BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3937.p (323 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1872 [E] COG1171 Threonine dehydratase Sme Sinorhizobium meli... 529 e-150 Ta0113 [E] COG1171 Threonine dehydratase Tac Thermoplasma acidop... 222 7e-58 TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volca... 216 5e-56 SA1271 [E] COG1171 Threonine dehydratase Sau Staphylococcus aure... 215 9e-56 VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp.... 214 2e-55 >SMa1872 [E] COG1171 Threonine dehydratase Sme Sinorhizobium meliloti Length = 323 Score = 529 bits (1363), Expect = e-150, Method: Compositional matrix adjust. Identities = 265/319 (83%), Positives = 294/319 (92%) Query: 1 MHEYPTLQDIHQARERLLPHIRHTPLLRAEKIEKQLGCELYLKPETLQITGAFKIRGALN 60 M YPT+QDI +ARERL PH+RHTPLLRAEKIEK GC+LYLKPETLQITGAFKIRGALN Sbjct: 1 MRNYPTIQDIREARERLKPHVRHTPLLRAEKIEKAAGCQLYLKPETLQITGAFKIRGALN 60 Query: 61 KSLSLPKEAIANGIIATSSGNHAQGLAYAARMLGVKALLVLPVTTPKIKIANTQALGAEV 120 K+LSL +E IANGIIATSSGNHAQGL+YAA+MLGVK +LVLPVTTPKIKI NT+ALGAEV Sbjct: 61 KALSLSREEIANGIIATSSGNHAQGLSYAAKMLGVKVILVLPVTTPKIKIENTKALGAEV 120 Query: 121 ILFDGDTAARWKRVAEIAEENHYVMVHAFEDPVVMAGQGTIGCEIIDDLPDVDTVIIPIG 180 ILFDGD AARWK+V EIAE N Y ++H FEDPVVMAGQGTIGCEI++DL DVDTVI+P+G Sbjct: 121 ILFDGDNAARWKKVYEIAEGNKYAVIHGFEDPVVMAGQGTIGCEILEDLDDVDTVIVPLG 180 Query: 181 GGGLISGIATALKETRPSIRVVGAEPALTPKYYQSRINKQRTSLPLKNTIADGLRISVPG 240 GGGLISGIATA+KET+PS+RV+GAEPALTPKY+ SR+NK+RTSLPLKNTIADGLRISVPG Sbjct: 181 GGGLISGIATAIKETKPSVRVIGAEPALTPKYFHSRVNKERTSLPLKNTIADGLRISVPG 240 Query: 241 QNPYPIIEKYVDEIVLVEDEHIIEGMRILAKDAKLIAEPAASIGIGALLAGGLSVRPDEK 300 QNPYPIIEKYVDEIVLVEDEHII GMR LAKDAKLIAEPAASIG+GALLAG + V+ DEK Sbjct: 241 QNPYPIIEKYVDEIVLVEDEHIIAGMRALAKDAKLIAEPAASIGVGALLAGIIDVKLDEK 300 Query: 301 VCAVLTGGNWDLFDLADVY 319 VCAVL+GGNWDL DLA +Y Sbjct: 301 VCAVLSGGNWDLRDLAAIY 319 >Ta0113 [E] COG1171 Threonine dehydratase Tac Thermoplasma acidophilum Length = 406 Score = 222 bits (566), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 121/307 (39%), Positives = 185/307 (60%), Gaps = 5/307 (1%) Query: 5 PTLQDIHQARERLLPHIRHTPLLRAEKIEKQLGCELYLKPETLQITGAFKIRGALNKSLS 64 P+ +DI A+ L I TPL+++ + G E+Y K E Q TG+FK RGAL K Sbjct: 7 PSYEDILSAKAYLEGRINRTPLIKSTTFGNEYGSEMYFKLENFQKTGSFKSRGALFKFSK 66 Query: 65 LPKEAIANGIIATSSGNHAQGLAYAARMLGVKALLVLPVTTPKIKIANTQALGAEVIL-- 122 L ++ G++ S+GNHAQG+AYAA++ G+ A +V+P T K+ GAEVIL Sbjct: 67 LSEDDRRRGVLTASAGNHAQGVAYAAKVNGINAKIVMPEYTIPQKVNAVAGYGAEVILHG 126 Query: 123 FDGDTAARWKRVAEIAEENHYVMVHAFEDPVVMAGQGTIGCEIIDDLPDVDTVIIPIGGG 182 FD D A R+ ++A + + V + AF D V++GQGTIG EI++D PD+DT+I+P+GGG Sbjct: 127 FDYDEAHRY--ADDLARKENRVFIEAFNDRWVISGQGTIGLEIMEDRPDIDTIIVPVGGG 184 Query: 183 GLISGIATALKETRPSIRVVGAEPALTPKYYQSRINKQRTSLPLKNTIADGLRISVPGQN 242 GLISGIA A K P +R++G E L+ S + + +I DG+ + PG Sbjct: 185 GLISGIALAAKHHNPHVRIIGIESELSDSMKASLREGKIVAHTSGVSICDGISVKYPGDL 244 Query: 243 PYPIIEKYVDEIVLVEDEHIIEGMRILAKDAKLIAEPAASIGIGALLAGGLSVRPDEKVC 302 + I + YVD+IV V +E + + + L + K++AEP+ ++G+ A++ G + V+ KV Sbjct: 245 TFNIAKDYVDDIVTVTEESVSKAIYRLFERMKIVAEPSGAVGLAAIMEGKVDVK-GRKVA 303 Query: 303 AVLTGGN 309 V++GGN Sbjct: 304 IVVSGGN 310 >TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volcanium Length = 406 Score = 216 bits (551), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 117/307 (38%), Positives = 185/307 (60%), Gaps = 1/307 (0%) Query: 3 EYPTLQDIHQARERLLPHIRHTPLLRAEKIEKQLGCELYLKPETLQITGAFKIRGALNKS 62 E P+ +I +A+ L + TPL+R+ I K+ G ++Y K E Q TG+FK RGA+ + Sbjct: 5 EIPSFDEIIEAQRYLEGKVNRTPLIRSTTIGKEYGADIYFKLENFQKTGSFKSRGAIFRF 64 Query: 63 LSLPKEAIANGIIATSSGNHAQGLAYAARMLGVKALLVLPVTTPKIKIANTQALGAEVIL 122 L ++ +G+I S+GNHAQG+AYAA + G+ A +V+P T K+ + GA VIL Sbjct: 65 SKLSEDEKRHGVITASAGNHAQGVAYAAMINGIDAKIVMPEYTIPQKVNAVISYGAHVIL 124 Query: 123 FDGDTAARWKRVAEIAEENHYVMVHAFEDPVVMAGQGTIGCEIIDDLPDVDTVIIPIGGG 182 D + EIA++ + + AF D V++GQGTIG EI++DLPDVD +++P+GGG Sbjct: 125 KGSDYDEAHRYADEIAKQEGRIFIEAFNDRWVISGQGTIGLEIMEDLPDVDIILVPVGGG 184 Query: 183 GLISGIATALKETRPSIRVVGAEPALTPKYYQSRINKQRTSLPLKNTIADGLRISVPGQN 242 GLISGIA A K ++V+G E L+ S + + +I DG+ + PG Sbjct: 185 GLISGIALAAKHASNKVKVIGIESELSDSMKASLREGKIVAHTSGVSICDGISVKYPGVL 244 Query: 243 PYPIIEKYVDEIVLVEDEHIIEGMRILAKDAKLIAEPAASIGIGALLAGGLSVRPDEKVC 302 + I KYVD+IV V +E++ + + L + K++AEP+ ++G+ A++ G + V+ +KV Sbjct: 245 TFDIARKYVDDIVTVTEEYVSKAIYKLFERNKIVAEPSGAVGLAAIMEGKVDVK-GKKVA 303 Query: 303 AVLTGGN 309 V++GGN Sbjct: 304 IVVSGGN 310 >SA1271 [E] COG1171 Threonine dehydratase Sau Staphylococcus aureus N315 Length = 346 Score = 215 bits (548), Expect = 9e-56, Method: Compositional matrix adjust. Identities = 131/320 (40%), Positives = 198/320 (61%), Gaps = 11/320 (3%) Query: 6 TLQDIHQARERLLPHIRHTPLLRAEKIEKQL-GCELYLKPETLQITGAFKIRGALNKSLS 64 +L DI +A+ + P IR TPL+++ + + + +YLK E +Q TG+FK RGA NK Sbjct: 15 SLGDIEEAKASIKPFIRRTPLIKSMYLSQNITKGNVYLKLENMQFTGSFKFRGASNKINH 74 Query: 65 LPKEAIANGIIATSSGNHAQGLAYAARMLGVKALLVLPVTTPKIKIANTQALGAEVILFD 124 L E A GII S+GNHAQG+A A++LG+ A +V+P T P K T+ GA+VIL Sbjct: 75 LSDEQKAKGIIGASAGNHAQGVALTAKLLGIDATIVMPETAPIAKQNATKGYGAKVILKG 134 Query: 125 GDTAARWKRVAEIAEENHYVMVHAFEDPVVMAGQGTIGCEIIDDLPDVDTVIIPIGGGGL 184 + + E+A+EN +VH ++D VMAGQGTIG EI+DD+ +V+TVI+P+GGGGL Sbjct: 135 KNFNETRLYMEELAKENGMTIVHPYDDKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGL 194 Query: 185 ISGIATALKETRPSIRVVGAEP----ALTPKYYQSRINKQRTSLPLKNTIADGLRISVPG 240 I+GIATALK PSI ++G + + +Y+ + + R +TIADG + VPG Sbjct: 195 IAGIATALKSFNPSIHIIGVQAENVHGMAESFYKRALTEHRED----STIADGCDVKVPG 250 Query: 241 QNPYPIIEKYVDEIVLVEDEHIIEGMRILAKDAKLIAEPAASIGIGALLAGGLSVR--PD 298 + Y +++ VDE +LV +E I M+ L + AK+I E A ++ A+L+G + + Sbjct: 251 EKTYEVVKHLVDEFILVSEEEIEHAMQDLMQRAKIITEGAGALPTAAILSGKIDKKWLEG 310 Query: 299 EKVCAVLTGGNWDLFDLADV 318 + V A+++GGN DL ++ V Sbjct: 311 KNVVALVSGGNVDLTRVSGV 330 >VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp. NRC-1 Length = 495 Score = 214 bits (544), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 125/309 (40%), Positives = 175/309 (56%), Gaps = 4/309 (1%) Query: 6 TLQDIHQARERLLPHIRHTPLLRAEKIEKQLGCELYLKPETLQITGAFKIRGALNKSLSL 65 +L DI ARER+ RHTPL + G ++ K E Q TG+FKIRGA N+ +L Sbjct: 88 SLSDIRDARERVSETARHTPLEYSHTFSDLTGADVRPKLECFQRTGSFKIRGATNRIRTL 147 Query: 66 PKEAIANGIIATSSGNHAQGLAYAARMLGVKALLVLPVTTPKIKIANTQALGAEVILF-- 123 + G++ S+GNHAQG+A AA GV + +V+P + P KI T++ GAEV+L Sbjct: 148 SADQQDAGVVTASAGNHAQGVALAASRSGVDSKVVMPESAPISKIKATKSYGAEVVLHGA 207 Query: 124 DGDTAARWKRVAEIAEENHYVMVHAFEDPVVMAGQGTIGCEIIDDLPDVDTVIIPIGGGG 183 D D A E AE YV HAF+D +MAGQGT+G EI D P VDTV++PIGGGG Sbjct: 208 DYDDAQAHAHELEAAEGRTYV--HAFDDEYIMAGQGTLGLEIAADCPTVDTVVVPIGGGG 265 Query: 184 LISGIATALKETRPSIRVVGAEPALTPKYYQSRINKQRTSLPLKNTIADGLRISVPGQNP 243 LISG+ATALK +RV+G + +S Q ++ +TIADG+ + G Sbjct: 266 LISGVATALKGELDDVRVIGVQAEGASTVARSLDKGQPQAVDHVDTIADGIAVRQVGAQT 325 Query: 244 YPIIEKYVDEIVLVEDEHIIEGMRILAKDAKLIAEPAASIGIGALLAGGLSVRPDEKVCA 303 +P+I+++VDE+V V D+ I + +L + K + E A + + A+L E + Sbjct: 326 FPVIQEHVDEVVTVSDDEIATALVLLLERGKTLVEGAGATALAAVLEDKFEYADGETIVP 385 Query: 304 VLTGGNWDL 312 L GGN DL Sbjct: 386 ALCGGNIDL 394