BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3802.p (244 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0458 [H] COG2226 Methylase involved in ubiquinone/menaquinone... 411 e-115 NMA0956 [H] COG2226 Methylase involved in ubiquinone/menaquinone... 356 2e-98 NMB0743 [H] COG2226 Methylase involved in ubiquinone/menaquinone... 356 2e-98 PA5063 [H] COG2226 Methylase involved in ubiquinone/menaquinone ... 335 6e-92 VC0083 [H] COG2226 Methylase involved in ubiquinone/menaquinone ... 327 1e-89 >RSc0458 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis Rso Ralstonia solanacearum Length = 243 Score = 411 bits (1056), Expect = e-115, Method: Compositional matrix adjust. Identities = 189/242 (78%), Positives = 215/242 (88%) Query: 3 NTTHFGYETVKEEEKVRKVAEVFHSVAAKYDVMNDFMSAGLHRIWKAFTIAQAGVRPGFK 62 + THFG++ V E EK KVA VFHSVA+KYDVMND MS G+HR+WK FTIAQA VRPG+K Sbjct: 2 SQTHFGFQQVDEREKAGKVAGVFHSVASKYDVMNDLMSGGMHRLWKMFTIAQAAVRPGYK 61 Query: 63 VLDIAGGTGDLSKVFAKQAGPSGEVWLTDINESMLRVGRDRLLNKGIVTPTMLCDAEKLP 122 VLDIAGGTGDL+K FA+QAGP+GEVWLTDINESMLRVGRDRLL+ G++TPT LCDAE +P Sbjct: 62 VLDIAGGTGDLAKAFARQAGPTGEVWLTDINESMLRVGRDRLLDAGVLTPTCLCDAEHIP 121 Query: 123 FPDNYFDRVSVAFGLRNMTHKDAALAEMRRVLKPGGKLLVLEFSKVWEPLKKPYDVYSFS 182 FP+ YFD V+VAFGLRNMTHKD ALAEMRRV+KPGGK++VLEFSKVW+PL+K YDVYSF Sbjct: 122 FPNAYFDVVTVAFGLRNMTHKDRALAEMRRVVKPGGKVMVLEFSKVWQPLEKAYDVYSFK 181 Query: 183 VLPWLGKKVANDADSYRYLAESIRMHPDQENLKQMMEQAGLERVQYFNLTAGVAALHTGI 242 VLPWLG KVA DA+SYRYLAESIRMHPDQE LKQMMEQAGL+ V+YFNLTAGV ALH G Sbjct: 182 VLPWLGSKVAGDAESYRYLAESIRMHPDQETLKQMMEQAGLDSVEYFNLTAGVVALHVGR 241 Query: 243 KM 244 ++ Sbjct: 242 RL 243 >NMA0956 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis NmA Neisseria meningitidis Z2491 Length = 245 Score = 356 bits (914), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 168/239 (70%), Positives = 196/239 (82%) Query: 5 THFGYETVKEEEKVRKVAEVFHSVAAKYDVMNDFMSAGLHRIWKAFTIAQAGVRPGFKVL 64 THFG+ TV E+EK KVAEVFHSVA YD+MND MSAGLHR+WK FTI A ++ G KVL Sbjct: 6 THFGFSTVNEDEKAGKVAEVFHSVAKNYDIMNDVMSAGLHRVWKHFTINTAHLKKGDKVL 65 Query: 65 DIAGGTGDLSKVFAKQAGPSGEVWLTDINESMLRVGRDRLLNKGIVTPTMLCDAEKLPFP 124 DIAGGTGDLS+ +AK+ G GEVWLTDIN SML VGRDRLLN+G++ P L DAEKLPFP Sbjct: 66 DIAGGTGDLSRGWAKRVGKEGEVWLTDINSSMLTVGRDRLLNEGMILPVSLADAEKLPFP 125 Query: 125 DNYFDRVSVAFGLRNMTHKDAALAEMRRVLKPGGKLLVLEFSKVWEPLKKPYDVYSFSVL 184 DNYF+ VSVAFGLRNMTHKDAAL EM RVLKPGG LLVLEFSK+++PL+ YD YSF +L Sbjct: 126 DNYFNLVSVAFGLRNMTHKDAALKEMYRVLKPGGTLLVLEFSKIYKPLEGAYDFYSFKLL 185 Query: 185 PWLGKKVANDADSYRYLAESIRMHPDQENLKQMMEQAGLERVQYFNLTAGVAALHTGIK 243 P +G+ +A DA+SY+YLAESIRMHPDQE LKQMM AG + V Y N++AG+ ALH G+K Sbjct: 186 PAMGRLIAKDAESYQYLAESIRMHPDQETLKQMMLDAGFDSVDYHNMSAGIVALHKGVK 244 >NMB0743 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis Nme Neisseria meningitidis MC58 Length = 245 Score = 356 bits (914), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 168/239 (70%), Positives = 196/239 (82%) Query: 5 THFGYETVKEEEKVRKVAEVFHSVAAKYDVMNDFMSAGLHRIWKAFTIAQAGVRPGFKVL 64 THFG+ TV E+EK KVAEVFHSVA YD+MND MSAGLHR+WK FTI A ++ G KVL Sbjct: 6 THFGFSTVNEDEKAGKVAEVFHSVAKNYDIMNDVMSAGLHRVWKHFTINTAHLKKGDKVL 65 Query: 65 DIAGGTGDLSKVFAKQAGPSGEVWLTDINESMLRVGRDRLLNKGIVTPTMLCDAEKLPFP 124 DIAGGTGDLS+ +AK+ G GEVWLTDIN SML VGRDRLLN+G++ P L DAEKLPFP Sbjct: 66 DIAGGTGDLSRGWAKRVGKEGEVWLTDINSSMLTVGRDRLLNEGMILPVSLADAEKLPFP 125 Query: 125 DNYFDRVSVAFGLRNMTHKDAALAEMRRVLKPGGKLLVLEFSKVWEPLKKPYDVYSFSVL 184 DNYF+ VSVAFGLRNMTHKDAAL EM RVLKPGG LLVLEFSK+++PL+ YD YSF +L Sbjct: 126 DNYFNLVSVAFGLRNMTHKDAALKEMYRVLKPGGTLLVLEFSKIYKPLEGAYDFYSFKLL 185 Query: 185 PWLGKKVANDADSYRYLAESIRMHPDQENLKQMMEQAGLERVQYFNLTAGVAALHTGIK 243 P +G+ +A DA+SY+YLAESIRMHPDQE LKQMM AG + V Y N++AG+ ALH G+K Sbjct: 186 PVMGRLIAKDAESYQYLAESIRMHPDQETLKQMMLDAGFDSVDYHNMSAGIVALHKGVK 244 >PA5063 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis Pae Pseudomonas aeruginosa Length = 256 Score = 335 bits (859), Expect = 6e-92, Method: Compositional matrix adjust. Identities = 161/243 (66%), Positives = 192/243 (79%), Gaps = 3/243 (1%) Query: 4 TTHFGYETVKEEEKVRKVAEVFHSVAAKYDVMNDFMSAGLHRIWKAFTIAQAGVRPGFKV 63 TTHFGY+ V E +K +KVAEVFHSVAAKYD+MND MS G+HR+WK FTI +GVR G +V Sbjct: 13 TTHFGYQNVPESQKAKKVAEVFHSVAAKYDLMNDLMSGGIHRLWKRFTIELSGVRSGNRV 72 Query: 64 LDIAGGTGDLSKVFAKQAGPSGEVWLTDINESMLRVGRDRLLNKGIVTPTML--CDAEKL 121 LDIAGGTGDL++ F++ GP+GEV L DIN SML+VGRD+LL+KG+ DAEKL Sbjct: 73 LDIAGGTGDLTRQFSRLVGPTGEVVLADINASMLKVGRDKLLDKGVSGNVSFVQADAEKL 132 Query: 122 PFPDNYFDRVSVAFGLRNMTHKDAALAEMRRVLKPGGKLLVLEFSKVWEP-LKKPYDVYS 180 PFPDN+FD V++AFGLRN+THKD A+ M RVLKPGG+LLVLEFSK L K YD YS Sbjct: 133 PFPDNHFDCVTIAFGLRNVTHKDEAIRSMLRVLKPGGRLLVLEFSKPSSNLLSKAYDAYS 192 Query: 181 FSVLPWLGKKVANDADSYRYLAESIRMHPDQENLKQMMEQAGLERVQYFNLTAGVAALHT 240 FS+LP +GK V ND++SYRYLAESIRMHPDQE LK MM +AG +RV Y N+T G+ ALH Sbjct: 193 FSLLPLMGKLVTNDSESYRYLAESIRMHPDQETLKAMMVEAGFDRVTYHNMTGGIVALHR 252 Query: 241 GIK 243 GIK Sbjct: 253 GIK 255 >VC0083 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis Vch Vibrio cholerae Length = 260 Score = 327 bits (839), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 154/243 (63%), Positives = 190/243 (78%), Gaps = 3/243 (1%) Query: 4 TTHFGYETVKEEEKVRKVAEVFHSVAAKYDVMNDFMSAGLHRIWKAFTIAQAGVRPGFKV 63 TTHFG+ETV+++EKV KVA+VFHSVAAKYD+MND MS G+HR+WK FTI +G RPG ++ Sbjct: 17 TTHFGFETVRKDEKVHKVAQVFHSVAAKYDIMNDLMSGGIHRLWKRFTIDCSGARPGQRI 76 Query: 64 LDIAGGTGDLSKVFAKQAGPSGEVWLTDINESMLRVGRDRLLNKGIVTPT--MLCDAEKL 121 LD+ GGTGDL+ F++ G G V L DIN SML VGRD+L + G+V + +AE+L Sbjct: 77 LDLGGGTGDLTAKFSRIVGEKGHVILADINNSMLNVGRDKLRDSGVVGNVHYVQANAEEL 136 Query: 122 PFPDNYFDRVSVAFGLRNMTHKDAALAEMRRVLKPGGKLLVLEFSK-VWEPLKKPYDVYS 180 PFPDNYFD ++++F LRN+T KD AL M RVLKPGG+LLVLEFSK + EPL K YD YS Sbjct: 137 PFPDNYFDCITISFCLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPILEPLSKLYDTYS 196 Query: 181 FSVLPWLGKKVANDADSYRYLAESIRMHPDQENLKQMMEQAGLERVQYFNLTAGVAALHT 240 F +LP +G+ +ANDADSYRYLAESIRMHPDQE LK MME+AG E+ Y+NLT G+ ALH Sbjct: 197 FHILPKMGQLIANDADSYRYLAESIRMHPDQETLKGMMEEAGFEQTTYYNLTGGIVALHR 256 Query: 241 GIK 243 G K Sbjct: 257 GYK 259