVRVVVISGNDQAFA 67 +++V+R ++VL LTLNRPA RNAL N L ++V EL A D S+ V VI+GN + FA Sbjct: 2 SELIVSRQ-QRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFA 60 Query: 68 AGADLNEMIHKDAIATQLDVRAQYWRAIARFPKPLLAAVNGYALGAGCELLMHADIAIAG 127 AGADLNEM KD AT D R Q W + F KPL+AAVNGYALGAGCEL + D+ +AG Sbjct: 61 AGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAG 120 Query: 128 RSARIGQPEINVGTLPGAGGTQRLIRTVGKPLAMKMVLSGEFITAEQALQAGLVAEVVED 187 +AR G PEI +G +PGAGGTQRLIR+VGK LA KMVLSGE ITA+QA QAGLV++V Sbjct: 121 ENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPS 180 Query: 188 EATLERSLALATRIAQKSPLAVRLAKEAMLQSFELGLEAGLLLERKSFSLMAASADRQEG 247 + TLE +L LA+++A+ SPLA++ AK+A+ QS E+ L+AGL ER+ F+L+AA+ DR EG Sbjct: 181 DLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEG 240 Query: 248 IAAFQEKRAAVFSGR 262 I+AF +KR F GR Sbjct: 241 ISAFLQKRTPDFKGR 255 >PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 261 Score = 232 bits (591), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 121/257 (47%), Positives = 166/257 (64%) Query: 6 PHDDILVARHGEQVLHLTLNRPAVRNALRNQSLQEIVQELARAEQDDSVRVVVISGNDQA 65 P +L+ + L LNRP RNAL ++ Q + D ++RV+V++G+ + Sbjct: 5 PSPVVLLEFPAADIALLRLNRPQARNALNDEVRQRLASHFQTLGADPAIRVIVLTGDSRC 64 Query: 66 FAAGADLNEMIHKDAIATQLDVRAQYWRAIARFPKPLLAAVNGYALGAGCELLMHADIAI 125 FAAGADL ++ AI +YW AIAR PKP++AAVNG+ALG GCEL MH D+ + Sbjct: 65 FAAGADLRDLSTSTAIGLYGRHGERYWEAIARCPKPVIAAVNGFALGGGCELAMHCDLIV 124 Query: 126 AGRSARIGQPEINVGTLPGAGGTQRLIRTVGKPLAMKMVLSGEFITAEQALQAGLVAEVV 185 AG SA+ QPEI VG +PGAGGTQRL+R VGK A++M+ +G + A QAL GLV+EVV Sbjct: 125 AGESAQFAQPEIKVGVMPGAGGTQRLVRAVGKFQALRMLFTGCLVKAPQALAMGLVSEVV 184 Query: 186 EDEATLERSLALATRIAQKSPLAVRLAKEAMLQSFELGLEAGLLLERKSFSLMAASADRQ 245 DE+TL R+L LA IA+ PLA+ KE +L +L L++ L LERK+F L+ S D++ Sbjct: 185 ADESTLARALELAMEIARLPPLALAQIKEVVLAGADLPLDSALALERKAFQLLFDSQDQK 244 Query: 246 EGIAAFQEKRAAVFSGR 262 EG+ AF EKR + G+ Sbjct: 245 EGMHAFLEKRPPNYQGK 261 >PA3591 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 265 Score = 216 bits (550), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 120/253 (47%), Positives = 166/253 (65%) Query: 10 ILVARHGEQVLHLTLNRPAVRNALRNQSLQEIVQELARAEQDDSVRVVVISGNDQAFAAG 69 +L+ R + V L LNRPAV NAL + + + + + R ++ RV+V++GN AFAAG Sbjct: 13 VLLERPEQGVALLRLNRPAVLNALNMRLREALAEHVRRLDECADTRVIVLTGNGTAFAAG 72 Query: 70 ADLNEMIHKDAIATQLDVRAQYWRAIARFPKPLLAAVNGYALGAGCELLMHADIAIAGRS 129 ADLNE+ A+ Q ++W+A+A KPL+AAV G+ALG GCEL MH D+ +AG S Sbjct: 73 ADLNELAEASALEIQQRGVERHWQALAACRKPLIAAVEGHALGGGCELAMHCDLIVAGAS 132 Query: 130 ARIGQPEINVGTLPGAGGTQRLIRTVGKPLAMKMVLSGEFITAEQALQAGLVAEVVEDEA 189 AR QPEI VG +PGAGGTQRL+R VGK A++M+ +G + A +AL GLV+EV D Sbjct: 133 ARFAQPEIRVGVMPGAGGTQRLVRAVGKFQALRMLFTGCTVRAPEALAIGLVSEVAADGQ 192 Query: 190 TLERSLALATRIAQKSPLAVRLAKEAMLQSFELGLEAGLLLERKSFSLMAASADRQEGIA 249 L+R+L LA +IA PLA+ KE +L +L L+ L LERK+F L+ S D++EG+ Sbjct: 193 ALDRALELARQIAGLPPLALAQIKEVVLAGADLPLDQALALERKAFQLLFDSHDQKEGMR 252 Query: 250 AFQEKRAAVFSGR 262 AF EKR A + G+ Sbjct: 253 AFLEKRTAEYLGK 265 >BMEII1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 261 Score = 215 bits (547), Expect = 9e-56, Method: Compositional matrix adjust. Identities = 115/253 (45%), Positives = 155/253 (61%) Query: 10 ILVARHGEQVLHLTLNRPAVRNALRNQSLQEIVQELARAEQDDSVRVVVISGNDQAFAAG 69 + V RH + V + +NRP RNAL + Q++ + D+SVR +V++G + F G Sbjct: 9 VSVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDG 68 Query: 70 ADLNEMIHKDAIATQLDVRAQYWRAIARFPKPLLAAVNGYALGAGCELLMHADIAIAGRS 129 AD+ E I L W AIA KP++AAVNGYALG GCEL MH DI +AG Sbjct: 69 ADVREFASAGPIEMYLRHTEYLWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEG 128 Query: 130 ARIGQPEINVGTLPGAGGTQRLIRTVGKPLAMKMVLSGEFITAEQALQAGLVAEVVEDEA 189 A GQPE+ +G +PGAGGTQRLIR VGK AM++ L+G + A +AL G+++E+ +E Sbjct: 129 AVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCMVPAAEALSIGMISEMTANER 188 Query: 190 TLERSLALATRIAQKSPLAVRLAKEAMLQSFELGLEAGLLLERKSFSLMAASADRQEGIA 249 TL R+ LA IA+ LAV KE ML +L L+ L LERK+F L+ S D++EG A Sbjct: 189 TLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAA 248 Query: 250 AFQEKRAAVFSGR 262 AF EKR ++GR Sbjct: 249 AFLEKRKPAYNGR 261 >BH0201 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bha Bacillus halodurans Length = 257 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 107/240 (44%), Positives = 164/240 (68%) Query: 22 LTLNRPAVRNALRNQSLQEIVQELARAEQDDSVRVVVISGNDQAFAAGADLNEMIHKDAI 81 + LNRP V NAL Q +QEIV++ R ++D +RV+++ G+++AFAAGAD+ EM + I Sbjct: 17 IQLNRPKVANALNRQMVQEIVEQAERYDRDQEIRVILVKGSERAFAAGADIREMEGETPI 76 Query: 82 ATQLDVRAQYWRAIARFPKPLLAAVNGYALGAGCELLMHADIAIAGRSARIGQPEINVGT 141 +L W R KP++AAV+G+ALG G EL +H D+ +A +AR G PE+++G Sbjct: 77 RFELADPFADWDRFTRIHKPMVAAVSGFALGGGFELALHCDLIVAATNARFGFPEVSLGV 136 Query: 142 LPGAGGTQRLIRTVGKPLAMKMVLSGEFITAEQALQAGLVAEVVEDEATLERSLALATRI 201 LPGAGGTQ L R VG+ A++ + +G+ I+A++ALQ G++ ++VE E E + LA I Sbjct: 137 LPGAGGTQLLTRAVGRKKALEWIWTGKHISAQEALQIGIINKIVEPELVEEEAFRLARTI 196 Query: 202 AQKSPLAVRLAKEAMLQSFELGLEAGLLLERKSFSLMAASADRQEGIAAFQEKRAAVFSG 261 +++P+AVRL KEA+ Q+ ++ L G++LERK+F L A+ D++EG+ AF EKR +F G Sbjct: 197 VKQAPIAVRLIKEAVHQAEDVTLADGMMLERKNFYLAFATKDQKEGMKAFLEKRPPIFKG 256