BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.3808.p         (291 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0448_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Rso...   204   3e-52
HI1291_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Hin ...   175   9e-44
ECs3654_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ecs...   173   3e-43
PM0476_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Pmu ...   173   4e-43
yqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Eco Es...   172   8e-43

>RSc0448_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Rso Ralstonia
           solanacearum
          Length = 145

 Score =  204 bits (518), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 102/147 (69%), Positives = 115/147 (78%), Gaps = 5/147 (3%)

Query: 145 QFGELSGLLLDRLDVDIEPVSGNPHPDGSQLRANTDEATVEETLVSHLLKSNCPVTSQPD 204
           + GEL+GL LDRLDV+ +     P      L A+ DE+ VEE LVSHLLKSNC VT QPD
Sbjct: 4   KMGELAGLSLDRLDVETDVYQPTP----GLLHADQDESPVEEVLVSHLLKSNCLVTGQPD 59

Query: 205 WGSVQIHYVGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRHCKPQKLAVYARYTR 264
           WGSVQI YVGAPI+QE LLKY+I FREHNEFHEQCVERIF DI R C+P KLAVYARYTR
Sbjct: 60  WGSVQIRYVGAPINQEGLLKYLISFREHNEFHEQCVERIFMDIQRQCRPVKLAVYARYTR 119

Query: 265 RGGLDINPWRSNFSSAKPPSQLRNARQ 291
           RGGLDINP+R+NF++   P  LRNARQ
Sbjct: 120 RGGLDINPFRTNFNTPW-PDNLRNARQ 145


>HI1291_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Hin Haemophilus
           influenzae
          Length = 144

 Score =  175 bits (444), Expect = 9e-44,   Method: Compositional matrix adjust.
 Identities = 82/147 (55%), Positives = 105/147 (71%), Gaps = 6/147 (4%)

Query: 145 QFGELSGLLLDRLDVDIEPVSGNPHPDGSQLRANTDEATVEETLVSHLLKSNCPVTSQPD 204
           +   L G  +D  D++I     N     + L+    +  VEE LVSHLLKSNC +T+QPD
Sbjct: 4   KIDHLQGDCIDEQDIEITSYEFN----ANWLKDCVSDEIVEEKLVSHLLKSNCLITNQPD 59

Query: 205 WGSVQIHYVGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRHCKPQKLAVYARYTR 264
           WG++ IHYVG  I+QE+LL+Y++ FR+HNEFHEQCVERIF D++ + KP+KL VYARYTR
Sbjct: 60  WGTLHIHYVGKKINQEKLLRYVVSFRQHNEFHEQCVERIFCDLMHYAKPEKLTVYARYTR 119

Query: 265 RGGLDINPWRSNFSSAKPPSQLRNARQ 291
           RGGLDINP+RSNF +   P  LR ARQ
Sbjct: 120 RGGLDINPFRSNFENL--PENLRLARQ 144


>ECs3654_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ecs Escherichia
           coli O157:H7
          Length = 146

 Score =  173 bits (439), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 87/147 (59%), Positives = 103/147 (70%), Gaps = 7/147 (4%)

Query: 146 FGELSGLLLDRLDVDIEPVSGNPHPDGSQLR-ANTDEATVEETLVSHLLKSNCPVTSQPD 204
            G  +G  +D  D+ I+    N       L  A + E  VEETLVSHLLKSNC +T QPD
Sbjct: 6   IGHFNGTCIDDQDITID----NYEFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPD 61

Query: 205 WGSVQIHYVGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRHCKPQKLAVYARYTR 264
           WGS+QI Y G  ID+E+LL+Y++ FR HNEFHEQCVERIF D+LR C+P+KL+VYARYTR
Sbjct: 62  WGSIQIQYRGRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTR 121

Query: 265 RGGLDINPWRSNFSSAKPPSQLRNARQ 291
           RGGLDINPWRSN  S   PS  R  RQ
Sbjct: 122 RGGLDINPWRSN--SDFVPSTTRLVRQ 146


>PM0476_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Pmu Pasteurella
           multocida
          Length = 142

 Score =  173 bits (439), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 84/144 (58%), Positives = 105/144 (72%), Gaps = 6/144 (4%)

Query: 148 ELSGLLLDRLDVDIEPVSGNPHPDGSQLRANTDEATVEETLVSHLLKSNCPVTSQPDWGS 207
           EL+G  +D+ D++I     NP      L   T +  V+E+LVSHLLKSNC +T+QPDWG+
Sbjct: 5   ELAGECIDQQDIEINDYQFNPEI----LTNCTHDQMVKESLVSHLLKSNCLITNQPDWGT 60

Query: 208 VQIHYVGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRHCKPQKLAVYARYTRRGG 267
           +QI Y G  ID+E+LL+YII FR+HNEFHEQCVERIF D+++  KP KL VYARYTRRGG
Sbjct: 61  LQIRYEGKQIDREKLLRYIISFRQHNEFHEQCVERIFCDLMQFAKPDKLTVYARYTRRGG 120

Query: 268 LDINPWRSNFSSAKPPSQLRNARQ 291
           LDINP+RSNF +   P   R ARQ
Sbjct: 121 LDINPFRSNFEAV--PDNQRLARQ 142


>yqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Eco Escherichia
           coli K12
          Length = 145

 Score =  172 bits (436), Expect = 8e-43,   Method: Compositional matrix adjust.
 Identities = 87/147 (59%), Positives = 102/147 (69%), Gaps = 7/147 (4%)

Query: 146 FGELSGLLLDRLDVDIEPVSGNPHPDGSQLR-ANTDEATVEETLVSHLLKSNCPVTSQPD 204
            G  +G  +D  D+ I+    N       L  A   E  VEETLVSHLLKSNC +T QPD
Sbjct: 5   IGHFNGTCIDDQDITID----NYEFTTDYLENATCGEKVVEETLVSHLLKSNCLITHQPD 60

Query: 205 WGSVQIHYVGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRHCKPQKLAVYARYTR 264
           WGS+QI Y G  ID+E+LL+Y++ FR HNEFHEQCVERIF D+LR C+P+KL+VYARYTR
Sbjct: 61  WGSLQIQYRGRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTR 120

Query: 265 RGGLDINPWRSNFSSAKPPSQLRNARQ 291
           RGGLDINPWRSN  S   PS  R  RQ
Sbjct: 121 RGGLDINPWRSN--SDFVPSTTRLVRQ 145