BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3840.p (495 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0888 [U] COG2831 Hemolysin activation/secretion protein Rso R... 502 e-142 RSp0550 [U] COG2831 Hemolysin activation/secretion protein Rso R... 501 e-141 RSp1075 [U] COG2831 Hemolysin activation/secretion protein Rso R... 382 e-105 YPO2491 [U] COG2831 Hemolysin activation/secretion protein Ype Y... 346 6e-95 YPO0598 [U] COG2831 Hemolysin activation/secretion protein Ype Y... 343 5e-94 >RSc0888 [U] COG2831 Hemolysin activation/secretion protein Rso Ralstonia solanacearum Length = 590 Score = 502 bits (1293), Expect = e-142, Method: Compositional matrix adjust. Identities = 258/500 (51%), Positives = 335/500 (67%), Gaps = 9/500 (1%) Query: 2 LHVPEQLPALAQAAGASALPQDPFRFAQQYLDQYAGQCVGKDGLNLIVKRLTALILSKGY 61 L VP+ LP A+ GASALPQDPF FAQ +LD Y G CVGK G++L+ K ++ ILS+GY Sbjct: 94 LEVPQDLPEAARTKGASALPQDPFAFAQAWLDHYTGACVGKQGVDLLTKGVSQAILSRGY 153 Query: 62 STTRLGIAAQDLSSHRLELTLVPGMIRAIKFSSDAAGTTWKSAFPTGPGQLLNLRDLEQG 121 TTR+ + QDLS+ L LVPGMI I+F+ TWKSAFP+ PG LLNLRDLEQG Sbjct: 154 VTTRVLLPQQDLSTGTLRFVLVPGMIGQIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQG 213 Query: 122 LEQMKRVPTQDVTMEIVPGELPGESDVVITVKRKTPWKLTAALDDSGAKGTGKLQSSVNL 181 LEQMKRV +QDV M++VP ++PG SDVVI+VKR PW + AA+D+SG + TGKLQ +++L Sbjct: 214 LEQMKRVASQDVDMQLVPTDVPGVSDVVISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSL 273 Query: 182 AWDNLFGLNDLFNIGLNTDADRRGQQRGTHGSNIYYSIPYGYWTFSAAASTYAYHQQIAG 241 + DN GL+DLFN+G + D D ++RGTHG N +YS+P+GYWT + +A + Y QQIAG Sbjct: 274 SLDNPLGLSDLFNVGYSQDLDFSNKERGTHGWNGFYSVPWGYWTATVSAYSSTYFQQIAG 333 Query: 242 LFQTFVSSGKSQNLEFTVQRLFYRDQVEKHSVQFKVAKRWNRSYVDDTELEVQRRNTTAA 301 + QTFVSSG SQN + +QR+ R Q + VQF+++KR+ +++VDDTE+ QRRN T A Sbjct: 334 VNQTFVSSGNSQNFDVKLQRVIERSQNDVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVA 393 Query: 302 ELAWLYTRYIGDAQFNLVLANRWGVSWFNGQPDLEPRLAD--APTYRYSLQTIDASLYAP 359 E Y G AQF+ L R GV F Q D LAD PT+ Y + DA+L P Sbjct: 394 EAGLTDRHYFGAAQFDGSLLLRHGVGDFGAQDD---TLADGGGPTWHYRMLVADANLSVP 450 Query: 360 FKLGTQSFNYIGALRGQSTHSTLFLSDQFAIGNRYTVRGFDGEQTLSAERGVYLRNEIEM 419 FK+GTQ Y+ RGQ T+ L+ D IG+RYTVRGFDGE +L +RG Y RNE++ Sbjct: 451 FKVGTQPLRYVTTFRGQFTNDHLYSIDAITIGSRYTVRGFDGEMSLLGDRGFYWRNELQA 510 Query: 420 PLGETRQALYAGLDAGRVFGPGAQLLVGTKMAGAAIGLRG----NAAGVRYDVFAGWALV 475 P+G T +LY GLD G V+GP L GT++AGA IGLRG + + YD+F G + Sbjct: 511 PIGNTGLSLYGGLDYGHVYGPSTVGLAGTQLAGAVIGLRGGWGTSYGSLSYDLFIGTPVY 570 Query: 476 KPAGLKTATPSAGFSISYQY 495 KPA TA + GF + YQY Sbjct: 571 KPAAFNTARITTGFQLVYQY 590 >RSp0550 [U] COG2831 Hemolysin activation/secretion protein Rso Ralstonia solanacearum Length = 590 Score = 501 bits (1290), Expect = e-141, Method: Compositional matrix adjust. Identities = 257/500 (51%), Positives = 333/500 (66%), Gaps = 9/500 (1%) Query: 2 LHVPEQLPALAQAAGASALPQDPFRFAQQYLDQYAGQCVGKDGLNLIVKRLTALILSKGY 61 L VP+ LP A+ GASALPQDPF FAQ +LD Y C+GK G++L+ K ++ ILS+GY Sbjct: 94 LEVPQDLPEAARIKGASALPQDPFAFAQAWLDHYNSTCIGKQGVDLLTKGVSQAILSRGY 153 Query: 62 STTRLGIAAQDLSSHRLELTLVPGMIRAIKFSSDAAGTTWKSAFPTGPGQLLNLRDLEQG 121 TTR+ + QDLS+ L LVPGMI I+F+ TWKSAFP+ PG LLNLRDLEQG Sbjct: 154 VTTRVLLPQQDLSTGTLRFVLVPGMIGQIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQG 213 Query: 122 LEQMKRVPTQDVTMEIVPGELPGESDVVITVKRKTPWKLTAALDDSGAKGTGKLQSSVNL 181 LEQMKRV +QDV M++VP ++PG SDVVI+VKR PW + AA+D+SG + TGKLQ +++L Sbjct: 214 LEQMKRVASQDVDMQLVPTDVPGVSDVVISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSL 273 Query: 182 AWDNLFGLNDLFNIGLNTDADRRGQQRGTHGSNIYYSIPYGYWTFSAAASTYAYHQQIAG 241 + DN GLNDLFN+G + D D ++ GTHG N +YS+P+GYWT + +A + Y QQIAG Sbjct: 274 SLDNPLGLNDLFNVGYSQDLDFSNKEHGTHGWNGFYSVPWGYWTATVSAYSSTYFQQIAG 333 Query: 242 LFQTFVSSGKSQNLEFTVQRLFYRDQVEKHSVQFKVAKRWNRSYVDDTELEVQRRNTTAA 301 + QTFVSSG SQN + +QR+ R Q + VQF+++KR+ +++VDDTE+ QRRN T Sbjct: 334 VNQTFVSSGNSQNFDIKLQRVIERSQNDVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVV 393 Query: 302 ELAWLYTRYIGDAQFNLVLANRWGVSWFNGQPDLEPRLAD--APTYRYSLQTIDASLYAP 359 E Y G AQF+ L R GV Q D LAD PT+ Y + DA+L P Sbjct: 394 ETGLTDRHYFGAAQFDGSLLLRHGVGDLGAQDDT---LADGGGPTWHYRMLVADANLSVP 450 Query: 360 FKLGTQSFNYIGALRGQSTHSTLFLSDQFAIGNRYTVRGFDGEQTLSAERGVYLRNEIEM 419 FK+GTQ Y+ RGQ T+ L+ D IG+RYTVRGFDGE +L +RG Y RNE++ Sbjct: 451 FKVGTQPLRYVTTFRGQFTNDHLYSIDAITIGSRYTVRGFDGEMSLVGDRGFYWRNELQA 510 Query: 420 PLGETRQALYAGLDAGRVFGPGAQLLVGTKMAGAAIGLRGN----AAGVRYDVFAGWALV 475 P+G T +LY GLD G V+GP L GT++AGA IGLRG A YD+FAG + Sbjct: 511 PIGNTGLSLYGGLDYGHVYGPSTVGLAGTQLAGAVIGLRGGWGTRAGSFSYDLFAGTPVY 570 Query: 476 KPAGLKTATPSAGFSISYQY 495 KPA +TA +AGF + YQY Sbjct: 571 KPAAFQTARVTAGFQLIYQY 590 >RSp1075 [U] COG2831 Hemolysin activation/secretion protein Rso Ralstonia solanacearum Length = 578 Score = 382 bits (981), Expect = e-105, Method: Compositional matrix adjust. Identities = 210/470 (44%), Positives = 284/470 (60%), Gaps = 9/470 (1%) Query: 33 DQYAGQCVGKDGLNLIVKRLTALILSKGYSTTRLGIAAQDLSSHRLELTLVPGMIRAIKF 92 D G+C+G G+NL++KR+ I+++GY TTR+ A QDL L LTLVPG IRAI+F Sbjct: 111 DPATGRCLGTAGINLVMKRVQNAIVARGYVTTRVLAAPQDLKQGTLALTLVPGRIRAIRF 170 Query: 93 SSDAA--GTTWKSAFPTGPGQLLNLRDLEQGLEQMKRVPTQDVTMEIVP----GELPGES 146 S D++ T W +A P PG +LNLRD+EQGLE KRVPT D ++I P G PGES Sbjct: 171 SDDSSPRATRW-NALPAAPGDILNLRDIEQGLENFKRVPTADADIQIAPADGPGATPGES 229 Query: 147 DVVITVKRKTPWKLTAALDDSGAKGTGKLQSSVNLAWDNLFGLNDLFNIGLNTD-ADRRG 205 D+VI K+ P++L A DDSG+K TGK Q SV +++D+ + LNDLF N D Sbjct: 230 DLVIAWKQGLPFRLNVAADDSGSKYTGKYQGSVTVSYDHWWTLNDLFYASFNHDLGGGYS 289 Query: 206 QQRGTHGSNIYYSIPYGYWTFSAAASTYAYHQQIAGLFQTFVSSGKSQNLEFTVQRLFYR 265 +GT G ++Y +PY YW S+Y Y+Q + G QT++ SG S+N E + RLFYR Sbjct: 290 GSKGTRGYTVHYEVPYDYWLLGFTTSSYDYYQSVVGANQTYIYSGTSENSEVRLSRLFYR 349 Query: 266 DQVEKHSVQFKVAKRWNRSYVDDTELEVQRRNTTAAELAWLYTRYIGDAQFNLVLANRWG 325 D V K S + R + +++DDTE+EVQRR E+ + +IG A + +A R G Sbjct: 350 DAVRKTSAYVRGWVRSSANFIDDTEVEVQRRRMAGWEIGLNHREFIGAATLDANVAYRKG 409 Query: 326 VSWFNGQPDLEPRLADAPTYRYSLQTIDASLYAPFKLGTQSFNYIGALRGQSTHSTLFLS 385 + P E D T R SL T DA L PF + +Q Y A RGQ + L Sbjct: 410 TGMLSSLPAPEESF-DEGTARPSLITADAQLTVPFAVASQRLRYTTAWRGQWNRTPLVPQ 468 Query: 386 DQFAIGNRYTVRGFDGEQTLSAERGVYLRNEIEMPLGETRQALYAGLDAGRVFGPGAQLL 445 D+F+IG RYTVRGFDGE TL +RG +RN++ LG + Q LY G+D G V G A++L Sbjct: 469 DRFSIGGRYTVRGFDGENTLIGDRGWLVRNDLGWTLGNSGQELYVGVDYGEVGGQSARVL 528 Query: 446 VGTKMAGAAIGLRGNAAGVRYDVFAGWALVKPAGLKTATPSAGFSISYQY 495 +G +AGA +GLRG G+ +DVF G L KP G +TA +AGF++S+ Y Sbjct: 529 IGQHLAGAVLGLRGGYKGLFWDVFIGTPLSKPEGFRTAHTTAGFNVSWSY 578 >YPO2491 [U] COG2831 Hemolysin activation/secretion protein Ype Yersinia pestis Length = 562 Score = 346 bits (888), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 182/468 (38%), Positives = 282/468 (60%), Gaps = 3/468 (0%) Query: 29 QQYLDQYAGQCVGKDGLNLIVKRLTALILSKGYSTTRLGIAAQDLSSHRLELTLVPGMIR 88 Q+ +Q GQC+G G+N ++ +L ++ GY TTR+ QDL+S L L +VPG I Sbjct: 97 QRIANQALGQCLGGQGINQLMSQLQNRLVGHGYVTTRVLAPQQDLNSGTLALQVVPGKIH 156 Query: 89 AIKFSSDA-AGTTWKSAFPTGPGQLLNLRDLEQGLEQMKRVPTQDVTMEIVPGELPGESD 147 + + ++ T SAFP PG LL+LRD+EQGLE ++R+PT +ME++PG PGE+D Sbjct: 157 RVALTPESDRHVTLFSAFPARPGHLLDLRDIEQGLENLQRIPTVQASMELIPGSAPGETD 216 Query: 148 VVITVKRKTPWKLTAALDDSGAKGTGKLQSSVNLAWDNLFGLNDLFNIGLNTDADRRGQQ 207 + ++ K+ W+L A+LDDSG + TG+ Q L DN F L+D F + RG Sbjct: 217 IALSWKQSKMWRLAASLDDSGTRSTGRYQGGATLFLDNPFSLSDQFYVSAGGSIKNRGD- 275 Query: 208 RGTHGSNIYYSIPYGYWTFSAAASTYAYHQQIAGLFQTFVSSGKSQNLEFTVQRLFYRDQ 267 +GT+ +YS+P+GYWT AS+Y YHQ +AGL + G+S+N+ + RL +R+ Sbjct: 276 KGTNNLTGHYSLPFGYWTAGITASSYDYHQTVAGLNSDYNYRGESENVSLQLSRLLHRNA 335 Query: 268 VEKHSVQFKVAKRWNRSYVDDTELEVQRRNTTAAELAWLYTRYIGDAQFNLVLANRWGVS 327 +K ++ + V R +++Y++DTE+EVQRR T+A + + +I A + ++ + G Sbjct: 336 SQKTTLTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQATLDAGVSYQRGTR 395 Query: 328 WFNGQPDLEPRLADAPTYRYSLQTIDASLYAPFKLGTQSFNYIGALRGQSTHSTLFLSDQ 387 WF P E + LQ ++A L PF + Q+F+Y + QS+ + L DQ Sbjct: 396 WFGAVPAQEEYFDEGTALSKILQ-LNAQLDIPFSVMAQNFHYNVQYQRQSSSTPLTPQDQ 454 Query: 388 FAIGNRYTVRGFDGEQTLSAERGVYLRNEIEMPLGETRQALYAGLDAGRVFGPGAQLLVG 447 F+IG R++VRGF+GE+TLSA+RG +RN++ Q +Y GLD G V G G+ L+G Sbjct: 455 FSIGGRWSVRGFNGERTLSADRGWTVRNDLGWYTPIQGQEIYVGLDYGEVGGRGSAYLLG 514 Query: 448 TKMAGAAIGLRGNAAGVRYDVFAGWALVKPAGLKTATPSAGFSISYQY 495 +AGAA+G+RGN RYD+FAG L +P G ++ + GF++++QY Sbjct: 515 NHLAGAAVGIRGNVLNTRYDLFAGKPLSEPDGFQSDAVTVGFNLNWQY 562 >YPO0598 [U] COG2831 Hemolysin activation/secretion protein Ype Yersinia pestis Length = 562 Score = 343 bits (880), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 188/484 (38%), Positives = 289/484 (59%), Gaps = 5/484 (1%) Query: 13 QAAGASALPQDPFRFAQQYLDQYAGQCVGKDGLNLIVKRLTALILSKGYSTTRLGIAAQD 72 + +GA LP+ + Q+ DQ GQC+G G+NL++ ++ ++ GY TTR+ QD Sbjct: 83 KISGAEPLPR--WLPLQRIADQAQGQCLGAKGINLLMSQMQNRLVDHGYVTTRVLAPQQD 140 Query: 73 LSSHRLELTLVPGMIRAIKFSSDAAG-TTWKSAFPTGPGQLLNLRDLEQGLEQMKRVPTQ 131 L+S L L +VPG IR ++ + D+ T SAFP G LL+LRD+EQGLE ++RVPT Sbjct: 141 LNSGTLALNVVPGKIRGVELTPDSNRYVTLFSAFPARAGTLLDLRDIEQGLENLQRVPTV 200 Query: 132 DVTMEIVPGELPGESDVVITVKRKTPWKLTAALDDSGAKGTGKLQSSVNLAWDNLFGLND 191 M ++PG PGE+D+++ +++ W+L A+LDDSG + TG+ Q L DN L+D Sbjct: 201 QANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRSTGRYQGGATLFLDNPLSLSD 260 Query: 192 LFNIGLNTDADRRGQQRGTHGSNIYYSIPYGYWTFSAAASTYAYHQQIAGLFQTFVSSGK 251 LF + RRG +GT+ +YS+P+GYWT AS Y Y+Q +AGL G+ Sbjct: 261 LFYVSAGGALQRRGD-KGTNNLTGHYSLPFGYWTAGMTASRYDYYQAVAGLNGDINYRGE 319 Query: 252 SQNLEFTVQRLFYRDQVEKHSVQFKVAKRWNRSYVDDTELEVQRRNTTAAELAWLYTRYI 311 S+N+ F + RL +R+ +K + + V R +++Y++DTE+EVQRR T+A + + +I Sbjct: 320 SENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFI 379 Query: 312 GDAQFNLVLANRWGVSWFNGQPDLEPRLADAPTYRYSLQTIDASLYAPFKLGTQSFNYIG 371 A + ++ + G WF P E +A L+ ++A L PF + Q+ +Y Sbjct: 380 SQAILDAGISYQRGTRWFGAIPAQEEYFGEATALSKILR-LNAQLDIPFVVMAQNLHYNL 438 Query: 372 ALRGQSTHSTLFLSDQFAIGNRYTVRGFDGEQTLSAERGVYLRNEIEMPLGETRQALYAG 431 + QST++ L DQF+IG R++VRGF+GE+TL A+RG ++RN+I L LY G Sbjct: 439 QYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWVRNDIGWYLPLPGHELYVG 498 Query: 432 LDAGRVFGPGAQLLVGTKMAGAAIGLRGNAAGVRYDVFAGWALVKPAGLKTATPSAGFSI 491 +D G V G L+G +AG+A+G+RGN RYD+FAG L KP G KT + + GF++ Sbjct: 499 VDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNGFKTDSLAVGFNL 558 Query: 492 SYQY 495 ++ Y Sbjct: 559 NWLY 562