BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.3714.p (233 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value HI0090 [R] COG0325 Predicted enzyme with a TIM-barrel fold Hin H... 261 8e-70 VC0461 [R] COG0325 Predicted enzyme with a TIM-barrel fold Vch V... 261 1e-69 RSc2683 [R] COG0325 Predicted enzyme with a TIM-barrel fold Rso ... 259 3e-69 PA0394 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pae P... 256 2e-68 PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu P... 253 3e-67 >HI0090 [R] COG0325 Predicted enzyme with a TIM-barrel fold Hin Haemophilus influenzae Length = 237 Score = 261 bits (668), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 128/234 (54%), Positives = 169/234 (72%), Gaps = 6/234 (2%) Query: 3 SIAQRLQLVQQQIARATQEAGRASASVQLLAVSKTFGPQAVAEAVQAGQRAFGENYLQEA 62 +I L L+QQ+I A +E R +V+LLAVSKT A+ A QAGQ AFGENY+QE Sbjct: 2 NIQHNLNLIQQKIETACKEENRNQNTVKLLAVSKTKPISAILSAYQAGQTAFGENYVQEG 61 Query: 63 LDKIAAMPSLVPGIALEWHFIGPIQSNKTRPIAEHFAWVHSVDRLKIAQRLSEQRPAELG 122 ++KI S GI LEWHFIGP+QSNKTR +AEHF W+ ++DR KIA RL+EQRP Sbjct: 62 VEKIQYFES--QGINLEWHFIGPLQSNKTRLVAEHFDWMQTLDRAKIADRLNEQRPTNKA 119 Query: 123 PLNICLQVNISGEASKSGLSPQELPAVAAQVAQLPHLRLRGLMAIPAPSENPAQQRAAFA 182 PLN+ +Q+NIS E SKSG+ P+E+ +A + LPHL LRGLMAIPAP++N A+Q AF Sbjct: 120 PLNVLIQINISDEESKSGIQPEEMLTLAKHIENLPHLCLRGLMAIPAPTDNIAEQENAFR 179 Query: 183 AVRGLYEQLRQSGLP---LDTLSMGMSADLEAALAEGASIVRIGSAIFGARHYA 233 + L+EQL+Q LP +DTLSMGM+ D+ +A+ G+++VRIG+AIFGAR+Y+ Sbjct: 180 KMLELFEQLKQV-LPNQQIDTLSMGMTDDMPSAIKCGSTMVRIGTAIFGARNYS 232 >VC0461 [R] COG0325 Predicted enzyme with a TIM-barrel fold Vch Vibrio cholerae Length = 236 Score = 261 bits (667), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 132/233 (56%), Positives = 168/233 (72%) Query: 1 MSSIAQRLQLVQQQIARATQEAGRASASVQLLAVSKTFGPQAVAEAVQAGQRAFGENYLQ 60 M SI Q ++ + QI A Q+ GRA +SVQLLAVSKT +A+ EA QAGQR FGENY+Q Sbjct: 1 MRSIQQNIEHITAQIESAQQKCGRARSSVQLLAVSKTKPVEAILEATQAGQRYFGENYVQ 60 Query: 61 EALDKIAAMPSLVPGIALEWHFIGPIQSNKTRPIAEHFAWVHSVDRLKIAQRLSEQRPAE 120 E +DKI P +ALEWHFIGP+QSNKTR +AEHF WVH++DR KIA RLSEQRP Sbjct: 61 EGVDKIRYFAEHHPQLALEWHFIGPLQSNKTRLVAEHFDWVHTIDREKIALRLSEQRPVN 120 Query: 121 LGPLNICLQVNISGEASKSGLSPQELPAVAAQVAQLPHLRLRGLMAIPAPSENPAQQRAA 180 + PL + +QVN SGEASKSG+ PQ+L +A +++LP+L LRGLM+IP + Q AA Sbjct: 121 MPPLQVLIQVNTSGEASKSGIEPQQLFTLAELISRLPNLTLRGLMSIPENVPDYPAQLAA 180 Query: 181 FAAVRGLYEQLRQSGLPLDTLSMGMSADLEAALAEGASIVRIGSAIFGARHYA 233 F + L +QL Q +DTLSMGMS D++AA+ G++IVRIG+AIFG R Y+ Sbjct: 181 FTQLAELQQQLAQKYPQIDTLSMGMSGDMQAAIEAGSTIVRIGTAIFGERDYS 233 >RSc2683 [R] COG0325 Predicted enzyme with a TIM-barrel fold Rso Ralstonia solanacearum Length = 240 Score = 259 bits (663), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 147/236 (62%), Positives = 177/236 (75%), Gaps = 3/236 (1%) Query: 1 MSSIAQRLQLVQQQIARATQEAGRASASVQLLAVSKTFGPQAVAEAVQAGQRAFGENYLQ 60 MS IA LQ V+Q+I A A R ASV LLAVSKTF AV A AGQR FGENY+Q Sbjct: 1 MSVIAANLQAVRQRITTACTLASRDPASVTLLAVSKTFDADAVRAAHAAGQRLFGENYVQ 60 Query: 61 EALDKIAAMPSLVPGI-ALEWHFIGPIQSNKTRPIAEHFAWVHSVDRLKIAQRLSEQRPA 119 E K +A+ L G A+ WHFIGP+QSNKTR +AEHF WVHS+DRLKIA+RLS QRPA Sbjct: 61 EGTAKTSALTDLRNGPEAIAWHFIGPLQSNKTRAVAEHFDWVHSIDRLKIAERLSAQRPA 120 Query: 120 ELGPLNICLQVNISGEASKSGLSPQ--ELPAVAAQVAQLPHLRLRGLMAIPAPSENPAQQ 177 L PL +CL++NIS +ASK G+ P E+ +A VA LP LRLRGLMA+P P+++PA + Sbjct: 121 TLPPLQVCLEINISRQASKHGVPPDLDEVLPLARAVAALPRLRLRGLMAVPEPADDPAAR 180 Query: 178 RAAFAAVRGLYEQLRQSGLPLDTLSMGMSADLEAALAEGASIVRIGSAIFGARHYA 233 RA FAA+R L ++L +GLP+DTLSMGMSADLE A+AEGA+IVR+GSAIFGAR YA Sbjct: 181 RAPFAALRDLADRLCAAGLPVDTLSMGMSADLEDAIAEGATIVRVGSAIFGARQYA 236 >PA0394 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pae Pseudomonas aeruginosa Length = 230 Score = 256 bits (655), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 153/232 (65%), Positives = 172/232 (74%), Gaps = 7/232 (3%) Query: 1 MSSIAQRLQLVQQQIARATQEAGRASASVQLLAVSKTFGPQAVAEAVQAGQRAFGENYLQ 60 MS+IA+ + V +I A Q AGR A+V LLAVSKT AV EA AG R FGENYLQ Sbjct: 1 MSTIAENIAKVAARIREAAQAAGRDPATVGLLAVSKTKPAAAVREAHAAGLRDFGENYLQ 60 Query: 61 EALDKIAAMPSLVPGIALEWHFIGPIQSNKTRPIAEHFAWVHSVDRLKIAQRLSEQRPAE 120 EAL K A + L L WHFIGPIQSNKTRPIAEHF WVHSVDRLKIAQRLSEQRPA Sbjct: 61 EALGKQAELADL----PLNWHFIGPIQSNKTRPIAEHFQWVHSVDRLKIAQRLSEQRPAG 116 Query: 121 LGPLNICLQVNISGEASKSGLSPQELPAVAAQVAQLPHLRLRGLMAIPAPSENPAQQRAA 180 L PLN+CLQVN+SGEASKSG +P++LPA+A V QLP+LRLRGLMAIP P+ A Q AA Sbjct: 117 LPPLNVCLQVNVSGEASKSGCAPEDLPALAEAVKQLPNLRLRGLMAIPEPTAERAAQHAA 176 Query: 181 FAAVRGLYEQLRQSGLPLDTLSMGMSADLEAALAEGASIVRIGSAIFGARHY 232 FA +R L L LDTLSMGMS DLEAA+ EGA+ VRIG+A+FGAR Y Sbjct: 177 FARLRELLLDLNLG---LDTLSMGMSDDLEAAIGEGATWVRIGTALFGARDY 225 >PM0112 [R] COG0325 Predicted enzyme with a TIM-barrel fold Pmu Pasteurella multocida Length = 233 Score = 253 bits (645), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 125/234 (53%), Positives = 168/234 (71%), Gaps = 6/234 (2%) Query: 3 SIAQRLQLVQQQIARATQEAGRASASVQLLAVSKTFGPQAVAEAVQAGQRAFGENYLQEA 62 +I Q L +QQ I A Q+A R ++V+LLAVSKT + + +A QAGQ AFGENY+QE Sbjct: 2 TIEQNLAQIQQNIQHAVQQAKRPESAVKLLAVSKTKPVEDIYQAYQAGQTAFGENYVQEG 61 Query: 63 LDKIAAMPSLVPGIALEWHFIGPIQSNKTRPIAEHFAWVHSVDRLKIAQRLSEQRPAELG 122 ++KI I LEWHFIGP+QSNKT+ +AEHF W+ ++DR KIA RL+EQRP Sbjct: 62 VEKIQYFAQ--KNIPLEWHFIGPLQSNKTKLVAEHFDWMQTLDRKKIADRLNEQRPHYKK 119 Query: 123 PLNICLQVNISGEASKSGLSPQELPAVAAQVAQLPHLRLRGLMAIPAPSENPAQQRAAFA 182 PLN+ +Q+NIS E SKSG+ P E+ +A Q+ LPHL LRGLMAIPAP+++ A Q AF Sbjct: 120 PLNVLIQINISDEDSKSGIQPNEMLDLAKQIQNLPHLCLRGLMAIPAPTDDLATQEQAFT 179 Query: 183 AVRGLYEQLRQSGLP---LDTLSMGMSADLEAALAEGASIVRIGSAIFGARHYA 233 + L+EQL+Q+ LP +DTLSMGM+ D+ +A+ G+++VRIG+AIFGAR Y+ Sbjct: 180 QMHSLFEQLKQA-LPDAQIDTLSMGMTDDMASAIQCGSTMVRIGTAIFGARDYS 232