BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3988.p (686 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value maoC_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Esc... 508 e-143 SMb21635_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme... 499 e-140 DR2381_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Dra D... 477 e-134 DR2381_2 [I] COG2030 Acyl dehydratase Dra Deinococcus radiodurans 263 1e-69 maoC_2 [I] COG2030 Acyl dehydratase Eco Escherichia coli K12 227 6e-59 >maoC_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Escherichia coli K12 Length = 500 Score = 508 bits (1308), Expect = e-143, Method: Compositional matrix adjust. Identities = 281/503 (55%), Positives = 349/503 (69%), Gaps = 8/503 (1%) Query: 8 LQSFIAGRW-FGESPAQALHSAVNGHTVASTHAESIDFGEALDHARRQGLPGLMALDFQQ 66 L SF++G W G ++ +H A++G + +E +D A A +G P L A+ F + Sbjct: 4 LASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMTFIE 63 Query: 67 RAAILKALGKYLMEHKETLYAVSAHTGATRNDSWIDIEGGSGTLFAYASIGTNEFPSSNL 126 RAA+LKA+ K+L+ KE YA+SA TGATR DSW+DIEGG GTLF YAS+G+ E P L Sbjct: 64 RAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPDDTL 123 Query: 127 VHEGPALALGKQGRFSGTHILVPRGGVAVHINAFNFPIWGMLEKFAPSFLAGMPCIVKPA 186 E + L K+G F+ H+L + GVAVHINAFNFP WGMLEK AP++L GMP I+KPA Sbjct: 124 WPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAIIKPA 183 Query: 187 TATSYLTEAAVRLIQQSGLLPAGSLQLVIGATGDLLERLQAQDVVTFTGSADTAAKLRAH 246 TAT+ LT+A V+ I SGL+P G++ L+ G+ GDLL+ L +QDVVTFTGSA T LR Sbjct: 184 TATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSAATGQMLRVQ 243 Query: 247 PNLIANAIPFNAEADSLNCAILGPDVTADDEEFELFVKEVAREMSTKAGQKCTAIRRAIV 306 PN++A +IPF EADSLNC +LG DVT D EF LF++EV REM+TKAGQKCTAIRR IV Sbjct: 244 PNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEFALFIREVVREMTTKAGQKCTAIRRIIV 303 Query: 307 PRQHVDAVAERLAARLSKIVVGDPALESVRMGPLASKAQQRDVEERVT-LLKQGAEVILG 365 P+ V+AV++ L ARL K+VVGDPA E V+MG L + Q+ DV+E+V LL G E+ LG Sbjct: 304 PQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNILLAAGCEIRLG 363 Query: 366 AGGAFQPQGEGVAAGAFFAPTLLLARDTGAGSPVHEVEAFGPVSTLMPYDDLDEALALAA 425 Q + AAGAFF PTLL VH EAFGPV+TLMP + AL LA Sbjct: 364 G------QADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQRHALQLAC 417 Query: 426 RGRGSLVASLVTRSPAVAARAIPVAAAWHGRLLVLDREAATESTGHGSPLPQLKHGGPGR 485 G GSL +LVT P +A + I AA HGR+ +L+ E+A ESTGHGSPLPQL HGGPGR Sbjct: 418 AGGGSLAGTLVTADPQIARQFIADAARTHGRIQILNEESAKESTGHGSPLPQLVHGGPGR 477 Query: 486 AGGGEELGGARAVKHYLQRTAVQ 508 AGGGEELGG RAVKHY+QRTAVQ Sbjct: 478 AGGGEELGGLRAVKHYMQRTAVQ 500 >SMb21635_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 487 Score = 499 bits (1284), Expect = e-140, Method: Compositional matrix adjust. Identities = 269/485 (55%), Positives = 328/485 (67%) Query: 18 GESPAQALHSAVNGHTVASTHAESIDFGEALDHARRQGLPGLMALDFQQRAAILKALGKY 77 G L A G VA + IDF AL + R +G P L + F +RA +LKAL + Sbjct: 3 GSKDGVTLCDAATGAPVALVDSSGIDFAAALAYGREKGGPALRRMSFHERAMMLKALAQA 62 Query: 78 LMEHKETLYAVSAHTGATRNDSWIDIEGGSGTLFAYASIGTNEFPSSNLVHEGPALALGK 137 LME KE YA+S TGATR DSWIDIEGG GTLF+YAS G E P+S+++ +G AL + Sbjct: 63 LMERKEEFYALSTATGATRADSWIDIEGGIGTLFSYASKGRRELPNSHVLLDGDVEALSR 122 Query: 138 QGRFSGTHILVPRGGVAVHINAFNFPIWGMLEKFAPSFLAGMPCIVKPATATSYLTEAAV 197 G FS HIL P G+AVHINAFNFP WGMLEK AP+ LAGMP IVKPA+ T+YL E V Sbjct: 123 DGTFSAQHILTPLQGIAVHINAFNFPCWGMLEKLAPTLLAGMPAIVKPASQTAYLAELVV 182 Query: 198 RLIQQSGLLPAGSLQLVIGATGDLLERLQAQDVVTFTGSADTAAKLRAHPNLIANAIPFN 257 R I +GLLP G+LQLV G+ GDLL+R+ QDVVTFTGSA T KL+ HP ++ N++ F Sbjct: 183 RRIVDTGLLPEGALQLVCGSPGDLLDRVGDQDVVTFTGSATTGRKLKTHPAIVGNSVRFT 242 Query: 258 AEADSLNCAILGPDVTADDEEFELFVKEVAREMSTKAGQKCTAIRRAIVPRQHVDAVAER 317 EADSLN A+LG D EEF LFV+EVAREM++KAGQKCTAIRR I PR H DA+ Sbjct: 243 MEADSLNAAVLGLDAAPGAEEFGLFVREVAREMTSKAGQKCTAIRRVIAPRAHCDALITA 302 Query: 318 LAARLSKIVVGDPALESVRMGPLASKAQQRDVEERVTLLKQGAEVILGAGGAFQPQGEGV 377 L RL+K+ +GDPA E+VRMGPLAS+ Q+ +V R+ L AE++ G Q Sbjct: 303 LGERLAKVPLGDPADENVRMGPLASRDQREEVRARILDLTTDAEIVAGDPARPQLVSGDA 362 Query: 378 AAGAFFAPTLLLARDTGAGSPVHEVEAFGPVSTLMPYDDLDEALALAARGRGSLVASLVT 437 AGAF P LL A VH+VEAFGPVST+MPYD +EA+ L RGRGSLV S+ T Sbjct: 363 EAGAFLNPVLLYCDSPDAARSVHDVEAFGPVSTVMPYDTAEEAVDLVRRGRGSLVTSVFT 422 Query: 438 RSPAVAARAIPVAAAWHGRLLVLDREAATESTGHGSPLPQLKHGGPGRAGGGEELGGARA 497 P +A + A +HGR+++ +R +A STGHGSPLP L HGGPGRAGGGEELGG R Sbjct: 423 NDPDIARELVIGMAPFHGRVMIGNRLSAKSSTGHGSPLPGLVHGGPGRAGGGEELGGMRG 482 Query: 498 VKHYL 502 V+HY+ Sbjct: 483 VRHYM 487 >DR2381_1 [C] COG1012 NAD-dependent aldehyde dehydrogenases Dra Deinococcus radiodurans Length = 473 Score = 477 bits (1228), Expect = e-134, Method: Compositional matrix adjust. Identities = 257/463 (55%), Positives = 310/463 (66%), Gaps = 2/463 (0%) Query: 10 SFIAGRWFGESPAQALHSAVNGHTVASTHAESIDFGEALDHARRQGLPGLMALDFQQRAA 69 S++ G+W Q L AV G VA +E +DF +AL + R G GL L F RA Sbjct: 13 SYVYGQWHANKDGQTLLDAVYGRPVAVISSEGVDFAQALAYGREAG-AGLRKLTFHTRAR 71 Query: 70 ILKALGKYLMEHKETLYAVSAHTGATRNDSWIDIEGGSGTLFAYASIGTNEFPSSNLVHE 129 +LKALG YLME KE YA++ TGATR D W+DIEGG GTLF+Y+S+ E P + + Sbjct: 72 MLKALGNYLMERKEDYYALNLLTGATRRDGWVDIEGGIGTLFSYSSMARRELPDERFLPD 131 Query: 130 GPALALGKQGRFSGTHILVPRGGVAVHINAFNFPIWGMLEKFAPSFLAGMPCIVKPATAT 189 G LGK G F H+LVPR GVAV INA+NFP+WGMLEK AP+F+AGMP +VKPA T Sbjct: 132 GKVEVLGKGGTFMARHLLVPREGVAVQINAYNFPVWGMLEKLAPAFIAGMPSLVKPAPQT 191 Query: 190 SYLTEAAVRLIQQSGLLPAGSLQLVIGATGDLLERLQAQDVVTFTGSADTAAKLRAHPNL 249 +YLTE VR I SG+LP GSLQLV G GDLL+ L QD+V FTGSA TA KL+ HPN+ Sbjct: 192 AYLTERVVRDIIASGILPEGSLQLVTGDPGDLLDHLLEQDMVAFTGSAATANKLKVHPNI 251 Query: 250 IANAIPFNAEADSLNCAILGPDVTADDEEFELFVKEVAREMSTKAGQKCTAIRRAIVPRQ 309 +A +IPFNAEADSLN A+LG V D EF LFVKEVAREM+ KAGQKCTAIRR +VP Sbjct: 252 VARSIPFNAEADSLNAAVLGVTVRPKDPEFALFVKEVAREMTGKAGQKCTAIRRPLVPCH 311 Query: 310 HVDAVAERLAARLSKIVVGDPALESVRMGPLASKAQQRDVEERVTLLKQGAEVILGAGGA 369 VD V E L A L+K+ VGDPA + VRMG L S Q+ V E + L Q AEV++G G Sbjct: 312 LVDPVVEALRAELAKVTVGDPARDDVRMGALVSVEQRERVRETLEKLGQDAEVVIGGGAG 371 Query: 370 FQPQGEGVAAGAFFAPTLLLARDTGAGSPVHEVEAFGPVSTLMPYDDLDEALALAARGRG 429 G+ GAF PT+LL R+ HE+EAFGPV+TLMPYD LD+A+ LA GRG Sbjct: 372 ELLGGDR-EKGAFLDPTVLLCRNPLEAKGPHELEAFGPVATLMPYDTLDDAITLAKMGRG 430 Query: 430 SLVASLVTRSPAVAARAIPVAAAWHGRLLVLDREAATESTGHG 472 SL AS+VT + A + A+ HGR+LVL+R A ESTGHG Sbjct: 431 SLAASVVTFNRHEATELVLGIASTHGRVLVLNRADAKESTGHG 473 >DR2381_2 [I] COG2030 Acyl dehydratase Dra Deinococcus radiodurans Length = 227 Score = 263 bits (671), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 133/210 (63%), Positives = 162/210 (77%) Query: 473 SPLPQLKHGGPGRAGGGEELGGARAVKHYLQRTAVQGSPTMLSAVVGEHVRGAQVRDSGI 532 SPLPQL HGGPGRAGGG E+ G VKH++ + AVQ PT L+A+ EH+ GA+VR+ + Sbjct: 1 SPLPQLLHGGPGRAGGGAEMAGLAGVKHHMNKVAVQADPTTLAAITKEHIPGAEVREDVV 60 Query: 533 HPFRHYFEDLQIGDSHTTHRRTVTEADIVNFGCLSGDHFYMHFDDISARQSPFGKRIAHG 592 HPFR F+ +Q GDS THRRTVTEADIVNF L+GDHFY H DDI A++ FGKR+AHG Sbjct: 61 HPFRKTFDQIQPGDSLLTHRRTVTEADIVNFAALTGDHFYAHVDDIGAKEGIFGKRVAHG 120 Query: 593 YFVLSAAAGLFVSPAPGPVLANYGLDTLRFVKPVGIGDTISARLTCKRKIDRNKKDANGQ 652 YF++SAAAG FVS APGPVLANYGL+ LRFV+PVGIGDTI RLTCKRKI ++ + + Sbjct: 121 YFLISAAAGQFVSAAPGPVLANYGLENLRFVEPVGIGDTIRTRLTCKRKIRKDLRPGEER 180 Query: 653 GQGVVAWDVEVSNQDGELVASYDILTLVAK 682 GVV W E++NQ +LVA+YDILTLV + Sbjct: 181 PTGVVEWHAEITNQHEQLVATYDILTLVER 210 >maoC_2 [I] COG2030 Acyl dehydratase Eco Escherichia coli K12 Length = 181 Score = 227 bits (579), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 110/175 (62%), Positives = 132/175 (75%) Query: 509 GSPTMLSAVVGEHVRGAQVRDSGIHPFRHYFEDLQIGDSHTTHRRTVTEADIVNFGCLSG 568 GSPTML+A+ + VRGA+V + IHPFR YFE+LQ GDS T RRT+TEADIVNF CLSG Sbjct: 1 GSPTMLAAISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSG 60 Query: 569 DHFYMHFDDISARQSPFGKRIAHGYFVLSAAAGLFVSPAPGPVLANYGLDTLRFVKPVGI 628 DHFY H D I+A +S FG+R+ HGYFVLSAAAGLFV GPV+ANYGL++LRF++PV Sbjct: 61 DHFYAHMDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKP 120 Query: 629 GDTISARLTCKRKIDRNKKDANGQGQGVVAWDVEVSNQDGELVASYDILTLVAKK 683 GDTI RLTCKRK + ++ A + GVV W VEV NQ VA Y ILTLVA++ Sbjct: 121 GDTIQVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQ 175