BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3960.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1982 [L] COG0863 DNA modification methylase Rso Ralstonia sol... 388 e-108 STM3386 [L] COG0863 DNA modification methylase Sty Salmonella ty... 135 9e-32 HP1367 [L] COG0863 DNA modification methylase Hpy Helicobacter p... 132 1e-30 yhdJ [L] COG0863 DNA modification methylase Eco Escherichia coli... 129 9e-30 ZyhdJ [L] COG0863 DNA modification methylase EcZ Escherichia col... 128 1e-29 >RSc1982 [L] COG0863 DNA modification methylase Rso Ralstonia solanacearum Length = 270 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 178/260 (68%), Positives = 217/260 (83%), Gaps = 3/260 (1%) Query: 14 LDRVYCEDALDAGGGLARIPDGSVDLLIADPPYGLGKDYGNDSDKLDTAAYLAWTEQWVD 73 +D ++ ED + G+ R+ DGSVDL+IADPPYGLGKDYGNDSDKL AYLAW+E+W++ Sbjct: 6 IDGIFNEDCI---AGVGRLADGSVDLVIADPPYGLGKDYGNDSDKLSGEAYLAWSERWIE 62 Query: 74 AVLPKLKPNGSLYIFLTWRNSPEIFVMLKQRMTMINEIIWDRRVPSMGGSVRRYSSVHDT 133 AVLPKL NGSLY+F TW+ +PE+FVMLK+R++MINEIIWDRRVPSMGGS R++SSVHD Sbjct: 63 AVLPKLARNGSLYLFCTWQYAPELFVMLKRRLSMINEIIWDRRVPSMGGSTRKFSSVHDN 122 Query: 134 IGFFARAKDYFFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYNPKDVWSVSRLHREHK 193 IGFFA ++DY+FD+DA+RIPYDA+TKKARSR F G KWLE+GYNPKDVWSVSRLHR+ Sbjct: 123 IGFFAASRDYYFDVDAVRIPYDAETKKARSRKRFEGKKWLEVGYNPKDVWSVSRLHRQDP 182 Query: 194 ERADHPTQKPLEVVERMVKASCPPGGVVLDPFMGSGTTAVAARRCGRHFTGFELNPDYCE 253 ERA+HPTQKPLE+VERMV ASCPPGG+VLDPF+GSGTTA A R GR F GFE+N +YC Sbjct: 183 ERAEHPTQKPLELVERMVLASCPPGGLVLDPFLGSGTTAAACARLGRRFAGFEINAEYCR 242 Query: 254 LIRQRLDAIDAPAPASQDDE 273 + R+R+ A+ P S D + Sbjct: 243 VARERVAAVTPLGPQSTDSQ 262 >STM3386 [L] COG0863 DNA modification methylase Sty Salmonella typhimurium LT2 Length = 294 Score = 135 bits (341), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 84/242 (34%), Positives = 127/242 (52%), Gaps = 12/242 (4%) Query: 24 DAGGGLARIPDGSVDLLIADPPYGLGKDYGNDSDKLDTAAYLAWTEQWVDAVLPKLKPNG 83 DA L ++P S+DL+ ADPPY +GKD+ + D A++LAW + +D LK +G Sbjct: 21 DALTELKKLPSESIDLIFADPPYNIGKDFDGMVESWDEASFLAWLYECIDECHRVLKKHG 80 Query: 84 SLYIFLTWRNSPEIFVMLKQRMTMINEIIWDRRVPSMGGSVRRY-SSVHDTIGFFARA-K 141 ++YI + N P I + + T+ + I+W S G ++Y S+++ I + K Sbjct: 81 TMYIMNSTENMPYIDLKCRTLFTIKSRIVWS--YDSSGVQAKKYFGSMYEPILMMVKNPK 138 Query: 142 DYFFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYN----PKDVWSVSRLHREHKERAD 197 Y F+ DAI + +T R++ K YN P +VWS R+ E + Sbjct: 139 SYTFNRDAILV----ETTTGAKRALIDYRKNPPQPYNQKKVPGNVWSFPRVRYLMDEYEN 194 Query: 198 HPTQKPLEVVERMVKASCPPGGVVLDPFMGSGTTAVAARRCGRHFTGFELNPDYCELIRQ 257 HPTQKP +++R++ AS P VLDPF GS TT A GR F G ELN +Y ++ + Sbjct: 195 HPTQKPSALLKRIILASSNPSDTVLDPFAGSFTTGAVAAASGRKFIGIELNNEYVKMGLR 254 Query: 258 RL 259 RL Sbjct: 255 RL 256 >HP1367 [L] COG0863 DNA modification methylase Hpy Helicobacter pylori 26695 Length = 260 Score = 132 bits (331), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 89/253 (35%), Positives = 134/253 (52%), Gaps = 24/253 (9%) Query: 14 LDRVYCEDALDAGGGLARIPDGSVDLLIADPPYGLGKDYGNDSDKLDTAAYLAWTEQWVD 73 L+++Y ED L ++ D SVDL I DPPY L K DS K D +L ++ W+D Sbjct: 3 LNKIYIEDVF---TFLDKLEDKSVDLAIIDPPYNL-KIASWDSFKND-EEFLTFSYAWID 57 Query: 74 AVLPKLKPNGSLYIFLTWRNSPEIFVMLK-QRMTMINEIIWDRRVPSMGGSVRRYSSVHD 132 +LPKLK GS YIF T N L +++ +N I W ++ + +RY+ + Sbjct: 58 KMLPKLKDTGSFYIFNTPFNCALFLAYLHHKKVHFLNFITWVKK-DGFANAKKRYNHAQE 116 Query: 133 TIGFFA-RAKDYFFDLDAIRIPYDA--QTKKARSRSIFVGAK-WLEMGYNPK-----DVW 183 +I F++ K+Y F+ D IRI Y++ + K A+S+ I K W NPK DVW Sbjct: 117 SILFYSMHKKNYTFNADEIRIAYESAERIKHAQSKGILKNNKRWFP---NPKGKLCLDVW 173 Query: 184 SVSRLHREHKERAD-----HPTQKPLEVVERMVKASCPPGGVVLDPFMGSGTTAVAARRC 238 ++ KE+ HP+ KP ++ERM+KAS ++LD F GSG T++ A+ Sbjct: 174 EITSQRHVEKEKGKILKPKHPSIKPKALIERMIKASSHKNDLILDLFSGSGMTSLVAKSL 233 Query: 239 GRHFTGFELNPDY 251 R+F G E + +Y Sbjct: 234 ERNFIGCESHAEY 246 >yhdJ [L] COG0863 DNA modification methylase Eco Escherichia coli K12 Length = 296 Score = 129 bits (323), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 80/243 (32%), Positives = 124/243 (51%), Gaps = 10/243 (4%) Query: 24 DAGGGLARIPDGSVDLLIADPPYGLGKDYGNDSDKLDTAAYLAWTEQWVDAVLPKLKPNG 83 DA L +IP SVDL+ ADPPY +GK++ + ++ W + + LK G Sbjct: 23 DALAELKKIPAESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQG 82 Query: 84 SLYIFLTWRNSPEIFVMLKQRMTMINEIIWDRRVPSMGGSVRRYSSVHDTIGFFAR-AKD 142 S+YI + N P I + ++ T+ + I+W + + Y S+++ I + AK+ Sbjct: 83 SMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAK-KHYGSMYEPILMMVKDAKN 141 Query: 143 YFFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYN----PKDVWSVSRLHREHKERADH 198 Y F+ DAI + + K R++ K YN P +VW R+ E +H Sbjct: 142 YTFNGDAILV----EAKTGSQRALIDYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENH 197 Query: 199 PTQKPLEVVERMVKASCPPGGVVLDPFMGSGTTAVAARRCGRHFTGFELNPDYCELIRQR 258 PTQKP +++R++ AS PG +VLDPF GS TT A GR F G E+N +Y ++ +R Sbjct: 198 PTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRR 257 Query: 259 LDA 261 LD Sbjct: 258 LDV 260 >ZyhdJ [L] COG0863 DNA modification methylase EcZ Escherichia coli O157:H7 EDL933 Length = 296 Score = 128 bits (322), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 124/243 (51%), Gaps = 10/243 (4%) Query: 24 DAGGGLARIPDGSVDLLIADPPYGLGKDYGNDSDKLDTAAYLAWTEQWVDAVLPKLKPNG 83 DA L ++P SVDL+ ADPPY +GK++ + ++ W + + LK G Sbjct: 23 DALAELKKLPTESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLLEVIAECHRVLKKQG 82 Query: 84 SLYIFLTWRNSPEIFVMLKQRMTMINEIIWDRRVPSMGGSVRRYSSVHDTIGFFAR-AKD 142 S+YI + N P I + ++ T+ + I+W + + Y S+++ I + AK+ Sbjct: 83 SMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAK-KHYGSMYEPILMMVKDAKN 141 Query: 143 YFFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYN----PKDVWSVSRLHREHKERADH 198 Y F+ DAI + + K R++ K YN P +VW R+ E +H Sbjct: 142 YTFNGDAILV----EAKTGSQRALIDYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENH 197 Query: 199 PTQKPLEVVERMVKASCPPGGVVLDPFMGSGTTAVAARRCGRHFTGFELNPDYCELIRQR 258 PTQKP +++R++ AS PG +VLDPF GS TT A GR F G E+N +Y ++ +R Sbjct: 198 PTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRR 257 Query: 259 LDA 261 LD Sbjct: 258 LDV 260