BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3828.p (424 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0805 [GEPR] COG0477 Permeases of the major facilitator superf... 364 e-100 YPO1504 [GEPR] COG0477 Permeases of the major facilitator superf... 178 2e-44 SMb21000 [GEPR] COG0477 Permeases of the major facilitator super... 159 9e-39 mlr7399 [GEPR] COG0477 Permeases of the major facilitator superf... 151 4e-36 PA1412 [GEPR] COG0477 Permeases of the major facilitator superfa... 147 3e-35 >RSc0805 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 409 Score = 364 bits (934), Expect = e-100, Method: Compositional matrix adjust. Identities = 223/389 (57%), Positives = 267/389 (68%), Gaps = 8/389 (2%) Query: 23 APHPRHGQAWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGY 82 A H AW+V ++GMVALSVAMGIGRFAFTP+LPMMLH+GS++L G WLAT NYLGY Sbjct: 17 AAHATRTAAWRVAIAGMVALSVAMGIGRFAFTPILPMMLHDGSVTLGQGSWLATLNYLGY 76 Query: 83 FLGAMLCALYRSRRGVALLRAGLVATILLTLGMGVLHQDWAWLWMRLLSGVASAYVFVYT 142 F+GA+ C R L+R GLVAT+LLT GMGVL AWL +R +GV SA VFV+T Sbjct: 77 FVGALACMALRGD-AARLIRIGLVATVLLTAGMGVLQGQPAWLVLRFAAGVVSALVFVFT 135 Query: 143 AGWCLQQLTQLGRPELGGVIFCGPGLGIALTGLLSGPMIAAGWLAAGGWIAFGVIALALS 202 AGWCL +LT+LG LGG+IFCGPGLGIA+ GL++ M+A GW A+ WIAFGV++ LS Sbjct: 136 AGWCLHRLTELGHAALGGIIFCGPGLGIAVPGLVASGMVALGWHASSAWIAFGVLSAVLS 195 Query: 203 VVVWPAFSFDAGAQLKVHEHQDHTSQMQQPETPQHKREVLIQVIAYGIAGFGYIITATFL 262 VWP + + H ++ P +I +AYG+AGFGYI+TATFL Sbjct: 196 AAVWPTV------RPERRPHAAASAPGISGAAPGLGLPTVIITLAYGLAGFGYIVTATFL 249 Query: 263 PVIARRALP-GSAWPDYFWPIFGLSVAVGAFSATRLSVQGDQRLLLIGAYLMQALGVLLS 321 PVIARR LP GS WPD FWPIFG+ VA+GA +TR+S+ D R LL AY MQA+ V S Sbjct: 250 PVIARRVLPAGSIWPDLFWPIFGVGVALGALLSTRISLARDNRTLLAAAYAMQAVAVAAS 309 Query: 322 IFWPNALGFALSCLLLGLPFTAITLFGMREARRLRGEQASSLMALMTAAYGIGQIAGPPL 381 I WP G ALS LLLGLPFTAITLF MREARRL LM LMTA YGIGQIAGPPL Sbjct: 310 IVWPTVGGLALSSLLLGLPFTAITLFAMREARRLWPHAVPRLMGLMTAVYGIGQIAGPPL 369 Query: 382 ATALVHGSGSFTPSLCVAAVALLIGAALY 410 A L +G F SL AA +L++G A++ Sbjct: 370 ANRLFAATGGFDASLAAAAASLVLGMAMF 398 >YPO1504 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 383 Score = 178 bits (452), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 140/383 (36%), Positives = 193/383 (50%), Gaps = 19/383 (4%) Query: 31 AWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFLGAMLCA 90 A +V LSG +AL VAMGIGRFAFTP +P+M+ E +L G +A NYLGY GA A Sbjct: 2 ALRVALSGFLALVVAMGIGRFAFTPQVPLMIAEHQFTLTSAGLVAAFNYLGYLFGA-FDA 60 Query: 91 LYRSRRGVALLRAGLVATILLTLGMGVLHQDWAWLWMRLLSGVASAYVFVYTAGWCLQQL 150 + SR L GL LLTL V+ W +R G AS + V A W ++L Sbjct: 61 MRASRHVERRLWLGLWGAALLTLLSAVVVGPWWHGLVRFAIGWASGWSMVLIAAWTNERL 120 Query: 151 TQLGRPELGGVIFCGPGLGIALTGLLSGPMIAAGWLAAGGWIAFGVIALALSVVVWPAFS 210 GRP L +F GPG GI ++G+L+ + + AA W +GV LAL ++ + + Sbjct: 121 AHFGRPALSAAVFAGPGAGIFISGMLAVAIHSYDLSAAEAWWVYGV--LALVIIASISIN 178 Query: 211 FDAGAQLKVHEHQDHTSQMQQPETPQHKREVLIQVIAYGIAGFGYIITATFLPVIARRAL 270 G +L H+ + TP KR V +Y +AGFGYI+ ATFL +A Sbjct: 179 LPRGGEL----HRPQVVAVPLTLTPALKRLVW----SYSLAGFGYILPATFLSQMASARF 230 Query: 271 PGSAWPDYFWPIFG----LSVAVGAFSATRLSVQGDQRLLLIGAYLMQALGVLLSIFWPN 326 P S + + WP+FG + +A+G TR + RL L +QALGVL + + P Sbjct: 231 PDSLFAQFVWPVFGGAAVIGIALGIL--TRHCLTSQTRLAL--TLWVQALGVLCAEWVPG 286 Query: 327 ALGFALSCLLLGLPFTAITLFGMREARRLRGEQASSLMALMTAAYGIGQIAGPPLATALV 386 G AL LL G F ++ ++ R L E + L+T Y IGQ+ GP L+ Sbjct: 287 VSGLALGALLTGGGFLSVVQLSLQHGRELAPEHTRYMAGLLTTGYAIGQLVGPILSAIST 346 Query: 387 HGSGSFTPSLCVAAVALLIGAAL 409 + P+L VA VAL+I L Sbjct: 347 TLTHRLEPALYVAVVALIIAGGL 369 >SMb21000 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 377 Score = 159 bits (403), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 131/379 (34%), Positives = 198/379 (52%), Gaps = 35/379 (9%) Query: 42 LSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFLGAMLCALYR----SRRG 97 ++VAMG GRF++TP+LP M+ + LS G +A+AN++GY GA+L YR RG Sbjct: 1 MAVAMGFGRFSYTPILPAMMTDTGLSPADAGLVASANFIGYLAGAVLAG-YRWAHGRERG 59 Query: 98 VALLRAGLVATILLTLGMGVLHQDWAWLWMRLLSGVASAYVFVYTAGWCLQQLTQLGRPE 157 V L A LVAT LL MG+ A+ +R L+G+ASA+ ++ +G L Q Sbjct: 60 VGL--AALVATTLLLAAMGLTSSVLAYSIIRFLAGLASAFAMIFISGIVLGQGLAARSEH 117 Query: 158 LGGVIFCGPGLGIALTGL------LSGPMIAAGWLAAGGWIAFGVIALALSVVVWPAFSF 211 + V F G G GIAL+ + L+G +A ++ W ++ALA +V+V Sbjct: 118 VPSVHFGGVGFGIALSSIAVWVAPLAG--VAGLSMSQADWFVGALVALAGTVLV------ 169 Query: 212 DAGAQLKVHEHQDHTSQMQQPETP-QHKREVLIQVIAYGIAGFGYIITATFLPVIARRAL 270 + H + +PE P R ++ + YG GFGY+ITATFL +AR A Sbjct: 170 -----AALLPASRHAANGGRPEVPLVRSRPLMAMTLTYGFFGFGYVITATFLVAMARDAS 224 Query: 271 PGSAWPDYFWPIFGLSVAVGA----FSATRLSVQGDQRLLLIGAYLMQALGVLLSIFWPN 326 G + W I G+S A+ F+ R + G + L L++A+G++L++ P+ Sbjct: 225 GGHSVEFLAWLITGVSAALSVYLWRFAVPRFGLAGVYAIGL----LVEAVGLVLTVSLPS 280 Query: 327 ALGFALSCLLLGLPFTAITLFGMREARRLRGEQASSLMALMTAAYGIGQIAGPPLATALV 386 + L+LG F +T +G++ R+L E +A MTAA+GIGQI GP +A L Sbjct: 281 PYAPLVGGLMLGATFMMVTAYGLQIGRQLAPESPRRALAFMTAAFGIGQIVGPLVAGWLA 340 Query: 387 HGSGSFTPSLCVAAVALLI 405 +GS+ VAAV L+I Sbjct: 341 ERTGSYALPTLVAAVVLMI 359 >mlr7399 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 401 Score = 151 bits (381), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 136/394 (34%), Positives = 202/394 (51%), Gaps = 23/394 (5%) Query: 19 HQSTAPHPRHGQAWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATAN 78 + A A + ++GM+A++VAMGIGRF +TP+LP M+ E LS GW+A+AN Sbjct: 11 YMCAAMRSATSTALRFSVAGMIAMAVAMGIGRFVYTPILPGMMEELHLSPANAGWIASAN 70 Query: 79 YLGYFL-GAMLCALYRSRRGVALLRAGLVATILLTLGMGVLHQDWAWLWMRLLSGVASAY 137 YLGY + + R L+ GL A+ +L MG+ A+L +R L+G+ASA+ Sbjct: 71 YLGYLVGAFAAAGGWAHGRERLLMLGGLGASTILAALMGLTDAMAAFLLIRFLAGLASAF 130 Query: 138 VFVYTAGWCLQQLTQLGRPELGGVIFCGPGLGIALTGLLSGPMIA--AGWLAAGGWIAFG 195 V V+ A + GR +L F G GLGIA++ ++ ++ AGW A GW+ Sbjct: 131 VMVFMASIVFSHINAAGRGDLQAWHFGGVGLGIAISAVMMAVLVTEHAGW--AAGWLWSA 188 Query: 196 VIALALSVVVWPAFSFDAGAQLKVHEHQDHTSQMQQPETPQHKREVLIQVIAYGIAGFGY 255 I+ VVV A L + +++P P+ + I +IAYG+ GFGY Sbjct: 189 AISACGFVVV---------ALLANEGPLANGQAVREPALPKDRSLTKI-IIAYGLFGFGY 238 Query: 256 IITATFLPVIARRALPGSAWPDYFWPIFGLSVAVGAFSATRLSVQGDQRLLLIGAY---- 311 ++TATFL I R+ + W + GL+ F +T L + R+ L AY Sbjct: 239 VVTATFLVAIVRQGGGSRVFEAMVWLVAGLA----GFPSTWLWQKIAGRVGLNAAYALAC 294 Query: 312 LMQALGVLLSIFWPNALGFALSCLLLGLPFTAITLFGMREARRLRGEQASSLMALMTAAY 371 L++ +GV S+ G L LLLG F AIT G++ AR+ + + ALMTA++ Sbjct: 295 LIEVIGVTASVALGGYSGPLLGGLLLGGTFIAITALGLQAARQQAPQAPRRIFALMTASF 354 Query: 372 GIGQIAGPPLATALVHGSGSFTPSLCVAAVALLI 405 G+GQI GP A L SG F + VAA L++ Sbjct: 355 GLGQIIGPIAAGLLAQMSGDFFLASIVAAAMLVV 388 >PA1412 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 397 Score = 147 bits (372), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 126/368 (34%), Positives = 166/368 (45%), Gaps = 25/368 (6%) Query: 46 MGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFLGAMLCALYRSRRGVAL-LRAG 104 MG+GRF+ TP LP ++ EG L L G LA ANYLGY +GA+ R R L L G Sbjct: 24 MGVGRFSLTPQLPHLIREGQLDLTGAGLLAAANYLGYLVGALDALFAREARQARLRLLVG 83 Query: 105 LVATILLTLGMGVLHQDWAWLWMRLLSGVASAYVFVYTAGWCLQQLTQLGRPELGGVIFC 164 L A LTL W +R GVASA+V + + + GR LG ++F Sbjct: 84 LWACFGLTLASVWAEGFWPHALLRFGLGVASAWVLIMVTALSQRLAAESGRARLGALVFA 143 Query: 165 GPGLGIALTGLLSGPMIAAGWLAAGGWIAFGVIALALSVVVWPAFS-----FDAGAQLKV 219 GPG+G+ +TGLL+ A G SV +W F+ + Sbjct: 144 GPGIGVMVTGLLA---------------ALGNALGQDSVFIWKLFADLALVLILMLLPLL 188 Query: 220 HEHQDHTSQMQQPETPQHKREVLIQVIAYGIAGFGYIITATFLPVIARRALPGSAWPDYF 279 + P T + AYG+ G GYII ATFL +A G D F Sbjct: 189 PRPAARGAGHDAPATASENAGLGRLTWAYGLVGLGYIIPATFLSQMAAARFHGQWQADLF 248 Query: 280 WPIFGLSVAVGA--FSATRLSVQGDQRLLLIGAYLMQALGVLLSIFWPNALGFALSCLLL 337 WP FGL+ A G S R G +R L+GA +QALGVL + P G AL +L Sbjct: 249 WPCFGLASATGVVLISLRRQRPDGTRR-WLVGALWLQALGVLACLL-PGIGGLALGVVLT 306 Query: 338 GLPFTAITLFGMREARRLRGEQASSLMALMTAAYGIGQIAGPPLATALVHGSGSFTPSLC 397 GLPF A M+ AR L +T + +GQ+ GP LA H +G P+L Sbjct: 307 GLPFLAGMQLVMQYARELAPHTPQRNAGQLTTGFALGQLLGPLLAALSTHFAGGLQPALA 366 Query: 398 VAAVALLI 405 +A + L+ Sbjct: 367 LAGLGLVF 374