BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3938.p (330 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1871 [E] COG2423 Predicted ornithine cyclodeaminase, mu-cryst... 500 e-141 MA3252 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 248 2e-65 AF1665 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crysta... 234 2e-61 MTH1495 [E] COG2423 Predicted ornithine cyclodeaminase, mu-cryst... 232 1e-60 SMb20433 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crys... 191 3e-48 >SMa1871 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Sme Sinorhizobium meliloti Length = 342 Score = 500 bits (1287), Expect = e-141, Method: Compositional matrix adjust. Identities = 227/330 (68%), Positives = 281/330 (85%) Query: 1 MRTLLLKKEEVRKLISMKEVIGTVEEAYRAFSANSVMQPPYTGIHLPEPRGEIDFKLSYY 60 M+TLLLKK+EVR+LI M EVIG VEEAY+AFS++ V QP Y GIH P RGEIDFKL YY Sbjct: 13 MKTLLLKKDEVRRLIGMAEVIGAVEEAYKAFSSDQVEQPDYIGIHHPSLRGEIDFKLGYY 72 Query: 61 KGNEIISMKSSSGAFPDNPKLYGVPSSMGTILLFDARSCALICVMDGSLVTGLRTGAAGA 120 K NEIISMK+ SG F +NP +GVP+S+GTILLFDARSCALIC+MDGSL+TGLRTGA+GA Sbjct: 73 KANEIISMKAHSGGFTNNPAEHGVPNSIGTILLFDARSCALICIMDGSLITGLRTGASGA 132 Query: 121 VSAKVLARKDAKIIGAIGTGQQARMQIRALREVMDIQGIKAWSRTAEKMASFKADIERDV 180 VS K LARK+A+ + +IGTG QARMQIRA+ E+M I+ I AWSRT E ++ +K DI+R+ Sbjct: 133 VSVKALARKNARTVASIGTGNQARMQIRAVNEIMKIEKIHAWSRTPESLSRYKTDIQREF 192 Query: 181 GLPVVLATSAQDVVASSDILITTTRGTGPVVKAEWVKPGTHIIAIGADQQGKQELDPALF 240 G+PV++A+S ++ V +DILITTTRG G +V+A+WVKPGTHI+AIG DQ+GKQELDP +F Sbjct: 193 GIPVIVASSKKEAVEQADILITTTRGKGSLVEADWVKPGTHIVAIGTDQRGKQELDPEIF 252 Query: 241 KHAKIVHDSTAQCCEKGESWHPLTQQIITMNDIHGELGEILLGKKPGRENDEEITIFDST 300 ++AK+V DS AQC EKGE+WHPL + IIT +DIHGE+GE+LLG+KPGRE+D+EITIFDST Sbjct: 253 RNAKVVVDSVAQCTEKGETWHPLNKNIITKDDIHGEIGEVLLGRKPGRESDDEITIFDST 312 Query: 301 GMAIQDNTTATKIYQNAVAQKIGEFFEFIE 330 GMAIQDNTTA+KIYQNA+A +G FF+F E Sbjct: 313 GMAIQDNTTASKIYQNAIANNVGTFFQFFE 342 >MA3252 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Mac Methanosarcina acetivorans str.C2A Length = 326 Score = 248 bits (632), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 135/323 (41%), Positives = 194/323 (60%), Gaps = 3/323 (0%) Query: 1 MRTLLLKKEEVRKLISMKEVIGTVEEAYRAFSANSVMQPPYTGIHLPEPRGEIDFKLSYY 60 M L L +EEV+ ++ M + VE A+R V PP + ++ G++ +Y Sbjct: 1 MEVLWLAQEEVKSVVDMHSDMQVVESAFRQHGLGKVQMPPKSYLYYTVYNGDLRTMPAYL 60 Query: 61 KGNEIISMKSSSGAFPDNPKLYGVPSSMGTILLFDARSCALICVMDGSLVTGLRTGAAGA 120 + +I +K + P NP + +P+ M I+L + A + +MDG+ +T +RTGAAG Sbjct: 61 EEEDITGVKIVN-VHPGNP-MRNLPTVMALIILISPETGAPVAIMDGTYLTDIRTGAAGG 118 Query: 121 VSAKVLARKDAKIIGAIGTGQQARMQIRALREVMDIQGIKAWSRTAEKMASFKADIERDV 180 V+AK LARKD+K+IG +G G QAR Q+ AL EV + + ++ SRT E F ++ V Sbjct: 119 VAAKYLARKDSKVIGLVGAGNQARTQLEALCEVFEPETVRITSRTKESCDQFIKEMSDFV 178 Query: 181 GLPVVLATSAQDVVASSDILITTTRGTGPVVKAEWVKPGTHIIAIGADQQGKQELDPALF 240 ++ S + V DIL+TTT P+VKA WVK GTHI AIGAD GK+ELDP L Sbjct: 179 PCEILYEESVEKV-CDCDILVTTTPTRKPIVKASWVKEGTHINAIGADAVGKEELDPELL 237 Query: 241 KHAKIVHDSTAQCCEKGESWHPLTQQIITMNDIHGELGEILLGKKPGRENDEEITIFDST 300 +KI+ D Q GE PL++ I+ NDIH +LGE+++G KPGR ++EEITIFDST Sbjct: 238 LRSKIIVDDMVQALHSGEVNVPLSKHYISENDIHAQLGEVIVGLKPGRTSEEEITIFDST 297 Query: 301 GMAIQDNTTATKIYQNAVAQKIG 323 G+AIQD TA +Y+ AV + +G Sbjct: 298 GLAIQDVATAHMVYERAVREGLG 320 >AF1665 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Afu Archaeoglobus fulgidus Length = 322 Score = 234 bits (597), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 137/332 (41%), Positives = 194/332 (58%), Gaps = 15/332 (4%) Query: 1 MRTLLLKKEEVRKLISMKEVIGTVEEAYRAFSANSVMQPPYTGIHLPEPRGEIDFKLSYY 60 M TL+L +EEV LISM E + VEEA+R ++ PP ++L +G++ ++ Sbjct: 1 METLILTQEEVESLISMDEAMNAVEEAFRLYALGKAQMPP--KVYLEFEKGDLRAMPAHL 58 Query: 61 KGNEIISMKSSSGAFPDNPKLYGVPSSMGTILLFDARSCALICVMDGSLVTGLRTGAAGA 120 G + +S PD G+P+ M ++L + + VMD + T LRTGAAG Sbjct: 59 MGYAGLKWVNSHPGNPDK----GLPTVMALMILNSPETGFPLAVMDATYTTSLRTGAAGG 114 Query: 121 VSAKVLARKDAKIIGAIGTGQQARMQIRALREVMDIQGIKAWS---RTAEKMASFKADIE 177 ++AK LARK++ + G IG G QA Q+ ALR V DI +KA+ + A+K S+ D Sbjct: 115 IAAKYLARKNSSVFGFIGCGTQAYFQLEALRRVFDIGEVKAYDVREKAAKKFVSYCED-- 172 Query: 178 RDVGLPVVLATSAQDVVASSDILITTTRGTGPVVKAEWVKPGTHIIAIGADQQGKQELDP 237 R + V A A + D+L+TTT PVVKAEWV+ GTHI AIGAD GKQELD Sbjct: 173 RGISASVQPAEEA----SRCDVLVTTTPSRKPVVKAEWVEEGTHINAIGADGPGKQELDV 228 Query: 238 ALFKHAKIVHDSTAQCCEKGESWHPLTQQIITMNDIHGELGEILLGKKPGRENDEEITIF 297 + K AKIV D Q GE +++ +I + D+H +GE++ G K GRE+DEEITIF Sbjct: 229 EILKKAKIVVDDLEQAKHGGEINVAVSKGVIGVEDVHATIGEVIAGLKDGRESDEEITIF 288 Query: 298 DSTGMAIQDNTTATKIYQNAVAQKIGEFFEFI 329 DSTG+AIQD A +Y+NA+++ +G +F Sbjct: 289 DSTGLAIQDVAVAKVVYENALSKNVGSKIKFF 320 >MTH1495 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Mth Methanothermobacter thermautotrophicus Length = 339 Score = 232 bits (591), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 122/322 (37%), Positives = 189/322 (58%), Gaps = 1/322 (0%) Query: 2 RTLLLKKEEVRKLISMKEVIGTVEEAYRAFSANSVMQPPYTGIHLPEPRGEIDFKLSYYK 61 +T++L + +V L++M + + VE A+ + V PP + G++ SY + Sbjct: 12 KTVVLTRSDVEGLLNMDDCLKAVEGAFVQEALGRVQMPPKMYLFFRRYNGDLRVMPSYLE 71 Query: 62 GNEIISMKSSSGAFPDNPKLYGVPSSMGTILLFDARSCALICVMDGSLVTGLRTGAAGAV 121 E+ +K + P NP + +P+ M I L D + I +MDG+ +T +RTGAAG V Sbjct: 72 ELEMAGVKCVN-VHPSNPDRHSLPTVMAVIELVDPETGFPIALMDGTHITDMRTGAAGGV 130 Query: 122 SAKVLARKDAKIIGAIGTGQQARMQIRALREVMDIQGIKAWSRTAEKMASFKADIERDVG 181 S K LA +DA +G IG G+QA Q+ A+ V D++ + + RT F ++ Sbjct: 131 SVKYLASRDASRLGIIGAGRQAWTQLMAISRVADLEEVSVYCRTPSTREKFALRASKEYE 190 Query: 182 LPVVLATSAQDVVASSDILITTTRGTGPVVKAEWVKPGTHIIAIGADQQGKQELDPALFK 241 +PV AT ++ V DI++T T PVV A+WV PGTHI A+GAD GKQELDP + K Sbjct: 191 VPVRAATDPREAVEGMDIVVTVTPSRSPVVMADWVSPGTHICAMGADAPGKQELDPLILK 250 Query: 242 HAKIVHDSTAQCCEKGESWHPLTQQIITMNDIHGELGEILLGKKPGRENDEEITIFDSTG 301 +A++ +DS Q GE P+T+ I+ ++D+ G LG+++ GK GR + ++T+FDSTG Sbjct: 251 NARVFYDSLEQATHSGEINVPITEGILRVDDLQGSLGDVMTGKIEGRTSPADVTVFDSTG 310 Query: 302 MAIQDNTTATKIYQNAVAQKIG 323 ++IQD TTA IY+ AVA ++G Sbjct: 311 LSIQDITTAWMIYERAVAGEVG 332 >SMb20433 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog Sme Sinorhizobium meliloti Length = 329 Score = 191 bits (484), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 119/328 (36%), Positives = 187/328 (57%), Gaps = 4/328 (1%) Query: 2 RTLLLKKEEVRKLISM-KEVIGTVEEAYRAFSANSVMQPPYTGIHLPEPRGEIDFKLSYY 60 R +L + E+R ++ + +E + VE+A+RA + +V PP + +PE RGE+D K +Y Sbjct: 3 RMKILTEAELRGIVPLDREAVACVEDAFRALATKAVAMPPILRLDIPEHRGEVDVKTAYV 62 Query: 61 KGNEIISMKSSSGAFPDNPKLYGVPSSMGTILLFDARSCAL-ICVMDGSLVTGLRTGAAG 119 G + ++K S G F DNPK+ G+PS+ G ++L +++ + ++D +T +RT AAG Sbjct: 63 PGLDGFAIKISPGFF-DNPKI-GLPSTNGMMVLLSSKTGLVQALLLDNGYLTDVRTAAAG 120 Query: 120 AVSAKVLARKDAKIIGAIGTGQQARMQIRALREVMDIQGIKAWSRTAEKMASFKADIERD 179 AV+A+ L+R+D+ + G G QAR+Q+ AL V I+ + W+R A K + + Sbjct: 121 AVAARRLSREDSSVAAVFGAGMQARLQLEALALVRPIREARIWARDAAKAEAAAIALGGK 180 Query: 180 VGLPVVLATSAQDVVASSDILITTTRGTGPVVKAEWVKPGTHIIAIGADQQGKQELDPAL 239 +G V T + + +DI++TTT PV+KAEW++PG H+ A+G+D + K E+DP Sbjct: 181 LGFAVKAETDPRAAITGADIIVTTTPSETPVLKAEWLEPGQHVTAMGSDAEHKNEIDPHA 240 Query: 240 FKHAKIVHDSTAQCCEKGESWHPLTQQIITMNDIHGELGEILLGKKPGRENDEEITIFDS 299 A V DS Q GE H + +++ ELG+++ G KPGR +EITI D Sbjct: 241 IARATYVADSLKQTRRLGELHHAIAAHLMSAEAEFPELGQVIAGLKPGRTRADEITIADL 300 Query: 300 TGMAIQDNTTATKIYQNAVAQKIGEFFE 327 TG IQD AT + A A G FE Sbjct: 301 TGTGIQDTAIATLAFARANAADAGTTFE 328