BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3959.p (368 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 421 e-117 NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 272 8e-73 NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 268 1e-71 aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 210 5e-54 DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferas... 173 7e-43 >RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Rso Ralstonia solanacearum Length = 374 Score = 421 bits (1083), Expect = e-117, Method: Compositional matrix adjust. Identities = 220/372 (59%), Positives = 278/372 (74%), Gaps = 5/372 (1%) Query: 1 MNPSKP--ETVDDLVANVIRPVVRGWHSYHVPSAAGLVKLDAMENPYVLPVALREELAQR 58 MN + P ++DDL+ ++R VR +YHVP A+G+VKLDAMENPY LP LR+ L +R Sbjct: 1 MNANAPVQPSLDDLLGRIVRDDVRAMGAYHVPDASGMVKLDAMENPYHLPAMLRDALGKR 60 Query: 59 LAALELNRYPVPSYTQLKAAICECLGVPAGYEVLLGNGSDELITMLSVACAMPGRTIVAP 118 LA + LNRYPVP+ LKA + + VPAG +VLLGNGSDE+I+++++A A PG T++AP Sbjct: 61 LAEVALNRYPVPTADALKAQLKRVMRVPAGADVLLGNGSDEIISLIAIAAAKPGATVLAP 120 Query: 119 EPGFVMYGISAQMAGLDYVGVPLRADLSLDLPAMLAAIETHKPVITWLGYPNNPTGTLYE 178 PGFVMY +SAQ+ GL +VGVPLRADL+LD AMLAA+ H+P + +L YPNNPTG L++ Sbjct: 121 VPGFVMYAMSAQLMGLKFVGVPLRADLTLDREAMLAAMAEHQPAVIYLAYPNNPTGNLFD 180 Query: 179 MADV---LRIIEAAAPYGLVVVDEAYQPFATSTLMPALPRHNNLVVMRTVSKLGLAGVRL 235 AD+ LR LVVVDEAYQPFA + MP LP ++L+VMRTVSKLGLAG+RL Sbjct: 181 AADMDALLRAARGPVCQSLVVVDEAYQPFAQHSWMPRLPEFDHLLVMRTVSKLGLAGIRL 240 Query: 236 GYLSAAPALLRELDKVRPPYNVNVLTEAAVLFVLDHLHVLESQAARLRAARSDLASALAA 295 GY++ P + ELDKVRPPYNVNVLTEA FVLDH+ VL++QAA LRA R+ L AL+A Sbjct: 241 GYVAGHPKWIAELDKVRPPYNVNVLTEATAAFVLDHVDVLDAQAATLRAERTRLIDALSA 300 Query: 296 LDGVQVFPSAANFILIRVPDADKVFAGLLARKVLVKNAGRMHMLLQNCLRITVSSDEENA 355 GV VFPSAANF+L+RVPDA +F LL R+VLVKN +MH LL NCLR+TVS+ EENA Sbjct: 301 QPGVTVFPSAANFLLLRVPDAAGLFERLLKRRVLVKNVSKMHPLLANCLRVTVSNPEENA 360 Query: 356 IFLTALTAALRE 367 FL A A+L++ Sbjct: 361 QFLDAFAASLQD 372 >NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase NmA Neisseria meningitidis Z2491 Length = 365 Score = 272 bits (696), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 147/347 (42%), Positives = 210/347 (60%), Gaps = 8/347 (2%) Query: 13 VANVIRPVVRGWHSYHVPSAA-GLVKLDAMENPYVLPVALREELAQ----RLAALELNRY 67 V + IR ++ +Y + G KLD+ME+P V P A E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 68 PVPSYTQLKAAICECLGVPAGYEVLLGNGSDELITMLSVACAMPGRTIVAPEPGFVMYGI 127 P PS + L+ A+ +P ++ LGNGSDELI +++ A PG ++A EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 128 SAQMAGLDYVGVPLRADLSLDLPAMLAAIETHKPVITWLGYPNNPTGTLYEMADVLRIIE 187 +A + G+DYVGVPL D +L+LPA+L A+ H+P +T++ YPNNPTG + A++ +IE Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 188 AAAPYGLVVVDEAYQPFATSTLMPALPRHNNLVVMRTVSKLGLAGVRLGYLSAAPALLRE 247 A+ G+VVVDEAY F + +P NL+VMRTVSK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGSIPNLIVMRTVSKIGFAGLRIGYAAGCPEVIGE 240 Query: 248 LDKVRPPYNVNVLTEAAVLFVLDHLHVLESQAARLRAARSDLASALAALDGVQVFPSAAN 307 L K+ PPYN+N L+ L H ++ + L+ R + + L + + FPS AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLKNERERMFAELGKICRLNTFPSQAN 300 Query: 308 FILIRVPDADKVFAGLLARKVLVKNAGRMHMLLQNCLRITVSSDEEN 354 FI IRVPDAD +F L ++LVK H LL++CLRITV S +N Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQN 347 >NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Nme Neisseria meningitidis MC58 Length = 365 Score = 268 bits (686), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 145/347 (41%), Positives = 210/347 (60%), Gaps = 8/347 (2%) Query: 13 VANVIRPVVRGWHSYHVPSAA-GLVKLDAMENPYVLPVALREELAQ----RLAALELNRY 67 V + IR ++ +Y + G KLD+ME+P V P A E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 68 PVPSYTQLKAAICECLGVPAGYEVLLGNGSDELITMLSVACAMPGRTIVAPEPGFVMYGI 127 P PS + L+ A+ +P ++ LGNGSDELI +++ A PG ++A EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 128 SAQMAGLDYVGVPLRADLSLDLPAMLAAIETHKPVITWLGYPNNPTGTLYEMADVLRIIE 187 +A + G+DYVGVPL D +L+LPA+L A+ H+P +T++ YPNNPTG + A++ +IE Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 188 AAAPYGLVVVDEAYQPFATSTLMPALPRHNNLVVMRTVSKLGLAGVRLGYLSAAPALLRE 247 A+ G+VVVDEAY F + +P R NL+V+RT+SK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGRIPNLIVLRTLSKIGFAGLRIGYAAGCPEVIGE 240 Query: 248 LDKVRPPYNVNVLTEAAVLFVLDHLHVLESQAARLRAARSDLASALAALDGVQVFPSAAN 307 L K+ PPYN+N L+ L H ++ + L+ R + + L + + F S AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALRHYGIISANIDSLKNERERMFAELGKICRLNTFSSQAN 300 Query: 308 FILIRVPDADKVFAGLLARKVLVKNAGRMHMLLQNCLRITVSSDEEN 354 FI IRVPDAD +F L ++LVK H LL++CLRITV S +N Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQN 347 >aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Aae Aquifex aeolicus Length = 354 Score = 210 bits (534), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 121/350 (34%), Positives = 186/350 (53%), Gaps = 7/350 (2%) Query: 21 VRGWHSYHVPSAAGLVKLDAMENPYVLPVALREELAQRLAALELNRYPVPSYTQLKAAIC 80 ++ +Y V+L + E PY P +++ + L + LN+YP P +LKA + Sbjct: 6 IKELEAYKTEVTPASVRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLA 65 Query: 81 ECLGVPAGYEVLLGNGSDELITMLSVACAMPGRTIVAPEPGFVMYGISAQMAGLDYVGVP 140 + GV ++LGNGSDELI LS+A + P P F MY ISA++ G V V Sbjct: 66 DFFGVKEE-NLVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQ 124 Query: 141 LRADLSLDLPAMLAAIETHKPVITWLGYPNNPTGTLYEMADVLRIIEAAAPYGLVVVDEA 200 L + +DL + IE KPV+ + YPNNPTG L+ + I V+DEA Sbjct: 125 LDENFDIDLERSIELIEKEKPVLGYFAYPNNPTGNLFSRGKIEEIRNRGV---FCVIDEA 181 Query: 201 YQPFATSTLMPALPRHNNLVVMRTVSKLGLAGVRLGYLSAAPALLRELDKVRPPYNVNVL 260 Y ++ T + + + VV+RT+SK+G+A +R+G L ++ E++KVR P+NV Sbjct: 182 YYHYSGETFLEDALKREDTVVLRTLSKIGMASLRVGILIGKGEIVSEINKVRLPFNVTYP 241 Query: 261 TEA-AVLFVLDHLHVLESQAARLRAARSDLASALAALDGVQVFPSAANFILIRVP-DADK 318 ++ A + + + L + + R + + ++GV+VFPS ANF+L R P A + Sbjct: 242 SQVMAKVLLTEGREFLMEKIQEVVKERERMYDEMKKIEGVEVFPSKANFLLFRTPYPAHE 301 Query: 319 VFAGLLARKVLVKNAGRMHMLLQNCLRITVSSDEENAIFLTALTAALREL 368 V+ LL R VLV+N M LQ CLR++V EEN FL AL +++ L Sbjct: 302 VYQELLKRDVLVRNVSYMEG-LQKCLRVSVGKPEENNKFLEALEESIKSL 350 >DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Dra Deinococcus radiodurans Length = 361 Score = 173 bits (438), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 115/335 (34%), Positives = 173/335 (51%), Gaps = 17/335 (5%) Query: 37 KLDAMENPYVLPVALREELAQRLAALELNRYPVPSYTQLKAAICECLGVPAGYE------ 90 KLD ENPY P L+++ A+R+ A NRYP L+AAI AGYE Sbjct: 34 KLDQNENPYDFPPELKQKAAERMLAHPWNRYPDLHADTLRAAI-------AGYEGWDAAG 86 Query: 91 VLLGNGSDELITMLSVACAMPGRTIVAPEPGFVMYGISAQMAGLDYVGVPLRADLSLDLP 150 V++ GS+ LI +L+ + G+T++ +P F +Y + A M G + V PL D SL + Sbjct: 87 VVITPGSNVLIKILTELGGI-GQTVLTTDPTFSVYTLEAAMLGAELVLTPLNPDFSLPVE 145 Query: 151 AMLAAIETHKPVITWLGYPNNPTGTLYEMADVLRIIEAAAPYGLV-VVDEAYQPFATSTL 209 A L A+ H P + ++ P+ PTG DV R++E A G V V+DEAY +A + Sbjct: 146 ATLQALAAHAPGVFYVTQPHAPTGHSDRPEDVRRVVEVADRLGWVTVIDEAYSQYAGTDY 205 Query: 210 MPALPRHNNLVVMRTVSK-LGLAGVRLGYLSAAPALLRELDKVRPPYNVNVLTEAAVLFV 268 + +++ +RT SK GLAGVR GYL P L L K+ + +N LT+A + Sbjct: 206 RELVRAGKHVLSLRTFSKAWGLAGVRAGYLLTNPELAGHLQKLVSAFTINFLTQAVIETA 265 Query: 269 LDHLHVLESQAARLRAARSDLASALAALDGVQVFPSAANFILIRVPDADKVFAGLLARKV 328 L+H + + A A R + +A+ +FPS NF L++ PDAD + LL + Sbjct: 266 LEHPEYMRERVAEAIAERGRIYAAVQGHPTCTIFPSNTNFFLLKTPDADAAYRHLLEHGI 325 Query: 329 LVKNAGRMHMLLQNCLRITVSSDEENAIFLTALTA 363 + + ++ L CLRI V + EN + A+ A Sbjct: 326 VCRRQDKLRG-LDGCLRIAVGTPAENDALIAAILA 359